100 Works
Additional file 2 of Optimising a person-centred approach to stopping medicines in older people with multimorbidity and polypharmacy using the DExTruS framework: a realist review
Amadea Turk, Geoffrey Wong, Kamal R. Mahtani, Michelle Madden, Ruaraidh Hill, Ed Ranson, Emma Wallace, Janet Krska, Dee Mangin, Richard Byng, Daniel Lasserson & Joanne Reeve
Additional file 2. Table of included documents.
Additional file 2 of The multimorbidity collaborative medication review and decision making (MyComrade) study: a pilot cluster randomised trial in two healthcare systems
Collette Kirwan, Lisa Hynes, Nigel Hart, Sarah Mulligan, Claire Leathem, Laura McQuillan, Marina Maxwell, Emma Carr, Kevin Roche, Scott Walkin, Caroline McCarthy, Colin Bradley, Molly Byrne, Susan M. Smith, Carmel Hughes, Maura Corry, Patricia M. Kearney, Geraldine McCarthy, Margaret Cupples, Paddy Gillespie, Anna Hobbins, John Newell, Liam Glynn, Davood Roshan, Carol Sinnott … & Andrew W. Murphy
Additional file 2. Incentives [6, 8, 17].
Additional file 1 of Factors influencing prescribing by critical care physicians to heart failure patients in Egypt: a cross-sectional survey
Seif El Hadidi, Naglaa Samir Bazan, Stephen Byrne, Ebtissam Darweesh & Margaret Bermingham
Additional file 1: Survey instrument.
The effectiveness and acceptability of evidence synthesis summary formats for clinical guideline development groups: a mixed-methods systematic review
Melissa K. Sharp, Dayang Anis Binti Awang Baki, Joan Quigley, Barrie Tyner, Declan Devane, Kamal R. Mahtani, Susan M. Smith, Michelle O’Neill, Máirín Ryan & Barbara Clyne
Abstract Introduction Clinical guideline development often involves a rigorous synthesis of evidence involving multidisciplinary stakeholders with different priorities and knowledge of evidence synthesis; this makes communicating findings complex. Summary formats are typically used to communicate the results of evidence syntheses; however, there is little consensus on which formats are most effective and acceptable for different stakeholders. Methods This mixed-methods systematic review (MMSR) aimed to evaluate the effectiveness and acceptability (e.g. preferences and attitudes and preferences...
Exploiting lactic acid bacteria for colorectal cancer: a recent update
Yang Chen, Bo Yang, Jianxin Zhao, R. Paul Ross, Catherine Stanton, Hao Zhang & Wei Chen
Colorectal cancer (CRC) is the third most common cancer in the world. Currently, chemotherapy and radiotherapy used to treat CRC exhibit many side effects, hence, it is an urgent need to design effective therapies to prevent and treat CRC. Lactic acid bacteria (LAB) can regulate gut microbiota, intestinal immunity, and intestinal mechanical barrier, which is becoming a hot product for the prevention and treatment of CRC, whereas comprehensive reviews of their anti-CRC mechanisms are limited....
Additional file 2 of Effective maNagement of depression among patients witH cANCEr (ENHANCE): a protocol for a hybrid systematic review and network meta-analysis of randomised controlled trials of interventions for depressive symptoms
Maria M. Pertl, Sergio Perez, Sonya Collier, Emer Guinan, Garret Monahan, Katie Verling, Emma Wallace, Aisling Walsh & Frank Doyle
Additional file 2: Table 1. ENHANCE project Public and Patient Involvement: GRIPP2 short form.
Effective maNagement of depression among patients witH cANCEr (ENHANCE): a protocol for a hybrid systematic review and network meta-analysis of randomised controlled trials of interventions for depressive symptoms
Maria M. Pertl, Sergio Perez, Sonya Collier, Emer Guinan, Garret Monahan, Katie Verling, Emma Wallace, Aisling Walsh & Frank Doyle
Abstract Background Depression is common among patients with cancer and is associated with lower treatment participation, lower satisfaction with care, poorer quality of life, greater symptom burden and higher healthcare costs. Various types of interventions (e.g. pharmacological, psychotherapy) are used for the treatment of depression. However, evidence for these among patients with cancer is limited. Furthermore, the relative effectiveness and acceptability of different approaches are unknown because a direct comparison between all available treatments has...
Effective maNagement of depression among patients witH cANCEr (ENHANCE): a protocol for a hybrid systematic review and network meta-analysis of randomised controlled trials of interventions for depressive symptoms
Maria M. Pertl, Sergio Perez, Sonya Collier, Emer Guinan, Garret Monahan, Katie Verling, Emma Wallace, Aisling Walsh & Frank Doyle
Abstract Background Depression is common among patients with cancer and is associated with lower treatment participation, lower satisfaction with care, poorer quality of life, greater symptom burden and higher healthcare costs. Various types of interventions (e.g. pharmacological, psychotherapy) are used for the treatment of depression. However, evidence for these among patients with cancer is limited. Furthermore, the relative effectiveness and acceptability of different approaches are unknown because a direct comparison between all available treatments has...
