84 Works

Data from: No deep diving: evidence of predation on epipelagic fish for a stem beaked whale from the late Miocene of Peru

Olivier Lambert, Alberto Collareta, Walter Landini, Klaas Post, Benjamin Ramassamy, Claudio Di Celma, Mario Urbina-Schmitt & Giovanni Bianucci
Although modern beaked whales (Ziphiidae) are known to be highly specialized toothed whales that predominantly feed at great depths upon benthic and benthopelagic prey, only limited palaeontological data document this major ecological shift. We report on a ziphiid–fish assemblage from the Late Miocene of Peru that we interpret as the first direct evidence of a predator–prey relationship between a ziphiid and epipelagic fish. Preserved in a dolomite concretion, a skeleton of the stem ziphiid Messapicetus...

Data from: Intraneural stimulation elicits discrimination of textural features by artificial fingertip in intact and amputee humans

Calogero Maria Oddo, Stanisa Raspopovic, Fiorenzo Artoni, Alberto Mazzoni, Giacomo Spigler, Francesco Petrini, Giambattistelli Federica, Vecchio Fabrizio, Miraglia Francesca, Zollo Loredana, Giovanni Di Pino, Domenico Camboni, Maria Chiara Carrozza, Eugenio Guglielmelli, Paolo Maria Rossini, Ugo Faraguna & Silvestro Micera
Restoration of touch after hand amputation is a desirable feature of ideal prostheses. Here, we show that texture discrimination can be artificially provided in human subjects by implementing a neuromorphic real-time mechano-neuro-transduction (MNT), which emulates to some extent the firing dynamics of SA1 cutaneous afferents. The MNT process was used to modulate the temporal pattern of electrical spikes delivered to the human median nerve via percutaneous microstimulation in four intact subjects and via implanted intrafascicular...

Data from: A 45-second self-test for cardiorespiratory fitness: heart rate-based estimation in healthy individuals

Francesco Sartor, Matteo Bonato, Gabriele Papini, Andrea Bosio, Rahil A. Mohammed, Alberto G. Bonomi, Jonathan P. Moore, Giampiero Merati, Antonio La Torre & Hans-Peter Kubis
Cardio-respiratory fitness (CRF) is a widespread essential indicator in Sports Science as well as in Sports Medicine. This study aimed to develop and validate a prediction model for CRF based on a 45 second self-test, which can be conducted anywhere. Criterion validity, test re-test study was set up to accomplish our objectives. Data from 81 healthy volunteers (age: 29 ± 8 years, BMI: 24.0 ± 2.9), 18 of whom females, were used to validate this...

Data from: Pupillometry reveals perceptual differences that are tightly linked to autistic traits in typical adults

Marco Turi, David Charles Burr & Paola Binda
The pupil is primarily regulated by prevailing light levels, but is also modulated by perceptual and attentional factors. We measured pupil-size in typical adult humans viewing a bistable-rotating cylinder, constructed so the luminance of the front surface changes with perceived direction of rotation. In some participants, pupil diameter oscillated in phase with the ambiguous perception, more dilated when the black surface was in front. Importantly, the magnitude of oscillation predicts autistic traits of participants, assessed...

Data from: A pre-Miocene Irano-Turanian cradle: origin and diversification of the species-rich monocot genus Gagea (Liliaceae)

Angela Peterson, Dörte Harpke, Jens Peterson, Alexander Harpke & Lorenzo Peruzzi
The Irano‐Turanian (IT) floristic region is considered an important centre of origin for many taxa. However, there is a lack of studies dealing with typical IT genera that also occur in neighbouring areas. The species-rich monocot genus Gagea Salisb. shows a centre of diversity in IT region and a distribution in adjacent regions, therefore representing a good study object to investigate spatial and temporal relationships among IT region and its neighbouring areas (East-Asia, Euro-Siberia, Himalaya,...

