27 Works

Data from: Abnormal CSF amyloid-β42 and tau levels in hip fracture patients without dementia

Esther S. Oh, Kaj Blennow, George E. Bigelow, Sharon K. Inouye, Edward R. Marcantonio, Karin J. Neufeld, Paul B. Rosenberg, Juan C. Troncoso, Nae-Yuh Wang, Henrik Zetterberg, Frederick Sieber, Constantine G. Lyketsos & Frederick E. Sieber
Background: There is strong association of Alzheimer's disease (AD) pathology with gait disorder and falls in older adults without dementia. The goal of the study was to examine the prevalence and severity of AD pathology in older adults without dementia who fall and sustain hip fracture. Methods: Cerebrospinal fluid (CSF) was obtained from 168 hip fracture patients. CSF Aβ42/40 ratio, p-tau, and t-tau measures were dichotomized into normal vs. abnormal, and categorized according to the...

Data from: Factors associated with pulmonary impairment in HIV-infected South African adults

Akshay N. Gupte, Michelle L. Wong, Reginah Masandiwa, Grace L. Barnes, Jonathan Golub, Richard E. Chaisson, Christopher J. Hoffmann, Neil A. Martinson & Reginah Msandiwa
Background: HIV-infected individuals have increased risk of developing obstructive lung disease (OLD). Studies from developed countries report high viral load, low CD4 counts, and anti-retroviral therapy (ART) to be associated with OLD; but these findings may not be generalizable to populations in resource-limited settings. Methods: We conducted a prospective cohort study of lung function in 730 HIV-infected black South African adults. Pre-bronchodilator spirometry was performed at enrollment and repeated annually for three years. Logistic regression...

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