The opportunity for selection: an important but slippery concept in ecology and evolution.
Thomas Reed, Thomas Reed, Marcel E. Visser & Robin Waples
1. The concept of the opportunity for selection (I), measured as the variance in relative fitness, is over 60 years old, yet remains poorly understood by, or even unknown to, many ecologists and evolutionary biologists. This essay aims to clarify key conceptual and practical issues concerning use and estimation of I, which represents a theoretical upper limit on the rate of evolutionary adaptation. 2. The component of I caused by linear selection on a single...
Additional file 6 of The effectiveness and acceptability of evidence synthesis summary formats for clinical guideline development groups: a mixed-methods systematic review
Melissa K. Sharp, Dayang Anis Binti Awang Baki, Joan Quigley, Barrie Tyner, Declan Devane, Kamal R. Mahtani, Susan M. Smith, Michelle O’Neill, Máirín Ryan & Barbara Clyne
Additional file 6: Figures 6, 7, and 8. Recommendations for Practice.
Additional file 1 of The effectiveness and acceptability of evidence synthesis summary formats for clinical guideline development groups: a mixed-methods systematic review
Melissa K. Sharp, Dayang Anis Binti Awang Baki, Joan Quigley, Barrie Tyner, Declan Devane, Kamal R. Mahtani, Susan M. Smith, Michelle O’Neill, Máirín Ryan & Barbara Clyne
Additional file 1. PRISMA checklist.
How do trial teams plan for retention during the design stage of the trial? A scoping review protocol
Ellen Murphy, Katie Gillies & Frances Shiely
Abstract Background Retention remains a major challenge for many clinical trials. The SPIRIT guidelines state the following information on retention should be included in the trial protocol “Plans to promote participant retention and complete follow-up, including list of any outcome data to be collected for participants who discontinue or deviate from intervention protocols”. This guidance shows the importance of planning retention methods and handling missing data as this can impact how the results of the...
How do trial teams plan for retention during the design stage of the trial? A scoping review protocol
Ellen Murphy, Katie Gillies & Frances Shiely
Abstract Background Retention remains a major challenge for many clinical trials. The SPIRIT guidelines state the following information on retention should be included in the trial protocol “Plans to promote participant retention and complete follow-up, including list of any outcome data to be collected for participants who discontinue or deviate from intervention protocols”. This guidance shows the importance of planning retention methods and handling missing data as this can impact how the results of the...
Preferred Reporting Items for Systematic review and Meta-Analysis Protocols (PRISMA-P) checklist and flow diagram
Elizabeth Bodunde, Daire Buckley, Eimear O'Neill, Gillian M. Maher, Karen Matvienko-Sikar, Karen O'Connor., Fergus P. McCarthy & Ali S. Khashan
PRISMA-P Checklist PRISMA flow diagram
Supplemental Material – Community paediatric clinics and their role in supporting developmental outcomes and services for children living in disadvantaged communities
Lynn Buckley, Louise Gibson, Katherine Harford, Nicola Cornally & Margaret Curtin
Supplemental Material for Community paediatric clinics and their role in supporting developmental outcomes and services for children living in disadvantaged communities by Lynn Buckley, Louise Gibson, Katherine Harford, Nicola Cornally, and Margaret Curtin in the Journal of Child Health Care.
Preferred Reporting Items for Systematic review and Meta-Analysis Protocols (PRISMA-P) checklist and flow diagram
Elizabeth Bodunde, Daire Buckley, Eimear O'Neill, Gillian M. Maher, Karen Matvienko-Sikar, Karen O'Connor., Fergus P. McCarthy & Ali S. Khashan
PRISMA-P Checklist PRISMA flow diagram
Factors influencing prescribing by critical care physicians to heart failure patients in Egypt: a cross-sectional survey
Seif El Hadidi, Naglaa Samir Bazan, Stephen Byrne, Ebtissam Darweesh & Margaret Bermingham
Abstract Background Heart failure (HF) guideline-led prescribing improves patient outcomes; however, little is known about the factors influencing guideline-led prescribing in critical care settings. This study used a cross-sectional survey to assess the factors that influence physicians when prescribing to heart failure patients in a critical care setting in Egypt. Results The response rate was 54.8%. The international HF guidelines were the primary source of prescribing information for 84.2% of respondents. Staff were more familiar...
