Beta-actin (ACTB), a highly conserved cytoskeleton structural protein, has been regarded as a common housekeep gene and used as a reference gene for years. However, accumulating evidence indicates that ACTB is abnormally expressed in multiple cancers and hence changes the cytoskeleton to affect the invasiveness and metastasis of tumors. This study aimed to investigate the function and clinical significance of ACTB in pan-cancer. The role of ACTB for prognosis and immune regulation across 33 tumors...

Metadata, etc. for Krems et al. (in press). Sexually unrestricted women are perceived as having low self-esteem: First evidence for a pervasive, robust (but unfounded) stereotype. Psychological Science.

Understanding the biodiversity-productivity relationship and underlying mechanisms in natural ecosystems under realistic diversity loss scenarios remains a major challenge for ecologists despite its importance for predicting impacts of rapid loss of biodiversity worldwide. Here we report the results of a plant functional group (PFG) removal experiment conducted on the Mongolian Plateau, the largest remaining natural grassland in the world. Our results demonstrated that the biodiversity-productivity relationship varied among positive linear, neutral, and unimodal forms under...

Human beings are adept at generalizing linguistic patterns from their surrounding environments. For instance, infants as early as 6-8 month old are equipped of perceiving all sounds, while they experience perceptual narrowing to constrain the perception specific to the linguistic features of their native languages by 8-12-month old (Japanese infants no longer perceive the “r”-”l” contrast due to the absence of “r” in the Japanese linguistic inventory) (Kuhl et al., 2006). Previous literature suggests mixed...

The current research aims to explore the effect of message congruency on low-carbon behaviour. More specifically, it will be studied whether gain or loss frames are more effective when combined with a message construal that stimulates similar information processing. Besides this, it will be explored if processing fluency mediates this hypothesised effect, and if environmental concern moderates the relationship of processing fluency on low-carbon behaviour. The outcome of this study contributes to existing theory in...

A study to test whether people successfully draw implications from false facts when those facts are presented as true.

We will conduct a systematic review of family process and parenting correlates of sexual and gender minority youth health, mental health, and academic outcomes. The aims of the study are as follows: (1) Characterize the literature based on how much ethnoracial representation & sexual and gender minority identities representation (e.g., lesbian, gay, bisexual, questioning, transgender, gender nonconforming). (2) Examine what are the general, ethnoracial, & SGM-specific parenting practices/family processes variables that are related to the...

The claim selected for replication from Gabriel et al (2011) is: The impact of task accomplishment satisfaction on changes in daily affect is larger for direct care nursing tasks than for indirect care nursing tasks. This reflects the following from the paper’s abstract: “[W]e expected that task accomplishment satisfaction (or lack thereof) for these tasks would have stronger effects on changes in affect than would task accomplishment satisfaction for indirect care tasks.” The claim was...

This experiment explores the idea of sound symbolism (i.e., the phenomenon that different language sounds tend to reflect different meanings). In this case, the idea that different phonemes have different affective associations. Specifically, /^/ (as in "glum") is associated with negative affect whereas /i:/ (as in "gleam") is associated with positive affect. Our recent findings have established that people perceive /^/ words as more emotionally negative than /i:/ words (which we have named the gleam-glum...

Dryland (arid and semi-arid) ecosystems globally provide more than half of livestock production and store roughly one-third of soil organic carbon (SOC). Biogeochemical pools are changing due toshrub encroachment, livestock grazing, and climate change. We assessed how vegetation microsite, grazing, and precipitation interacted to affect SOC and total nitrogen (TN) at a site with long-term grazing manipulations and well-described patterns of shrub encroachment across elevation and mean annual precipitation (MAP) gradients. We analyzed SOC and...

A new aromatic glycoside (1) and twelve (2–13) known aromatic glycosides were isolated from the n-butyl alcohol of the 70% EtOH extract of the aerial part of Bupleurum chinense. Among them, compounds 4–7, 9, 11–13 were isolated from Umbelliferae plants for the first time. Their structures were elucidated by NMR and MS spectroscopy, and the absolute configuration of compound 1 was elucidated by single-crystal X-ray diffraction. Compounds 6 and 10 showed moderate cytotoxic activities on...

Beta-actin (ACTB), a highly conserved cytoskeleton structural protein, has been regarded as a common housekeep gene and used as a reference gene for years. However, accumulating evidence indicates that ACTB is abnormally expressed in multiple cancers and hence changes the cytoskeleton to affect the invasiveness and metastasis of tumors. This study aimed to investigate the function and clinical significance of ACTB in pan-cancer. The role of ACTB for prognosis and immune regulation across 33 tumors...

In this first study we aim to test whether a) people experience greater dispositional empathetic distress towards friends and kin, compared to acquaintances, b) whether people experience greater state-level empathetic distress when the target in distress is positively interdependent or biologically related, c) and whether ability to regulate one's emotions is negatively associated with both dispositional and state-level empathetic distress.

Tracking changes in belief during people's deliberations.