73 Works

Third Lockdown Crime Effects in England and Wales

Anthony Dixon, Graham Farrell & Shane Johnson
The third national lockdown began early January 2021 and started to ease on 8th March when schools and limited outdoor social contact resumed. Police-recorded crime rates per 10,000 population (in orange) are here compared to expected rates (black lines, with confidence intervals in grey). Crime effects in January and February 2021 were similar to first lockdown (Apr-Jun 2020) but with notable differences. Acquisitive crime except bike theft fell sharply but began to increase in March....

Mg/Ca ratios from multiple species of planktonic foraminifera from the Middle Miocene to modern from multiple sites in the global ocean

E.M. Mawbey, F. Boscolo-Galazzo, B.S. Wade & P.N. Pearson
Mg/Ca in multiple species of planktonic foraminifera from five time slices since the Middle Miocene to present (target ages 15, 12.5, 10, 7.5, 4.5, 2.5 and 0 Ma). These samples are from a range of globally and latitudinally distributed DSDP (Deep Sea Drilling Program), ODP (Ocean Drilling Program), IODP (International Ocean Discovery Program) open ocean sites. From low to high latitudes these are: Site U1338, U1489 (Eastern and Western Equatorial Pacific), Sites 871, 872, and...

The Unfamiliar Grey Matter(s): Talking Brains

Andy Ash

Image-based deep learning reveals the responses of human motor neurons to stress and VCP-related ALS

Rickie Patani & Raphaelle Luisier
The aim of the study was to investigate relationships between ALS-related RNA-binding proteins and ALS, under different stress conditions.

Energy Modelling in the UK: Strengths and weaknesses of UK energy models

Pei-Hao Li & Neil Strachan
This paper is the second of four to explore results from UKERC’s Modelling Hub survey. It focuses on four key areas, looking at how models deal with time, space, technologies and behaviour.

Black Lives, British Justice: Black People in London Criminal Justice Records, 1720-1841

Adam Crymble & Emma Azid

Full-likelihood genomic analysis clarifies a complex history of species divergence and introgression: the example of the erato-sara group of Heliconius butterflies

Yuttapong Thawornwattana, Fernando Seixas, Ziheng Yang & James Mallet
Introgression plays a key role in adaptive evolution and species diversification in many groups of species. However, frequent hybridization and gene flow between species makes estimation of the species phylogeny and key population parameters challenging. Here, we show that by accounting for phasing and by using full-likelihood analysis methods, introgression histories and population parameters can be estimated reliably from whole-genome sequence data. We employ full-likelihood methods under the multispecies coalescent (MSC) model with and without...

Analysis of independent cohorts of outbred CFW mice reveals novel loci for behavioral and physiological traits and identifies factors determining reproducibility

Jennifer Zou, Shyam Gopalakrishnan, Clarissa Parker, Jerome Nicod, Richard Mott, Na Cai, Arimantas Lionikas, Robert Davies, Abraham Palmer & Jonathan Flint
Combining samples for genetic association is standard practice in human genetic analysis of complex traits, but is rarely undertaken in rodent genetics. Here, using 23 phenotypes and genotypes from two independent laboratories, we obtained a sample size of 3,076 commercially available outbred mice and identified 70 loci, more than double the number of loci identified in the component studies. Fine-mapping in the combined sample reduced the number of likely causal variants, with a median reduction...

Bushmeat yields, species extinction rates and ecosystem-level impacts of bushmeat harvesting as predicted by the Madingley General Ecosystem Model

Tatsiana Barychka, Georgina Mace & Drew Purves
The datasets contain data generated using the Madingley General Ecosystem Model for experiments decribed in the paper: "T. Barychka, G.M.Mace and D.W.Purves (2021) The Madingley General Ecosystem Model predicts bushmeat yields, species extinction rates and ecosystem-level impacts of bushmeat harvesting. Oikos." The Madingley General Ecosystem Model was used to generate predictions of bushmeat yields, extinction rates and broader ecosystem impacts for a range of harvesting intensities of duiker-sized endothermic herbivores. Duiker antelope (such as Cephalophus...

Data from: Palaeontology meets metacommunity ecology: The Maastricthian dinosaur fossil record of North America as a case study

Jorge García-Girón, Jani Heino, Janne Alahuhta, Alfio Alessandro Chiarenza & Steve Brusatte
Documenting the patterns and potential associated processes of ancient biotas has always been a central challenge in palaeontology. Over the last decades, intense debate has focused on the organisation of dinosaur–dominated communities, yet no general consensus has been reached on how these communities were organised in a spatial context and if primarily affected by abiotic or biotic agents. Here, we used analytical routines typically applied in metacommunity ecology to provide novel insights into dinosaurian distributions...

