This prospective study will test whether markers of self-regulation are associated with protective effects against negative impacts to mental health, well-being, and substance use in response to the COVID-19 pandemic.
Machiavellianism demonstrates divergent associations with social status, aggression and empathy (e.g., Berger, Batanova, & Cance, 2015). Specifically, the potential for high Machiavellians who perceive themselves as being low in status may be more likely to rely on aggressive tactics to achieve their goals than those who have greater social capital (i.e., status). As such, we are interested in examining the potential for such clusters emerge between trait Machiavellianism and social status. In order to examine...
FSCI 2021 course T18, Unpacking the Role of Preprints in Scholarly Inclusion
This research will document prevalence of racial bias (implicit/explicit prejudice and implicit/explicit stereotypes) among genetic counselors and trainees.
Uncovering antiobesity-related hypertension targets and mechanisms of metformin, an antidiabetic medicationLu Yang, Jianxin Yang, Xiao Liang, Wenjun Huang, Xiaoxi Zhang & Rong Li
Metformin, a common clinical drug used to treat diabetes mellitus, is found with potential antiobese actions as reported in increasing evidences. However, the detailed mechanisms of metformin-antiobesity-related hypertension remain unrevealed. We have utilized the bioinformatics strategy, including network pharmacology and molecular docking analyses, to uncover pharmacological targets and molecular pathways of bioactive compounds against clinical disorders, such as cancers, coronavirus disease 2019. In this report, the in-silico approaches using network pharmacology and molecular docking was...
The proposed study will clarify the contribution of anxiety sensitivity to the comorbidity of anxiety and weight related distress in adolescence. The project has multiple, sequential aims. First, we will estimate the genetic, shared environmental and unique environmental contributions to a latent composite of weight related distress indexed by four items from the Eating Disorder Diagnostic Scale (EDDS). We will compare this common factor model to a correlated factors model, which estimates correlated genetic and...
In Many Labs 2, we will employ an expanded version of the Many Labs paradigm to investigate a substantial number of new effects and further examine the findings from Many Labs 1.
Defining the Heart of Darkness: A Psychometric and Behavioral Analysis of the Relationship Between Psychopathy and SadismEmily Lasko & David Chester
Psychopathy and sadism, personality constructs largely characterized by antagonistic tendencies, share several similar traits and behaviors such as cruelty, callousness, and antisocial behavior (Foulkes, 2019; Hare, 2003). They are two of the most severe risk factors for criminal offending and aggression across a wide range of contexts, rendering these traits major public health concerns (Foulkes, 2019; Kiehl & Hoffman, 2011; Reidy et al., 2015). Despite the risks they pose, these constructs are relatively poorly understood....
The initial lockdown phase of the COVID-19 pandemic presented an unfortunate opportunity to observe how abrupt, large-scale changes in traffic volume can reduce greenhouse gas emissions. This study explores how carbon dioxide (CO2) emissions from Virginia’s transportation sector may have been affected by the changes in activity stemming from COVID-19 to inform more carbon-neutral policies as the state recovers from the economic downfall. Emission savings were calculated by multiplying the percent change from 2019 to...
Adverse Childhood Experiences in a Diverse Sample of Undergraduates: Potential Relationship to Age of Initiation and EthnicityChelsea Crayton, Amy Adkins & Tegwyn Brickhouse
Adverse childhood experiences have repeatedly been shown to be associated with poor long-term physical, mental, and oral health outcomes. This has in some parts been attributed to an increased risk of engaging in risky health behaviors. For incoming college students with previous adverse childhood experiences, this risk is amplified by the pressure to engage in risky health behaviors that are now intertwined in the traditional college experience. However, current research has yet to examine the...
High-Grade Serous Ovarian Cancer and Serous Tubal Intra-epithelial Carcinoma Effect on Survial after Surgical and Platinum Chemotherapeutic TreatmentMaria Del Carmen Camarena, Dana Lapato & Walker Rogers
HGEN 611 Fall 2021
We are researching how social exclusion among African American college students in the form of racism and discrimination influence depressive symptoms.
Alteration of long non-coding RNAs and mRNAs expression profiles by compound heterozygous ASXL3 mutations in the mouse brainSonghui Zhang, Fang Fu, Li Zhen, Ru Li & Can Liao
Compound mutations in the additional sex combs-like 3 (ASXL3) gene greatly impact the expression of long non-coding RNAs (lncRNAs) and messenger RNAs (mRNAs) in mouse myocardial tissues. Little is known about ASXL3 mutation effects on lncRNAs and mRNAs expression in the cerebrum and cerebellum. This study aims to clarify this point using quantitative real-time polymerase chain reaction and Western blotting. Transcriptome analysis based on RNA-seq followed by bioinformatics analysis were used to compare lncRNA and...
Marijuana use is often started in college and with the expansion of legalization more college students may have access to it in the future so it is important to understand how this might affect a common mental health problem.
Revenge is associated with reward and positive affect (Chester, 2017), but the details of how these feelings unfold over time are unclear. More specifically, it is unclear if people experience positive affect prior to revenge, during revenge, and/or after revenge. Further, it is unknown the extent to which these various experiences of revenge-related affect differ among people with antagonistic personality traits (e.g., psychopathy, sadism, machiavellianism, narcissism).
Virginia Commonwealth University584
Shanghai Jiao Tong University115
Chinese Academy of Sciences85
Southern Medical University80
Chinese Academy of Medical Sciences & Peking Union Medical College67