1,146 Works

Smoothing Inside of the beehive

Sam Lunn-Rockliffe & Joseph Kimutai Cheptorus
The inside of the beehive is smoothed using an axe and the newly hafted blade.

Changing tool blade

Sam Lunn-Rockliffe & Joseph Kimutai Cheptorus
An axe blade is removed from the handle and hafted onto a long stick.

Collecting resources

Sam Lunn-Rockliffe & Joseph Kimutai Cheptorus
Jacob Komen climbs a tree to cut branches from the Borowo tree (forest dombeya).

Changing tool blade

Sam Lunn-Rockliffe & Joseph Kimutai Cheptorus
An axe blade is removed from the handle and hafted onto a long stick.

Collecting resources

Sam Lunn-Rockliffe & Joseph Kimutai Cheptorus
Amos Ruto climbs a tree to collect branches from the Borowo tree (forest dombeya).

Collecting resources

Sam Lunn-Rockliffe
Richard Murkomen loops together a vine that was collected from the forest. The vine will be used for tying together parts of the beehive during the construction process.

Summary statistics for Alzheimer's disease GWAS on APOE-e4 homozygous individuals in UK Biobank

M Bracher-Smith, G Leonenko, E Baker, K Crawford, A Graham, D Salih, B Howell, J Hardy & V Escott-Price
We conducted a genome-wide association study in a sample of 5,390 APOE-ε4 homozygous (ε4ε4) individuals (288 cases and 5,102 controls) aged 65 or over in the UK Biobank. Results are the summary statistics from a GWAS conducted in Plink using age, sex and the first 15 principal components as covariates. There are 5,349,830 rows and 9 columns. Each row corresponds to a variant. Columns are: CHR, BP, SNP, A1, A2_counted_allele, OR, SE_beta, Z_STAT and P....

Should more patients be offered repair for mitral valve endocarditis? a single-centre 15-year experience

Clarissa Ng Yin Ling, David Bleetman, Soumik Pal, Hing Chi Kristie Leung, Habib Khan, Donald Whitaker, Olaf Wendler, Ranjit Deshpande & Max Baghai
Abstract Objective To describe the long-term outcomes of mitral valve repair (MVr) versus mitral valve replacement (MVR) in patients with native valve infective endocarditis (IE) at a centre with high-repair rates. Methods We conducted a retrospective single-centre cohort study. From 2005 to 2021, 183 patients with active or healed native valve IE were included. The primary outcome was long-term mortality. Patient status was last confirmed 31 March 2021. Secondary outcomes were post-operative MR, MV reoperation,...

T-72 SAR data dome (Remote Sensing: 0.25λ)

Michael Woollard
This dataset contains a data dome of simulated compensated phase history data (CPHD) files for a T-72 main battle tank target. These outputs were produced using the SARCASTIC v2.0 simulator (Remote Sens. 2022, 14(11), 2561; https://doi.org/10.3390/rs14112561).In this archive, the following configuration was used: No ground plane Ray-tube sizing: 0.25 λ Point spread function emulation Each simulated file follows the naming convention "T72B-ddome-X-Y.sarc.cph", where X is the azimuth and Y is the elevation at the centre...

T-72 SAR data dome (Remote Sensing: 0.25λ, no PSF)

Michael Woollard
This dataset contains a data dome of simulated compensated phase history data (CPHD) files for a T-72 main battle tank target. These outputs were produced using the SARCASTIC v2.0 simulator (Remote Sens. 2022, 14(11), 2561; https://doi.org/10.3390/rs14112561).In this archive, the following configuration was used: No ground plane Ray-tube sizing: 0.25 λ No point spread function emulation Each simulated file follows the naming convention "T72B-ddome-X-Y.sarc.cph", where X is the azimuth and Y is the elevation at the...

Additional file 1 of GATA-type transcriptional factor SpGAT1 interacts with SpMIG1 and promotes lipid accumulation in the oleaginous yeast $$Saitozyma \ podzolica$$ S a i t o z y m a p o d z o l i c a zwy-2-3

Yulu Ran, Hui Xu, Qingzhuoma Yang, Yi Xu, Huahao Yang, Dairong Qiao & Yi Cao
Additional file 1: Table S1. Strains and plasmids. Table S2. Primers for gene amplification and qRT-PCR. Table S3. cDNA sequence of SpGAT1 and SpMIG1.

