29 Works

Analyse von Mortalität nach Hüftfraktur auf Individual-, Krankenhaus- und regionaler Ebene in Deutschland

Claudia Schulz, Hans-Helmut König, Kilian Rapp, Clemens Becker, Dietrich Rothenbacher & Gisela Büchele
Einleitung. Die Mehrzahl der Studien, die die Mortalität nach Hüftfraktur analysieren, konzentrieren sich auf die Untersuchungsebene der Patienten und weniger auf die von Krankenhäusern oder Regionen. Ein tiefgreifendes Verständnis der beeinflussenden Faktoren aller Ebenen könnte jedoch dabei helfen, relevante Ungleichheiten aufzudecken, um Präventionsmaßnahmen zu motivieren und Verbesserungen in der Versorgung anzuregen. Daher untersuchte diese Studie die Variation der Mortalität nach Hüftfraktur auf Individual-, Krankenhaus- und regionaler Ebene in Deutschland. Methodik. Diese retrospektive Kohortenstudie basiert auf...

Mechanisms of change in Internet- and mobile-based interventions for PTSD: a systematic review and meta-analysis

Lena Steubl, Cedric Sachser, Harald Baumeister & Matthias Domhardt
Background: While Internet- and mobile-based interventions (IMIs) are potential options to increase the access to evidence-based therapies for post-traumatic stress disorder (PTSD), comprehensive knowledge on their working mechanisms is still scarce. Objective: We aimed to evaluate studies investigating the efficacy and mechanisms of change in IMIs for adults with PTSD. Method: In this systematic review and meta-analysis (PROSPERO CRD42019130314), five databases were consulted to identify relevant studies, complemented by forward (i.e. citation search) and backward...

Images obtained by fluorescence microscopy technique for monitoring diffusion of PI molecules into pressure-treated Listeria monocytogenes cells

Bahareh Nikparvar, Alicia Subires, Marta Capellas, Manuela Hernandez-Herrero, Peter Crauwels, Christian U. Riedel & Nadav Bar
The effect of environmental stresses on microorganisms is well studied and cellular response to stresses such as heat, cold, acids, and salts was extensively discussed. Although high pressure processing (HPP) as a preservation method is becoming more popular in the food industry, the characteristics of the cellular damage caused by high pressure are unclear, and the microbial response to this stress is not well explored yet. We exposed the pathogen Listeria monocytogenes to HPP (400...

Altering transcription factor binding reveals comprehensive transcriptional kinetics of a basic gene

Achim P. Popp, Johannes Hettich & J. Christof M. Gebhardt
Transcription is a vital process activated by transcription factor (TF) binding. The active gene releases a burst of transcripts before turning inactive again. While the basic course of transcription is well understood, it is unclear how binding of a TF affects the frequency, duration and size of a transcriptional burst. We systematically varied the residence time and concentration of a synthetic TF and characterized the transcription of a synthetic reporter gene by combining single molecule...

Age-related similarities and differences in networks of acute trauma-related stress symptoms in younger and older preschool children

Lasse Bartels, Cedric Sachser & Markus A. Landolt
Background: Prior research on trauma-exposed preschool children has found various levels of trauma-related stress symptoms depending on age, which might be explained by developmental factors. Objective: This study uses network analysis to extend prior research and compare symptom presentation in younger and older preschoolers in the acute phase (first 4 weeks) following a potentially traumatic event. Method: Parent-reported trauma-related acute stress symptoms were assessed using the Pediatric Emotional Distress Scale – Early Screener via www.kidtrauma.com....

Age-related similarities and differences in networks of acute trauma-related stress symptoms in younger and older preschool children

Lasse Bartels, Cedric Sachser & Markus A. Landolt
Background: Prior research on trauma-exposed preschool children has found various levels of trauma-related stress symptoms depending on age, which might be explained by developmental factors. Objective: This study uses network analysis to extend prior research and compare symptom presentation in younger and older preschoolers in the acute phase (first 4 weeks) following a potentially traumatic event. Method: Parent-reported trauma-related acute stress symptoms were assessed using the Pediatric Emotional Distress Scale – Early Screener via www.kidtrauma.com....