Immigrant males’ memory acts to reduce ranging overlap and mating competition in wild baboons

Julien Collet, Nathalie Pettorelli, Alice Baniel, Alecia Carter, Elise Huchard, Andrew King, Alexander Lee, Harry Marshall & Guy Cowlishaw
Mechanistic models suggest that information acquired by animals (“knowledge”) could shape home range patterns and dynamics, and how neighbours share space. In social species this would suggest that immigrants could bring new knowledge into social groups, potentially affecting the dynamics of home range overlap. We tested this “immigrant knowledge hypothesis” in a wild population of chacma baboons (Papio ursinus). We used data collected between 2005 and 2013 on two neighbouring troops in Namibia, comprising GPS...

Indoor Residual Spraying (IRS) Impact Evaluation Survey 2009

Arianna Legovini, Pedro Carneiro &

Energy Modelling in the UK: Decision making in government and industrys

Pei-Hao Li & Neil Strachan
This paper is the last of four to explore results from UKERC's Modelling Hub survey. It focuses on how models have underpinned decision making on the transition of the energy system.

How bulk and surface properties of Ti4SiC3, V4SiC3, Nb4SiC3 and Zr4SiC3 tune reactivity: a computational study - data

Matthew Quesne, Nora H De Leeuw & C Richard A Catlow
The bulk and surface properties of early transition metal silicon carbides as well as their activity towards the reduction of CO2 is examined in this first principles DFT study. Data for basal (0001) planes of Ti4C3Si, V4C3Si, Nb4C3Si & Zr4C3Si is stored in one .xlsx file. The first sheet gives formation energies for each silicon carbide as related to the parent monocarbide material. Sheet 2 gives the density of states for each material. Sheet 3...

Data from: Sex differences in costly signalling in rural Western China

Dongzhi Cairang, Erhao Ge & Ruth Mace
Numerous empirical studies suggest that individuals convey their commitment to communities and impart the qualities of being a reliable partner through costly behaviours. We collected religious practices data ranging from daily trivial practices to infrequent grand distant pilgrimages in an agricultural Tibetan village. We predict that 1) villagers who invest more in religious practices are more likely to be nominated as having various prosocial qualities. 2) Investment in grand distant pilgrimages has more efficacy than...

Design of a custom-made device for real-time optical measurement of differential mineral concentrations in 3D scaffolds for bone tissue engineering

Joseph Lovecchio, Valentina Betti, Marilisa Cortesi, Enrico Ravagli, Stefano Severi & Emanuele Giordano
Monitoring bone tissue engineered constructs during their maturation is important to ensure the quality of applied protocols. Several destructive, mainly histochemical, methods are conventionally used to this aim, requiring the sacrifice of the investigated samples. This implies i) to plan several scaffold replicates, ii) expensive and time consuming procedures and iii) to infer the maturity level of a given tissue construct from a cognate replica. To solve these issues, non-destructive techniques such as light spectroscopy-based...

Iron-Nickel-Sulfide Characterisation and Catalytic Testing Data

Claire Mitchell, David Santos-Carballal, Andrew M Beale, Wilm Jones, Sankar Meenakshisundaram & Nora H De Leeuw
Catalytic data describing the production of formate from the hydrogenation of CO2 using iron-sulfide, iron-nickel-sulphide and nickel-sulfide catalysts prepared with different heat treatments under a range of reaction conditions. Catalyst characterisation of these materials include XRD analysis, giving an understanding of the violarite phase and crystallinity. XPS analysis gains understanding of the iron, nickel and sulphur species, and how sulphide and oxide species change under thermal oxidation. XAS analysis employed is vital to gain more...

Free energy calculations of noble-gas containing liquid iron and silicate melt

Y Li
Free energy calculations of noble-gas containing liquid iron and silicate melts at 50 GPa (3500 K) and 135 GPa (4200 K). The chemical potentials of noble gases can be obtained from these calculations. The Gibbs free energy of a series of iron and silicate melts with different concentrations of He were calculated. Then the chemical potentials of He can be derived from the concentration dependent Gibbs free energies. The chemical potentials of Ne, Ar, Kr...

Energy modelling in the UK: The modelling landscape

Neil Strachan & Pei-Hao Li
This paper is the first of four to explore results from UKERC’s Modelling Hub survey. Focusing on the UK energy modelling landscape, these initial findings detail who hosts and runs models, their methodologies and coverage, and their major outputs.