Additional file 1 of Implementing service transformation for children and adolescents with eating disorders across England: the theory, politics, and pragmatics of large-scale service reform

Ivan Eisler, Mima Simic, Peter Fonagy & Rachel Bryant-Waugh
Additional file 1: Table S1. Outline programme of National Whole Team training.

The impact of circadian rhythms on the immune response to influenza vaccination in middle-aged and older adults (IMPROVE): a randomised controlled trial

Yihao Liu, Hui Zhang, Gang Yuan, Mi Yao, Bin Li, Jianying Chen, Yuling Fan, Ruohui Mo, Fenghua Lai, Xinwen Chen, Mengyuan Li, Binfeng Chen, Janet M. Lord, Sui Peng, KarKeung Cheng & Haipeng Xiao
Abstract Background Vaccination is important in influenza prevention but the immune response wanes with age. The circadian nature of the immune system suggests that adjusting the time of vaccination may provide an opportunity to improve immunogenicity. Our previous cluster trial in Birmingham suggested differences between morning and afternoon vaccination for some strains in the influenza vaccine in older adults. Whether this effect is also seen in a younger age group with less likelihood of compromised...

sj-docx-1-tag-10.1177_17562848221127474 – Supplemental material for Associations between inflammatory bowel disease, social isolation, and mortality: evidence from a longitudinal cohort study

Jie Chen, Jiawei Geng, Jiayi Wang, Zhenhua Wu, Tian Fu, Yuhao Sun, Xuejie Chen, Xiaoyan Wang & Therese Hesketh
Supplemental material, sj-docx-1-tag-10.1177_17562848221127474 for Associations between inflammatory bowel disease, social isolation, and mortality: evidence from a longitudinal cohort study by Jie Chen, Jiawei Geng, Jiayi Wang, Zhenhua Wu, Tian Fu, Yuhao Sun, Xuejie Chen, Xiaoyan Wang and Therese Hesketh in Therapeutic Advances in Gastroenterology

Associations between inflammatory bowel disease, social isolation, and mortality: evidence from a longitudinal cohort study

Jie Chen, Jiawei Geng, Jiayi Wang, Zhenhua Wu, Tian Fu, Yuhao Sun, Xuejie Chen, Xiaoyan Wang & Therese Hesketh
Background:Social well-being of patients with inflammatory bowel disease (IBD) is garnering increased attention; however, the impact of social isolation remained poorly understood.Objectives:We investigated the joint association of social isolation and IBD with premature deaths to articulate the profound impact of social isolation in IBD prognosis.Design:Longitudinal cohort study.Methods:We leveraged data of 486,014 participants from UK Biobank (including 5791 with IBD), the mean follow-up was 11.84 years. Diagnoses of IBD and its subtypes of Crohn’s disease (CD)...

Efficient cell navigation methods and applications of an aperture 4 hexagonal discrete global grid system

Jianbin Zhou, Jin Ben, Xinhai Huang, Rui Wang, Xiaoyu Liang, Junjie Ding & Qishuang Liang
Hexagonal discrete global grid systems are multi-resolution frameworks for earth data and have attracted much attention in research towards the next generation of geographic information system. Each resolution of the framework divides the earth into a hexagonal grid of cells and cell codes are used instead of Cartesian coordinates to organize and query data. Aperture (the ratio of cells between resolutions) 4 systems have structural advantages compared with aperture 3 and 7, but haven’t been...

Processed Plaque-2.0 infection scores of the PCL screen for HSV, imaged and analysed at UZH.

Dominik Olszewski, Fanny Georgi, Luca Murer, Vardan Andriasyan, Fabien Kuttler, Gerardo Turcatti, Urs Greber & Artur Yakimovich
virus indicates virus genotype, the PCL was tested against, compoundIdentifier indicates the UZH identifier for blinded testing by UZH, PCL_ID and compoundName disclose the PCL compound identifier and name, respectively. Barcode1, Barcode2, and Barcode3 indicate on which screening plates, given by the screening plate sequence number defined by EPFL, the PCL compound was tested on. The PrestoBlue toxicity scoring of the compound tested in noninfected cells is given as 1 (toxic) and 0 (non-toxic) in...

