546 Works

A COMPARATIVE STUDY OF STRESS, TRAUMA, WELL-BEING, AND FUTURE ORIENTATION AMONG COMMUNITY COLLEGE STUDENTS

Melinda LeMaster
This study measured perceived stress, past trauma, well-being, and future orientation in a sample of community college students located in the Southeast United States. The sample included 412 participants (78%) female; 59% of student participants reported living in a rural community and 41% in a non-rural community. The mean age was 22 for 70% of participants, while 30% were over age 30. Framed by Family Stress Theory and Human Ecological Systems Theory, the study tested...

FIRST-GENERATION DOCTORAL STUDENTS’ EXPERIENCES NAVIGATING GRADUATE SCHOOL

Leah Vance-Berg
First-generation students who pursue graduate programs face a unique set of challenges and rely on their strengths to help them navigate their graduate programs. This study will look at how first-generation students have navigated their graduate course work. Semi-structured interviews were conducted with 19 doctoral students at Magnolia University where participants discussed the challenges they have faced during graduate school and how they have navigated these challenges. This exploratory study uses social and cultural capital...

SCIENCE-BASED REGULATION OF PHARMACOLOGICAL SUBSTANCES IN COMPETITION HORSES

Jacob Machin
Current testing methodologies within equine forensic toxicology focus on arbitrary thresholds and zero-tolerance policy. Modern analytical chemistry’s limits of detection are low enough that oftentimes femtogram-per-milliliter amounts of a substance can readily be identified in both blood and urine of a horse. For most pharmacologically relevant compounds, these concentrations have no relevance to pharmacological effect. It is therefore crucial that testing methodologies to determine appropriate thresholds and cut-offs be developed that are driven by biological...

QUANTIFICATION OF IN-PLAY COMPETITION DEMANDS OF COLLEGIATE AMERICAN FOOTBALL PLAYERS USING GLOBAL POSITIONING SYSTEMS

Alex Brownell
There is limited information describing the competition demands of American football. A greater understanding of competition demands will allow strength and conditioning practitioners to create appropriate training programs to enhance athlete readiness and performance. Therefore, the purpose of this study was to analyze the competition demands of collegiate American football players using global positioning systems (GPS), specifically comparing the in-play GPS versus out-of-play GPS outcomes. Twenty-two American football athletes (Age: 20.8 ± 0.9 yr, Height:...

COMPARATIVE EFFECTS OF WORDS PLUS PICTURES AND WORDS ALONE ON THE READING COMPREHENSION OF YOUTH WITH DISABILITIES

Lindsay Caudill
This study compared the effectiveness and efficiency of two instructional conditions on the reading comprehension of fifth and sixth grade students with moderate and severe disabilities. A words plus pictures and words alone condition were examined through the use of an adapted alternating treatment design replicated across 3 participants. Results indicated that the effect was minimal, with words plus pictures being slightly more effective.

Weakly Supervised Learning for Multi-Image Synthesis

Muhammad Usman Rafique
Machine learning-based approaches have been achieving state-of-the-art results on many computer vision tasks. While deep learning and convolutional networks have been incredibly popular, these approaches come at the expense of huge amounts of labeled data required for training. Manually annotating large amounts of data, often millions of images in a single dataset, is costly and time consuming. To deal with the problem of data annotation, the research community has been exploring approaches that require less...

AN ASSESSMENT OF THE CARRIER STATE AND A NOVEL MARKER OF LEPTOSPIRA AND ABORTION IN CENTRAL KENTUCKY HORSES

Gloria Gellin
Leptospirosis is a reemerging zoonotic infection of worldwide importance and affects all mammals. The bacterium is transmitted to animals and humans by urine, fetal membranes and body fluids. Leptospira shedding in the urine contaminates both soil and water, exposing both humans and animals to the bacterium. Leptospirosis in horses can cause abortion and is one of the etiologies of equine recurrent uveitis which can lead to blindness. Equine leptospiral abortion in Central Kentucky is primarily...

