2 Works

The antagonist of P2Y11 receptor NF157 ameliorates oxidized LDL-induced vascular endothelial inflammation

Yun Kuang, Hui Liu, Siyu Guo, Yufei Wang, Huijuan Zhang & Yanxiang Qiao
Atherosclerosis is the chronic inflammatory disease, and inflammation-elicited endothelial activation is an early event in the development of atherosclerosis. The P2Y11 receptor is a purinergic receptor and a member of the P2 family of G coupled protein which has been shown to modulate vascular function. Progress in the study of purine receptors has been tremendous and these receptors have become pharmacological targets for various diseases. In this study, we show that the P2Y11R antagonist NF157...

The antagonist of P2Y11 receptor NF157 ameliorates oxidized LDL-induced vascular endothelial inflammation

Yun Kuang, Hui Liu, Siyu Guo, Yufei Wang, Huijuan Zhang & Yanxiang Qiao
Atherosclerosis is the chronic inflammatory disease, and inflammation-elicited endothelial activation is an early event in the development of atherosclerosis. The P2Y11 receptor is a purinergic receptor and a member of the P2 family of G coupled protein which has been shown to modulate vascular function. Progress in the study of purine receptors has been tremendous and these receptors have become pharmacological targets for various diseases. In this study, we show that the P2Y11R antagonist NF157...

Registration Year

  • 2019
    2

Resource Types

  • Text
    2

Affiliations

  • Tianjin Medical University General Hospital
    2
  • Zhejiang University
    2
  • Huazhong University of Science and Technology
    2
  • Henan Normal University
    2
  • Heilongjiang Provincial Academy of Agricultural Sciences
    2
  • Sichuan University
    2
  • Tianjin Medical University Cancer Institute and Hospital
    2
  • Nanfang Hospital
    2
  • Bengbu Medical College
    2
  • Lanzhou University
    2