426 Works

Additional file 4 of Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle: a systematic review and meta-analysis of individual patient data

Sean M. Hughes, Claire N. Levy, Ronit Katz, Erica M. Lokken, Melis N. Anahtar, Melissa Barousse Hall, Frideborg Bradley, Philip E. Castle, Valerie Cortez, Gustavo F. Doncel, Raina Fichorova, Paul L. Fidel, Keith R. Fowke, Suzanna C. Francis, Mimi Ghosh, Loris Y. Hwang, Mariel Jais, Vicky Jespers, Vineet Joag, Rupert Kaul, Jordan Kyongo, Timothy Lahey, Huiying Li, Julia Makinde, Lyle R. McKinnon … & Florian Hladik
Additional file 4. Concentration and forest plots for each individual immune mediator. Concentration plots - Each symbol shows the concentration of the indicated immune mediator in a single sample. Each study is plotted separately. Lines connect samples from the same participant; in some cases participants provided multiple samples in the same phase, in which case multiple symbols within the same phase may be connected. Pale grey symbols are below the lower limit of detection and...

Additional file 1 of Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle: a systematic review and meta-analysis of individual patient data

Sean M. Hughes, Claire N. Levy, Ronit Katz, Erica M. Lokken, Melis N. Anahtar, Melissa Barousse Hall, Frideborg Bradley, Philip E. Castle, Valerie Cortez, Gustavo F. Doncel, Raina Fichorova, Paul L. Fidel, Keith R. Fowke, Suzanna C. Francis, Mimi Ghosh, Loris Y. Hwang, Mariel Jais, Vicky Jespers, Vineet Joag, Rupert Kaul, Jordan Kyongo, Timothy Lahey, Huiying Li, Julia Makinde, Lyle R. McKinnon … & Florian Hladik
Additional file 1. Supporting methods documents. PRISMA-P and PRISMA-IPD checklists, database search strategies, manuscript screening form, risk of bias instrument, and strength of evidence tool.

Additional file 3 of Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle: a systematic review and meta-analysis of individual patient data

Sean M. Hughes, Claire N. Levy, Ronit Katz, Erica M. Lokken, Melis N. Anahtar, Melissa Barousse Hall, Frideborg Bradley, Philip E. Castle, Valerie Cortez, Gustavo F. Doncel, Raina Fichorova, Paul L. Fidel, Keith R. Fowke, Suzanna C. Francis, Mimi Ghosh, Loris Y. Hwang, Mariel Jais, Vicky Jespers, Vineet Joag, Rupert Kaul, Jordan Kyongo, Timothy Lahey, Huiying Li, Julia Makinde, Lyle R. McKinnon … & Florian Hladik
Additional file 3. Code and data. IPD from co-authors who agreed to share it, results of all analyses presented in the paper, and R code files necessary to reproduce the analysis and figures.

Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle: a systematic review and meta-analysis of individual patient data

Sean M. Hughes, Claire N. Levy, Ronit Katz, Erica M. Lokken, Melis N. Anahtar, Melissa Barousse Hall, Frideborg Bradley, Philip E. Castle, Valerie Cortez, Gustavo F. Doncel, Raina Fichorova, Paul L. Fidel, Keith R. Fowke, Suzanna C. Francis, Mimi Ghosh, Loris Y. Hwang, Mariel Jais, Vicky Jespers, Vineet Joag, Rupert Kaul, Jordan Kyongo, Timothy Lahey, Huiying Li, Julia Makinde, Lyle R. McKinnon … & Florian Hladik
Abstract Background Hormonal changes during the menstrual cycle play a key role in shaping immunity in the cervicovaginal tract. Cervicovaginal fluid contains cytokines, chemokines, immunoglobulins, and other immune mediators. Many studies have shown that the concentrations of these immune mediators change throughout the menstrual cycle, but the studies have often shown inconsistent results. Our understanding of immunological correlates of the menstrual cycle remains limited and could be improved by meta-analysis of the available evidence. Methods...

