613 Works

3D images of a turtle embryo

Yuzheng Ke, Rui Wu, Darla Zelenitsky, Don Brinkman, Jinfeng Hu, Shukang Zhang, Haishui Jiang & Fenglu Han
Turtle eggs containing embryos are exceedingly rare in the fossil record. Here, we provide the first description and taxonomic identification, to our knowledge, of a fossilized embryonic turtle preserved in an egg, a fossil recovered from the Upper Cretaceous Xiaguan Formation of Henan Province, China. Through Computed Tomography and Three-Dimensional reconstruction, many bones can be clearly displayed, including the maxillae, mandibles, ribs, plastral plates, scapula, forelimbs, and hind limbs. The specimen is attributed to the...

DHX9 interacts with APOBEC3B and attenuates the anti-HBV effect of APOBEC3B

Yanmeng Chen, Bocun Shen, Xiaochuan Zheng, Quanxin Long, Jie Xia, Yao Huang, Xuefei Cai, Deqiang Wang, Juan Chen, Ni Tang, Ailong Huang & Yuan Hu
Hepatitis B virus (HBV) is a partially double-stranded DNA virus that replicates by reverse transcription. We previously demonstrated that the host restriction factor-APOBEC3B (A3B) inhibited HBV replication which was dependent on its deaminase activity during reverse transcription. However, the host factors involved in the process of regulating the anti-HBV function of A3B are less known. In this research, to obtain a comprehensive understanding of the interaction networks of A3B, we conducted coimmunoprecipitation and mass spectrometry...

RETRACTED ARTICLE: Neferine hinders choriocarcinoma cell proliferation, migration and invasion through repression of long noncoding RNA-CHRF

Gang Wang, Ping Wang, Xiaojun Yan & Jing Liu
We, the Editors and Publisher of the journal Artificial Cells, Nanomedicine, and Biotechnology, have retracted the following article: Gang Wang, Ping Wang, Xiaojun Yan & Jing Liu (2019) Neferine hinders choriocarcinoma cell proliferation, migration and invasion through repression of long noncoding RNA-CHRF, Artificial Cells, Nanomedicine, and Biotechnology, 47:1, 4089–4096, DOI: 10.1080/21691401.2019.1671429 Since publication, concerns have been raised about the integrity of the data in the article. When approached for an explanation, the authors have been...

The complete mitochondrial genome of Eutrichosiphum pasaniae (Okajima, 1908) (Hemiptera: Aphididae: Greenideinae)

Cailing Li, Liyun Jiang, Xiaolu Zhang, Jing Chen & Gexia Qiao
In this study, we sequenced the complete mitochondrial genome of Eutrichosiphum pasaniae through Illumina platform. The circular mitogenome is 16,500 bp in length and composed of 13 protein-coding genes (PCGs), 22 transfer RNA genes (tRNAs), 2 ribosomal RNA genes (rRNAs), a large control region and a special repeat region. The nucleotide composition of whole mitogenome is strongly AT-biased (85.5%). All PCGs start with ATN and end with TAA except for cox1 which terminates with an...

Additional file 5 of Data integration and evolutionary analysis of long non-coding RNAs in 25 flowering plants

Shiye Sang, Wen Chen, Di Zhang, Xuan Zhang, Wenjing Yang & Changning Liu
Additional file 5. Download path of FASTA sequences for the lncRNAs from 25 plants.

Additional file 5 of Data integration and evolutionary analysis of long non-coding RNAs in 25 flowering plants

Shiye Sang, Wen Chen, Di Zhang, Xuan Zhang, Wenjing Yang & Changning Liu
Additional file 5. Download path of FASTA sequences for the lncRNAs from 25 plants.

Additional file 8 of Temporal expression study of miRNAs in the crown tissues of winter wheat grown under natural growth conditions

Menglei Wang, Chenhui Yang, Kangning Wei, Miao Zhao, Liqiang Shen, Jie Ji, Li Wang, Daijing Zhang, Junqiang Guo, Yun Zheng, Juanjuan Yu, Mo Zhu, Haiying Liu & Yong-Fang Li
Additional file 8: Table S5. Sequence of primers used in this study.