Myelin, cPLA2, and Azithromycin

Timothy Kopper
Spinal cord injury (SCI) produces a chronic inflammatory state primarily mediated by macrophages consisting of resident microglia and infiltrating monocytes. These chronically activated SCI macrophages adopt a pro-inflammatory, pathological state that continues to cause additional damage after the initial injury and inhibits recovery. While the roles of macrophages in SCI pathophysiology are well documented, the factors contributing to this maladaptive response are poorly understood. Here, we identify the detrimental effects of myelin debris on macrophage...

Kentucky Traffic Collision Facts 2020

Eric Green, Paul Ross, Christopher Blackden, Michael Fields & Kenneth Agent
KENTUCKY’S TRAFFIC COLLISION FACTS report is based on collision reports submitted to the Kentucky State Police Records Branch. As required by Kentucky Revised Statutes 189.635: “Every law enforcement agency whose officers investigate a vehicle accident of which a report must be made...shall file a report of the accident...within ten days after investigation of the accident upon forms supplied by the bureau.” The stated purpose of this requirement is to utilize data on traffic collisions for...

Revisiting Absolute Pose Regression

Hunter Blanton
Images provide direct evidence for the position and orientation of the camera in space, known as camera pose. Traditionally, the problem of estimating the camera pose requires reference data for determining image correspondence and leveraging geometric relationships between features in the image. Recent advances in deep learning have led to a new class of methods that regress the pose directly from a single image. This thesis proposes methods for absolute camera pose regression. Absolute pose...

Evaluation of the Kentucky Transportation Cabinet’s Maintenance Rating Program

Bryan Gibson, Rachel Catchings, Vinh Dao & Doug Kreis
The Kentucky Transportation Cabinet (KYTC) relies on its Maintenance Rating Program (MRP) to systematically measure conditions on state-owned roads and rights of way. Every year, the Cabinet evaluates 300-400 road segments in each of its highway districts. Segments receive aggregate scores ranging from 0 to 100, with the target score being 80. This report appraises the MRP and discusses potential strategies for its improvement. Compared to asset management programs established at other state transportation agencies,...

COMPUTATIONAL INSIGHTS ON MEDICINAL CHEMISTRY TARGETING CYP450s

Alexander Fenton
Modern-day medicinal chemistry has provided researchers with a wide variety of tools to not only gather greater insight from their data, but also to generate data in new ways. One such tool is the construction of computational protein models from crystallographic datasets, and their subsequent use to understand the structure-activity relationships of protein-ligand complexes. These models can be utilized for their predictive power to inform the synthesis of, and improvement of, lead compounds. It is...

THE EFFECTS OF FORM OF SELENIUM ON THE BOVINE CORPUS LUTEUM, UTERINE ENDOMETRIUM, AND DEVELOPMENT OF THE CONCEPTUS

Benjamin Ryne Crites
Widespread regions of the southeast United States have soils deficient in selenium (Se), necessitating Se supplementation to cattle grazing in these areas. Adequate dietary Se is required for optimal immune function, growth, and fertility. In forages, Se is predominantly found in the organic form (OSe), which is known to increase bioavailability. However, the inorganic form (ISe) is typically found in commercial mineral mixes. We previously reported that supplementation with an isomolar 1:1 mix (MIX) of...

Epidemiology of Upper Extremity Injuries in High School Sports

Autumn Ruthe Whitson
Participation in high school sports has seen a steady increase over the past four decades. With nearly eight million student-athletes participating, careful monitoring of injuries related to their participation is imperative. Injury surveillance efforts through national databases have produced a multitude of studies detailing injuries that occur in specific sports, specific body parts, or particular diagnoses. The lower extremity tends to be injured more frequently than the upper extremity resulting in various comprehensive analyses on...

TECHNOLOGY LEADERSHIP PRACTICES OF APPALACHIAN SCHOOL LEADERS DURING THE COVID-19 PANDEMIC

Todd Norton
The COVD-19 pandemic caused a global disruption to education. In some parts of the United States, schools were cancelled for the year, while others shifted their educational offerings to a distance learning model. Kentucky announced short term closures beginning March 13, 2020, but on April 20th the Kentucky Governor announced that schools would not reopen for in-person instruction for the remainder of the academic year. Many school districts quickly developed a plan to continue a...