Data from: Response to short-term deprivation of the human adult visual cortex measured with 7T BOLD

Paola Binda, Jan W. Kurzawski, Claudia Lunghi, Laura Biagi, Michela Tosetti & Maria Concetta Morrone
Sensory deprivation during the post-natal "critical period" leads to structural reorganization of the developing visual cortex. In adulthood, the visual cortex retains some flexibility and adapts to sensory deprivation. Here we show that short-term (2h) monocular deprivation in adult humans boosts the BOLD response to the deprived eye, changing ocular dominance of V1 vertices, consistent with homeostatic plasticity. The boost is strongest in V1, present in V2, V3 &V4 but absent in V3a and hMT+....

Data from: Rhythmic motor behavior influences perception of visual time

Alice Tomassini, Tiziana Vercillo, Francesco Torricelli & Maria Concetta Morrone
Temporal processing is fundamental for an accurate synchronization between motor behavior and sensory processing. Here we investigate how motor timing during rhythmic tapping influences perception of visual time. Participants listen to a sequence of four auditory tones played at 1 Hz and continue the sequence (without auditory stimulation) by tapping four times with their finger. During finger tapping, they are presented with an empty visual interval and are asked to judge its length compared to...

The extraterrestrial dust flux: size distribution and mass contribution estimates inferred from the Transantarctic Mountain (TAM) micrometeorite collection

Martin Suttle & Luigi Folco
This study explores the long-duration (0.8-2.3Ma), time-averaged micrometeorite flux (mass and size distribution) reaching Earth, as recorded by the Transantarctic Mountain (TAM) micrometeorite collection. We investigate a single sediment trap (TAM65), performing an exhaustive recovery and characterization effort and identifying 1643 micrometeorites (between 100-2000μm). Approximately 7% of particles are unmelted or scoriaceous, of which 75% are fine-grained. Among cosmic spherules, 95.6% are silicate-dominated S-types, and further subdivided into porphyritic (16.9%), barred olivine (19.9%), cryptocrystalline (51.6%)...

Combining conservation status and species distribution models for planning assisted colonisation under climate change

Gabriele Casazza, Thomas Abeli, Gianluigi Bacchetta, Davide Dagnino, Giuseppe Fenu, Domenico Gargano, Luigi Minuto, Chiara Montagnani, Simone Orsenigo, Lorenzo Peruzzi, Lucia Varaldo & Graziano Rossi
Effects of climate change are particularly important in the Mediterranean Biodiversity hotspot where rising temperatures and drought are negatively affecting several plant taxa, including endemic species. Assisted Colonisation (AC) represents a useful tool for reducing the effect of climate change on endemic plant species threatened by climate change. We combined SDMs for 188 taxa endemic to Italy with the IUCN red listing range loss threshold under criterion A (30%) to define: a) the number of...

Genome-wide markers redeem the lost identity of a heavily managed gamebird

Qian Tang, Giovanni Forcina, Qian Tang, Emilie Cros, Monica Guerrini, Frank Rheindt & Filippo Barbanera
Heavily managed wildlife may suffer from genetic homogenisation and reshuffling of locally adapted genotypes with non-native ones. This phenomenon often affects natural populations by reducing their evolutionary potential and speeding up the ongoing biodiversity crisis. For decades, the red-legged partridge (Alectoris rufa), an intensively managed gamebird of conservation concern and considerable socio-economic importance, has been subjected to extensive releases of farm-reared hybrids with the chukar partridge (A. chukar) and translocations irrespective of subspecific affinity. These...

AI3SD Video: Explainable Machine Learning for Trustworthy AI

Fosca Giannotti
Black box AI systems for automated decision making, often based on machine learning over (big) data, map a userâs features into a class or a score without exposing the reasons why. This is problematic not only for the lack of transparency, but also for possible biases inherited by the algorithms from human prejudices and collection artifacts hidden in the training data, which may lead to unfair or wrong decisions. The future of AI lies in...

