119 Works

Data from: Palaeontology meets metacommunity ecology: The Maastricthian dinosaur fossil record of North America as a case study

Jorge García-Girón, Jani Heino, Janne Alahuhta, Alfio Alessandro Chiarenza & Steve Brusatte
Documenting the patterns and potential associated processes of ancient biotas has always been a central challenge in palaeontology. Over the last decades, intense debate has focused on the organisation of dinosaur–dominated communities, yet no general consensus has been reached on how these communities were organised in a spatial context and if primarily affected by abiotic or biotic agents. Here, we used analytical routines typically applied in metacommunity ecology to provide novel insights into dinosaurian distributions...

The Unfamiliar Grey Matter(s): Talking Brains

Andy Ash

Mg/Ca ratios from multiple species of planktonic foraminifera from the Middle Miocene to modern from multiple sites in the global ocean

E.M. Mawbey, F. Boscolo-Galazzo, B.S. Wade & P.N. Pearson
Mg/Ca in multiple species of planktonic foraminifera from five time slices since the Middle Miocene to present (target ages 15, 12.5, 10, 7.5, 4.5, 2.5 and 0 Ma). These samples are from a range of globally and latitudinally distributed DSDP (Deep Sea Drilling Program), ODP (Ocean Drilling Program), IODP (International Ocean Discovery Program) open ocean sites. From low to high latitudes these are: Site U1338, U1489 (Eastern and Western Equatorial Pacific), Sites 871, 872, and...

Third Lockdown Crime Effects in England and Wales

Anthony Dixon, Graham Farrell & Shane Johnson
The third national lockdown began early January 2021 and started to ease on 8th March when schools and limited outdoor social contact resumed. Police-recorded crime rates per 10,000 population (in orange) are here compared to expected rates (black lines, with confidence intervals in grey). Crime effects in January and February 2021 were similar to first lockdown (Apr-Jun 2020) but with notable differences. Acquisitive crime except bike theft fell sharply but began to increase in March....

Predictors and rates of PTSD, depression and anxiety in UK frontline health and social care workers during COVID-19

Talya Greene, Jasmine Harju-Seppänen, Mariam Adeniji, Charlotte Steel, Nick Grey, Chris R. Brewin, Michael A. Bloomfield & Jo Billings
Background: Studies have shown that working in frontline healthcare roles during epidemics and pandemics was associated with PTSD, depression, anxiety, and other mental health disorders. Objectives: The objectives of this study were to identify demographic, work-related and other predictors for clinically significant PTSD, depression, and anxiety during the COVID-19 pandemic in UK frontline health and social care workers (HSCWs), and to compare rates of distress across different groups of HCSWs working in different roles and...

Predictors and rates of PTSD, depression and anxiety in UK frontline health and social care workers during COVID-19

Talya Greene, Jasmine Harju-Seppänen, Mariam Adeniji, Charlotte Steel, Nick Grey, Chris R. Brewin, Michael A. Bloomfield & Jo Billings
Background: Studies have shown that working in frontline healthcare roles during epidemics and pandemics was associated with PTSD, depression, anxiety, and other mental health disorders. Objectives: The objectives of this study were to identify demographic, work-related and other predictors for clinically significant PTSD, depression, and anxiety during the COVID-19 pandemic in UK frontline health and social care workers (HSCWs), and to compare rates of distress across different groups of HCSWs working in different roles and...

A qualitative study of sedentary behaviours in stroke survivors: non-participant observations and interviews with stroke service staff in stroke units and community services

Sarah Morton, Jennifer Hall, Claire Fitzsimons, Jessica Hall, Coralie English, Anne Forster, Rebecca Lawton, Anita Patel, Gillian Mead, David J. & Clarke
Sedentary behaviour (SB) is associated with negative health outcomes and is prevalent post-stroke. This study explored SB after stroke from the perspective of stroke service staff. Qualitative mixed-methods study. Non-participant observations in two stroke services (England/Scotland) and semi-structured interviews with staff underpinned by the COM-B model of behaviour change. Observations were analysed thematically; interviews were analysed using the Framework approach. One hundred and thirty-two observation hours (October - December 2017), and 31 staff interviewed (January...

