406 Works

Additional file 8 of Proteome-wide analyses reveal diverse functions of protein acetylation and succinylation modifications in fast growing stolons of bermudagrass (Cynodon dactylon L.)

Bing Zhang, Zhuoting Chen, Qixue Sun & Jianxiu Liu
Additional file 8: Table S1: Statistics of peptide spectra obtained in this study.

Harmonized HRS COVID, Version A

Hunter Green, Jenny Wilkens, Codi Young & Jinkook Lee

Additional file 2 of A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes

Huishi Toh, Chentao Yang, Giulio Formenti, Kalpana Raja, Lily Yan, Alan Tracey, William Chow, Kerstin Howe, Lucie A. Bergeron, Guojie Zhang, Bettina Haase, Jacquelyn Mountcastle, Olivier Fedrigo, John Fogg, Bogdan Kirilenko, Chetan Munegowda, Michael Hiller, Aashish Jain, Daisuke Kihara, Arang Rhie, Adam M. Phillippy, Scott A. Swanson, Peng Jiang, Dennis O. Clegg, Erich D. Jarvis … & Yury V. Bukhman
Additional file 2: Supplementary Table 1. TOGA status of 18430 ancestral placental mammal genes in muroid rodent genome assemblies. Supplementary Table 2. Positively selected genes and their mutation tolerance in humans according to gnomAD.

Rapid and precise identification of bloodstream infections using a pre-treatment protocol combined with high-throughput multiplex genetic detection system

Jinghao Zhang, Feng Yang, Zhaoyang Sun, Yi Fang, Haowei Zhu, Dijun Zhang, Xianping Zeng, Wenjian Liu, Tao Liu, Yixin Liu, Wenjing Chi, Su Wang, Li Ding, Yong Wu, Yanmei Zhang & Hu Zhao
Abstract Background Bloodstream infection (BSI) is a life-threatening condition with high morbidity and mortality rates worldwide. Early diagnosis of BSI is critical to avoid the unnecessary application of antimicrobial agents and for proper treatment. However, the current standard methods based on blood culture are time-consuming, thus failing to provide a timely etiological diagnosis of BSI, and common PCR-based detection might be inhibited by matrix components. Methods The current study explored an integrated pre-analytical treatment protocol...

Rapid and precise identification of bloodstream infections using a pre-treatment protocol combined with high-throughput multiplex genetic detection system

Jinghao Zhang, Feng Yang, Zhaoyang Sun, Yi Fang, Haowei Zhu, Dijun Zhang, Xianping Zeng, Wenjian Liu, Tao Liu, Yixin Liu, Wenjing Chi, Su Wang, Li Ding, Yong Wu, Yanmei Zhang & Hu Zhao
Abstract Background Bloodstream infection (BSI) is a life-threatening condition with high morbidity and mortality rates worldwide. Early diagnosis of BSI is critical to avoid the unnecessary application of antimicrobial agents and for proper treatment. However, the current standard methods based on blood culture are time-consuming, thus failing to provide a timely etiological diagnosis of BSI, and common PCR-based detection might be inhibited by matrix components. Methods The current study explored an integrated pre-analytical treatment protocol...

Additional file 2 of Effects of qigong exercise on the physical and mental health of college students: a systematic review and Meta-analysis

Jianping Lin, Yi fang Gao, Yue Guo, Ming Li, Yuxiang Zhu, Ruoshi You, Shaoqing Chen & Shizhong Wang
Supplementary Material 2: Figure S2. Sensitivity analysis of the effect of Qigong interventions on anxiety

Effects of qigong exercise on the physical and mental health of college students: a systematic review and Meta-analysis

Jianping Lin, Yi fang Gao, Yue Guo, Ming Li, Yuxiang Zhu, Ruoshi You, Shaoqing Chen & Shizhong Wang
Abstract Background Physical and mental health problems are becoming more serious among college students due to lifestyle changes and increased academic stress. Qigong exercise has been regarded as a potentially effective intervention to improve the physical and mental health of college students. Methods Eleven databases were searched from their respective inception dates to April 2022. Relevant randomized controlled trials (RCTs) were included. Physical and psychological conditions, including limb muscle strength, flexibility, cardiorespiratory endurance, vital capacity,...

