Additional file 1. Supplementary Table 1: Values of EQ-5D-index and EQ-VAS by level of each independent categorical variable (reported by the levels of the ecological model).

Additional file 1. Supplementary Table 1: Values of EQ-5D-index and EQ-VAS by level of each independent categorical variable (reported by the levels of the ecological model).

Abstract Background The PROLOGUE score (PROgnostication using LOGistic regression model for Unselected adult cardiac arrest patients in the Early stages) is a novel prognostic model for the prediction of neurological outcome after cardiac arrest, which showed exceptional performance in the internal validation. The aim of this study is to validate the PROLOGUE score in an independent cohort of unselected adult cardiac arrest patients and to compare it to the thoroughly validated Out-of-Hospital Cardiac Arrest (OHCA)...

Additional file 1. Supplementary figures and tables

Abstract Background During the 2020/2021 winter, the labour market was under the impact of the COVID-19 pandemic. Changes in socioeconomic resources during this period could have influenced individual mental health. This association may have been mitigated or exacerbated by subjective risk perceptions, such as perceived risk of getting infected with SARS-CoV-2 or perception of the national economic situation. Therefore, we aimed to determine if changes in financial resources and employment situation during and after the...

Additional file 1: Table S1. Study population selection. Table S2. Exposure distributions. Table S3. Spearman correlations between exposures (top), and between exposures and neighbourhood socio-economic position (SEP) score (bottom). Table S4. Mean exposure by quintiles of neighbourhood socio-economic position. Table S5. Hazard ratios (95% confidence intervals) for single exposure associations between air pollution and noise exposures and mortality by cause, with increasing level of covariate adjustment in single exposure models. Table S6. Effect modification by...

Abstract Background High bed-occupancy (capacity utilization) rates are commonly thought to increase in-hospital mortality; however, little evidence supports a causal relationship between the two. This observational study aimed to assess three time-varying covariates—capacity utilization, patient turnover and clinical complexity level— and to estimate causal effect of time-varying high capacity utilization on 14 day in-hospital mortality. Methods This retrospective population-based analysis was based on routine administrative data (n = 1,152,506 inpatient cases) of 102 Swiss general...

Additional file 1: Table S1 Indicator weights generated by factor analysis for the individual years. Table S2 Missing values across indicators prior and after imputing based on similar profile. Figure S1 Percentage of mortality attributable to housing inequality by the HDI 1991, sex and age group in a period of 1991-2000. Figure S2 Percentage of mortality attributable to housing inequality by the HDI 2001, sex and age group in a period of 2001-2010. Figure S3...

Supplementary Material 2

Supplementary Material 4

Additional file 2: Supplementary Table 2. Reasons for exclusion of studies after reviewing the full texts against the eligibility criteria.

Abstract Background Implementation fidelity assesses the degree to which an intervention is delivered as it should be. Fidelity helps to determine if the outcome(s) of an intervention are attributed to the intervention itself or to a failure of its implementation. Little is known about how fidelity impacts the intended outcome(s) and what elements or moderators can affect the fidelity trajectory over time. We exemplify the meaning of implementation fidelity with INTERCARE, a nurse-led care model...

Supplementary Material 3

Additional file 9: Appendix S9. Clinical episodes recording form.

Abstract Background It has been more than 20 years since the malaria epidemiologic shift to school-aged children was noted. In the meantime, school-aged children (5–15 years) have become increasingly more vulnerable with asymptomatic malaria prevalence reaching up to 70%, making them reservoirs for subsequent transmission of malaria in the endemic communities. Intermittent Preventive Treatment of malaria in schoolchildren (IPTsc) has proven to be an effective tool to shrink this reservoir. As of 3rd June 2022,...

Abstract Background Cardiovascular diseases (CVDs), the leading cause of death worldwide, are sensitive to temperature. In light of the reported climate change trends, it is important to understand the burden of CVDs attributable to temperature, both hot and cold. The association between CVDs and temperature is region-specific, with relatively few studies focusing on low-and middle-income countries. This study investigates this association in Puducherry, a district in southern India lying on the Bay of Bengal, for...

Abstract Background Cardiovascular diseases (CVDs), the leading cause of death worldwide, are sensitive to temperature. In light of the reported climate change trends, it is important to understand the burden of CVDs attributable to temperature, both hot and cold. The association between CVDs and temperature is region-specific, with relatively few studies focusing on low-and middle-income countries. This study investigates this association in Puducherry, a district in southern India lying on the Bay of Bengal, for...

Additional file 1. Table S1. The results of volumetric measurement in the two groups. Table S2. Distribution of preoperative and postoperative membrane-bone cavity volume ratio (R) in the two groups.

Additional file 5: Genes associated to regulatory TE in sperm fractions sorted based on YOPRO.

Abstract Background Postpartum home-based midwifery care is covered by basic health insurance in Switzerland for all families with newborns but must be self-organized. To ensure access for all, Familystart, a network of self-employed midwives, launched a new care model in 2012 by ensuring the transition from hospital to home through cooperation with maternity hospitals in the Basel area. It has particularly improved the access to follow-up care for families in vulnerable situations needing support beyond...

Additional file 3. Clinical study protocol (main study).

Additional file 5. Clinical study protocol (SKIP Energy).

Additional file 6. Informed consent form (energy), informed consent form (fMRI), informed consent form (main study).

In settings with high tuberculosis (TB) endemicity, distinct genotypes of the Mycobacterium tuberculosis complex (MTBC) often differ in prevalence. However, the factors leading to these differences remain poorly understood. Here we studied the MTBC population in Dar es Salaam, Tanzania over a six-year period, using 1,082 unique patient-derived MTBC whole-genome sequences (WGS) and associated clinical data. We show that the TB epidemic in Dar es Salaam is dominated by multiple MTBC genotypes introduced to Tanzania...

Supplementary Material 2