4 Works

RETRACTED ARTICLE: Linc00152 promotes malignant progression of glioma stem cells by regulating miR-103a-3p/FEZF1/CDC25A pathway

Mingjun Yu, Yixue Xue, Jian Zheng, Xiaobai Liu, Hai Yu, Libo Liu, Zhen Li & Yunhui Liu
Collection published via figshare
Abstract Background Glioma is one of the most frequent intracranial malignant tumors. LncRNAs have been identified as new modulators in the origination and progression of glioma. Methods Quantitative real-time PCR were conducted to evaluate the expression of linc00152 and miRNA-103a-3p in glioma tissues and cells. Western blot were used to determine the expression of FEZF1 and CDC25A in glioma tissues and cells. Stable knockdown of linc00152 or over-expression of miR-103a-3p in glioma stem cells (GSCs)...
No citations were reported. No usage information was reported.
https://doi.org/10.6084/m9.figshare.c.3812512 Cite

Linc00152 promotes malignant progression of glioma stem cells by regulating miR-103a-3p/FEZF1/CDC25A pathway

Mingjun Yu, Yixue Xue, Jian Zheng, Xiaobai Liu, Hai Yu, Libo Liu, Zhen Li & Yunhui Liu
Collection published via figshare
Abstract Background Glioma is one of the most frequent intracranial malignant tumors. LncRNAs have been identified as new modulators in the origination and progression of glioma. Methods Quantitative real-time PCR were conducted to evaluate the expression of linc00152 and miRNA-103a-3p in glioma tissues and cells. Western blot were used to determine the expression of FEZF1 and CDC25A in glioma tissues and cells. Stable knockdown of linc00152 or over-expression of miR-103a-3p in glioma stem cells (GSCs)...
No citations were reported. No usage information was reported.
https://doi.org/10.6084/m9.figshare.c.3812512.v1 Cite

Cell-penetrating peptide conjugates to enhance the antitumor effect of paclitaxel on drug-resistant lung cancer

Ziqing Duan, Cuitian Chen, Jing Qin, Qi Liu, Qi Wang, Xinchun Xu & Jianxin Wang
Journal Contribution published via Taylor & Francis
To conquer the drug resistance of tumors and the poor solubility of paclitaxel (PTX), two PTX-cell-penetrating peptide conjugates (PTX-CPPs), PTX-TAT and PTX-LMWP, were synthesized and evaluated for the first time. Compared with free PTX, PTX-CPPs displayed significantly enhanced cellular uptake, elevated cell toxicity, increased cell apoptosis, and decreased mitochondrial membrane potential (Δψm) in both A549 and A549T cells. PTX-LMWP exhibited a stronger inhibitory effect than PTX-TAT in A549T cells. Analysis of cell-cycle distribution showed that...
No citations were reported. No usage information was reported.
https://doi.org/10.6084/m9.figshare.4970141.v1 Cite

Cell-penetrating peptide conjugates to enhance the antitumor effect of paclitaxel on drug-resistant lung cancer

Ziqing Duan, Cuitian Chen, Jing Qin, Qi Liu, Qi Wang, Xinchun Xu & Jianxin Wang
Journal Contribution published via Taylor & Francis
To conquer the drug resistance of tumors and the poor solubility of paclitaxel (PTX), two PTX-cell-penetrating peptide conjugates (PTX-CPPs), PTX-TAT and PTX-LMWP, were synthesized and evaluated for the first time. Compared with free PTX, PTX-CPPs displayed significantly enhanced cellular uptake, elevated cell toxicity, increased cell apoptosis, and decreased mitochondrial membrane potential (Δψm) in both A549 and A549T cells. PTX-LMWP exhibited a stronger inhibitory effect than PTX-TAT in A549T cells. Analysis of cell-cycle distribution showed that...
No citations were reported. No usage information was reported.
https://doi.org/10.6084/m9.figshare.4970141 Cite

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  • West China Hospital of Sichuan University
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  • Zhejiang University
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  • Air Force Medical University
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  • Chinese Academy of Medical Sciences & Peking Union Medical College
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  • China Medical University
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  • State Administration of Traditional Chinese Medicine of the People's Republic of China
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  • Central South University
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  • Xiamen University
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  • Fudan University Shanghai Cancer Center
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  • Huazhong University of Science and Technology
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