68 Works

Additional file 2 of Meal replacement as a weight loss strategy for night shift workers with obesity: a protocol for a randomized controlled trial

Piumika Sooriyaarachchi, Ranil Jayawardena, Toby Pavey & Neil A. King
Additional file 2. Nutritional composition of the meal replacement product.

Additional file 2 of CELPI: trial protocol for a randomised controlled trial of a Carer End of Life Planning Intervention in people dying with dementia

G Arendts, L Chenoweth, BJ Hayes, E Campbell, M Agar, C Etherton-Beer, K Spilsbury, K Howard, G Braitberg, M Cubitt, C Sheehan, L Magann, T Sudharshan, LM Schnitker, J Pearce, I Gilmore, N Cerra, J duPreez, R Jaworski, S-C Soh & A Celenza
Additional file 2. Fidelity Checklist.

CELPI: trial protocol for a randomised controlled trial of a Carer End of Life Planning Intervention in people dying with dementia

G Arendts, L Chenoweth, BJ Hayes, E Campbell, M Agar, C Etherton-Beer, K Spilsbury, K Howard, G Braitberg, M Cubitt, C Sheehan, L Magann, T Sudharshan, LM Schnitker, J Pearce, I Gilmore, N Cerra, J duPreez, R Jaworski, S-C Soh & A Celenza
Abstract Background Dementia is a leading cause of death in developed nations. Despite an often distressing and symptom laden end of life, there are systematic barriers to accessing palliative care in older people dying of dementia. Evidence exists that 70% of people living with severe dementia attend an emergency department (ED) in their last year of life. The aim of this trial is to test whether a Carer End of Life Planning Intervention (CELPI), co-designed...

Intersection of food insecurity and moral experiences of those involved in paediatric healthcare: A scoping review of child, caregiver and healthcare provider perspectives

Amanda J Taylor, Sabine Baker & Danielle Gallegos
Food insecurity is a significant social and health issue for children in high-income countries and contributes to sub-optimal child outcomes. This scoping review examines how food insecurity intersects with the moral experiences of those involved in providing and receiving paediatric health care. Multiple databases were searched using a priori inclusion criteria, papers were screened by multiple reviewers. Searches yielded nine papers. Descriptive data was summarised and qualitative results extracted from included papers were analysed using...

Additional file 3 of Impact of a prospective feedback loop on care review activities in older patients at the end of life. A stepped-wedge randomised trial

Christine Brown, Xing J. Lee, Alison Farrington, Carla Shield, Hannah E. Carter, Steven M. McPhail, Magnolia Cardona, Kenneth Hillman, Leonie Callaway, Lindy Willmott, Ben P. White, Gillian Harvey, Nicholas Graves & Adrian G. Barnett
Additional file 3. Supplementary Figures and tables.

Simulated cannabis days-of-use data

Mark Chambers & Christopher Drovandi
Background: The numbers of days that people consume alcohol and other drugs over a fixed time interval, such as 28 days, are often collected in surveys for research in the addictions field. The presence of an upper bound on these variables can result in response distributions with "ceiling effects". Also, if some peoples’ substance use behaviors are characterized by various weekly patterns of use, summaries of substance days-of-use over longer periods can exhibit multiple modes....

Additional file 1 of Stress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients

John P. R. Moore, Yahya Shehabi, Michael C. Reade, Michael Bailey, John F. Fraser, Lauren Murray, Christopher Anstey & Mervyn Singer
Additional file 1. Appendix 1. Supplementary figures and tables.

Adherence to 24-hour movement guidelines among rural Brazalian preschool children: associations with parenting practices

Widjane Sheila Ferreira Goncalves, Rebecca Byrne, Pedro Israel Cabral de Lira, Marcelo Tavares Viana & Stewart G. Trost
Abstract Background: Young children residing in rural areas of low-and-middle income countries (LMICs) such as Brazil are at greater risk of obesity and related chronic health conditions. Yet, the extent to which rural preschool children from Brazil aged 3- to 6-years meet the World Health Organisation (WHO) 24-hour movement guidelines is unknown. Parents play a central role in the development of children’s movement behaviors with logistic support, co-participation, modelling, and setting rules and limits recognized...

Additional file 1 of Understanding how and under what circumstances decision coaching works for people making healthcare decisions: a realist review

Junqiang Zhao, Janet Jull, Jeanette Finderup, Maureen Smith, Simone Maria Kienlin, Anne Christin Rahn, Sandra Dunn, Yumi Aoki, Leanne Brown, Gillian Harvey & Dawn Stacey
Additional file 1: Appendix A: Demographic of executive and stakeholder group members. Appendix B: Initial program theory. Appendix C: Relevance rating checklist. Appendix D: Data extraction form.

