4 Works

Data from: Predictors of alcohol responsiveness in dystonia

Johanna Junker, Valerie Brandt, Brian D. Berman, Marie Vidailhet, Emmanuel Roze, Anne Weissbach, Cynthia Comella, Irene A. Malaty, Joseph Jankovic, Mark S. LeDoux, Alfredo Berardelli, Richard Barbano, Stephen G. Reich, Joel S. Perlmutter, Hyder A. Jinnah & Norbert Brüggemann
Objective: To determine predictors of alcohol responsiveness in a large cohort of dystonia patients. Methods: 2159 participants with dystonia were prospectively enrolled in the cross-sectional Dystonia Coalition multicenter study. Patients with secondary, combined or confirmed genetic dystonia (total n=164) or unknown alcohol responsiveness (n= 737) were excluded. Patients answered a standardized questionnaire and were clinically examined using a standardized video protocol and the Burke-Fahn-Marsden Dystonia Rating Scale. Alcohol responsiveness was determined by patients’ self-report. Results:...

Data from: Faster processing of moving compared to flashed bars in awake macaque V1 provides a neural correlate of the flash lag illusion

Manivannan Subramaniyan, Alexander S. Ecker, Saumil S. Patel, R. James Cotton, Matthias Bethge, Xaq Pitkow, Philipp Berens & Andreas S. Tolias
When the brain has determined the position of a moving object, due to anatomical and processing delays, the object will have already moved to a new location. Given the statistical regularities present in natural motion, the brain may have acquired compensatory mechanisms to minimize the mismatch between the perceived and the real position of moving objects. A well-known visual illusion — the flash lag effect — points towards such a possibility. Although many psychophysical models...

Data from: Genetic signatures of microbial altruism and cheating in social amoebas in the wild

Suegene Noh, Katherine S. Geist, Xiangjun Tian, Joan E. Strassmann & David C. Queller
Many microbes engage in social interactions. Some of these have come to play an important role in the study of cooperation and conflict, largely because, unlike most animals, they can be genetically manipulated and experimentally evolved. However, whereas animal social behavior can be observed and assessed in natural environments, microbes usually cannot, so we know little about microbial social adaptations in nature. This has led to some difficult-to-resolve controversies about social adaptation even for well-studied...

Data from: Impaired spatial memory codes in a mouse model of Rett syndrome

Sara E. Kee, Xiang Mou, Huda Y. Zoghbi & Daoyun Ji
The Mecp2+/-mouse model recapitulates many phenotypes of patients with Rett syndrome (RTT), including learning and memory deficits. It is unknown, however, how the disease state alters memory circuit functions in vivoin RTT mice. Here we recorded from hippocampal place cells, which are thought to encode spatial memories, in freely moving RTT mice and littermate controls. We found that place cells in RTT mice are impaired in their experience-dependent increase of spatial information. This impairment is...

Registration Year

  • 2018
    4

Resource Types

  • Dataset
    4

Affiliations

  • Baylor College of Medicine
    4
  • Washington University in St. Louis
    2
  • Howard Hughes Medical Institute
    1
  • Rice University
    1
  • University of Pennsylvania
    1
  • Assistance Publique -Hopitaux De Paris
    1
  • University of Maryland Medical Center
    1
  • University of Lübeck
    1
  • University of Rochester Medical Center
    1
  • Denver VA Medical Center
    1