Abstract Background Clinical psychomotor skills training is a core component of undergraduate nursing education. Performing technical skills competently involves the use of cognitive and motor function. The training of these technical skills is typically carried out in clinical simulation laboratories. Peripheral intravenous catheter/cannula insertion is an example of a technical skill. It is the most common invasive procedure performed in the healthcare environment. Owing to unacceptable clinical risk and complications to patients, it is imperative...

Abstract Background Mesenchymal stromal cells (MSCs), commonly sourced from adipose tissue, bone marrow and umbilical cord, have been widely used in many medical conditions due to their therapeutic potential. Yet, the still limited understanding of the underlying mechanisms of action hampers clinical translation. Clinical potency can vary considerably depending on tissue source, donor attributes, but importantly, also culture conditions. Lack of standard procedures hinders inter-study comparability and delays the progression of the field. The aim...

Additional file 3: Supplementary Fig. S3. Representative phase contrast images of MSCs in all sites at earlyand latestages of culture. Pictures taken at 100X; scale bar 200 µm.

Additional file 5: Supplementary Fig. S5. Representative phase contrast images of MSC at the end of the adipogenicand osteogenicdifferentiation procedure in comparison with undifferentiated culturesin each site. Pictures taken at 100X; scale bar 200 µm.

Additional file 6: Supplementary Fig. S6. Angiogenic and wound healing properties of MSCs listed by donor.Number of tubules, junctionsand closed loopsgenerated by each donor. Data expressed as a fold-change of the positive control; mean ± SD, n = 3.Differential angiogenic proteomic profile detected for A-, BM-and UC-MSCs. Data expressed as fold change of the internal reference spots.Wound closure induced by each donor per cell source at 8 and 24 hours. Data displayed as mean ±...

Background Delirium is extremely prevalent, yet underdiagnosed, in older patients and is associated with prolonged length of hospital stay and higher mortality rates. Impaired attention is the cardinal defcit in delirium and is a required feature in diagnostic criteria. The verbal months backwards test (MBT) is the most sensitive bedside test of attention, however, hospital staf occasionally have difculty with its administration and interpretation. We hypothesise that the MBT on an electronic tablet may be...

Supplemental material, sj-docx-4-dhj-10.1177_20552076231170696 for Development of a video-based evidence synthesis knowledge translation resource: Drawing on a user-centred design approach by Cristian Deliv, Declan Devane, El Putnam, Patricia Healy, Amanda Hall, Sarah Rosenbaum and Elaine Toomey in DIGITAL HEALTH

Supplemental material, sj-docx-1-dhj-10.1177_20552076231170696 for Development of a video-based evidence synthesis knowledge translation resource: Drawing on a user-centred design approach by Cristian Deliv, Declan Devane, El Putnam, Patricia Healy, Amanda Hall, Sarah Rosenbaum and Elaine Toomey in DIGITAL HEALTH

Food systems are responsible for one third of global greenhouse gas (GHG) emissions. Dairy production is a significant contributor to those emissions and, given that global demand for dairy is projected to increase, there is an urgent need to reduce emissions from this sector. For example, a clearer understanding of the functioning and acceptability of climate-smart innovations that can be implemented along the dairy supply chain can contribute to achieving a climate-neutral EU continent by...

Rapidly increasing heavy metal waste has adversely affected the environment and the Earth’s health. The lack of appropriate remediation technologies has worsened the issue globally, especially in developing countries. Heavy-metals contaminants have severely impacted the environment and led to devastating conditions owing to their abundance and reactivity. As they are nondegradable, the potential risk increases even at a low concentration. However, heavy-metal remediation has increased with the up-gradation of technologies and integration of new approaches....

Background: Population ageing is increasing rapidly worldwide. Older adults are frequent users of health care services including the Emergency Department (ED) and experience a number of adverse outcomes following an ED visit. Adverse outcomes include functional decline, unplanned hospital admission and an ED revisit. Given these adverse outcomes a number of interventions have been examined to improve the outcomes of older adults following presentation to the ED. The aim of this umbrella review was to...

Background: Irreversible electroporation has emerged as a new modality to overcome issues associated with other energy sources for cardiac ablation. Strong evidence on the optimal, effective, and selective voltage threshold is lacking for both in vitro and preclinical in vivo studies. The aim of this study is to examine the optimal threshold for selective cell ablation on cardiac associated cell types. Methods: Conventional monophasic and biphasic pulses of different field strength were delivered in a...

Background: Irreversible electroporation has emerged as a new modality to overcome issues associated with other energy sources for cardiac ablation. Strong evidence on the optimal, effective, and selective voltage threshold is lacking for both in vitro and preclinical in vivo studies. The aim of this study is to examine the optimal threshold for selective cell ablation on cardiac associated cell types. Methods: Conventional monophasic and biphasic pulses of different field strength were delivered in a...