Meal replacement as a weight loss strategy for night shift workers with obesity: a protocol for a randomized controlled trial

Piumika Sooriyaarachchi, Ranil Jayawardena, Toby Pavey & Neil A. King
Abstract Background Shift work is considered a risk factor for a number of chronic health conditions including obesity. Weight reduction in obese patients lowers the risk for cardiovascular disease, diabetes, certain cancers, and mortality. Achieving a negative energy balance by providing low-calorie meal replacements is widely used for weight management. This study aims to evaluate the impact of a low-calorie “meal-replacement” on the weight and metabolic parameters of shift workers with obesity. Methods This trial...

Different epidemiology of bloodstream infections in COVID-19 compared to non-COVID-19 critically ill patients: a descriptive analysis of the Eurobact II study

Niccolò Buetti, Alexis Tabah, Ambre Loiodice, Stéphane Ruckly, Abdullah Tarik Aslan, Giorgia Montrucchio, Andrea Cortegiani, Nese Saltoglu, Bircan Kayaaslan, Firdevs Aksoy, Akova Murat, Özlem Akdoğan, Kemal Tolga Saracoglu, Cem Erdogan, Marc Leone, Ricard Ferrer, José-Artur Paiva, Yoshiro Hayashi, Mahesh Ramanan, Andrew Conway Morris, François Barbier & Jean-François Timsit
Abstract Background The study aimed to describe the epidemiology and outcomes of hospital-acquired bloodstream infections (HABSIs) between COVID-19 and non-COVID-19 critically ill patients. Methods We used data from the Eurobact II study, a prospective observational multicontinental cohort study on HABSI treated in ICU. For the current analysis, we selected centers that included both COVID-19 and non-COVID-19 critically ill patients. We performed descriptive statistics between COVID-19 and non-COVID-19 in terms of patients’ characteristics, source of infection...

Integrated co-design: A model for co-designing with multiple stakeholder groups from the ‘fuzzy’ front-end to beyond project delivery

Jeremy Kerr, Michael Whelan, Okansa Zelenko, Keely Harper-Hill & Clare Villalba

Phylogenetic analysis of policistronic amino-acid sequences encoded by 116 flavivirus genomes

Lars Jermiin, Vivek Jayaswal & John Robinson
Recently, Genome Biology and Evolution (11:3341-3352) published three statistical tests for testing whether alignments of sequence data violate the phylogenetic assumption of evolution under homogeneous conditions. The tests extend the matched-pairs tests of symmetry, marginal symmetry, and internal symmetry for pairs of aligned homologous sequences to the case where a whole alignment is considered. Here we reveal that the new tests are misleading. We explain why this is so, reveal how the tests of whole...

Cytotoxic flavonoids from the leaves of Callicarpa nudiflora hook

Jin-Lin Zhang, Yin Xiao, Lu Zhou, Shao-Yang Yin, Jia-Yin Long, Hong-Lin Xiang, Xi-Feng Sheng & Hui Zou
A new flavonoid glycoside, luteolin-3′-O-β-D-6″-acetyl glucopyranoside (1), along with six known flavonoids, were isolated from the leaves of Callicarpa nudiflora Hook. The structures of the isolated compounds were established on the basis of extensive spectroscopic analyses. Compound 6 exhibited potent cytotoxicity and compounds 1 and 7 exhibited moderate cytotoxicity against human hepatocellular carcinoma SMMC-7721 cells.

Additional file 3 of Impact of a prospective feedback loop on care review activities in older patients at the end of life. A stepped-wedge randomised trial

Christine Brown, Xing J. Lee, Alison Farrington, Carla Shield, Hannah E. Carter, Steven M. McPhail, Magnolia Cardona, Kenneth Hillman, Leonie Callaway, Lindy Willmott, Ben P. White, Gillian Harvey, Nicholas Graves & Adrian G. Barnett
Additional file 3. Supplementary Figures and tables.

Impact of a prospective feedback loop on care review activities in older patients at the end of life. A stepped-wedge randomised trial

Christine Brown, Xing J. Lee, Alison Farrington, Carla Shield, Hannah E. Carter, Steven M. McPhail, Magnolia Cardona, Kenneth Hillman, Leonie Callaway, Lindy Willmott, Ben P. White, Gillian Harvey, Nicholas Graves & Adrian G. Barnett
Abstract Background Hospitalisation rates for older people are increasing, with end-of-life care becoming a more medicalised experience. Innovative approaches are warranted to support early identification of the end-of-life phase, communicate prognosis, provide care consistent with people’s preferences, and improve the use of healthcare resources. The Intervention for Appropriate Care and Treatment (InterACT) trial aimed to increase appropriate care and treatment decisions for older people at the end of life, through implementation of a prospective feedback...

CELPI: trial protocol for a randomised controlled trial of a Carer End of Life Planning Intervention in people dying with dementia

G Arendts, L Chenoweth, BJ Hayes, E Campbell, M Agar, C Etherton-Beer, K Spilsbury, K Howard, G Braitberg, M Cubitt, C Sheehan, L Magann, T Sudharshan, LM Schnitker, J Pearce, I Gilmore, N Cerra, J duPreez, R Jaworski, S-C Soh & A Celenza
Abstract Background Dementia is a leading cause of death in developed nations. Despite an often distressing and symptom laden end of life, there are systematic barriers to accessing palliative care in older people dying of dementia. Evidence exists that 70% of people living with severe dementia attend an emergency department (ED) in their last year of life. The aim of this trial is to test whether a Carer End of Life Planning Intervention (CELPI), co-designed...

