301 Works

The sustainable development of coal mines by new cutting roof technology

Yang Tai, Bin Yu, Rui Gao, Qiangling Yao, Zhao Li & Hongchun Xia
China consumes more than 3.6 billion tons of coal every year, accounting for over 60% of the energy consumption. Therefore, the sustainable development of coal mine is a problem needed to be solved by the Chinese government. During the coal resources recovery, the protective coal pillars between the adjacent working faces cause the serious loss for coal resources. In order to solve the problem, it was put forward that the new technology of roof cutting...

MOF-derived multi-interface carbon-based composites with enhanced polarization loss and efficient microwave absorption

Hongjiao Qu, Peng Zheng, Tao Wang, Xingyu Yu, Junjie Pan, Xiaoli Fan, Tengfei Zhang, Xin Sun & Jianping He
Metal-organic framework materials (MOFs) have been widely studied because of their adjustable composition and controllable structure in the field of microwave absorption (MA). Therein, Prussian blue analogs (PBA) have attracted the attention of researchers with ultra-high metal content. However, the attenuation ability of microwave for PBA-based composites is still unsatisfactory up to now. Therefore, the NiFe/CoFe@C composites were prepared by carbonizing polymetallic PBA (NiCoFe PBA) materials in this work, and the influence of different metal...

Spatial transcriptome profiling of human liver

shizhe yu, Haoren Wang, Lingpeng Yang, Yingxue Yan, Qiang Cai, Duo Ma, Jian Zhao, Long Jiang, Zehai Gao, Zhiyong Yu & Zongping Xia
This dataset contains a spatial transcriptome dataset of normal human liver. It contains code, raw data after space ranger processing, and integrated .rdata data.

Additional file 1 of Botulinum toxin treatment for bielschowsky acquired comitant esotropia in adults

Likun Ai, Xiaoli Chen, Ruilin Guo, Jing Li, Jinghui Wang, Yi Feng, Yiqin Guo & Jianan Wang
Supplementary Material 1

Supplemental Material, sj-doc-1-ear-10.1177_0145561320974863 - Primary Heterotopic Meningioma of Nasal Cavity: Case Report and Literature Review

Xianwen Hu, Maoyan Jiang, Zelong Feng, Juan Wang, Pan Wang & Jiong Cai
Supplemental Material, sj-doc-1-ear-10.1177_0145561320974863 for Primary Heterotopic Meningioma of Nasal Cavity: Case Report and Literature Review by Xianwen Hu, Maoyan Jiang, Zelong Feng, Juan Wang, Pan Wang and Jiong Cai in Ear, Nose & Throat Journal

Neomorphic DNA-binding enables tumor-specific therapeutic gene expression in fusion-addicted childhood sarcoma

Tilman L. B. Hölting, Florencia Cidre-Aranaz, Dana Matzek, Bastian Popper, Severin J. Jacobi, Cornelius M. Funk, Florian H. Geyer, Jing Li, Ignazio Piseddu, Bruno L. Cadilha, Stephan Ledderose, Jennifer Zwilling, Shunya Ohmura, David Anz, Annette Künkele, Frederick Klauschen, Thomas G. P. Grünewald & Maximilian M. L. Knott
Abstract Chimeric fusion transcription factors are oncogenic hallmarks of several devastating cancer entities including pediatric sarcomas, such as Ewing sarcoma (EwS) and alveolar rhabdomyosarcoma (ARMS). Despite their exquisite specificity, these driver oncogenes have been considered largely undruggable due to their lack of enzymatic activity. Here, we show in the EwS model that – capitalizing on neomorphic DNA-binding preferences – the addiction to the respective fusion transcription factor EWSR1-FLI1 can be leveraged to express therapeutic genes....

Additional file 4 of Metabolic engineering of Escherichia coli BW25113 for the production of 5-Aminolevulinic Acid based on CRISPR/Cas9 mediated gene knockout and metabolic pathway modification

Changchuan Ye, Yuting Yang, Xi Chen, Lijie Yang, Xia Hua, Mengjie Yang, Xiangfang Zeng & Shiyan Qiao
Additional file 4: Fig S4. Schematic illustration of DSB induction and homologous recombination. After preparing competent cells, the pTarget-gene and Donor DNA which harbored homology arms (HRR and HRL) that targeted a chromosomal locus spanning the middle of targeted gene and the DSB site were electroporated into cells.

Additional file 4 of Metabolic engineering of Escherichia coli BW25113 for the production of 5-Aminolevulinic Acid based on CRISPR/Cas9 mediated gene knockout and metabolic pathway modification

Changchuan Ye, Yuting Yang, Xi Chen, Lijie Yang, Xia Hua, Mengjie Yang, Xiangfang Zeng & Shiyan Qiao
Additional file 4: Fig S4. Schematic illustration of DSB induction and homologous recombination. After preparing competent cells, the pTarget-gene and Donor DNA which harbored homology arms (HRR and HRL) that targeted a chromosomal locus spanning the middle of targeted gene and the DSB site were electroporated into cells.

