36 Works

Relationship of total and calculated free 25-hydroxyvitamin D to biomarkers and metabolic indices in healthy children

Christine Simpson, Jane Zhang, Dirk Vanderschueren, Lei Fu, Teresita Pennestri, Roger Bouillon, David Cole & Thomas Carpenter
ABSTRACT Context: Vitamin D status is usually assessed by serum total 25-hydroxyvitamin D. Whether free 25-hydroxyvitamin D measures better correlate with various clinical outcomes is unclear. Objective: To identify correlations between total 25-hydroxyvitamin D (t25-OHD), calculated and direct measures of free 25-OHD, and to identify associations of these measures with other outcomes in children, across the 6 common GC haplotypes. Design: Healthy urban-dwelling children underwent measurement of relevant variables. Setting: Academic medical center Participants: Healthy,...

Data from: Testing for local adaptation in adult male and female fitness among populations evolved under different mate competition regimes

Li Yun, Malak Bayoumi, Seon Yang, Patrick J. Chen, Howard D Rundle & Aneil F. Agrawal
Mating/fertilization success and fecundity are influenced by sexual interactions among individuals, the nature and frequency of which can vary among different environments. The extent of local adaptation for such adult fitness components is poorly understood. We allowed 63 populations of Drosophila melanogaster to independently evolve in one of three mating environments that alter sexual interactions: one involved enforced monogamy while the other two permitted polygamy in either structurally simple standard fly vials or in larger...

Data from: Whole-genome analyses resolve the phylogeny of flightless birds (Palaeognathae) in the presence of an empirical anomaly zone

Alison Cloutier, Timothy B. Sackton, Phil Grayson, Michele Clamp, Allan J. Baker & Scott V. Edwards
Palaeognathae represent one of the two basal lineages in modern birds, and comprise the volant (flighted) tinamous and the flightless ratites. Resolving palaeognath phylogenetic relationships has historically proved difficult, and short internal branches separating major palaeognath lineages in previous molecular phylogenies suggest that extensive incomplete lineage sorting (ILS) might have accompanied a rapid ancient divergence. Here, we investigate palaeognath relationships using genome-wide data sets of three types of noncoding nuclear markers, together totalling 20,850 loci...

Data from: Evaluating population genomic candidate genes underlying flowering time in Arabidopsis thaliana using T-DNA insertion lines

Veronica K. Chong & John R. Stinchcombe
Population genomic scans have emerged as a powerful tool to detect regions of the genome that are potential targets of selection. Despite the success of genomic scans in identifying novel lists of loci potentially underlying adaptation, few studies proceed to validate the function of these candidate genes. In this study, we used T-DNA insertion lines to evaluate the effects of 27 candidate genes on flowering time in North American accessions of Arabidopsis thaliana. We compared...

Data from: No consistent effects of humans on animal genetic diversity worldwide

Katie Millette, Vincent Fugère, Chloé Debyser, Ariel Greiner, Frédéric Chain & Andrew Gonzalez
Human impacts on genetic diversity are poorly understood yet critical to biodiversity conservation. We used 175,247 COI sequences collected between 1980 and 2016 to assess the global effects of land use and human density on the intraspecific genetic diversity of 17,082 species of birds, fishes, insects, and mammals. Human impacts on mtDNA diversity were taxon and scale-dependent, and were generally weak or non-significant. Spatial analyses identified weak latitudinal diversity gradients as well as negative effects...

Importance of spatio-temporal connectivity to maintain species experiencing range shifts

Jun-Long Huang, Marco Andrello, Alexandre Martensen, Santiago Saura, Dian-Feng Liu, Jian-Hua He & Marie-Josée Fortin
Climate change can affect the habitat resources available to species by changing habitat quantity, suitability and spatial configuration, which largely determine population persistence in the landscape. In this context, dispersal is a central process for species to track their niche. Assessments of the amount of reachable habitat (ARH) using static snap-shots do not account, however, for the temporal overlap of habitat patches that may enhance stepping-stone effects. Here, we quantified the impacts of climate change...

Expression atlas of Selaginella moellendorffii provides insights into the evolution of vasculature, secondary metabolism and roots

Camilla Ferrari, Devendra Shivhare, Bjoern Oest Hansen, Asher Pasha, Eddi Esteban, Nicholas J. Provart, Friedrich Kragler, Alisdair Fernie, Takayuki Tohge & Marek Mutwil
Selaginella moellendorffii is a representative of the lycophyte lineage and is studied to understand the evolution of land plant traits such as the vasculature, leaves, stems, roots, and secondary metabolism. However, only few studies investigated about the gene expression and transcriptional coordination of Selaginella genes, precluding us from understanding the evolution of transcriptional programs behind these traits. We present a gene expression atlas comprising all major organs, tissue types, and the diurnal gene expression profiles...

Data from: Integrating over uncertainty in spatial scale of response within multispecies occupancy models yields more accurate assessments of community composition

Luke Frishkoff, D. Mahler & Marie-Josee Fortin
Species abundance and community composition are affected not only by the local environment, but also by broader landscape and regional context. Yet, determining the spatial scales at which landscapes affect species remains a persistent challenge, hindering our ability to understand how environmental gradients shape communities. This problem is amplified by data deficient species and imperfect species detection. Here, we present a Bayesian framework that allows uncertainty surrounding the “true” spatial scale of species’ responses (i.e.,...

Genetic structure and biogeographic history of the Bicknell’s Thrush/ Gray-cheeked Thrush species complex

Alyssa FitzGerald, Jason Weir, Joel Ralston, Ian Warkentin, Darroch Whitaker & Jeremy Kirchman
Abstract We examined species limits, admixture, and genetic structure among populations in the Bicknell’s Thrush (Catharus bicknelli)–Gray-cheeked Thrush (C. minimus) species complex to establish the geographic and temporal context of speciation in this group, which is a model system in ecology and a high conservation priority. We obtained mitochondrial ND2 sequences from 186 Bicknell’s Thrushes, 77 Gray-cheeked Thrushes, and 55 individuals of their closest relative, the Veery (C. fuscescens), and genotyped a subset of individuals...

Data from: Experimental dominant plant removal results in contrasting assembly for dominant and non‐dominant plants

Carlos Alberto Arnillas & Marc W. Cadotte
Understanding why communities appear deterministically dominated by relatively few species is an age‐old debate in ecology. We hypothesised that the dominant and non‐dominant species in a community are governed by different assembly mechanisms where environmental conditions influence dominant species more than non‐dominant species. Further, dominant plants moderate the environment where non‐dominant species thrive, diminishing the influence of environmental filtering and increasing the influence of limiting similarity for non‐dominant species. We tested these hypotheses by removing...

Data from: Soil microbes alter plant fitness under competition and drought

Connor Fitzpatrick, Zainab Mustafa & Joani Viliunas
Plants exist across varying biotic and abiotic environments, including variation in the composition of soil microbial communities. The ecological effects of soil microbes on plant communities are well known, whereas less is known about their importance for plant evolutionary processes. In particular, the net effects of soil microbes on plant fitness may vary across environmental contexts and among plant genotypes, setting the stage for microbially mediated plant evolution. Here we assess the effects of soil...

Registration Year

  • 2019

Resource Types

  • Dataset


  • University of Toronto
  • Federal University of São Carlos
  • University of California, Berkeley
  • McGill University
  • University of Leeds
  • University of British Columbia
  • Harvard University
  • Royal Museum for Central Africa
  • Oeko Institut
  • University of Montana