10 Works

Additional file 1 of Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle

Anne Vaiman, Sébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte & Amandine Duchesne
Additional file 1: Table S1. List of the disorders in animals (except man, mouse, rat and zebrafish) which include “cleft palate” as a clinical sign. All the data originate from OMIA (Online Mendelian Inheritance in Animals, www.omia.org ). All the cattle disorders are written in bold. AR: autosomal recessive; AD: autosomal dominant; UK: unknown.

Additional file 3 of Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle

Anne Vaiman, Sébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte & Amandine Duchesne
Additional file 3: Figure S1. Results of the homozygosity mapping on all the bovine chromosomes. LRT: likelihood-ratio test; BTA: Bos taurus chromosome.

Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle

Anne Vaiman, Sébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte & Amandine Duchesne
Abstract Background The palate is a structure separating the oral and nasal cavities and its integrity is essential for feeding and breathing. The total or partial opening of the palate is called a cleft palate and is a common malformation in mammals with environmental or hereditary aetiologies. Generally, it compromises life expectancy in the absence of surgical repair. A new form of non-syndromic cleft palate arose recently in Limousine cattle, with animals referred to the...

Additional file 1 of Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle

Anne Vaiman, Sébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte & Amandine Duchesne
Additional file 1: Table S1. List of the disorders in animals (except man, mouse, rat and zebrafish) which include “cleft palate” as a clinical sign. All the data originate from OMIA (Online Mendelian Inheritance in Animals, www.omia.org ). All the cattle disorders are written in bold. AR: autosomal recessive; AD: autosomal dominant; UK: unknown.

Additional file 3 of Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle

Anne Vaiman, Sébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte & Amandine Duchesne
Additional file 3: Figure S1. Results of the homozygosity mapping on all the bovine chromosomes. LRT: likelihood-ratio test; BTA: Bos taurus chromosome.

Additional file 4 of Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle

Anne Vaiman, Sébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte & Amandine Duchesne
Additional file 4: Table S3. Frequency analysis of the MYH3 mutations in 834,792 animals from 14 commercial breeds based on genotyping with EuroG10k v8 and EuroGMD SNP chips. The two mutations are totally linked, thus the frequency is the same for both mutations. freq_WTall: frequency of the WT allele; freq_MUTall: frequency of the mutated allele.

Additional file 4 of Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle

Anne Vaiman, Sébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte & Amandine Duchesne
Additional file 4: Table S3. Frequency analysis of the MYH3 mutations in 834,792 animals from 14 commercial breeds based on genotyping with EuroG10k v8 and EuroGMD SNP chips. The two mutations are totally linked, thus the frequency is the same for both mutations. freq_WTall: frequency of the WT allele; freq_MUTall: frequency of the mutated allele.

Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle

Anne Vaiman, Sébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte & Amandine Duchesne
Abstract Background The palate is a structure separating the oral and nasal cavities and its integrity is essential for feeding and breathing. The total or partial opening of the palate is called a cleft palate and is a common malformation in mammals with environmental or hereditary aetiologies. Generally, it compromises life expectancy in the absence of surgical repair. A new form of non-syndromic cleft palate arose recently in Limousine cattle, with animals referred to the...

Additional file 2 of Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle

Anne Vaiman, Sébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte & Amandine Duchesne
Additional file 2: Table S2. Characteristics of the 26 Limousine CP-affected animals described in this study.

Additional file 2 of Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle

Anne Vaiman, Sébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte & Amandine Duchesne
Additional file 2: Table S2. Characteristics of the 26 Limousine CP-affected animals described in this study.

Registration Year

  • 2022
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Resource Types

  • Dataset
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  • Audiovisual
    2
  • Collection
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Affiliations

  • Animal Genetics and Integrative Biology Unit
    10
  • University of Paris-Saclay
    10
  • Oniris
    10