Re-designing Main Memory Subsystems with Emerging Monolithic 3D (M3D) Integration and Phase Change Memory Technologies

Chao-Hsuan Huang
Over the past two decades, Dynamic Random-Access Memory (DRAM) has emerged as the dominant technology for implementing the main memory subsystems of all types of computing systems. However, inferring from several recent trends, computer architects in both the industry and academia have widely accepted that the density (memory capacity per chip area) and latency of DRAM based main memory subsystems cannot sufficiently scale in the future to meet the requirements of future data-centric workloads related...

WORKPLACE LACTATION SUPPORT AND BREASTFEEDING PRACTICES IN EMPLOYED MOTHERS

Robin Ray
Low rates of breastfeeding are a global public health issue. Despite national and international health agency recommendations for breastfeeding until infants are six months of age when solid foods are introduced and continued breastfeeding until 12 months of age or older, many mothers in the United States discontinue breastfeeding at an early age. Return to work after childbirth is one of the leading contributing factors to early cessation of breastfeeding in employed mothers. Understanding the...

Special Power Electronics Converters and Machine Drives with Wide Band-Gap Devices

Yibin Zhang
Power electronic converters play a key role in power generation, storage, and consumption. The major portion of power losses in the converters is dissipated in the semiconductor switching devices. In recent years, new power semiconductors based on wide band-gap (WBG) devices have been increasingly developed and employed in terms of promising merits including the lower on-state resistance, lower turn-on/off energy, higher capable switching frequency, higher temperature tolerance than conventional Si devices. However, WBG devices also...

“I’m Like Their GPS”

Bonita Tyler
As American community colleges replace prerequisite developmental mathematics courses with corequisite courses, the work of faculty to support underprepared students merits attention. This curricular change means underprepared students are enrolling directly in both college-level content courses with required corequisite support courses for necessary remediation, thus broadening the range of student skills and abilities in the classroom. Faculty work is significantly impacted by this change. Previous research indicates that corequisite course configurations have mitigated some problems...

Identification of downstream targets and signaling pathways of long non-coding RNA NR_002794 in human trophoblast cells

Yinyao Ma, Hua Wu, Xuxia Liang, Chun Zhang, Yanhua Ma, Yanfen Wei, Jing Li & Hui Chen
Preeclampsia (PE) is a huge threat to pregnant women. Our previous study demonstrated that long non-coding RNA (lncRNA) NR_002794 was highly expressed in placentas of PE patients and could regulate the phenotypes of trophoblast cells. However, the downstream regulatory mechanisms of NR_002794 remain unknown. In this text, some potential downstream targets or signaling pathways of NR_002794 were identified through RNA sequencing (RNA-seq) and bioinformatics analysis in SWAN71 trophoblast cells. Western blot assay demonstrated that NR_002794...

Discovery of novel serum metabolic biomarkers in patients with polycystic ovarian syndrome and premature ovarian failure

Jiying Chen, Qinger Zhou, Yonggang Zhang, Wenqing Tan, Hanchao Gao, Liying Zhou, Shuixiu Xiao, Jinhua Gao, Jing Li & Zhiying Zhu
Several widely recognized metabolites play a role in regulating the pathophysiological processes of various disorders. Nonetheless, the lack of effective biomarkers for the early diagnosis of polycystic ovarian syndrome (PCOS) and premature ovarian failure (POF) has led to the discovery of serum-based metabolic biomarkers for these disorders. We aimed to identify various differentially expressed metabolites (DEMs) through serum-based metabolic profiling in patients with PCOS and POF and in healthy individuals by using liquid chromatography–mass spectrometry...

Registration Year

  • 2021
    546

Resource Types

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    192
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    22
  • Journal Article
    5
  • Data Paper
    3
  • Book
    1
  • Conference Proceeding
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Affiliations

  • University of Kentucky
    546
  • Zhejiang University
    8
  • Sun Yat-sen University
    7
  • Wenzhou Medical University
    6
  • Shanghai University of Traditional Chinese Medicine
    6
  • Guangzhou Medical University
    6
  • State Administration of Traditional Chinese Medicine of the People's Republic of China
    5
  • Chinese Academy of Tropical Agricultural Sciences
    5
  • Hebei Normal University
    5
  • North West Agriculture and Forestry University
    5