Acute radiation syndrome-related gene expression in irradiated peripheral blood cell populations

Patrick Ostheim, Alan Don Mallawaratchy, Thomas Müller, Simone Schüle, Cornelius Hermann, Tanja Popp, Stefan Eder, Stephanie E. Combs, Matthias Port & Michael Abend
In a nuclear or radiological event, an early diagnostic tool is needed to distinguish the worried well from those individuals who may later develop life-threatenFing hematologic acute radiation syndrome. We examined the contribution of the peripheral blood's cell populations on radiation-induced gene expression (GE) changes. EDTA-whole-blood from six healthy donors was X-irradiated with 0 and 4Gy and T-lymphocytes, B-lymphocytes, NK-cells and granulocytes were separated using immunomagnetic methods. GE were examined in cell populations and whole...

Hydraulic prediction of drought-induced plant dieback and top-kill depends on leaf habit and growth form

Ya-Jun Chen, Brendan Choat, Frank Sterck, Phisamai Maenpuen, Masatoshi Katabuchi, Shu-Bin Zhang, Kyle Tomlinson, Rafael Oliveira, Yong-Jiang Zhang, Kun-Fang Cao & Steven Jansen
Hydraulic failure caused by severe drought contributes to aboveground dieback and whole-plant death. The extent to which dieback or whole-plant death can be predicted by plant hydraulic traits has rarely been tested among species with different leaf habits and/or growth forms. We investigated 19 hydraulic traits in 40 woody species in a tropical savanna and their potential correlations with drought response during an extreme drought event during the El Niño–Southern Oscillation in 2015. Plant hydraulic...

Single molecule tracking and analysis framework including theory-predicted parameter settings

Timo Kuhn, Johannes Hettich, Rubina Davtyan & J. Christof M. Gebhardt
Imaging, tracking and analyzing individual biomolecules in living systems is a powerful technology to obtain quantitative kinetic and spatial information such as reaction rates, diffusion coefficients and localization maps. Common tracking tools often operate on single movies and require additional manual steps to analyze whole data sets or to compare different experimental conditions. We report a fast and comprehensive single molecule tracking and analysis framework (TrackIt) to simultaneously process several multi‐movie data sets. A user‐friendly...

Age-related similarities and differences in networks of acute trauma-related stress symptoms in younger and older preschool children

Lasse Bartels, Cedric Sachser & Markus A. Landolt
Prior research on trauma-exposed preschool children has found various levels of trauma-related stress symptoms depending on age, which might be explained by developmental factors. This study uses network analysis to extend prior research and compare symptom presentation in younger and older preschoolers in the acute phase (first 4 weeks) following a potentially traumatic event. Parent-reported trauma-related acute stress symptoms were assessed using the Pediatric Emotional Distress Scale – Early Screener via www.kidtrauma.com. First, the overall...

16S rRNA V4 gut microbiome of Leptonycteris yerbabuenae in Mexico

Luis Viquez-R
Migratory animals live in a world of constant change. Animals undergo many physiological changes preparing themselves for the migration. Although this field has been extensively studied over the last decades, we know relatively little about the seasonal changes that occur in the microbial communities that these animals carry in their guts. Here we assessed the V4 region of the 16S rRNA high-throughput sequencing data as a proxy to estimate microbiome diversity of Tequila Bats from...

