980 Works

SENSITIVITY OF ELECTRON-PROTON COINCIDENCE ASYMMETRIES IN NEUTRON BETA-DECAY TO SCALAR AND TENSOR INTERACTIONS

Subash C. Nepal
We study the combined sensitivity of measurements of electron-proton coincidence asymmetries in polarized neutron beta-decay together with a measurement of the electron energy spectrum in unpolarized neutron beta-decay to beyond Standard Model (BSM) scalar and tensor interactions, via the appearance of such BSM physics in the Fierz interference terms b and bv. Whereas measurements of the electron energy spectrum directly probe b, both the proton and neutrino asymmetries for which experimental results exist are not...

NOVEL SMALL MOLECULE ANTIFUNGALS FOR INVASIVE FUNGAL INFECTIONS

Emily Dennis
Human fungal pathogens cause a range of diseases from benign skin conditions (i.e., ringworm) to thrush, mucosal membrane infections, and life-threatening systemic infections including bloodstream infections (i.e., aspergillosis and candidiasis) and Cryptococcal meningitis. These systemic infections occur most often in immunocompromised individuals and have high mortality rates. Current antifungal agents used in the clinic belong to three main classes: the polyenes (e.g., amphotericin B (AmB)), the echinocandins (e.g., caspofungin (CFG)), and the azoles (e.g., fluconazole...

A THEORETICAL AND EXPERIMENTAL STUDY OF CHARGE TRANSPORT IN ORGANIC THERMOELECTRIC MATERIALS AND CHARGE TRANSFER STATES IN ORGANIC PHOTOVOLTAICS

Ashkan Abtahi
Applications of organic electronics have increased significantly over the past two decades. Organic semiconductors (OSC) can be used in mechanically flexible devices with potentially lower cost of fabrication than their inorganic counterparts, yet in many cases organic semiconductor-based devices suffer from lower performance and stability. Investigating the doping mechanism, charge transport, and charge transfer in such materials will allow us to address the parameters that limit performance and potentially resolve them. In this dissertation, organic...

Street Musicians, Soundscapes and Hearing the State in Urban Public Spaces of Istanbul

Laçin Tutalar
This study explores street musicians’ routines and associations with public space in Istanbul, Turkey between 2014 and 2016, a period which corresponds to a new, more conservative routine in the aftermath of a time of political contention in 2013. The study overall takes up a rhythmanalytical perspective, following the cultural geography’s interest based on Henri Lefebvre’s use of the term. I contribute to that interest by paying attention to changes in the composition of an...

Curious Natures

Richard Lee Parmer
This dissertation argues that early American writers often constructed queer ecologies in order to naturalize Anglo-American civilization and justify its expansion into Native American territories. Since there is so little textual evidence on the subject, the major challenge to studying sexuality in early America is approaching sexuality studies creatively—to broaden both our understanding of what counts as sexual discourse and our frameworks for analyzing it. My dissertation addresses this challenge through what many ecocritical scholars...

CARDIAC EFFECTS OF OBESITY DURING PREGNANCY IN C57BL/6J MICE

Kayla Dudick
Objective: Pregnancy requires profound cardiac and metabolic adaptation. Left ventricular (LV) mass is increased in response to pregnancy, but is not associated with cardiac damage. In contrast, obesity-mediated cardiac hypertrophy is pathological. Data from animal studies indicate dietary fatty acid composition may have a protective effect during states of extreme cardiac physiological adaptation. In contrast, aberrant cardiac metabolism is a hallmark of disease. Over a third of reproductive-age women in the United States are obese,...

Incorporating Environmental Arrangement Strategies into Classroom Activities

Brandy Denton
Individuals with extensive support needs, including those who have autism spectrum disorder and are classified as level 3 in the area of social communication, are more likely than same-age peers to display delays in age-appropriate social communication and engagement in activities. To address these issues, special education teachers, in collaboration with related-service providers, should create social communication and engagement objectives. Once objectives are identified, teachers can plan for and implement environmental arrangement (EA) strategies to...

Using Response Cards in Inclusive Classrooms

Kaitlin Ayers
Inclusive classrooms consist of students with and without disabilities. It is often difficult for teachers to find ways to incorporate all students equally in classroom discussions. Often students with disabilities tend to participate less than their typically developing peers. For teachers to be effective in their classroom it is important for them to follow high leverage practices. One high-leverage practice strategy for teachers to incorporate in their classroom is the use of response cards (RCs)....

