379 Works

Data from: Bayesian causal inference explains movement coordination to auditory beats

Mark T. Elliott, Alan M. Wing & Andrew E. Welchman
Many everyday skilled actions depend on moving in time with signals that are embedded in complex auditory streams (e.g. musical performance, dancing or simply holding a conversation). Such behaviour is apparently effortless; however, it is not known how humans combine auditory signals to support movement production and coordination. Here, we test how participants synchronize their movements when there are potentially conflicting auditory targets to guide their actions. Participants tapped their fingers in time with two...

Data from: Stable epigenetic effects impact adaptation in allopolyploid orchids (Dactylorhiza: Orchidaceae)

Ovidiu Paun, Richard M. Bateman, Michael F. Fay, Mikael Hedrén, Laure Civeyrel & Mark W. Chase
Epigenetic information includes heritable signals that modulate gene expression but are not encoded in the primary nucleotide sequence. We have studied natural epigenetic variation in three allotetraploid sibling orchid species that differ radically in geography/ecology. The epigenetic variation released by genome doubling has been restructured in species-specific patterns that reflect their recent evolutionary history, and have an impact on their ecology and evolution, hundreds of generations after their formation. Epigenome scans pinpointed epiloci under divergent...

Data from: Competition and constraint drove Cope's rule in the evolution of giant flying reptiles

Roger B. J. Benson, Rachel A. Frigot, Anjali Goswami, Brian Andres & Richard J. Butler
The pterosaurs, Mesozoic flying reptiles, attained wingspans of more than 10 m that greatly exceed the largest birds and challenge our understanding of size limits in flying animals. Pterosaurs have been used to illustrate Cope’s rule, the influential generalization that evolutionary lineages trend to increasingly large body sizes. However, unambiguous examples of Cope’s rule operating on extended timescales in large clades remain elusive, and the phylogenetic pattern and possible drivers of pterosaur gigantism are uncertain....

Data from: How innovative are new drugs launched in the UK? A retrospective study of new drugs listed in the British National Formulary (BNF) 2001-2012

Derek J. Ward, Angharad Slade, Tracey Genus, Orsolina I. Martino & Andrew J. Stevens
Objectives: Innovative new drugs offer potential benefits to patients, healthcare systems, governments and the pharmaceutical industry. Recent data suggest annual numbers of new drugs launched in the UK have increased in recent years, and we sought to understand whether this represents increasing numbers of highly innovative drugs being made available or the introduction of increasing numbers of drugs with limited additional therapeutic value. Design and setting: Retrospective observational study of new drug entries in the...

Data from: Lesions to right posterior parietal cortex impair visual depth perception from disparity but not motion cues

Aidan P. Murphy, David A. Leopold, Glyn W. Humphreys & Andrew E. Welchman
The posterior parietal cortex (PPC) is understood to be active when observers perceive three-dimensional (3D) structure. However, it is not clear how central this activity is in the construction of 3D spatial representations. Here, we examine whether PPC is essential for two aspects of visual depth perception by testing patients with lesions affecting this region. First, we measured subjects' ability to discriminate depth structure in various 3D surfaces and objects using binocular disparity. Patients with...

Data from:Spatio-temporal networks: reachability, centrality and robustness

Matthew J. Williams & Mirco Musolesi
Recent advances in spatial and temporal networks have enabled researchers to more-accurately describe many real-world systems such as urban transport networks. In this paper, we study the response of real-world spatio-temporal networks to random error and systematic attack, taking a unified view of their spatial and temporal performance. We propose a model of spatio-temporal paths in time-varying spatially embedded networks which captures the property that, as in many real-world systems, interaction between nodes is non-instantaneous...

Field measurements of alkalinity, chloride-ion, conductivity, pH and nutrients in rivers (2003-2006) [LOCAR]

D. Leach, P. Henville, R. Wyatt, E. Hewitt, I. Morrissey, J. Weller, C. I. Tindall & N. Bachiller-Jareno
River water alkalinity, chloride-ion, conductivity, pH and nutrients data from the Frome Piddle; Pang Lambourn and Tern catchments, recorded between 2003 and 2006. River water samples were collected fortnightly at twenty three sites within these catchments and analysed for Alkalinity pH 4.5, Ammonia, Chloride-ion, Conductivity 20 deg C, Nitrate, pH, Phosphorus soluble reactive (SRP), Silicate reactive dissolved (SRD) and Sulphate. The samples were collected as part of the NERC funded Lowland Catchment Research (LOCAR) Programme...