Systemic Bias and DEIA Reform of the Force Concept Inventory

Dana Milstein & Jade Winn

Toddlers' Selection of Mature Helpers in the Context of Problem Solving

Alexandra Little
It has been established that young children seek help from others when engaged in a task that exceeds their competence (Vredenburgh & Kushnir, 2015). By age 2, children attend to a potential helper’s competence when deciding to seek help (Cluver et al., 2013). However, not much is known otherwise about the basis on which children decide whom to address for help. This study investigates whether children choose helpers based on maturity (infant versus adult; small...

Harmonized Mex-Cog, Version A

Sandy Chien, Codi Young, Erik Meijer, Kanghong Shao, Alden Gross, Alejandra Michaels-Obregon, Rebeca Wong & Jinkook Lee

Anticeramide Improves Sjögren’s Syndrome by Blocking BMP6-Induced Th1

J. Li, L. Wu, Y. Chen, Z. Yan, J. Fu, Z. Luo, J. Du, L. Guo, J. Xu & Y. Liu
T-cell dysfunction has been shown to play an important role in the pathogenesis of Sjögren’s syndrome (SS). In recent studies, the increased expression of BMP6 has been reported to be related to SS. However, the roles that BMP6 plays in immune homeostasis in the development of SS as well as the downstream signals activated by BMP6 remain unclear. In this study, we investigated the effects and molecular mechanisms of BMP6 on naive CD4+ T cells,...

sj-docx-1-jdr-10.1177_00220345221119710 – Supplemental material for Anticeramide Improves Sjögren’s Syndrome by Blocking BMP6-Induced Th1

J. Li, L. Wu, Y. Chen, Z. Yan, J. Fu, Z. Luo, J. Du, L. Guo, J. Xu & Y. Liu
Supplemental material, sj-docx-1-jdr-10.1177_00220345221119710 for Anticeramide Improves Sjögren’s Syndrome by Blocking BMP6-Induced Th1 by J. Li, L. Wu, Y. Chen, Z. Yan, J. Fu, Z. Luo, J. Du, L. Guo, J. Xu and Y. Liu in Journal of Dental Research

Proteome-wide analyses reveal diverse functions of protein acetylation and succinylation modifications in fast growing stolons of bermudagrass (Cynodon dactylon L.)

Bing Zhang, Zhuoting Chen, Qixue Sun & Jianxiu Liu
Abstract Background Bermudagrass (Cynodon dactylon L.) is an important warm-season turfgrass species with well-developed stolons, which lay the foundation for the fast propagation of bermudagrass plants through asexual clonal growth. However, the growth and development of bermudagrass stolons are still poorly understood at the molecular level. Results In this study, we comprehensively analyzed the acetylation and succinylation modifications of proteins in fast-growing stolons of the bermudagrass cultivar Yangjiang. A total of 4657 lysine acetylation sites...

Additional file 17 of Proteome-wide analyses reveal diverse functions of protein acetylation and succinylation modifications in fast growing stolons of bermudagrass (Cynodon dactylon L.)

Bing Zhang, Zhuoting Chen, Qixue Sun & Jianxiu Liu
Additional file 17: Table S10: Acetylation and succinylation modification of Histone proteins in bermudagrass stolon.

Additional file 18 of Proteome-wide analyses reveal diverse functions of protein acetylation and succinylation modifications in fast growing stolons of bermudagrass (Cynodon dactylon L.)

Bing Zhang, Zhuoting Chen, Qixue Sun & Jianxiu Liu
Additional file 18: Table S11: Primers used in this study.

Additional file 15 of Proteome-wide analyses reveal diverse functions of protein acetylation and succinylation modifications in fast growing stolons of bermudagrass (Cynodon dactylon L.)

Bing Zhang, Zhuoting Chen, Qixue Sun & Jianxiu Liu
Additional file 15: Table S8: Conserved acetylated proteins and acetylated sites in three grasses.