β-galactosidase GALA from Bacillus circulans with high transgalactosylation activity

Yaru Yan, Weishi Guan, Xiaoyi Li, Kaier Gao, Xinxin Xu, Bo Liu, Wei Zhang & Yuhong Zhang
β-galactosidase catalyzes lactose hydrolysis and transfers reactions to produce prebiotics such as galacto-oligosaccharides (GOS) with potential applications in the food industry and pharmaceuticals. However, there is still a need for improved transgalactosylation activity of β-galactosidases and reaction conditions of GOS production in order to maximize GOS output and reduce production costs. In this study, a β-galactosidase gene, galA, from Bacillus circulans was expressed in Pichia pastoris, which not only hydrolyzed lactose but also had strong...

Nonlinear responses of ecosystem carbon fluxes to nitrogen deposition in an old-growth boreal forest

Aijun Xing, Enzai Du, Haihua Shen, Longchao Xu, Wim De Vries, Mengying Zhao, Xiuyuan Liu & Jingyun Fang
Nitrogen (N) deposition is known to increase carbon (C) sequestration in N-limited boreal forests. However, the long-term effects of N deposition on ecosystem carbon fluxes have been rarely investigated in old-growth boreal forests. Here we show that decade-long experimental N additions significantly stimulated net primary production (NPP) but the effect decreased with increasing N loads. The effect on soil heterotrophic respiration (Rh) shifted from a stimulation at low-level N additions to an inhibition at higher...

Silmitasertib-induced macropinocytosis promoting DDP intracellular uptake to enhance cell apoptosis in oral squamous cell carcinoma

Shaojuan Song, Xin Xia, Jiajia Qi, Xiaopei Hu, Qian Chen, Jiang Liu, Ning Ji & Hang Zhao
Cisplatin (DDP) is a first-line chemotherapeutic drug applied for the treatment of oral squamous cell carcinoma (OSCC). The anticancer activity of DDP is tightly linked to its intracellular uptake. It is unwise to increase the DDP intake by increasing the dose or shortening the dosing interval because of the severe systemic toxicity (nephrotoxicity, ototoxicity and neurotoxicity) in DDP application. The main uptake pathways of DDP include passive diffusion and active transporter transport. Therefore, finding additional...

Three‐dimensional soil heterogeneity modulates responses of grassland mesocosms to an experimentally imposed drought extreme

Yongjie Liu, Michiel F. Bortier, Ivan Nijs, Yongshuo Fu, Zhenqing Li, Fujiang Hou & Hans J. De Boeck
Heterogeneity is an intrinsic characteristic of soils, which regulates plant diversity and ecosystem functioning. However, whether soil heterogeneity also modulates responses of plant communities to climate change, including climate extremes, remains largely an open question. Here, we explore responses of plant communities to drought extremes across four levels of spatial soil heterogeneity, with cell sizes varying from very small to very large, i.e. 0, 12, 24 and 48 cm. These were created in mesocosms by...

A novel transcription factor UvCGBP1 regulates development and virulence of rice false smut fungus Ustilaginoidea virens

Xiaoyang Chen, Pingping Li, Hao Liu, Xiaolin Chen, Junbin Huang, Chaoxi Luo, Guotian Li, Tom Hsiang, David B. Collinge & Lu Zheng
Ustilaginoidea virens, causing rice false smut (RFS) is an economically important ascomycetous fungal pathogen distributed in rice-growing regions worldwide. Here, we identified a novel transcription factor UvCGBP1 (Cutinase G-box binding protein) from this fungus, which is unique to ascomycetes. Deletion of UvCGBP1 affected development and virulence of U. virens. A total of 865 downstream target genes of UvCGBP1 was identified using ChIP-seq and the most significant KEGG enriched functional pathway was the MAPK signaling pathway....