Vascular Models

Sharp Lo & Jon McCullough
These are the five-outlets model and the profunda femoris model used in the referenced paper.
The five-outlets model is composed by joining five identical short pipes and a longer pipe all converging on a single point. It is a simplified model of the aortic arch with five branches.
The profunda femoris model is extracted from the anatomical model given in the reference. It is a model of an artery in the right thigh...

Additional file 2 of Early brass from the Foyemiaowan-Xindiantai cemetery, 265–439 ce: the origin and diffusion of brass in ancient China

Qiangbing Wei, Yanxiang Li, Thilo Rehren, Honglian Ma, Xiuhui Li & Jianli Chen
Additional file 2: Table S2.

The Curious Role of COVID-19 in Sentencing: The Relevance and Mitigating Weight of Ill Health and Harsh Prison Conditions

Brendon Murphy, John Anderson & Mirko Bagaric
Australian courts have held that the COVID-19 pandemic should impact on the nature and severity of criminal sanctions. Broadly, it has been argued that prisoners are more likely to be infected with COVID-19, to experience adverse outcomes because of existing compromised health conditions, and to experience more onerous incarceration due to lengthy periods in lockdown. The courts, on balance, have been sympathetic to these and other arguments, and accordingly have been willing to extend a...

VaxPac Study: UK Report

Keri Ka-Yee Wong
The VaxPac Study aims to understand the decisions and reasons behind vaccine acceptance and hesitancy of parents with children under age 18 in the UK and Japan. This is a summary report of UK parents.

Raw Data for \"On-demand cell-autonomous gene therapy for brain circuit disorders\", Qiu et al. 2022 Science

Gabriele Lignani, Nathanael O'Neill, Yichen Qiu, Benito Maffei & Clara Zourray
Raw Data for Qui et al. 2022 10.1126/science.abq6656
On-demand cell-autonomous gene therapy for brain circuit disorders Yichen Qiu, Nathanael O’Neill, Benito Maffei, Clara Zourray, Amanda Almacellas Barbanoj, Jenna C. Carpenter,Steffan P. Jones, Marco Leite, Thomas J. Turner, Francisco C. Moreira, Albert Snowball, Tawfeeq Shekh-Ahmad, Vincent Magloire, Serena Barral, Manju A. Kurian, Matthew C. Walker, Stephanie Schorge, Dimitri M. Kullmann, Gabriele Lignani
Content: EEG MEA Immuno Patch Clamp Electrophysiology
All data are in...

Changes over time in the Chronic Liver Disease risk score predict liver-related outcomes: longitudinal analysis of the Whitehall II study

Fredrik Åberg, Annie Britton & Panu K. Luukkonen
The Chronic Liver Disease (CLivD) risk score was recently shown to predict future advanced liver disease in the general population. We here investigated the impact of individual CLivD-score changes over time. Participants of both phase 3 (baseline, 1991–1994) and phase 5 (follow-up, 1997–1999) examinations of the Whitehall II study were followed for liver-related outcomes (hospitalization, cancer, death) until December 2019 through linkage with electronic healthcare registers. The CLivD score, its modifiable components (alcohol use, waist–hip...

Additional file 10 of Costunolide is a dual inhibitor of MEK1 and AKT1/2 that overcomes osimertinib resistance in lung cancer

Xueli Tian, Rui Wang, Tingxuan Gu, Fayang Ma, Kyle Vaughn Laster, Xiang Li, Kangdong Liu, Mee-Hyun Lee & Zigang Dong
Supplementary Material 10

Additional file 11 of Costunolide is a dual inhibitor of MEK1 and AKT1/2 that overcomes osimertinib resistance in lung cancer

Xueli Tian, Rui Wang, Tingxuan Gu, Fayang Ma, Kyle Vaughn Laster, Xiang Li, Kangdong Liu, Mee-Hyun Lee & Zigang Dong
Supplementary Material 11

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