Additional file 15 of Proteome-wide analyses reveal diverse functions of protein acetylation and succinylation modifications in fast growing stolons of bermudagrass (Cynodon dactylon L.)

Bing Zhang, Zhuoting Chen, Qixue Sun & Jianxiu Liu
Additional file 15: Table S8: Conserved acetylated proteins and acetylated sites in three grasses.

A new 1,4-benzoxazine derivative produced by endophytic Colletotrichum gloeosporioides B-142

Bing Zhang, Zhi-pu Huang, Yu Si, Ke-tao Zhang, Xiao-rong Xu, Jian-hong Chen, Qing Zhao & Xiao-mei Zhang
Colletotrin A (1), a new 1,4-benzoxazine derivative, and eight known compounds, including two alkaloids (2-3), one acylamide (4), one benzaldehyde (5), and four sterols (6-9) were obtained from endophytic fungus Colletotrichum gloeosporioides B-142, which was isolated from Dracaena cochinchinensis. Among them, 1,2,3,4-tetrahydroquinoline-4,8-diol (2) was reported for the first time as natural product. The structure of compound 1 was elucidated with help of spectroscopic data including IR, UV, electronic circular dichroism (ECD) calculation, HRESIMS, 1D and...

A new 1,4-benzoxazine derivative produced by endophytic Colletotrichum gloeosporioides B-142

Bing Zhang, Zhi-pu Huang, Yu Si, Ke-tao Zhang, Xiao-rong Xu, Jian-hong Chen, Qing Zhao & Xiao-mei Zhang
Colletotrin A (1), a new 1,4-benzoxazine derivative, and eight known compounds, including two alkaloids (2-3), one acylamide (4), one benzaldehyde (5), and four sterols (6-9) were obtained from endophytic fungus Colletotrichum gloeosporioides B-142, which was isolated from Dracaena cochinchinensis. Among them, 1,2,3,4-tetrahydroquinoline-4,8-diol (2) was reported for the first time as natural product. The structure of compound 1 was elucidated with help of spectroscopic data including IR, UV, electronic circular dichroism (ECD) calculation, HRESIMS, 1D and...

Additional file 1 of A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes

Huishi Toh, Chentao Yang, Giulio Formenti, Kalpana Raja, Lily Yan, Alan Tracey, William Chow, Kerstin Howe, Lucie A. Bergeron, Guojie Zhang, Bettina Haase, Jacquelyn Mountcastle, Olivier Fedrigo, John Fogg, Bogdan Kirilenko, Chetan Munegowda, Michael Hiller, Aashish Jain, Daisuke Kihara, Arang Rhie, Adam M. Phillippy, Scott A. Swanson, Peng Jiang, Dennis O. Clegg, Erich D. Jarvis … & Yury V. Bukhman
Additional file 1: Figure S1. Venn diagram of gene lists linked to type 2 diabetes by different types of evidence. Figure S2. Heterozygosity inferred by comparing the paternal and maternal scaffolded contigs, shown on the paternal scaffolds. Figure S3. Length distributions of structural variants. Figure S4. Functional classification of duplicated genes. Figure S5. Sequence alignment of Nile rat Gckr proteins to 113 mammalian orthologs. Figure S6. Missing Nile rat Hadh gene present in alternate haplotype...

Food insecurity and brain health in adults: A systematic review

Alan J. McMichael, Bernadette McGuinness, Jinkook Lee, Hoang Van Minh, Jayne V. Woodside & Claire T. McEvoy
Food insecurity has been associated with adverse effects on physical health and well-being in both high and low-income countries, but effects on brain health are not clear. The purpose of this systematic review was to determine the relationship between food insecurity and important brain health outcomes in adults including depression, stroke, cognitive impairment and dementia. Electronic databases were searched to find studies which investigated relations between food insecurity and predefined brain health outcomes. Thirty studies...

Additional file 1 of A survey of resident physicians’ perceptions of competency-based education in standardized resident training in China: a preliminary study

Qi Chen, Ming Li, Na Wu, Xue Peng, GuangMin Tang, Heng Cheng, LiuLing Hu, Bin Yang & ZhongLi Liao
Additional file 1.

