554 Works

Determining Material Structures and Surface Chemistry by Genetic Algorithms and Quantum Chemical Simulations

Josiah Roberts
With the advent of modern computing, the use of simulation in chemistry has become just as important as experiment. Simulations were originally only applicable to small molecules, but modern techniques, such as density functional theory (DFT) allow extension to materials science. While there are many valuable techniques for synthesis and characterization in chemistry laboratories, there are far more materials possible than can be synthesized, each with an entire host of surfaces. This wealth of chemical...

THE EFFECTS OF A STRENGTHS BASED FACULTY COACHING INTERVENTION ON FIRST-YEAR UNDERGRADUATE STUDENT ACADEMIC CONFIDENCE

Conrad Davies
Deficiency remediation models of education imply that students may enter the university with deficiencies, problems, or needs that imply the student needs to be “fixed” before they can proceed in their academic studies. In contrast, strengths-based education models infer that students come to the university with inherent talents, natural propensities, and behaviors that can be leveraged to overcome their challenges. These differing perspectives can influence the effectiveness of university policies designed to improve student retention....

A QUALITATIVE EXAMINATION OF THE AGENCY OF WOMEN IN THEIR 30S AND 40S WHO USE DATING APPLICATIONS

Tera Buerkle
The use of dating applications (apps) to find romantic and sexual partners is widespread across age groups, however, there is a paucity of research on dating apps with those in middle adulthood. Sexual script theory suggests that women’s agency (i.e. the ability to act in one’s own best interest) may be impacted by expectations from an inherently sexualized context, such as dating apps. Feminist theory contends that women’s agency is complicated by gender socialization due...

ABC TRANSPORTERS IN GLIOBLASTOMA

Julia Schulz
Glioblastoma is one of the deadliest cancers, with a median survival of only one year. Even after aggressive treatment consisting of surgical resection, radiation, and chemotherapy, most glioblastoma patients suffer from tumor recurrence within 6-9 months. One reason for treatment failure of anticancer drugs is the blood-brain barrier that protects the brain by impeding xenobiotic uptake from the blood. To this end, efflux transporters at the human blood-brain barrier, such as P-glycoprotein (ABCB1) and Breast...

THE POTENTIAL ROLE OF TRAUMA-INFORMED POSITIVE EDUCATION IN THE SECONDARY MATHEMATICS CLASSROOM IN DISRUPTING THE PRESCHOOL-TO-PRISON PIPELINE

Jessica Michele Doering
This mixed-methods study considered the potential for trauma-informed mathematics education to disrupt the preschool-to-prison (or school-to-prison) pipeline. Phenomenological qualitative interviews were conducted in conjunction with the use of the Attitudes Related to Trauma-Informed Care (ARTIC; Baker et al., 2016) scale to determine teacher perceptions of trauma-informed care practices, their thoughts regarding challenging classroom behaviors and the connection of these behaviors with trauma and the pipeline, and their ideas about how much of an impact teachers...

Faculty Perceptions of Accreditation in the Field of Educator Preparation

Lauren Bell Graves
Accreditation is a measure the federal government, states, and other stakeholders utilize to determine the quality of an institution or a program. Educator preparation providers in Kentucky are required to obtain programmatic accreditation to offer educator preparation programs leading to certification or licensure. The Council for the Accreditation of Educator Preparation (CAEP) is the national accrediting body with which Kentucky has an agreement for joint programmatic accreditation. The Kentucky Education Professional Standards Board (EPSB) adopted...

INTERACTIONS OF POST-PKS ENZYMES OF THE MITHRAMYCIN BIOSYNTHETIC PATHWAY

Ryan Wheeler
Combinatorial biosynthesis is a powerful tool for generating new, more active drug analogues to combat disease. But in order for combinatorial biosynthesis to be employed to its full potential, a deep understanding of the enzymes that produce the parent molecule must be had. The goals of the work presented in this thesis are to characterize the reaction catalyzed by MtmW, the final enzyme in the mithramycin (MTM) biosynthetic pathway, and to discover the interaction between...

RISK FACTORS FOR WORKPLACE SEXUAL HARASSMENT IN FEMALE TRUCK DRIVERS

Kimberly Riddle
Sexual harassment is one of the most common forms of workplace violence in the United States. Sexual harassment is defined as unwanted verbal and physical behaviors of a sexual nature (e.g., physical advances, requests for sexual favors, inappropriate sexist or sexual comments or jokes, pornography, or other unwanted conduct) that creates an uncomfortable working environment or interferes with the employee’s job responsibilities. In general, it is estimated that nearly one in every two women have...