Additional file 3 of The prognostic value of the previous nephrectomy in pretreated metastatic renal cell carcinoma receiving immunotherapy: a sub-analysis of the Meet-URO 15 study

Sara Elena Rebuzzi, Alessio Signori, Giuseppe Luigi Banna, Annalice Gandini, Giuseppe Fornarini, Alessandra Damassi, Marco Maruzzo, Ugo De Giorgi, Umberto Basso, Silvia Chiellino, Luca Galli, Paolo Andrea Zucali, Emanuela Fantinel, Emanuele Naglieri, Giuseppe Procopio, Michele Milella, Francesco Boccardo, Lucia Fratino, Stefania Pipitone, Riccardo Ricotta, Stefano Panni, Veronica Mollica, Mariella Sorarù, Matteo Santoni, Alessio Cortellini … & Sebastiano Buti
Additional file 3: Figure S3. Kaplan Meiers curves showing the prognostic role of nephrectomy in mRCC patients according to the type of nephrectomy.

Additional file 1 of Synaptic alterations in visual cortex reshape contrast-dependent gamma oscillations and inhibition-excitation ratio in a genetic mouse model of migraine

Nicolò Meneghetti, Chiara Cerri, Eleonora Vannini, Elena Tantillo, Angelita Tottene, Daniela Pietrobon, Matteo Caleo & Alberto Mazzoni
Fig. S1 related to Figs. 3, 4. (A) (left) PSD modulation for the minimum contrast level (K = 0) of experimental (black) and simulated data for WT (orange, left) and FHM1 (green, right). $${\chi}_r^2=0.34$$ χ r 2 = 0.34 for WT and $${\chi}_r^2=0.28$$ χ r 2 = 0.28 for FHM1. (B) Cortical narrow band power modulation as a function of thalamic narrow band strength in the FHM1 model. The model was set with (red) and...

Additional file 2 of Origin and destination attachment: study of cultural integration on Twitter

Jisu Kim, Alina Sîrbu, Fosca Giannotti, Giulio Rossetti & Hillel Rapoport
Table 4. Correlation table for OA & DA and Hofstede’s cultural dimension scores. (CSV 1 kB)

Rural landscapes of the 20th Century

Stefania Landi, Concetta Lenza & Denise Ulivieri

Data from: Age and sex prevalence estimate of Joubert Syndrome in Italy

Sara Nuovo, Ilaria Bacigalupo, Monia Ginevrino, Roberta Battini, Enrico Bertini, Renato Borgatti, Antonella Casella, Alessia Micalizzi, Marta Nardella, Romina Romaniello, Valentina Serpieri, Ginevra Zanni, Enza Maria Valente & Nicola Vanacore
Objective: To estimate the prevalence of Joubert syndrome (JS) in Italy applying standards of descriptive epidemiology, and to provide a molecular characterization of the described patients cohort. Methods: We enrolled all patients with a neuroradiologically confirmed diagnosis of JS and resident in Italy in 2018, and calculated age and sex prevalence, assuming a Poisson distribution. We also investigated the correlation between proband chronological age and age at diagnosis, and performed Next-Generation Sequencing (NGS) analysis on...

Codice Pelavicino. Edizione digitale

Enrica Salvatori, Edilio Riccardini, Roberto Rosselli del Turco, Laura Balletto, Chiara Alzetta, Chiara Di Pietro, Chiara Mannari, Raffaele Masotti & Alessio Miaschi
Edizione critica digitale del codice noto come Codice Pelavicino conservato presso l’Archivio Capitolare Lunense (Sarzana), manoscritto del XIII secolo, che contiene numerosi documenti dei secoli XI-XIII inerenti la Chiesa di Luni. Principale promotore della sua redazione fu il vescovo di Luni Enrico da Fucecchio, che salì al soglio episcopale nel 1273 e resignò la carica tra il 24 ottobre 1296 e l’inizio del 1297. Al fine di salvaguardare i beni e i diritti della Chiesa...

Additional file 1 of Synaptic alterations in visual cortex reshape contrast-dependent gamma oscillations and inhibition-excitation ratio in a genetic mouse model of migraine

Nicolò Meneghetti, Chiara Cerri, Eleonora Vannini, Elena Tantillo, Angelita Tottene, Daniela Pietrobon, Matteo Caleo & Alberto Mazzoni
Fig. S1 related to Figs. 3, 4. (A) (left) PSD modulation for the minimum contrast level (K = 0) of experimental (black) and simulated data for WT (orange, left) and FHM1 (green, right). $${\chi}_r^2=0.34$$ χ r 2 = 0.34 for WT and $${\chi}_r^2=0.28$$ χ r 2 = 0.28 for FHM1. (B) Cortical narrow band power modulation as a function of thalamic narrow band strength in the FHM1 model. The model was set with (red) and...