Circ_0001955 promotes the progression of non-small cell lung cancer via miR-769-5p/EGFR axis

Li Ding, Yinan Feng & Longguang Li
To elaborate on the role of circular RNA 0001955 (circ_0001955) on the proliferation and apoptosis of non-small cell lung cancer (NSCLC) cells and its underlying mechanism. Circ_0001955 expression in NSCLC was screened out through bioinformatics analysis based on GEO database. Circ_0001955, microRNA-769-5p (miR-769-5p), and epidermal growth factor receptor (EGFR) expression in NSCLC tissues and cell lines was examined using quantitative real-time PCR (qRT-PCR) and Western blot. Cell proliferation and apoptosis were examined using the CCK-8...

Impacts of menopause hormone therapy on mood disorders among postmenopausal women

P. Feng, L. Lin, Y. Wang, L. Chen, J. Min, Y. Xie, M. Liu, S. Wei, S. Lin & Q. Yu
This study aimed to explore the modulatory effects of menopause hormone therapy (MHT) on mood disorders among postmenopausal women. A cross-sectional study was conducted to recruit postmenopausal women, including patients (arranged MHT for over 3 years as the medication group) and non-MHT controls. All participants were asked to respond to the Center for Epidemiological Studies Depression Scale (CES-D) and Generalized Anxiety Disorder Screener (GAD-7) questionnaires to assess their depression and anxiety status. A total of...

Sex differences in moral judgements across 67 countries

Morteza Dehghani, Mohammad Atari, Mark Lai & Morteza Dehghani
Most of the empirical research on sex differences and cultural variations in morality has relied on within-culture analyses or small-scale cross-cultural data. To further broaden the scientific understanding of sex differences in morality, the current research relies on two international samples to provide the first large-scale examination of sex differences in moral judgements nested within cultures. Using a sample from 67 countries (Study 1; n = 336,691), we found culturally-variable sex differences in moral judgements,...

Platelet-derived growth factor AA-modified electrospun fibers promote tendon healing

Linyou Wang, Tiejun Yang, Li Ding, Xiao Ye & Liang Wu
Platelet-derived growth factor AA (PDGF-AA) is an important promoter of tissue injury repair and might be a candidate for improving the mechanical properties of repaired tendons. Here, we designed a PDGF-AA-modified poly(lactide-co-glycolide) acid (PLGA) electrospun fibers to promote tendon rehabilitation after injury. In the present study, we grafted PDGF-AA on the surface of PLGA. In structural experiments, we found that the hydrophilicity of PLGA containing PDGF-AA (PLGA-PDGF-AA) increased, but the strength of the material did...

Platelet-derived growth factor AA-modified electrospun fibers promote tendon healing

Linyou Wang, Tiejun Yang, Li Ding, Xiao Ye & Liang Wu
Platelet-derived growth factor AA (PDGF-AA) is an important promoter of tissue injury repair and might be a candidate for improving the mechanical properties of repaired tendons. Here, we designed a PDGF-AA-modified poly(lactide-co-glycolide) acid (PLGA) electrospun fibers to promote tendon rehabilitation after injury. In the present study, we grafted PDGF-AA on the surface of PLGA. In structural experiments, we found that the hydrophilicity of PLGA containing PDGF-AA (PLGA-PDGF-AA) increased, but the strength of the material did...

Supplemental Material - Platelet-derived growth factor AA-modified electrospun fibers promote tendon healing

Linyou Wang, Tiejun Yang, Li Ding, Xiao Ye & Liang Wu
Supplemental Material for Platelet-derived growth factor AA-modified electrospun fibers promote tendon healing by Linyou Wang, Tiejun Yang, Li Ding, Xiao Ye and Liang Wu in Journal of Biomaterials Applications

Additional file 2 of AQP5 complements LGR5 to determine the fates of gastric cancer stem cells through regulating ULK1 ubiquitination