Full-likelihood genomic analysis clarifies a complex history of species divergence and introgression: the example of the erato-sara group of Heliconius butterflies

Yuttapong Thawornwattana, Fernando Seixas, Ziheng Yang & James Mallet
Introgressive hybridization plays a key role in adaptive evolution and species diversification in many groups of species. However, frequent hybridization and gene flow between species make estimation of the species phylogeny and key population parameters challenging. Here, we show that by accounting for phasing and using full-likelihood methods, introgression histories and population parameters can be estimated reliably from whole-genome sequence data. We employ the multispecies coalescent (MSC) model with and without gene flow to infer...

Energy Modelling in the UK: Strengths and weaknesses of UK energy models

Pei-Hao Li & Neil Strachan
This paper is the second of four to explore results from UKERC’s Modelling Hub survey. It focuses on four key areas, looking at how models deal with time, space, technologies and behaviour.

Black Lives, British Justice: Black People in London Criminal Justice Records, 1720-1841

Adam Crymble & Emma Azid

A three-wave network analysis of COVID-19's impact on schizotypal traits, paranoia and mental health through loneliness

Keri Ka-Yee Wong, Yi Wang, Gianluca Esposito & Adrian Raine
Background The 2019 coronavirus (COVID-19) pandemic has impacted people’s mental wellbeing. Studies to date have examined the prevalence of mental health symptoms (anxiety, depression, loneliness), yet fewer longitudinal studies have compared across background factors and other psychological variables to identify vulnerable sub-groups. This study tests to what extent higher levels of psychotic-like experiences – indexed by schizotypal traits and paranoia – are associated with various mental health variables 6- and 12-months since April 2020. Methods...

Disentangling interventions to reduce fear of falling in community-dwelling older people: a systematic review and meta-analysis of intervention components

Marlot Kruisbrink, Rik Crutzen, Gertrudis I. J. M. Kempen, Kim Delbaere, Ton Ambergen, Kei Long Cheung, Denise Kendrick, Steve Iliffe & G. A. Rixt Zijlstra
Fear of falling (FoF) is a common and debilitating problem for older people. Most multicomponent interventions show only moderate effects. Exploring the effective components may help in the optimization of treatments for FoF. In a systematic review of five scientific literature databases, we identified randomized controlled trials with older community-dwelling people that included FoF as an outcome. There was no restriction on types of interventions. Two reviewers extracted information about outcomes and content of interventions....

Disentangling interventions to reduce fear of falling in community-dwelling older people: a systematic review and meta-analysis of intervention components

Marlot Kruisbrink, Rik Crutzen, Gertrudis I. J. M. Kempen, Kim Delbaere, Ton Ambergen, Kei Long Cheung, Denise Kendrick, Steve Iliffe & G. A. Rixt Zijlstra
Fear of falling (FoF) is a common and debilitating problem for older people. Most multicomponent interventions show only moderate effects. Exploring the effective components may help in the optimization of treatments for FoF. In a systematic review of five scientific literature databases, we identified randomized controlled trials with older community-dwelling people that included FoF as an outcome. There was no restriction on types of interventions. Two reviewers extracted information about outcomes and content of interventions....

Immigrant males’ memory acts to reduce ranging overlap and mating competition in wild baboons

Julien Collet, Nathalie Pettorelli, Alice Baniel, Alecia Carter, Elise Huchard, Andrew King, Alexander Lee, Harry Marshall & Guy Cowlishaw
Mechanistic models suggest that information acquired by animals (“knowledge”) could shape home range patterns and dynamics, and how neighbours share space. In social species this would suggest that immigrants could bring new knowledge into social groups, potentially affecting the dynamics of home range overlap. We tested this “immigrant knowledge hypothesis” in a wild population of chacma baboons (Papio ursinus). We used data collected between 2005 and 2013 on two neighbouring troops in Namibia, comprising GPS...

Indoor Residual Spraying (IRS) Impact Evaluation Survey 2009

Arianna Legovini, Pedro Carneiro &

Image-based deep learning reveals the responses of human motor neurons to stress and VCP-related ALS

Rickie Patani & Raphaelle Luisier
The aim of the study was to investigate relationships between ALS-related RNA-binding proteins and ALS, under different stress conditions.

AI3SD Video: Automated Chemical Ontology Expansion

Janna Hastings
Ontologies provide a shared vocabulary and semantic resource for a domain. Manual construction enables them to achieve high quality and capture subtle semantic nuances, essential for wide acceptance and applicability across a community. However, the manual curation process does not scale for large domains. I will present a methodology for automatic ontology extension based on deep learning using ontology annotations, and show how we apply this methodology to the ChEBI ontology, a prominent reference ontology...

