16 Works

Additional file 1 of Comparative evaluation of propolis nanostructured lipid carriers and its crude extract for antioxidants, antimicrobial activity, and skin regeneration potential

Ola M. Elkhateeb, Mohamed E. I. Badawy, Ahmed E. Noreldin, Howaida M. Abou-Ahmed, Mahmoud H. El-Kammar & Hoda A. Elkhenany
Additional file 1: Histopathological examination of skin treated with propolis-EXTR and propolis-NLCs after 7 and 21 days.

Additional file 1 of Comparative evaluation of propolis nanostructured lipid carriers and its crude extract for antioxidants, antimicrobial activity, and skin regeneration potential

Ola M. Elkhateeb, Mohamed E. I. Badawy, Ahmed E. Noreldin, Howaida M. Abou-Ahmed, Mahmoud H. El-Kammar & Hoda A. Elkhenany
Additional file 1: Histopathological examination of skin treated with propolis-EXTR and propolis-NLCs after 7 and 21 days.

Comparative evaluation of propolis nanostructured lipid carriers and its crude extract for antioxidants, antimicrobial activity, and skin regeneration potential

Ola M. Elkhateeb, Mohamed E. I. Badawy, Ahmed E. Noreldin, Howaida M. Abou-Ahmed, Mahmoud H. El-Kammar & Hoda A. Elkhenany
Abstract Background Propolis extracted from beehives has been conferred with natural antimicrobial and antioxidant properties. Hence, it has been recommended as a wound healing therapy. This study investigated the additive value of nanotechnology to the herbal extract, (propolis rebuts), after which we examined its efficacy in wound healing. Methods Propolis nanostructured lipid carriers (NLCs) were first prepared using the emulsion-evaporation-solidification method at three concentrations. Then, we compared their flavonoid and phenolic contents and phenolic contents....

Spectroscopic details on the molecular structure of pyrimidine‑2‑thiones heterocyclic compounds: computational and antiviral activity against the main protease enzyme of SARS-CoV-2

Doaa S. El Sayed & El-Sayed M. Abdelrehim
Abstract Computational tools in investigating of spectral heterocyclic compounds ranges based on pyrimidine‑2‑thiones, take some importance in identifying their molecular and electronic behavior. Some charcoal heterocyclic compounds were previously synthesized in our laboratory and their experimental results were compared with the computational evaluation. Computational spectroscopic analytical items (IR, NMR and UV–Vis) were calculated using the more popular DFT methods and the predicted results were compared with the reported experimental ones. Quantum and chemical parameters were...

Additional file 1 of Spectroscopic details on the molecular structure of pyrimidine‑2‑thiones heterocyclic compounds: computational and antiviral activity against the main protease enzyme of SARS-CoV-2

Doaa S. El Sayed & El-Sayed M. Abdelrehim
Additional file 1: Table S1. The optimum Geometrical parameters (bond lengths and bond angles) of the studied heterocyclic compounds. Table S2. Molecular reactivity parameters using TD-DFT-B3LYP/ 6-31G (d,p) of the studied heterocyclic compounds in solution. Table S3. Values of 1H, 13C NMR chemical shifts (ppm) of the studied by using heterocyclic compounds by using different ab initio functionals, and experimental data. Table S4. Values of the mulliken charges, Fukui function of L1. Table S5. Values...

Association between biochemical parameters and ultrasonographic measurement for the assessment of hepatic lipidosis in dairy cows

Besheer G. Elshafey, Ahmed Elfadadny, Samy Metwally, Asmaa G. Saleh, Rokaia F. Ragab, Rania Hamada, Ahmed S. Mandour, Amin Omar Hendawy, Luay Alkazmi, Hanan A. Ogaly & Gaber El-Saber Batiha
Hepatic lipidosis (HL) is a serious metabolic disorder that affects transient high-producing dairy cows. However, there are many laboratory methods could help in the assessment of HL in dairy cows, the definite diagnosis of the disease under field conditions remains a challenge because of the non-specificity of clinical parameters. The aim of the study was to investigate the utility of serum biomarkers, and ultrasonography (US) measurement to diagnose HL in dairy cows. Forty Holstein dairy...

Additional file 1 of Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa-Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Inemesit A. Udofia, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani & Gaber El-Saber Batiha
Additional file 1. HPLC chromatogram of ethanolic leaf extract of cannabis.

Additional file 1 of Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa-Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Inemesit A. Udofia, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani & Gaber El-Saber Batiha
Additional file 1. HPLC chromatogram of ethanolic leaf extract of cannabis.