A reassessment of the enigmatic diapsid Paliguana whitei and the early history of Lepidosauromorpha

David Paul Ford, Susan Evans, Jonah Choiniere, Vincent Fernandez & Roger Benson
Lepidosaurs include lizards, snakes, amphisbaenians and the tuatara, comprising a highly speciose evolutionary radiation with widely varying anatomical traits. Their stem-lineage originated by the late middle Permian 259 million years ago, but its early fossil record is poorly documented, obscuring the origins of key anatomical and functional traits of the group. Paliguana whitei, from the Early Triassic of South Africa, is an enigmatic fossil species with potential to provide information on this. However, its anatomy...

Imaging mass cytometry data: Head and neck squamous cell carcinoma tissue section

Jessica Timms, James Opzoomer, Kevin Blighe, Thanos Mourikis, Nicolas Chapuis, Richard Bekoe, Sedigeh Kareemaghay, Paola Nocerino, Mahvash Tavassoli, Claire Harrison, Francesca Ciccarelli, Peter Parker, James Arnold, Benedetta Apollonio, Alan Ramsay, Michaela Fontenay, Paul Barber, James Arnold & Shahram Kordasti
High dimensional cytometry is an innovative tool for immune monitoring in health and disease, it has provided novel insight into the underlying biology as well as biomarkers for a variety of diseases. However, the analysis of multiparametric “big data” usually requires specialist computational knowledge. Here we describe ImmunoCluster (https://github.com/kordastilab/ImmunoCluster) an R package for immune profiling cellular heterogeneity in high dimensional liquid and imaging mass cytometry, and flow cytometry data, designed to facilitate computational analysis by...

Structural brain network abnormalities and the probability of seizure recurrence after epilepsy surgery: supplementary material

Nishant Sinha, Yujiang Wang, Nádia Moreira Da Silva, Anna Miserocchi, Andrew McEvoy, Jane De Tisi, Sjoerd Vos, Gavin Winston, John Duncan & Peter Taylor
Objective: We assessed pre-operative structural brain networks and clinical characteristics of patients with drug resistant temporal lobe epilepsy (TLE) to identify correlates of post-surgical seizure recurrences. Methods: We examined data from 51 TLE patients who underwent anterior temporal lobe resection (ATLR) and 29 healthy controls. For each patient, using the preoperative structural, diffusion, and post-operative structural MRI, we generated two networks: ‘pre-surgery’ network and ‘surgically-spared’ network. Standardising these networks with respect to controls, we determined...

REMI-seq analysis of D. discoideum cells treated with Lithium or Valproic acid

Christopher Thompson
A critical aspect of toxicity evaluation is developmental and reproductive toxicity (DART) testing. Traditionally, DART testing has been conducted in vivo in mammalian model systems. New legislation aimed at reducing animal use and the prohibitive costs associated with DART testing, together with a need to understand the genetic pathways underlying developmental toxicity means there is a growing demand for alternative model systems for toxicity evaluation. Here we explore the potential of the eukaryotic social amoeba...

Risky decision and happiness task: The Great Brain Experiment smartphone app

Robb B. Rutledge
This resource consists of data from a risky decision and happiness task that was part of The Great Brain Experiment (GBE) smartphone app. Data were collected from 47,067 participants aged 18+ between March 8, 2013 and October 5, 2015. These anonymous unpaid participants completed the task a total of 91,058 times making approximately 2.7 million choices and 1.1 million happiness ratings in total. This resource represents at least 6,000 hours of task data. A subset...

Quantitative assessment of agricultural sustainability reveals divergent priorities among nations

Guolin Yao, Xin Zhang, Srishti Vishwakarma, Carole Dalin, Adam Komarek, David Kanter, Kyle Davis, Kimberly Pfeifer, Jing Zhao, Tan Zou, Paolo D'Odorico, Christian Folberth, Fernando Galeana Rodriguez, Jessica Fanzo, Lorenzo Rosa, William Dennison, Mark Musumba, Amy Heyman & Eric Davidson
Agriculture is fundamental to all three pillars of sustainability, environment, society, and economy. However, the definition of sustainable agriculture and capacities to measure it remain elusive. Independent and transparent measurements of national sustainability are needed to gauge progress, encourage accountability, and inform policy. Here, we developed a Sustainable Agriculture Matrix (SAM) to quantify national performance indicators in agriculture and to investigate the tradeoffs and synergies based on historical data for most countries of the world....

Registration Year

  • 2021

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  • Conference Paper
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  • University College London
  • The Francis Crick Institute
  • King's College London
  • University of Leeds
  • Centre national de la recherche scientifique
  • University of Glasgow
  • University of Cambridge
  • University of Birmingham
  • Cardiff University
  • University of Oxford