Data from: The genomic landscape of rapid repeated evolutionary adaptation to toxic pollution in wild fish

Noah M. Reid, Dina A. Proestou, Bryan W. Clark, Wesley C. Warren, John K. Colbourne, Joseph R. Shaw, Sibel I. Karchner, Mark E. Hahn, Diane Nacci, Marjorie F. Oleksiak, Douglas L. Crawford & Andrew Whitehead
Atlantic killifish populations have rapidly adapted to normally lethal levels of pollution in four urban estuaries. Through analysis of 384 whole killifish genome sequences and comparative transcriptomics in four pairs of sensitive and tolerant populations, we identify the aryl hydrocarbon receptor–based signaling pathway as a shared target of selection. This suggests evolutionary constraint on adaptive solutions to complex toxicant mixtures at each site. However, distinct molecular variants apparently contribute to adaptive pathway modification among tolerant...

Data from: Drought intensification drives turnover of structure and function in stream invertebrate communities

Thomas W.H. Aspin, Thomas J. Matthews, Kieran Khamis, Alexander M. Milner, Zining Wang, Matthew J. O'Callaghan, Mark E. Ledger & Thomas W. H. Aspin
Climatic extremes are becoming more frequent and intense across much of the globe, potentially transforming the biodiversity and functioning of affected ecosystems. In freshwaters, hydrological extremes such as drought can regulate beta diversity, acting as powerful environmental filters to dictate the complement of species and functional traits found at local and landscape scales. New methods that enable beta diversity and its functional equivalent to be partitioned into turnover (replacement of species/functions) and nestedness-resultant (gain/loss of...

Data from: Differential temporal beta-diversity patterns of native and non-native arthropod species in a fragmented native forest landscape

Tom Matthews, Jon P. Sadler, Rui Carvalho, Rui Nunes, Paulo A.V. Borges, Thomas J. Matthews & Jon Sadler
An important factor that hinders the management of non-native species is a general lack of information regarding the biogeography of non-natives, and, in particular, their rates of turnover. Here, we address this research gap by analysing differences in temporal beta-diversity (using both pairwise and multiple-time dissimilarity metrics) between native and non-native species, using a novel time-series dataset of arthropods sampled in native forest fragments in the Azores. We use a null model approach to determine...

Data from: Flexibility, variability and constraint in energy management strategies across vertebrate taxa revealed by long-term heart rate measurements

Lewis G. Halsey, Jonathan A. Green, Sean D. Twiss, Walter Arnold, Sarah J. Burthe, Patrick J. Butler, Steve J. Cooke, David Gremillet, Thomas Ruf, Olivia Hicks, Katarzyna J. Minta, Tanya S. Prystay, Claudia A.F. Wascher, Vincent Careau, Steven J Cooke, Tania S Prystay & Claudia AF Wascher
1) Animals are expected to be judicious in the use of the energy they gain due to the costs and limits associated with its intake. The management of energy expenditure (EE) exhibited by animals has previously been considered in terms of three patterns: the constrained, independent and performance patterns of energy management. These patterns can be interpreted by regressing daily EE against maintenance EE measured over extended periods. From the multiple studies on this topic,...

Rates of fluorescein diacetate hydrolysis, phenol oxidation and potential denitrification in sand and gravel sediments from an agriculturally-impacted stream

S. Ullah, L. Glover & A. Percival
The dataset contains measurements of fluorescein, dopachrome and nitrous oxide production from incubation experiments of streambed sediments. The sediments were collected in five pseudo-replicates from 0 to 10cm depth using a 5cm-diameter AMS slide hammer and trowel at two locations within the Wood Brook, Staffordshire, in June 2015. Samples were collected from two reaches within the stream, a mid-stream sandy reach and a downstream gravel reach. The sediment was used in laboratory incubation experiments to...

Data from: Resilience or robustness: identifying topological vulnerabilities in rail networks

Alessio Pagani, Guillem Mosquera, Aseel Alturki, Samuel Johnson, Stephen Jarvis, Alan Wilson, Weisi Guo & Liz Varga
Many critical infrastructure systems have network structure and are under stress. Despite their national importance, the complexity of large-scale transport networks means we do not fully understand their vulnerabilities to cascade failures. The research in this paper examines the interdependent rail networks in Greater London and surrounding commuter area. We focus on the morning commuter hours, where the system is under the most demand stress. There is increasing evidence that the topological shape of the...