RATE TO MEASURE MATHEMATICS TEACHING: USING THE MANY-FACET RASCH MODELING TO REEVALUATE THE MATHEMATICS CLASSROOM OBSERVATION PROTOCOL FOR PRACTICES (MCOP2)

Chunling Niu
Rater-mediated classroom observation protocols are increasingly being used for teaching performance assessments, which makes identifying and controlling for various rater effects a central issue to ensure the rating quality. A series of validation studies under the classical test theory framework, including content validity, interrater reliability, and structure analysis, have been completed for the 16-item Mathematics Classroom Observation Protocol for Practices (MCOP2). However, the MCOP2 data have never been investigated under the Rasch framework. Due to...

INCORPORATION OF SUMMER ANNUAL MIXTURES INTO GRAZING SYSTEMS IN KENTUCKY

Kelly Mercier
Utilizing summer annual grass-legume forage mixtures has the potential to improve forage yield and nutritive characteristics, and/or animal performance during times when cool-season pasture growth is limited by high temperatures. Legumes can utilize atmospheric nitrogen, which can increase crude protein and forage digestibility in mixtures. As nitrogen application generally improves both the yield and nutritive characteristics of summer annual forages, but can have a negative effect on legume competitiveness, nitrogen fertilizer recommendations for legume-containing summer...

DEVELOPMENT OF NOVEL POLYMERIC MATERIALS FOR THEIR APPLICATION IN MONITORING AND REMEDIATION OF ENVIRONMENTAL POLLUTANTS

Rishabh Shah
Remediation of environmental pollutants from water is one of the major challenges in the 21st century. Utilizing novel polymeric materials to accomplish this challenge has garnered a lot of interest in recent times. Flexibility in synthesizing as well as functionalizing makes them attractive for their application in pollutant remediation. This work is based on development and characterization of novel crosslinked polymeric as well as linear polymeric materials from biphenyl-based monomers, biphenyl based crosslinker and a...

The Effects of Systematic Manipulation of Reinforcement Within a Classroom Management System

Amanda Gayle Chavez
Research suggests that best practice is for teachers to incorporate evidence-based classroom management strategies into their daily routines to improve student behavior. One aspect crucial to evidence-based practices is the rate at which teachers deliver reinforcement. Though research recommends reinforcement be provided frequently within classroom management systems (Robacker et al., 2016), no objective recommendation exists that assists teachers in delivering it systematically. In this study, a single case withdrawal design was used to analyze the...

RESIDUAL SPATIAL AUTOCORRELATION IN MACROECOLOGICAL AND BIOGEOGRAPHICAL MODELING

Guetchine Gaspard
Macroecological and biogeographical modelers have predicted the distribution of species across space relying on the relationship between biotic processes and environmental variables. Such a method employs data associated, for instance, with species abundance or presence/absence, climate, geomorphology, and soils. Statistical analyses found in previous studies have highlighted the importance of accounting for the effects of spatial autocorrelation (SAC), which indicates a level of dependence between pairs of nearby observations. A consensus has existed that residual...

INTEGRATING PERSUASIVE MESSAGING STRATEGIES INTO HIGHER EDUCATION EARLY ALERT INTERVENTIONS TO IMPROVE STUDENT ACADEMIC BEHAVIORS

Joseph Gayheart
Higher Education is at a critical juncture as both public and private institutions seek to attract, retain, and graduate students. Institutions of higher education have traditionally developed communication and engagement strategies that become part of early warning/alert systems intended to increase student positive academic behaviors and improve student success. Persuasion can be a powerful tool in improving communication—especially when persuasive messages are deployed within the complex and ever-changing media landscape. Communication and persuasion scholars, for...

Utilizing a Theory of Change Process to Establish Framework for a Student Success Course

Sy Bridenbaugh
The student success course has become a staple of the college experience. As the academic and social environment continues to shift with each new incoming cohort, having a designed and evaluated framework to utilize during student success course development can be a useful tool. Research surrounding student success in college is abundant. Having a framework that draws on this research for setting learning objectives and determining high impact practices for a student success course could...

ClpXP Degradation System in Escherichia coli, a Study of Its Energy Sources and Its Applications in Managing the Expression Levels of Targeted Membrane and Soluble Proteins

Thilini Abeywansha
ClpXP is an Escherichia coli protease that carries out energy-dependent intracellular proteolysis. In recent years, this system has been widely studied due to its importance as protein regulatory machinery and a virulence factor. Protein substrates of ClpXP contain degrons with a specific protein sequence. SsrA tag is one of the five degrons known to designate proteins for ClpXP degradation. SsrA is an 11 amino acid peptide added to the C-terminus of nascent polypeptide chains translated...

REMOTE SUPPORTED COMMUNICATION FOR ADULTS WITH CHRONIC APHASIA

Allie Hopper
Supported communication is defined as anything that improves access to or participation in communication events or activities (King, Simmons-Mackie, & Beukelman, 2012). This thesis describes the results of a study that took place when a training program to provide graduate students in Communication Sciences and Disorders (CSD) with “hands on” experience in providing supported communication to persons with chronic aphasia (PWA) was interrupted by the outbreak of Coronavirus-19 and switched to a remote delivery format...