Functional biogeography of Neotropical moist forests: trait-climate relationships and assembly patterns of tree communities

Bruno Pinho, Marcelo Tabarelli, Cajo Ter Braak, S. J. Wright, Victor Arroyo-Rodriguez, Maíra Benchimol, Bettina Engelbrecht, Simon Pierce, Peter Hietz, Bráulio Santos, Carlos Peres, Sandra Müller, Ian Wright, Frans Bongers, Madelon Lohbeck, Ülo Niinemets, Martijn Slot, Steven Jansen, Davi Jamelli, Renato Augusto Ferreira De Lima, Nathan Swenson, Richard Condit, Jos Barlow, Ferry Slik, Manuel Hernández-Ruedas … & Felipe Melo
Aim: Here we examine the functional profile of regional tree species pools across the latitudinal distribution of Neotropical moist forests, and test trait-climate relationships among local communities. We expected opportunistic strategies (acquisitive traits, small seeds) to be overrepresented in species pools further from the equator due to long-term instability, but also in terms of abundance in local communities in currently wetter, warmer and more seasonal climates. Location: Neotropics. Time period: Recent. Major taxa studied: Trees....

Self-assembled orthoester cryptands: orthoester scope, post-functionalization, kinetic locking and tunable degradation kinetics

Max von Delius, Henrik Löw & Elena Mena-Osteritz
Self-assembled orthoester cryptands offer appealing properties for applications in ion sensing and transport, such as convenient post-functionalization and tunable biodegradation.

Methodological Framework for Modelling and Empirical Approaches (Deliverable D1.1 in the EC ITN project SHAPE-IT)

Nikol Figalova, Naomi Mbelekani, Chi Zhang, Yue Yang, Chen Peng, Mohamed Nasser, Liu Yuan-Cheng, Amna Pir Muhammad, Wilbert Tabone, Siri Hegna Berge, Sarang Jokhio, Xiaolin He, Amir Hossein Kalantari, Ali Mohammadi, Xiaomi Yang, Bärgman Jonas & Baumann Martin

Acute Radiation Syndrome-related gene expression in irradiated peripheral blood cell populations

Patrick Ostheim, Alan Don Mallawaratchy, Thomas Müller, Simone Schüle, Cornelius Hermann, Tanja Popp, Stefan Eder, Stephanie E. Combs, Matthias Port & Michael Abend
In a nuclear or radiological event, an early diagnostic or prognostic tool is needed to distinguish the worried well from low-exposed and those individuals who may later develop life-threatening hematologic acute radiation syndrome (H-ARS). In previous studies, we identified and validated genes in peripheral blood for this purpose. To gain a deeper understanding and to make methodological improvements, we examined the contribution of the peripheral blood´s cell populations on radiation-induced gene expression changes. EDTA whole...

Mechanisms of change in Internet- and mobile-based interventions for PTSD: a systematic review and meta-analysis

Lena Steubl, Cedric Sachser, Harald Baumeister & Matthias Domhardt
Background: While Internet- and mobile-based interventions (IMIs) are potential options to increase the access to evidence-based therapies for post-traumatic stress disorder (PTSD), comprehensive knowledge on their working mechanisms is still scarce. Objective: We aimed to evaluate studies investigating the efficacy and mechanisms of change in IMIs for adults with PTSD. Method: In this systematic review and meta-analysis (PROSPERO CRD42019130314), five databases were consulted to identify relevant studies, complemented by forward (i.e. citation search) and backward...

Data from: Males benefit personally from family life: evidence from a wild burying beetle population

Eva M. Keppner & Sandra Steiger
Family life in animals is often considered as beneficial for offspring but costly for parents. However, parents might also profit from remaining aggregated within a family unit, especially if a nutrient-rich resource is used for reproduction. We aimed to reveal the potential personal benefits of breeding within a family environment for male Nicrophorus vespilloides, a species of burying beetles that use small vertebrate cadavers to raise their larvae. We previously hypothesized that males obtain an...

Methodological Framework for Modelling and Empirical Approaches (Deliverable D1.1 in the EC ITN project SHAPE-IT)

Nikol Figalova, Naomi Mbelekani, Chi Zhang, Yue Kang, Chen Peng, Mohamed Nasser, Liu Yuan-Cheng, Amna Pir Muhammad, Wilbert Tabone, Siri Hegna Berge, Sarang Jokhio, Xiaolin He, Amir Hossein Kalantari, Ali Mohammadi & Xiaomi Yang

Self-templated synthesis of an orthoformate in,in-cryptand and its bridgehead inversion by dynamic covalent exchange

Max von Delius, Henrik Löw & Elena Mena-Osteritz
We report the template-free dynamic covalent self-assembly of a small orthoformate cryptand, which appears to be driven by the formation of two sets of intramolecular, four-centre hydrogen bonds.