FLAVODOXIN, THE HYDROGEN ATOM OF FLAVOPROTEINS

Taylor Varner
Flavodoxin is a small, highly stable protein that contain a single FMN cofactor used to transfer single electrons at low potentials. The organism Rhodopseudomonas palustris contains a long-chain flavodoxin. Long-chain flavodoxins are characterized by a 20 amino acid loop that is proposed to allow interactions with partner proteins. We plan to utilize this protein as a model to build our repertoire with protein fluorination and fluorine NMR in flavoproteins. This tool kit will then be...

Improving Retention and Degree Attainment for Underrepresented Students in STEM

Cori Henderson
Experiential learning opportunities, such as undergraduate research, are found to be useful in promoting retention and graduation in STEM majors, and specifically for underrepresented student populations. These opportunities are being implemented throughout the United Stated as a means to improve student learning and persistence. In Kentucky’s strategic plan, experiential learning activities are seen as an avenue to help students persist in college and are key components in helping the commonwealth reach their goal of sixty-percent...

DIDACTIC MARITAL MEDIATION: AN ALTERNATIVE MODEL OF HELPING COUPLES STAY MARRIED

Djidjoho Akloubou Gnonhossou
Mediation is one of the alternative dispute resolution (ADR) methods in which a third party with no decision-making power often facilitates informal talks and listening to address conflicts between concerned parties for possible mutually beneficial solutions (Bush & Folger, 2005; Haynes, 1994; Irving & Benjamin, 1995). When used in helping couples in conflict to reconcile or to strengthen marriages, mediation takes the form of marriage mediation (Boardman, Fiske, Israel, & Neumann, 2009, May; Boardman, 2013)....

ECOSYSTEM OF BAGGED GRAIN STORED UNDER NATURALLY VENTILATED WAREHOUSE: ANALYSIS AND MODELLING

Michael Omodara
Grain in Africa and indeed most developing parts of the world are stored in polypropylene or jute bags arranged in stacks of varied dimensions in naturally ventilated warehouses. This practice is, however, associated with high postharvest losses due to poor temperature and moisture management during storage. This constitutes a major economic and food security challenge in these countries. Therefore, this study characterizes changes in moisture content and temperature occurring in a stack of bagged corn...

Assessing Learning Efficiency In Narrative Simulation Delivered Through Interactive Multimedia

Christopher Daniel
This study evaluated the effects of Narrative Simulation (NS) on learning and cognitive load. Specifically, it measured the potential differences in observed instructional efficiency when comparing a self-paced expository multimedia lesson to a NS lesson which involves a character-focused story with multiple decision inputs at key points. This ex post facto design observed 119 participants consisting of preservice teachers from a large public university in the southeastern United States. They were divided into two sequence...

CERAMIDE-ENRICHED EXTRACELLULAR VESICLES

Ahmed Elsherbini
Alzheimer’s disease (AD) is an age-dependent, progressive, neurodegenerative disorder that is characterized clinically by the impairment of cognitive functions concomitant with behavioral and personality changes. AD is associated with distinct pathological hallmarks, namely, intracellular neurofibrillary tangles comprised of hyperphosphorylated tau protein, extracellular amyloid beta (Aβ) plaques, and marked brain atrophy. Besides their main role as the core component of amyloid plaques, oligomeric Aβ have been shown to be neurotoxic. The exact mechanism of Aβ neurotoxicity...

SIAH-MEDIATED UREGULATION OF THE DEVELOPMENT OF THE VISUAL SYSTEM IN ZEBRAFISH (DANIO RERIO)

Warlen Pereira Piedade
The eye is a complex organ responsible for vision that which formation depends on several intricate developmental steps. Vision for humans is responsible for the majority of its sensory interactions with the environment. Eye development can be divided into two critical stages: morphogenesis, which establishes the eye structure culminating with the fusion of the optic fissure, a transient cleft important for eye vascularization, and subsequently specification and differentiation of the retina to form every type...

USING TRANSCRANIAL DIRECT CURRENT STIMULATION TO IMPROVE NAMING ABILITY IN POST-STROKE APHASIA

Mohammed ALHarbi
Introduction. Aphasia is a devastating acquired language disorder that affects about one third of stroke survivors. Aphasia can severely affect quality of life and can be associated with economic burdens due to the need for long-term communication rehabilitation. Traditional aphasia therapies are known to be effective; however, progress is often slow and limited in severe cases – full restoration of communication abilities is rarely achieved. Thus, there is a critical need for therapeutic solutions that...

Structure and Demographic Correlates of Individual Trait Responses to Emotions

Anita Adams
From a functionalist perspective, emotions inform people of their needs and influence responses to the environment. Responses to emotion encompass more than emotion regulation strategies. Individual differences emerge from the consistent way that people cope with their emotions, called trait responses to emotion (TRE). We hypothesized approach/avoidance and control/dyscontrol would characterize the dimensional structure of TRE and that dimensions would correlate with age, gender, and early life experiences. The present study developed a multidimensional model...