Synthesis of Dual Small Molecule Hybrids to Probe the Synergy between DNA Repair Enzymes and IDO1

Nathaniel George
Indoleamine 2 3-dioxygenase (IDO) has recently been highlighted as a promising target for small molecule based immunotherapy. IDO is often coopted by various cancer cells to promote an immune-suppressive environment around tumors. DNA damage repair (DDR) enzymes have recently been targeted for inhibition to promote genetic instability and bolster immune recognition. DDR enzymes such as PARP and POLγ are common inhibition targets due to their direct effects on cellular function. In the process of designing...

To “Reawaken The Conscience of Mankind”

Cody Foster
This dissertation looks at the International War Crimes Tribunal (IWCT) as a vessel for human rights’ ideas during the Vietnam War. I argue that the IWCT supported a transnational advocacy network that used the language of human rights to oppose the Vietnam War and rally support from those around the world who stood against American imperialism. On the one hand, the tribunal precedes the institutionalization of human rights in the 1970s. On the other, it...

A Tropical Approach to the Brill-Noether Theory Over Hurwitz Spaces

Kaelin Cook-Powell
The geometry of a curve can be analyzed in many ways. One way of doing this is to study the set of all divisors on a curve of prescribed rank and degree, known as a Brill-Noether variety. A sequence of results, starting in the 1980s, answered several fundamental questions about these varieties for general curves. However, many of these questions are still unanswered if we restrict to special families of curves. This dissertation has three...

SONGS FOR HIGH VOICE

Makeda Hampton
African Romances, Op. 17, composed in 1897 by African-British composer Samuel Coleridge-Taylor (1875-1912), is a collection of seven songs for high voice that is uniquely both African and American. The lyrics of this song cycle were first published in the book Majors and Minors, a collection of poems published in 1895 by Paul Laurence Dunbar (1872-1906). An analysis of resources supports that academic discourse in Black vocal music has been underrepresented due to the absence...

Weight Distributions, Automorphisms, and Isometries of Cyclic Orbit Codes

Hunter Lehmann
Cyclic orbit codes are subspace codes generated by the action of the Singer subgroup Fqn* on an Fq-subspace U of Fqn. The weight distribution of a code is the vector whose ith entry is the number of codewords with distance i to a fixed reference space in the code. My dissertation investigates the structure of the weight distribution for cyclic orbit codes. We show that for full-length orbit codes with maximal possible distance the weight...

Combining Approximate Computing And Adiabatic Logic For Low-Power And Energy-Efficient Iot Edge Computing

Wu Yang
The growing data-intensive applications that run on IoT edge devices require the circuit to be low-power consumption and energy-efficient for limited resources. As conventional Complementary Metal-Oxide-Semiconductor (CMOS) scales down to the nanometer technology node, it reaches its limits, such as leakage and power consumption. Adiabatic logic and approximate computing are emerging techniques for the low-power circuit. Adiabatic logic can recycle energy which is a promising solution for building energy-efficient circuits. However, the power clock scheme...

Real-World Applications for Analytics Teaching and Learning

Anita Lee-Post
This document provides learning-by-doing materials for Analytics software skill development using SAS JMP. It integrates Analytics concepts and techniques with real-world scenarios based on the COVID-19 pandemic to illustrate how real-world data can be transformed into actionable insights to offer decision support for COVID-19 related issues. A holistic treatment of the Analytics process from data acquisition and cleansing to data analysis and interpretation is emphasized using five studies: 1. Characterize COVID-19 mortality demographic risk factors,...

USGS 104(b) Grant Program

Emily Koyagi, Steve Evans & Lindell Ormsbee
The Kentucky Water Resources Research Institute (KWRRI) is one of 54 federally authorized water resource institutes or centers throughout the United States and its territories. It operates under the authority of the Water Resources Research Act of 1964 (P.L. 88-379 codified at 42 U.S.C. 10301 et seq.) through the Water Resources Research Institutes Program administered by the United States Geological Survey (USGS). KWRRI’s annual base grant program under section 104(b) supports the following objectives specified...

Registration Year

  • 2021
    554

Resource Types

  • Dissertation
    295
  • Text
    198
  • Dataset
    29
  • Report
    22
  • Journal Article
    5
  • Data Paper
    3
  • Book
    1
  • Conference Proceeding
    1

Affiliations

  • University of Kentucky
    554
  • Zhejiang University
    14
  • Sun Yat-sen University
    11
  • Xiamen University
    11
  • Sichuan University
    10
  • State Administration of Traditional Chinese Medicine of the People's Republic of China
    9
  • Chinese Academy of Tropical Agricultural Sciences
    9
  • Wenzhou Medical University
    9
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    9
  • Hebei Normal University
    8