A general swimming response in exhausted obligate swimming fish
Gil Iosilevskii, Jacinta Kong, Carl Meyer, Yuuki Watanabe, Yannis Papastamatiou, Mark Royer, Itsumi Nakamura, Katsufumi Sato, Thomas Doyle, Luke Harman, Jonathan Houghton, Adam Barnett, Jayson Semmens, Niall Ó Maoléidigh, Alan Drumm, Ross O'Neill, Daniel Coffey & Nicholas Payne
Marine organisms normally swim at elevated speeds relative to cruising speeds only during strenuous activity, such as predation or escape. We measured swimming speeds of 29 ram ventilating sharks from 10 species and of three Atlantic bluefin tunas immediately after exhaustive exercise (fighting a capture by hook-and-line), and unexpectedly found all individuals exhibited a uniform mechanical response, with swimming speed initially 2 times higher than the cruising speeds reached approximately 6 hours later. We hypothesised...
Additional file 7 of The effectiveness and acceptability of evidence synthesis summary formats for clinical guideline development groups: a mixed-methods systematic review
Melissa K. Sharp, Dayang Anis Binti Awang Baki, Joan Quigley, Barrie Tyner, Declan Devane, Kamal R. Mahtani, Susan M. Smith, Michelle O’Neill, Máirín Ryan & Barbara Clyne
Additional file 7. Qualitative synthesis recommendations (with at least 3 supporting studies or mixed methods support).
Additional file 3 of Optimising a person-centred approach to stopping medicines in older people with multimorbidity and polypharmacy using the DExTruS framework: a realist review
Amadea Turk, Geoffrey Wong, Kamal R. Mahtani, Michelle Maden, Ruaraidh Hill, Ed Ranson, Emma Wallace, Janet Krska, Dee Mangin, Richard Byng, Daniel Lasserson & Joanne Reeve
Additional file 3. CMOCs with supporting data extracts.
Public beliefs about the consequences of living with obesity in the Republic of Ireland and Northern Ireland
Eleni Spyreli, L McGowan, E Heery, A Kelly, H Croker, C Lawlor, R O’Neill, CC Kelleher, M McCarthy, P Wall & MM Heinen
Abstract Background This study aimed to capture public beliefs about living with obesity, examine how these beliefs have changed over time and to explore whether certain characteristics were associated with them in a nationally representative sample of adults from the Republic of Ireland (RoI) and Northern Ireland (NI). Methods A cross-sectional survey employed a random quota sampling approach to recruit a nationally representative sample of 1046 adults across NI and RoI. Telephone interviews captured information...
The effectiveness and acceptability of evidence synthesis summary formats for clinical guideline development groups: a mixed-methods systematic review
Melissa K. Sharp, Dayang Anis Binti Awang Baki, Joan Quigley, Barrie Tyner, Declan Devane, Kamal R. Mahtani, Susan M. Smith, Michelle O’Neill, Máirín Ryan & Barbara Clyne
Abstract Introduction Clinical guideline development often involves a rigorous synthesis of evidence involving multidisciplinary stakeholders with different priorities and knowledge of evidence synthesis; this makes communicating findings complex. Summary formats are typically used to communicate the results of evidence syntheses; however, there is little consensus on which formats are most effective and acceptable for different stakeholders. Methods This mixed-methods systematic review (MMSR) aimed to evaluate the effectiveness and acceptability (e.g. preferences and attitudes and preferences...
Additional file 1 of Measuring the effects of misinformation exposure and beliefs on behavioural intentions: a COVID-19 vaccination study
Constance de Saint Laurent, Gillian Murphy, Karen Hegarty & Ciara M. Greene
Additional file 1: Supplemental materials.
Additional file 1 of Measuring the effects of misinformation exposure and beliefs on behavioural intentions: a COVID-19 vaccination study
Constance de Saint Laurent, Gillian Murphy, Karen Hegarty & Ciara M. Greene
Additional file 1: Supplemental materials.
Additional file 1 of The multimorbidity collaborative medication review and decision making (MyComrade) study: a pilot cluster randomised trial in two healthcare systems
Collette Kirwan, Lisa Hynes, Nigel Hart, Sarah Mulligan, Claire Leathem, Laura McQuillan, Marina Maxwell, Emma Carr, Kevin Roche, Scott Walkin, Caroline McCarthy, Colin Bradley, Molly Byrne, Susan M. Smith, Carmel Hughes, Maura Corry, Patricia M. Kearney, Geraldine McCarthy, Margaret Cupples, Paddy Gillespie, Anna Hobbins, John Newell, Liam Glynn, Davood Roshan, Carol Sinnott … & Andrew W. Murphy
Additional file 1. Recruitment [4, 22, 24, 36, 43, 51, 52].
Affiliations
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University College Cork100
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Royal College of Surgeons in Ireland44
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Trinity College Dublin33
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Cork University Hospital33
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University of Oxford32
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National University of Ireland, Galway28
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University College Dublin15
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Queen's University Belfast13
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University of Plymouth12
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Medway School of Pharmacy12