Visualization 1

Hong Zhao, Qingkang Bao, Jian Li, Xufeng Li, Tianyu Zhang & Chunwei Zhang
Dynamic 3D measurement based on orthogonal fringe projection and geometric constraints

sj-xlsx-2-tct-10.1177_15330338221124658 - Supplemental material for In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells

Mike Y. Chen, Jing Li, Nianli Zhang, Erik I. Waldorff, James T. Ryaby, Philip Fedor, Yongsheng Jia & Yujun Wang
Supplemental material, sj-xlsx-2-tct-10.1177_15330338221124658 for In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells by Mike Y. Chen, Jing Li, Nianli Zhang and Erik I. Waldorff, James T. Ryaby, Philip Fedor, Yongsheng Jia, Yujun Wang in Technology in Cancer Research & Treatment

sj-xlsx-3-tct-10.1177_15330338221124658 - Supplemental material for In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells

Mike Y. Chen, Jing Li, Nianli Zhang, Erik I. Waldorff, James T. Ryaby, Philip Fedor, Yongsheng Jia & Yujun Wang
Supplemental material, sj-xlsx-3-tct-10.1177_15330338221124658 for In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells by Mike Y. Chen, Jing Li, Nianli Zhang and Erik I. Waldorff, James T. Ryaby, Philip Fedor, Yongsheng Jia, Yujun Wang in Technology in Cancer Research & Treatment

Additional file 1 of 5-Methoxyflavone-induced AMPKα activation inhibits NF-κB and P38 MAPK signaling to attenuate influenza A virus-mediated inflammation and lung injury in vitro and in vivo

Sushan Yang, Linxin Wang, Xiping Pan, Yueyun Liang, Yuehan Zhang, Jing Li & Beixian Zhou
Additional file 1. Original images for western blot.

Additional file 1 of Construction of a ferroptosis-related five-lncRNA signature for predicting prognosis and immune response in thyroid carcinoma

Yuan Qin, Dai Zhang, Huan Zhang, Lan Hou, Zhe Wang, Liu Yang, Mingkun Zhang, Ge Zhao, Qing Yao, Rui Ling & Juliang Zhang
Additional file 1: Table S1. Ferroptosis-related genes.

Additional file 3 of Construction of a ferroptosis-related five-lncRNA signature for predicting prognosis and immune response in thyroid carcinoma

Yuan Qin, Dai Zhang, Huan Zhang, Lan Hou, Zhe Wang, Liu Yang, Mingkun Zhang, Ge Zhao, Qing Yao, Rui Ling & Juliang Zhang
Additional file 3: Table S3. Primer sequences used for qRT-PCR.

Additional file 3 of Construction of a ferroptosis-related five-lncRNA signature for predicting prognosis and immune response in thyroid carcinoma

Yuan Qin, Dai Zhang, Huan Zhang, Lan Hou, Zhe Wang, Liu Yang, Mingkun Zhang, Ge Zhao, Qing Yao, Rui Ling & Juliang Zhang
Additional file 3: Table S3. Primer sequences used for qRT-PCR.

Construction of a ferroptosis-related five-lncRNA signature for predicting prognosis and immune response in thyroid carcinoma

Yuan Qin, Dai Zhang, Huan Zhang, Lan Hou, Zhe Wang, Liu Yang, Mingkun Zhang, Ge Zhao, Qing Yao, Rui Ling & Juliang Zhang
Abstract Background Thyroid carcinoma (THCA) is the most common endocrine-related malignant tumor. Despite the good prognosis, some THCA patients may deteriorate into more aggressive diseases, leading to poor survival. This may be alleviated by developing a novel model to predict the risk of THCA, including recurrence and survival. Ferroptosis is an iron-dependent, oxidative, non-apoptotic form of cell death initially described in mammalian cells, and plays an important role in various cancers. To explore the potential...

Additional file 1 of ETV2 promotes osteogenic differentiation of human dental pulp stem cells through the ERK/MAPK and PI3K-Akt signaling pathways

Jing Li, Haoran Du, Xin Ji, Yihan Chen, Yishuai Li, Boon Chin Heng & Jianguang Xu
Additional file 1: Figure S1. The mRNA level of CBFA1 in qRT-PCR (a) and RNA-Seq (b). *P < 0.05.

Additional file 4 of ETV2 promotes osteogenic differentiation of human dental pulp stem cells through the ERK/MAPK and PI3K-Akt signaling pathways

Jing Li, Haoran Du, Xin Ji, Yihan Chen, Yishuai Li, Boon Chin Heng & Jianguang Xu
Additional file 4: Figure S4. HE (scale bar = 50 μm) and Masson (scale bar = 50 μm) staining were performed to evaluate ectopic bone formation in nude mice (n=4).