Additional file 1 of Application of pedicled greater omentum flap tamponade combined with laparoscopic fenestration in diaphragmatic hepatic cyst

Zujian Wu, Yun Chen, Ye Jin, Changfeng Liu, Yusu Liu & Bing Zhang
Supplementary Material 1: Video

Effects of transcutaneous electrical acupoint stimulation on upper-limb impairment after stroke: A randomized, controlled, single-blind trial

Hewei Wang, Yuzhi Xiang, Chuankai Wang, Yingying Wang, Shugeng Chen, Li Ding, Qiang Liu, Xiaowen Wang, Kun Zhao, Jie Jia & Yao Chen
ObjectiveTo evaluate the effects of transcutaneous electrical acupoint stimulation (TEAS) on upper limb motor recovery during post-stroke rehabilitation.DesignSingle-blind, randomized controlled trial.SettingFour inpatient rehabilitation facilities.SubjectsA total of 204 stroke patients with unilateral upper limb motor impairment were randomly 1:1 allocated to TEAS or sham TEAS group. Baseline demographic and clinical characteristics were comparable between the two groups.InterventionsBoth groups received conventional physical and occupational therapies. TEAS and sham TEAS therapy were administered to two acupoints (LI10 and...

Effective soil washing for Cu removal in industrial soil remediation

Ruzhuang Zhang, Ziqian Xu, Xingbin Fang & Ming Li
Soil contamination caused by heavy metals has become a serious environmental and health-related problem to human. Copper (Cu) is essential to human and plants in appropriate amount but toxicant if excessive. Although soil washing has been developed for a long time for heavy metal remediation, there are few studies focusing on Cu, especially in the case of extreme concentration of metal and dissolved organic matters (DOM). Thus, based on the literature reviews about soil washing,...

Additional file 1 of Unused opioid prescription prevalence after pediatric ambulatory surgery: a survey study

Anjali A. Dixit, Nhi Ho, Christina Inglis-Arkell, Catherine L. Chen, Marla Ferschl & Solmaz P. Manuel
Additional file 1: Supplementary Table 1. Characteristics of survey responders and non-responders

Unused opioid prescription prevalence after pediatric ambulatory surgery: a survey study

Anjali A. Dixit, Nhi Ho, Christina Inglis-Arkell, Catherine L. Chen, Marla Ferschl & Solmaz P. Manuel
Abstract Background Surgery is a risk factor for opioid initiation, persistent use, and subsequent misuse in pediatric patients. The objective of this study was to assess the rate of postoperative opioid prescribing and extent of unused opioid prescriptions on the first postoperative day after pediatric ambulatory surgery. Methods A telephone survey was administered on postoperative day 1 (POD1) to guardians of all pediatric patients who underwent ambulatory surgery at a single medical center. Participants were...

A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes

Huishi Toh, Chentao Yang, Giulio Formenti, Kalpana Raja, Lily Yan, Alan Tracey, William Chow, Kerstin Howe, Lucie A. Bergeron, Guojie Zhang, Bettina Haase, Jacquelyn Mountcastle, Olivier Fedrigo, John Fogg, Bogdan Kirilenko, Chetan Munegowda, Michael Hiller, Aashish Jain, Daisuke Kihara, Arang Rhie, Adam M. Phillippy, Scott A. Swanson, Peng Jiang, Dennis O. Clegg, Erich D. Jarvis … & Yury V. Bukhman
Abstract Background The Nile rat (Avicanthis niloticus) is an important animal model because of its robust diurnal rhythm, a cone-rich retina, and a propensity to develop diet-induced diabetes without chemical or genetic modifications. A closer similarity to humans in these aspects, compared to the widely used Mus musculus and Rattus norvegicus models, holds the promise of better translation of research findings to the clinic. Results We report a 2.5 Gb, chromosome-level reference genome assembly with...

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