Synaptic alterations in visual cortex reshape contrast-dependent gamma oscillations and inhibition-excitation ratio in a genetic mouse model of migraine

Nicolò Meneghetti, Chiara Cerri, Eleonora Vannini, Elena Tantillo, Angelita Tottene, Daniela Pietrobon, Matteo Caleo & Alberto Mazzoni
Abstract Background Migraine affects a significant fraction of the world population, yet its etiology is not completely understood. In vitro results highlighted thalamocortical and intra-cortical glutamatergic synaptic gain-of-function associated with a monogenic form of migraine (familial-hemiplegic-migraine-type-1: FHM1). However, how these alterations reverberate on cortical activity remains unclear. As altered responsivity to visual stimuli and abnormal processing of visual sensory information are common hallmarks of migraine, herein we investigated the effects of FHM1-driven synaptic alterations in...

The prognostic value of the previous nephrectomy in pretreated metastatic renal cell carcinoma receiving immunotherapy: a sub-analysis of the Meet-URO 15 study

Sara Elena Rebuzzi, Alessio Signori, Giuseppe Luigi Banna, Annalice Gandini, Giuseppe Fornarini, Alessandra Damassi, Marco Maruzzo, Ugo De Giorgi, Umberto Basso, Silvia Chiellino, Luca Galli, Paolo Andrea Zucali, Emanuela Fantinel, Emanuele Naglieri, Giuseppe Procopio, Michele Milella, Francesco Boccardo, Lucia Fratino, Stefania Pipitone, Riccardo Ricotta, Stefano Panni, Veronica Mollica, Mariella Sorarù, Matteo Santoni, Alessio Cortellini … & Sebastiano Buti
Abstract Background Nephrectomy is considered the backbone of managing patients with localized and selected metastatic renal cell carcinoma (mRCC). The prognostic role of nephrectomy has been widely investigated with cytokines and targeted therapy, but it is still unclear in the immunotherapy era. Methods We investigated the Meet-URO-15 study dataset of 571 pretreated mRCC patients receiving nivolumab as second or further lines about the prognostic role of the previous nephrectomy (received in either the localized or...

Additional file 1 of The prognostic value of the previous nephrectomy in pretreated metastatic renal cell carcinoma receiving immunotherapy: a sub-analysis of the Meet-URO 15 study

Sara Elena Rebuzzi, Alessio Signori, Giuseppe Luigi Banna, Annalice Gandini, Giuseppe Fornarini, Alessandra Damassi, Marco Maruzzo, Ugo De Giorgi, Umberto Basso, Silvia Chiellino, Luca Galli, Paolo Andrea Zucali, Emanuela Fantinel, Emanuele Naglieri, Giuseppe Procopio, Michele Milella, Francesco Boccardo, Lucia Fratino, Stefania Pipitone, Riccardo Ricotta, Stefano Panni, Veronica Mollica, Mariella Sorarù, Matteo Santoni, Alessio Cortellini … & Sebastiano Buti
Additional file 1: Figure S1. Stratification of patients by IMDC score at disease onset and nivolumab treatment start (N = 493)*. * Missing data for 63 patients. Abbrevviations: PG prognostic group, RG risk group.

Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery

Miklosh Bala, Fausto Catena, Jeffry Kashuk, Belinda De Simone, Carlos Augusto Gomes, Dieter Weber, Massimo Sartelli, Federico Coccolini, Yoram Kluger, Fikri M. Abu-Zidan, Edoardo Picetti, Luca Ansaloni, Goran Augustin, Walter L. Biffl, Marco Ceresoli, Osvaldo Chiara, Massimo Chiarugi, Raul Coimbra, Yunfeng Cui, Dimitris Damaskos, Salomone Di Saverio, Joseph M. Galante, Vladimir Khokha, Andrew W. Kirkpatrick, Kenji Inaba … & Ernest E. Moore
Abstract Acute mesenteric ischemia (AMI) is a group of diseases characterized by an interruption of the blood supply to varying portions of the intestine, leading to ischemia and secondary inflammatory changes. If untreated, this process may progress to life-threatening intestinal necrosis. The incidence is low, estimated at 0.09–0.2% of all acute surgical admissions, but increases with age. Although the entity is an uncommon cause of abdominal pain, diligence is required because if untreated, mortality remains...

Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery

Miklosh Bala, Fausto Catena, Jeffry Kashuk, Belinda De Simone, Carlos Augusto Gomes, Dieter Weber, Massimo Sartelli, Federico Coccolini, Yoram Kluger, Fikri M. Abu-Zidan, Edoardo Picetti, Luca Ansaloni, Goran Augustin, Walter L. Biffl, Marco Ceresoli, Osvaldo Chiara, Massimo Chiarugi, Raul Coimbra, Yunfeng Cui, Dimitris Damaskos, Salomone Di Saverio, Joseph M. Galante, Vladimir Khokha, Andrew W. Kirkpatrick, Kenji Inaba … & Ernest E. Moore
Abstract Acute mesenteric ischemia (AMI) is a group of diseases characterized by an interruption of the blood supply to varying portions of the intestine, leading to ischemia and secondary inflammatory changes. If untreated, this process may progress to life-threatening intestinal necrosis. The incidence is low, estimated at 0.09–0.2% of all acute surgical admissions, but increases with age. Although the entity is an uncommon cause of abdominal pain, diligence is required because if untreated, mortality remains...

Data from: Network analysis of sea turtle movements and connectivity: a tool for conservation prioritization

Connie Y. Kot, Susanne Åkesson, Joanna Alfaro-Shigueto, Diego Fernando Amorocho Llanos, Marina Antonopoulou, George H. Balazs, Warren R. Baverstock, Janice M. Blumenthal, Annette C. Broderick, Ignacio Bruno, Ali Fuat Canbolat, Paolo Casale, Daniel Cejudo, Michael S. Coyne, Corrie Curtice, Sarah DeLand, Andrew DiMatteo, Kara Dodge, Daniel C. Dunn, Nicole Esteban, Angela Formia, Mariana M. P. B. Fuentes, Ei Fujioka, Julie Garnier, Matthew H. Godfrey … & Patrick N. Halpin
Aim: Understanding the spatial ecology of animal movements is a critical element in conserving long-lived, highly mobile marine species. Analysing networks developed from movements of six sea turtle species reveals marine connectivity and can help prioritize conservation efforts. Location: Global. Methods: We collated telemetry data from 1,235 individuals and reviewed the literature to determine our dataset’s representativeness. We used the telemetry data to develop spatial networks at different scales to examine areas, connections, and their...

Additional file 1 of Synergistic effect of chronic kidney disease, neuropathy, and retinopathy on all-cause mortality in type 1 and type 2 diabetes: a 21-year longitudinal study

Luca Sacchetta, Martina Chiriacò, Lorenzo Nesti, Simone Leonetti, Giovanna Forotti, Andrea Natali, Anna Solini & Domenico Tricò
Additional file 1: Table S1. Baseline characteristics of the subgroup of study participants fully characterized for the presence of CKD, CAN, and DR. Table S2. Baseline characteristics of the study participants fully characterized for the presence of CKD, CAN, and DR stratified by the number of MVC.

Registration Year

  • 2022
    39
  • 2021
    6
  • 2020
    15
  • 2019
    5
  • 2018
    6
  • 2017
    1
  • 2016
    6
  • 2015
    4
  • 2014
    1
  • 2013
    1

Resource Types

  • Dataset
    46
  • Text
    16
  • Collection
    10
  • Image
    6
  • Journal Article
    4
  • Audiovisual
    1
  • Other
    1

Affiliations

  • University of Pisa
    84
  • Azienda Ospedaliera Universitaria Pisana
    17
  • Scuola Normale Superiore di Pisa
    15
  • University of Florence
    14
  • University of Cagliari
    10
  • Ospedale di Parma
    10
  • University of Genoa
    9
  • Ospedale Santa Chiara
    8
  • Portsmouth Hospitals NHS Trust
    8
  • University of Bologna
    8