Interactions of CDKAL1 rs7747752 polymorphism and serum levels of L-carnitine and choline are related to increased risk of gestational diabetes mellitus

Hui Wang, Jing Li, Jinnan Liu, Junhong Leng, Weiqin Li, Zhijie Yu, Claudia H. T. Tam, Gang Hu, Ronald C. W. Ma, Zhongze Fang, Ying Wang & Xilin Yang
Abstract Background Interactions between genetic, metabolic, and environmental factors lead to gestational diabetes mellitus (GDM). We aimed to examine interactive effects of cyclin-dependent kinase 5 regulatory subunit-associated protein1-like 1(CDKAL1) rs7747752 polymorphism with low serum levels of L-carnitine, choline, and betaine for GDM. Methods A nested case-control study of 207 GDM women and their one-to-one, age-matched controls was organized from a prospective cohort of pregnant women in Tianjin, China. Conditional logistic regressions were used to test...

Additional file 7 of Aberrant methylation of Serpine1 mediates lung injury in neonatal mice prenatally exposed to intrauterine inflammation

Dongting Yao, Jiuru Zhao, Qianqian Zhang, Tao Wang, Meng Ni, Sudong Qi, Qianwen Shen, Wei Li, Baihe Li, Xiya Ding & Zhiwei Liu
Additional file 7: Figure S7. Schematic representation of the molecular mechanisms underlying IUI-induced lung injury in neonatal mice.

Association between healthy lifestyle and the occurrence of cardiometabolic multimorbidity in hypertensive patients: a prospective cohort study of UK Biobank

Hejian Xie, Jinchen Li, Xuanmeng Zhu, Jing Li, Jinghua Yin, Tianqi Ma, Yi Luo, Lingfang He, Yongping Bai, Guogang Zhang, Xunjie Cheng & Chuanchang Li
Abstract Background Cardiometabolic multimorbidity (CMM) is becoming increasingly common in patients with hypertension, and it is well established that healthy lifestyle plays a key role in the prevention of hypertension. However, the association between combined lifestyle factors and CMM in patients with hypertension is uncertain. Methods This prospective analysis included the data (obtained from the UK biobank) of participants with hypertension who did not have coronary heart disease (CHD), stroke, or diabetes. The outcome was...

Additional file 1 of Association between healthy lifestyle and the occurrence of cardiometabolic multimorbidity in hypertensive patients: a prospective cohort study of UK Biobank

Hejian Xie, Jinchen Li, Xuanmeng Zhu, Jing Li, Jinghua Yin, Tianqi Ma, Yi Luo, Lingfang He, Yongping Bai, Guogang Zhang, Xunjie Cheng & Chuanchang Li
Additional file 1: Figure S1. The relationship between a healthy lifestyle and CMM in subgroup analyses. Figure S2. The relationship between a healthy lifestyle and CMM in seven sensitivity analyses. Figure S3. The frequency distribution graph of the weighted healthy lifestyle score for the whole population. Figure S4. The frequency distribution graph of the weighted healthy lifestyle score for 2/3 of the population. Figure S5. The frequency distribution graph of the sum healthy lifestyle score...

Association between healthy lifestyle and the occurrence of cardiometabolic multimorbidity in hypertensive patients: a prospective cohort study of UK Biobank

Hejian Xie, Jinchen Li, Xuanmeng Zhu, Jing Li, Jinghua Yin, Tianqi Ma, Yi Luo, Lingfang He, Yongping Bai, Guogang Zhang, Xunjie Cheng & Chuanchang Li
Abstract Background Cardiometabolic multimorbidity (CMM) is becoming increasingly common in patients with hypertension, and it is well established that healthy lifestyle plays a key role in the prevention of hypertension. However, the association between combined lifestyle factors and CMM in patients with hypertension is uncertain. Methods This prospective analysis included the data (obtained from the UK biobank) of participants with hypertension who did not have coronary heart disease (CHD), stroke, or diabetes. The outcome was...

Additional file 1 of A CT-based nomogram for differentiating invasive fungal disease of the lung from bacterial pneumonia

Meilin Gong, Jingmei Xu, Kang Li, Ke Li, Yuwei Xia, Yang Jing, Jiafei Chen, Jing Li, Jing Yang, Mingshan Du, Wenjing Hou, Yuan Ou, Lian Li & Wei Chen
Additional file 1. On the orininal data of the study.

Relationship between body composition and bone mineral density in postmenopausal women with type 2 diabetes mellitus

Lei Gao, Ping Zhang, Yan Wang, Wei Zhang, Jian Zhao, Ying Liu, Jing Liu & Shaoqiang He
Abstract Background The aim of the study were to analyze the lumbar volumetric bone mineral density (BMD), fat distribution and changes of skeletal muscle with quantitative computed tomography (QCT) in postmenopausal women with type 2 diabetes mellitus (T2DM), and to evaluate the relationship between body composition and BMD. Methods One hundred seventy-seven postmenopausal women with T2DM and 136 postmenopausal women without diabetes were included in the study and were divided into two groups according to...

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