Data from: Trajectories of motor abnormalities in milder phenotypes of ataxia telangiectasia

Nienke J.H. Van Os, Anke Hensiek, Judith Van Gaalen, Alexander M.R. Taylor, Marcel Van Deuren, Corry M.R. Weemaes, Michel A.A.P. Willemsen & Bart P.C. Van De Warrenburg
Objective: To describe and classify the neurological trajectories in patients with mild neurological forms of ataxia telangiectasia (A-T) from the Dutch A-T cohort, combined with patients reported in the literature. Methods: Clinical, genetic and laboratory data of 14 A-T patients with mild neurological phenotypes from the Dutch cohort were analyzed and combined with corresponding data from the literature. A mild neurological phenotype was defined by a later onset, non-ataxia presenting or dominant feature, or slower...

Connected clusters: landscaping study

Gavin Harper

Raw capture spectral JPEG images of Codex Zacynthius

David Parker, Hugh Houghton & Michael Phelps
This dataset consists of the images of Codex Zacynthius (Cambridge, University Library, MS Add. 10062) captured using multi-spectral and x-ray photography in July 2018. The images were taken by the Early Manuscripts Electronic Library (EMEL), working on behalf of the Codex Zacynthius Project, funded by the Arts and Humanities Research Council. There are 51 images for each page. Details of the settings of each image (wavelength etc.) are provided in the filenames. One folder of...

A Transcription of the Lectionary of Codex Zacynthius

Amy Myshrall, Gavriil-Ioannis Boutziopoulos, Thomas William Ruston, Hugh Houghton & Catherine Smith
The file attached to this record is a transcription of Codex Zacynthius (Cambridge, University Library, MS Add. 10062; Gregory-Aland L299). It was made from colour digital images by members of the Codex Zacynthius Project in 2018–2020, using the Online Transcription Editor in the Workspace for Collaborative Editing. The XML encoding follows the TEI P5 Guidelines. Further details are provided in the TEI header of the file. This transcription is made available under a Creative Commons...

Low Temperature Synthesis of Garnet Solid State Electrolytes: implications on aluminium incorporation in Li7La3Zr2O12

Bo Dong, Laura Driscoll, Mark Stockham, Emma Kendrick & Peter Slater
XRD patterns of Li7La3Zr2O12, Al or Zn doped Li7La3Zr2O12, Li6.55Al0.15La3Zr2O12.

Kinetics of vanillin hydrodeoxygenation reaction in an organic solvent using a Pd/C catalyst

Elias Aliu, Abarasi Hart & Joseph Wood
Kinetics of vanillin hydrodeoxygenation reaction in an organic solvent using a Pd/C catalyst

Digital Surface Models for the South Saskatchewan River, Canada

P. Ashworth, A. Nicholas, D. Parsons & G. Sambrook Smith
Data were collected in 2015, 2016 and 2017 to provide Digital Surface Models (DSM) for two sections of the South Saskatchewan River, Canada. DSMs were generated using aerial plane images with a 0.06m ground resolution, captured at a height of c. 1500 m from a fixed-wing aeroplane with an UltraCamXp sensor. DSMs were generated as part of NERC project NE/L00738X/1. DSMs were constructed using imagery obtained on four occasions (13th May 2015; 2nd Sept 2016;...

Data to accompany \"Probing the fundamentals of native liquid extraction surface analysis mass spectrometry of proteins: Can proteins refold during extraction? \"

Helen Cooper
Data to accompany "Probing the fundamentals of native liquid extraction surface analysis mass spectrometry of proteins: Can proteins refold during extraction? "

Using peridynamics and discrete multiphysics to study the effects of air voids and freezing water on the mechanical properties of asphalt

Danillo Sanfilippo, Ghiassi Bahman, Alessio Alexiadis & Alvaro Garcia Hernandez

MISL Measurement Campaign for the project CORTEX (Cognitive Real-Time System for Autonomous Vehicles)

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The dataset contains data collected by the the MISL (Microwave Integrated Systems Laboratory) group at the University of Birmingham, for the project CORTEX (Cognitive Real-Time System for Autonomous Vehicles), which is funded by Innovate UK. The objectives of the CORTEX project are to provide novel sensing technology, robust in all-weather and all-road conditions, to support the delivery of L4/5 autonomy, using advanced sensor fusion, tracking and cognitive radar techniques.

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