Additional file 1 of Health service use for young males and females with a mental disorder is higher than their peers in a population-level matched cohort

Rebecca J Mitchell, Anne McMaugh, Reidar P Lystad, Cate M Cameron & Olav Nielssen
Additional file 1: Supplementary Table 1. Case identification and diagnostic classification. Supplementary Table 2. Health conditions and ICD-10-AM classifications. Supplementary Table 3. Principal diagnosis of the first read mission for young people hospitalised with a mental disorder by sex, linked health and mortality data NSW, 2005-2018. Supplementary Table 4. Rate ratio of further hospital admissions for young people hospitalised with a mental disorder and their matched comparison by sex, linked health and mortality data NSW,...

Stress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients

John P. R. Moore, Yahya Shehabi, Michael C. Reade, Michael Bailey, John F. Fraser, Lauren Murray, Christopher Anstey & Mervyn Singer
Abstract Background Sedative agents may variably impact the stress response. Dexmedetomidine is a sympatholytic alpha2-adrenergic agonist mainly used as a second-line sedative agent in mechanically ventilated patients. We hypothesised that early sedation with dexmedetomidine as the primary agent would result in a reduced stress response compared to usual sedatives in critically ill ventilated adults. Methods This was a prospective sub-study nested within a multi-centre randomised controlled trial of early sedation with dexmedetomidine versus usual care....

Natural variation at a single gene generates sexual antagonism across fitness components in Drosophila

Bosco Rusuwa, Henry Chung, Scott Allen, Francesca Frentui & Steve Chenoweth
Mutations with conflicting fitness effects in males and females accumulate in sexual populations, reducing their adaptive capacity. Although quantitative genetic studies indicate that sexually antagonistic polymorphisms are common, their molecular basis and population genetic properties remain poorly understood. Here, we show in fruit flies how natural variation at a single gene generates sexual antagonism through phenotypic effects on cuticular hydrocarbon (CHC) traits that function as both mate signals and protectors against abiotic stress across a...

Morphological characteristics of pollen from triploid watermelon and its fate on stigmas in a hybrid crop production system

Erandi C. W. Subasinghe Arachchige, Lisa J. Evans, Ulrika Samnegard & Romina Rader
Hybrid crop production is more reliant on pollinators compared to open-pollinated crops because they require cross-pollination between a male-fertile and a male-sterile line. Little is known about how stigma receipt of pollen from male-sterile genotypes affects reproduction in hybrids. Non-viable and non-compatible pollen cannot fertilise plant ovules, but may still interfere with pollination success. Here we used seedless watermelon (Citrullus lanatus (Thunb.) Matsum. & Nakai) as a model hybrid plant, to evaluate the morphology, physiology,...

Additional file 1 of Meal replacement as a weight loss strategy for night shift workers with obesity: a protocol for a randomized controlled trial

Piumika Sooriyaarachchi, Ranil Jayawardena, Toby Pavey & Neil A. King
Additional file 1. SPIRIT checklist.

Additional file 1 of Meal replacement as a weight loss strategy for night shift workers with obesity: a protocol for a randomized controlled trial

Piumika Sooriyaarachchi, Ranil Jayawardena, Toby Pavey & Neil A. King
Additional file 1. SPIRIT checklist.

Additional file 4 of Meal replacement as a weight loss strategy for night shift workers with obesity: a protocol for a randomized controlled trial

Piumika Sooriyaarachchi, Ranil Jayawardena, Toby Pavey & Neil A. King
Additional file 4. Consent form.

Understanding how and under what circumstances decision coaching works for people making healthcare decisions: a realist review

Junqiang Zhao, Janet Jull, Jeanette Finderup, Maureen Smith, Simone Maria Kienlin, Anne Christin Rahn, Sandra Dunn, Yumi Aoki, Leanne Brown, Gillian Harvey & Dawn Stacey
Abstract Background Decision coaching is non-directive support delivered by a trained healthcare provider to help people prepare to actively participate in making healthcare decisions. This study aimed to understand how and under what circumstances decision coaching works for people making healthcare decisions. Methods We followed the realist review methodology for this study. This study was built on a Cochrane systematic review of the effectiveness of decision coaching interventions for people facing healthcare decisions. It involved...

Registration Year

  • 2022
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Affiliations

  • Queensland University of Technology
    68
  • University of Queensland
    22
  • UNSW Sydney
    19
  • Flinders University
    11
  • Royal Brisbane and Women's Hospital
    11
  • Bond University
    8
  • Prince Charles Hospital
    8
  • University of Malta
    8
  • Ministry for Health
    8
  • Metro South Health
    7