Spectroscopic details on the molecular structure of pyrimidine‑2‑thiones heterocyclic compounds: computational and antiviral activity against the main protease enzyme of SARS-CoV-2

Doaa S. El Sayed & El-Sayed M. Abdelrehim
Abstract Computational tools in investigating of spectral heterocyclic compounds ranges based on pyrimidine‑2‑thiones, take some importance in identifying their molecular and electronic behavior. Some charcoal heterocyclic compounds were previously synthesized in our laboratory and their experimental results were compared with the computational evaluation. Computational spectroscopic analytical items (IR, NMR and UV–Vis) were calculated using the more popular DFT methods and the predicted results were compared with the reported experimental ones. Quantum and chemical parameters were...

Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa-Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Udofia A. Inemesit, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani & Gaber El-Saber Batiha
Abstract Background Data available support that ninety percent of male infertility cases are due to low sperm counts. There is a scarcity of data on the medicinal effects of cannabis on fertility. This study evaluated testicular function and sperm quality modulation with cannabis in rats. Methodology Twenty-five male Wistar rats were randomly grouped into five: A, B, C, and D, each group have 5 rats. A (control): 0.2 ml 2% DMSO, B (vitamin C): 90...

Additional file 1 of Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa-Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Udofia A. Inemesit, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani & Gaber El-Saber Batiha
Additional file 1. HPLC chromatogram of ethanolic leaf extract of cannabis.

Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa-Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Inemesit A. Udofia, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani & Gaber El-Saber Batiha
Abstract Background Data available support that ninety percent of male infertility cases are due to low sperm counts. There is a scarcity of data on the medicinal effects of cannabis on fertility. This study evaluated testicular function and sperm quality modulation with cannabis in rats. Methodology Twenty-five male Wistar rats were randomly grouped into five: A, B, C, and D, each group have 5 rats. A (control): 0.2 ml 2% DMSO, B (vitamin C): 90...

Comparative evaluation of propolis nanostructured lipid carriers and its crude extract for antioxidants, antimicrobial activity, and skin regeneration potential

Ola M. Elkhateeb, Mohamed E. I. Badawy, Ahmed E. Noreldin, Howaida M. Abou-Ahmed, Mahmoud H. El-Kammar & Hoda A. Elkhenany
Abstract Background Propolis extracted from beehives has been conferred with natural antimicrobial and antioxidant properties. Hence, it has been recommended as a wound healing therapy. This study investigated the additive value of nanotechnology to the herbal extract, (propolis rebuts), after which we examined its efficacy in wound healing. Methods Propolis nanostructured lipid carriers (NLCs) were first prepared using the emulsion-evaporation-solidification method at three concentrations. Then, we compared their flavonoid and phenolic contents and phenolic contents....

Additional file 1 of Spectroscopic details on the molecular structure of pyrimidine‑2‑thiones heterocyclic compounds: computational and antiviral activity against the main protease enzyme of SARS-CoV-2

Doaa S. El Sayed & El-Sayed M. Abdelrehim
Additional file 1: Table S1. The optimum Geometrical parameters (bond lengths and bond angles) of the studied heterocyclic compounds. Table S2. Molecular reactivity parameters using TD-DFT-B3LYP/ 6-31G (d,p) of the studied heterocyclic compounds in solution. Table S3. Values of 1H, 13C NMR chemical shifts (ppm) of the studied by using heterocyclic compounds by using different ab initio functionals, and experimental data. Table S4. Values of the mulliken charges, Fukui function of L1. Table S5. Values...

Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa-Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Inemesit A. Udofia, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani & Gaber El-Saber Batiha
Abstract Background Data available support that ninety percent of male infertility cases are due to low sperm counts. There is a scarcity of data on the medicinal effects of cannabis on fertility. This study evaluated testicular function and sperm quality modulation with cannabis in rats. Methodology Twenty-five male Wistar rats were randomly grouped into five: A, B, C, and D, each group have 5 rats. A (control): 0.2 ml 2% DMSO, B (vitamin C): 90...

Association between biochemical parameters and ultrasonographic measurement for the assessment of hepatic lipidosis in dairy cows

Besheer G. Elshafey, Ahmed Elfadadny, Samy Metwally, Asmaa G. Saleh, Rokaia F. Ragab, Rania Hamada, Ahmed S. Mandour, Amin Omar Hendawy, Luay Alkazmi, Hanan A. Ogaly & Gaber El-Saber Batiha
Hepatic lipidosis (HL) is a serious metabolic disorder that affects transient high-producing dairy cows. However, there are many laboratory methods could help in the assessment of HL in dairy cows, the definite diagnosis of the disease under field conditions remains a challenge because of the non-specificity of clinical parameters. The aim of the study was to investigate the utility of serum biomarkers, and ultrasonography (US) measurement to diagnose HL in dairy cows. Forty Holstein dairy...

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