Data from: Antipsychotic dose mediates the association between polypharmacy and corrected QT interval

Corrado Barbui, Irene Bighelli, Giuseppe Carrà, Mariasole Castellazzi, Claudio Lucii, Giovanni Martinotti, Michela Nosè, Giovanni Ostuzzi & Giovanni Targher
Antipsychotic (AP) drugs have the potential to cause prolongation of the QT interval corrected for heart rate (QTc). As this risk is dose-dependent, it may be associated with the number of AP drugs concurrently prescribed, which is known to be associated with increased cumulative equivalent AP dosage. This study analysed whether AP dose mediates the relationship between polypharmacy and QTc interval. We used data from a cross-sectional survey that investigated the prevalence of QTc lengthening...

Registration Year

  • 2016
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Resource Types

  • Dataset
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Affiliations

  • University of Milan
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  • University of Milano-Bicocca
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  • University of Verona
    1