Trypanosoma evansi evades host innate immunity by releasing extracellular vesicles to activate TLR2-AKT signaling pathway

Ran Wei, Xin Li, Xiaocen Wang, Nan Zhang, Yuru Wang, Xichen Zhang, Pengtao Gong & Jianhua Li
Surra, one of the most important animal diseases with economic consequences in Asia and South America, is caused by Trypanosoma evansi. However, the mechanism of immune evasion by T. evansi has not been extensively studied. In the present study, T. evansi extracellular vesicles (TeEVs) were characterized and the role of TeEVs in T. evansi infection were examined. The results showed that T. evansi and TeEVs could activate TLR2-AKT pathway to inhibit the secretions of IL-12p40,...

sj-pdf-1-jfi-10.1177_0192513X211041992 – Supplemental Material for Loneliness Among Chinese Older Adults: The Role of Grandparenthood and Grandparental Childcare by Gender

Jing Zhang, Tineke Fokkema & Bruno Arpino
Supplemental Material, sj-pdf-1-jfi-10.1177_0192513X211041992 for Loneliness Among Chinese Older Adults: The Role of Grandparenthood and Grandparental Childcare by Gender by Jing Zhang, Tineke Fokkema and Bruno Arpino in Journal of Family Issues

Loneliness Among Chinese Older Adults: The Role of Grandparenthood and Grandparental Childcare by Gender

Jing Zhang, Tineke Fokkema & Bruno Arpino
This study examines the influence of grandparenthood and grandparental childcare on loneliness among Chinese older adults. Using longitudinal data from a nationally representative sample of 9240 individuals from the China Health and Retirement Longitudinal Study (CHARLS), we applied logistic regression to examine the relationship between various grandparental statuses and loneliness with a focus on gender. The grandparental role is a protective factor for loneliness. Providing care to grandchildren was associated with a lower likelihood of...

Insights into small molecule inhibitor bindings to PD-L1 with residue-specific binding free energy calculation

Wei Xia, Liping He, Jingxiao Bao, Yifei Qi & John Z.H. Zhang
Targeting the immunological checkpoint PD-1/PD-L1 with antibodies has shown opportunities to improve cancer treatment in recent years. However, antibody therapy is a double-edged sword with high cost, low patient tolerance, lack of oral bioavailability, and a reaction to most solid tumors that prevents the adoption of antibodies. Advancement of small-molecule PD-1/PD-L1 inhibitors that could overwhelm these drawbacks is sluggish because of the poor pharmacodynamic properties and shallow pocket of the PD-1/PD-L1 binding interface. Recently, a...

Phylogenomic and macroevolutionary evidence for an explosive radiation of a plant genus in the Miocene

Hanghui Kong, Fabien L. Condamine, Lihua Yang, AJ Harris, Chao Feng, Fang Wen & Ming Kang
Mountain systems harbor a substantial fraction of global biodiversity and, thus, provide excellent opportunities to study rapid diversification and to understand the historical processes underlying the assembly of biodiversity hotspots. The rich biodiversity in mountains is widely regarded as having arisen under the influence of geological and climatic processes as well as the complex interactions among them. However, the relative contribution of geology and climate in driving species radiation is seldom explored. Here, we studied...

Lepidoptera caterpillars barcodes in FASTA format

Ming-Qiang Wang, Chuan Yan, Arong Luo, Yi Li, Douglas Chesters, Hui-Jie Qiao, Jing-Ting Chen, Qing-Song Zhou, Keping Ma, Helge Bruelheide, Andreas Schuldt, Zhibin Zhang & Chao-Dong Zhu
The dataset contains COI barcodes of Lepidoptera caterpillars collected from a subtropical forest in Jiangxi, China.

sj-pdf-1-ajs-10.1177_03635465211030259 – Supplemental material for Quadriceps Tendon Autograft Versus Bone–Patellar Tendon–Bone and Hamstring Tendon Autografts for Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis

Wenli Dai, Xi Leng, Jian Wang, Jin Cheng, Xiaoqing Hu & Yingfang Ao
Supplemental material, sj-pdf-1-ajs-10.1177_03635465211030259 for Quadriceps Tendon Autograft Versus Bone–Patellar Tendon–Bone and Hamstring Tendon Autografts for Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis by Wenli Dai, Xi Leng, Jian Wang, Jin Cheng, Xiaoqing Hu and Yingfang Ao in The American Journal of Sports Medicine

Quadriceps Tendon Autograft Versus Bone–Patellar Tendon–Bone and Hamstring Tendon Autografts for Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis

Wenli Dai, Xi Leng, Jian Wang, Jin Cheng, Xiaoqing Hu & Yingfang Ao
Background:The best type of autograft for anterior cruciate ligament (ACL) reconstruction remains debatable.Hypothesis:Compared with bone–patellar tendon–bone (BPTB) and hamstring tendon (HT) autografts, the quadriceps tendon (QT) autograft has comparable graft survival as well as clinical function and pain outcomes.Study Design:Meta-analysis; Level of evidence, 4.Methods:A systematic literature search was conducted in PubMed, Embase, Scopus, and the Cochrane Library to July 2020. Randomized controlled trials (RCTs) and observational studies reporting comparisons of QT versus BPTB or HT...