LONGITUDINAL DESCRIPTIVE PROFILE OF COLLEGIATE PITCHERS PARTICIPATING IN A SUMMER BASEBALL LEAGUE

Isabelle Leslie Gillis
The purpose of this study was to provide a longitudinal profile of pitching performance in a cohort of pitchers over two collegiate seasons and a summer league. Thus, this study utilized a longitudinal design to evaluate the impact of summer league participation on subsequent collegiate regular season pitching performance. Specifically, the performance of a cohort of Division 1 collegiate baseball pitchers during the 2018 Spring collegiate season, 2018 Summer League season, and the 2019 Spring...

Optimal Gateway Placement in Low-cost Smart Cities

Oluwashina Madamori
Rapid urbanization burdens city infrastructure and creates the need for local governments to maximize the usage of resources to serve its citizens. Smart city projects aim to alleviate the urbanization problem by deploying a vast amount of Internet-of-things (IoT) devices to monitor and manage environmental conditions and infrastructure. However, smart city projects can be extremely expensive to deploy and manage partly due to the cost of providing Internet connectivity via 5G or WiFi to IoT...

THE UTILIZATION OF TECHNOLOGY AS AN APPROACH TO IMPROVE MEAL PLANNING AND DIETARY INTAKE

Alexa Lauren Kuziel
The prevalence of obesity is rising in the United States and one factor that contributes to it is the lack of cooking at home and planning out meals. Since text messaging is now a main avenue of communication, it could be used to motivate people to plan out their meals and cook at home instead of consuming fast food. Current research on how weekly nudges might relate to peoples’ goals about meal preparation and dietary...

THE MODERATING ROLE OF MINDFULNESS SKILLS IN THE RELATIONSHIP BETWEEN BORDERLINE PERSONALITY FEATURES AND ASSOCIATED PROBLEMATIC BEHAVIORS

Carolina Caldera
Individuals with borderline personality disorder (BPD) experience intense affect and emotional dyscontrol that may lead them to engage in maladaptive coping strategies and behaviors such as substance use, alcohol use, risky sexual behavior, aggression, and emotional eating. Theory posits that mindfulness, a mental state in which one is attentive, aware, and accepting of the present moment, may lead to increased tolerance of emotional distress. The present study sought to investigate the role of dispositional mindfulness...

Identification of Bridges with Fracture-Prone Details

Theodore, II Hopwood, Rick Younce & Sudhir Palle
Welded steel girder bridges can contain details that can high welding and service stresses and are termed constraintinduced fractures (CIF). The Kentucky Transportation Cabinet has steel bridges with weld details known to cause CIFs whose girders have experienced fracture events. The Cabinet’s bridge inventory was reviewed and additional candidate bridges with potential CIF details were identified. A review of bridge plans and pictures along with followup field investigations pinpointed bridges with CIF details that warrant...

IMPROVING BICYCLE INFRASTRUCTURE WITH THE USE OF BICYCLE SHARE TRAVEL DATA

Jennifer Mintao Weast
Bicycling as a mode of transportation has been increasing in recent years due to its environmental and health benefits. The availability of bicycles through bicycle share programs has made bicycling a more viable option. With this increase, there is a need for complementary improvements of bicycle infrastructure. Many local and regional transportation agencies are recognizing this need and developing a master plan or safety action plan to improve the city’s bicycle and walking facilities. This...

THE IMPACT OF MATERNAL NUTRITION DURING PREGNANCY ON INFLAMMATION AND BIRTH OUTCOMES

Lori Ogden
More than 85% of American adults do not consume recommended amounts of fruits or vegetables. Preterm birth and hypertensive disorders of pregnancy are common adverse conditions affecting pregnancy and are leading causes of maternal and fetal morbidity and mortality. Preterm birth affects nearly 10% of all births in the United States and is on the rise, as are hypertensive disorders, which have increased by 25% over the last two decades. Pregnancy is a state of...

CDL Data Quality Assessment

Valerie Keathley-Helil, Mallory Brown, Andrew Martin, Amir E. Najarzadeh, Brian K. Howell & Jennifer R. Walton
Quality issues related to commercial driver license (CDL) data present ongoing challenges to state and federal transportation agencies. This study highlights several problems with CDL data, including a lack of standardization for state-specific traffic infractions; process and workflow difficulties that degrade the accuracy, validity, and timeliness of data; adjudication procedures that can potentially mask serious violations from CDL driver history records; inadequate recordkeeping in state law enforcement citation and court case management software applications; outdated...

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