Self‐Assembly, Adaptive Response, and in , out‐ Stereoisomerism of Large Orthoformate Cryptands

Max von Delius, Henrik Löw, Elena Mena‐Osteritz, Kathleen M. Mullen & Christof Jäger
Abstract We report on triethylene glycol-based orthoformate cryptands, which adapt their bridgehead configurations in response to metal templates and intramolecular hydrogen bonding in a complex ma...

Incidents of aggression in German psychiatric hospitals: Is there an increase?

Frank Eisele, Erich Flammer & Tilman Steinert
Introduction: In a meta-analysis of international studies, 17% of admitted patients in psychiatric hospitals had shown violent behaviour towards others. Reported data from studies in Germany were considerably lower until now. However, studies referred to single hospitals and data quality was questionable. It is under discussion whether there is an increase of violent incidents. Methods: In a group of 10 hospitals serving about half of the population of the Federal State of Baden-Wuerttemberg with 11...

Acute radiation syndrome-related gene expression in irradiated peripheral blood cell populations

Patrick Ostheim, Alan Don Mallawaratchy, Thomas Müller, Simone Schüle, Cornelius Hermann, Tanja Popp, Stefan Eder, Stephanie E. Combs, Matthias Port & Michael Abend
In a nuclear or radiological event, an early diagnostic tool is needed to distinguish the worried well from those individuals who may later develop life-threatenFing hematologic acute radiation syndrome. We examined the contribution of the peripheral blood's cell populations on radiation-induced gene expression (GE) changes. EDTA-whole-blood from six healthy donors was X-irradiated with 0 and 4Gy and T-lymphocytes, B-lymphocytes, NK-cells and granulocytes were separated using immunomagnetic methods. GE were examined in cell populations and whole...

An Overview of Interfaces for Automated Vehicles (inside/outside) (Deliverable D2.1 in the H2020 MSCA ITN project SHAPE-IT)

Natasha Merat, Yue Yang, Yee Mun Lee, Siri Hegna Berge, Nikol Figalova, Sarang Jokhio, Chen Peng, Naomi Mbelekani, Mohamed Nasser, Amna Pir Muhammad, Wilbert Tabone, Liu Yuan-Cheng, Martin Baumann & Jonas Bärgman

NMR Studies on Li+, Na+ and K+ Complexes of Orthoester Cryptand o-Me2-1.1.1

René-Chris Brachvogel, Harald Maid & Max von Delius
Cryptands, a class of three-dimensional macrobicyclic hosts ideally suited for accommodating small guest ions, have played an important role in the early development of supramolecular chemistry. In contrast to related two-dimensional crown ethers, cryptands have so far only found limited applications, owing in large part to their relatively inefficient multistep synthesis. We have recently described a convenient one-pot, template synthesis of cryptands based on O,O,O-orthoesters acting as bridgeheads. Here we report variable-temperature, 1H-1D EXSY and...

Evidence for anion-binding of all-cis hexafluorocyclohexane in solution and solid state

Oleksandr Shyshov, Kevin Andre Siewerth & Max von Delius
We report a solution NMR and X-ray crystallographic study on the anion affinity of all-cis 1,2,3,4,5,6-hexafluorocyclohexane, which has only recently become synthetically accessible.

Registration Year

  • 2021
    29

Resource Types

  • Dataset
    20
  • Text
    9

Affiliations

  • University of Ulm
    29
  • Technical University of Munich
    6
  • Institute of Organic Chemistry
    4
  • University of Zurich
    4
  • Helmholtz Zentrum München
    3
  • University Hospital Regensburg
    3
  • University of Leeds
    3
  • Friedrich-Loeffler-Institut
    3
  • Delft University of Technology
    3
  • University of Bern
    3