Comparison of the accelerating effect of graphene oxide and graphene on anaerobic transformation of bisphenol F by Pseudomonas sp. LS

Hong Lu, Jingyi Li, Ze Fu, Xiaolei Wang, Jiti Zhou & Jing Wang
It was found that bisphenol F (BPF) could be anaerobically transformed to 4,4-dihydroxybenzophenone using nitrate as an electron acceptor by Pseudomonas sp. LS. However, BPF removal was a slow process under anaerobic conditions. In the present study, effects of graphene oxide (GO) and graphene on the anaerobic transformation of BPF were studied in detail. Results showed that GO (2–10 mg/L) and graphene (2–20 mg/L) could increase the anaerobic biotransformation rate of BPF. For GO-mediated system,...

Construction of a novel risk model based on the random forest algorithm to distinguish pancreatic cancers with different prognoses and immune microenvironment features

Yalan Lei, Rong Tang, Jin Xu, Bo Zhang, Jiang Liu, Chen Liang, Qingcai Meng, Jie Hua, Xianjun Yu, Wei Wang & Si Shi
Immune-related long noncoding RNAs (irlncRNAs) are actively involved in regulating the immune status. This study aimed to establish a risk model of irlncRNAs and further investigate the roles of irlncRNAs in predicting prognosis and the immune landscape in pancreatic cancer. The transcriptome profiles and clinical information of 176 pancreatic cancer patients were retrieved from The Cancer Genome Atlas (TCGA). Immune-related genes (irgenes) downloaded from ImmPort were used to screen 1903 immune-related lncRNAs (irlncRNAs) using Pearson’s...

Complement receptor 3 mediates Aspergillus fumigatus internalization into alveolar epithelial cells with the increase of intracellular phosphatidic acid by activating FAK

Xuelin Han, Xueting Su, Zhiqian Li, Yanxi Liu, Shuo Wang, Miao Zhu, Changjian Zhang, Fan Yang, Jingya Zhao, Xianping Li, Fangyan Chen & Li Han
Complement receptor 3 (CD11b/CD18) is an important receptor that mediates adhesion, phagocytosis and chemotaxis in various immunocytes. The conidia of the medically-important pathogenic fungus, Aspergillus fumigatus can be internalized into alveolar epithelial cells to disseminate its infection in immunocompromised host; however, the role of CR3 in this process is poorly understood. In the present study, we investigated the potential role of CR3 on A. fumigatus internalization into type II alveolar epithelial cells and its effect...

Community species diversity mediates the trade-off between aboveground and belowground biomass for grasses and forbs in degraded alpine meadow, Tibetan Plateau

Tiancai Zhou
Although many empirical experiments have shown that increasing degradation results in lower aboveground biomass (AGB), our knowledge of the magnitude of belowground biomass (BGB) for individual plants is a prerequisite for accurately revealing the biomass trade-off in degraded grasslands. Here, by linking the AGB and BGB of individual plants, species in the community, and soil properties, we explored the biomass partitioning patterns in different plant functional groups (grasses of Stipa capillacea and forbs of Anaphalis...

β diversity among ant communities on fragmented habitat islands: the roles of species trait, phylogeny and abundance

Yuhao Zhao, Nathan Sanders, Juan Liu, Tinghao Jin, Haonan Zhou, Ruisen Lu, Ping Ding & Xingfeng Si
Habitat loss and fragmentation reduce biodiversity and alter species composition in local communities. β diversity describes the variation in species composition between or among communities in fragmented landscapes and has two components: species turnover and nestedness. In this study, we assessed β diversity of ant assemblages on 24 island fragments in the Thousand Island Lake, China. We constructed a species-level phylogenetic tree and measured five morphological traits of all ant species captured. We then assessed...

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