Energy Modelling in the UK: Decision making in government and industrys

Pei-Hao Li & Neil Strachan
This paper is the last of four to explore results from UKERC's Modelling Hub survey. It focuses on how models have underpinned decision making on the transition of the energy system.

Bushmeat yields, species extinction rates and ecosystem-level impacts of bushmeat harvesting as predicted by the Madingley General Ecosystem Model

Tatsiana Barychka, Georgina Mace & Drew Purves
The datasets contain data generated using the Madingley General Ecosystem Model for experiments decribed in the paper: "T. Barychka, G.M.Mace and D.W.Purves (2021) The Madingley General Ecosystem Model predicts bushmeat yields, species extinction rates and ecosystem-level impacts of bushmeat harvesting. Oikos." The Madingley General Ecosystem Model was used to generate predictions of bushmeat yields, extinction rates and broader ecosystem impacts for a range of harvesting intensities of duiker-sized endothermic herbivores. Duiker antelope (such as Cephalophus...

Analysis of independent cohorts of outbred CFW mice reveals novel loci for behavioral and physiological traits and identifies factors determining reproducibility

Jennifer Zou, Shyam Gopalakrishnan, Clarissa Parker, Jerome Nicod, Richard Mott, Na Cai, Arimantas Lionikas, Robert Davies, Abraham Palmer & Jonathan Flint
Combining samples for genetic association is standard practice in human genetic analysis of complex traits, but is rarely undertaken in rodent genetics. Here, using 23 phenotypes and genotypes from two independent laboratories, we obtained a sample size of 3,076 commercially available outbred mice and identified 70 loci, more than double the number of loci identified in the component studies. Fine-mapping in the combined sample reduced the number of likely causal variants, with a median reduction...

STR/Ort mouse epiphysis (male, 19w, #123.82) CT stack

Eva C. Herbst, Alessandro Felder, Lucinda Evans, Sara Ajami, Behzad Javaheri & Andrew Pitsillides
CT stack of a male, 19-week-old STR/Ort mouse epiphysis .
Voxel size = 0.005 mm
Ethical approval for the animal procedures was carried out in accordance with the Animals (Scientific Procedures) Act 1986, an Act of Parliament of the United Kingdom, approved by the Royal Veterinary College Ethical Review Committee and the United Kingdom Government Home Office.

CBA mouse epiphysis (male, 20wk, #4) CT stack

Eva C. Herbst, Alessandro Felder, Lucinda Evans, Sara Ajami & Behzad Javaheri
CT stack of a male, 20-week-old CBA mouse epiphysis .
Voxel size = 0.005 mm
Ethical approval for the animal procedures was carried out in accordance with the Animals (Scientific Procedures) Act 1986, an Act of Parliament of the United Kingdom, approved by the Royal Veterinary College Ethical Review Committee and the United Kingdom Government Home Office.

Human parietal bone section (male, 5 months, craniosynostosis) CT Stack

Eva C. Herbst, Sara Ajami, Alessandro Borghi, Alessandro Felder, Lucinda Evans, Behzad Javaheri & Andrew Pitsillides
Section of a human cranium of a 5-month-old male with cranial synostosis.
Voxel size: 0.009 mm
The samples were retrieved following ethical approval and patient consent.

Video demonstrating trabecular segmentation of a mouse epiphysis

Eva C. Herbst, Alessandro Felder, Lucinda Evans, Sara Ajami, Behzad Javaheri & Andrew Pitsillides
This video demonstrates our automatic trabecular segmentation method on the tibial epiphysis of a 20 week old CBA mouse. Details of this method can be found on our github repository: https://github.com/evaherbst/Trabecular_Segmentation_Avizo

Video demonstrating trabecular segmentation of a mouse epiphysis

Eva C. Herbst, Alessandro Felder, Lucinda Evans, Sara Ajami & Behzad Javaheri
This video demonstrates our automatic trabecular segmentation method on the tibial epiphysis of a 20 week old CBA mouse. Details of this method can be found on our github repository: https://github.com/evaherbst/Trabecular_Segmentation_Avizo

Registration Year

  • 2021
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Affiliations

  • University College London
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  • North West Agriculture and Forestry University
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  • Zhejiang University
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  • Johns Hopkins University
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  • Jiangsu Academy of Agricultural Sciences
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