Rou Zhao, Baoyu He, Qingli Bie, Jinghe Cao, Haoran Lu, Zhixin Zhang, Jing Liang, Li Wei, Huabao Xiong & Bin Zhang
Additional file 2: Supplementary Table 1. Sequences ofreal-time PCR primers. Supplementary Table 2. Primary Antibodies. Supplementary Table 3. Second Antibodies. Supplementary Table 4. ShRNA or siRNA Oligonucleotides. Supplementary Table 5. Tumorigenicityof knockdown AQP5 and control group. Supplementary Table 6. Tumorigenicity of knockdown AQP5 and control group. Supplementary Table 7. Tumorigenicityof knockdown AQP5 and LGR5. Supplementary Table 8. Differentially expressed genes between exogenousoverexpression of AQP5 and control group. Supplementary Table 9. Differentially expressed genes between exogenousoverexpression...

AQP5 complements LGR5 to determine the fates of gastric cancer stem cells through regulating ULK1 ubiquitination

Rou Zhao, Baoyu He, Qingli Bie, Jinghe Cao, Haoran Lu, Zhixin Zhang, Jing Liang, Li Wei, Huabao Xiong & Bin Zhang
Abstract Background Cancer stem cells (CSCs) are regarded as the "seed cells" for tumorigenesis, metastasis, recurrence and drug resistance. However, specific surface markers of CSCs of different origins have not been documented. Methods Single-cell sequencing was used to analyze the highly expressed genes in cancer stem cells of gastric cancer patients, and it was verified that AQP5 was specifically highly expressed in gastric cancer stem cells (GC-CSCs) in vivo and in vitro. The effect of...

Is self-reported depression, HIV status, COVID-19 health risk profile and SARS-CoV-2 exposure associated with difficulty in adhering to COVID-19 prevention measures among residents in West Africa?

Morenike Oluwatoyin Folayan, Roberto Ariel Abeldaño Zuniga, Giuliana Florencia Abeldaño, Mir Faeq Ali Quadri, Mohammed Jafer, Muhammad Abrar Yousaf, Passent Ellakany, Ntombifuthi Nzimande, Eshrat Ara, Nuraldeen Maher Al-Khanati, Zumama Khalid, Folake Lawal, Mark Roque, Joanne Lusher, Bamidele O. Popoola, Abeedha Tu-Allah Khan, Martin Amogre Ayanore, Balgis Gaffar, Jorma I. Virtanen, Nourhan M. Aly, Joseph Chukwudi Okeibunor, Maha El Tantawi & Annie Lu Nguyen
Abstract Background The aim of this study was to determine whether self-reported depression, coronavirus disease of 2019 (COVID-19) health risk profile, HIV status, and SARS-CoV-2 exposure were associated with the use of COVID-19 prevention measures. Methods This survey collected data electronically between June 29 and December 31, 2020 from a convenient sample of 5050 adults 18 years and above living in 12 West African countries. The dependent variables were: social distancing, working remotely, difficulty obtaining...

Data for: Occupancy–detection models with museum specimen data: Promise and pitfalls

Vaughn Shirey, Rassim Khelifa, Leithen M'Gonigle & Laura Melissa Guzman
Historical museum records provide potentially useful data for identifying drivers of change in species occupancy. However, because museum records are typically obtained via many collection methods, methodological developments are needed in order to enable robust inferences. Occupancy-detection models, a relatively new and powerful suite of statistical methods, are a potentially promising avenue because they can account for changes in collection effort through space and time. We use simulated datasets to identify how and when patterns...

Attitudes about involvement in hypothetical clinical trial protocols in Mexican and Mexican-American at risk for autosomal dominant Alzheimer’s disease

Angélica Zuno-Reyes, Esmeralda Matute, Karin Ernstrom, Mellissa Withers, Yaneth Rodriguez-Agudelo, Rema Raman & John M. Ringman
Abstract Background The enrollment into clinical trials of persons at risk for autosomal dominant Alzheimer’s disease (ADAD) in whom the onset of disease can be accurately predicted facilitates the interpretation of outcomes (e.g., biomarkers, treatment efficacy). Attitudes toward involvement in such studies are biased by intrinsic cultural and social characteristics. Our objective was to study how demographic factors such as country of residence, age, sex, schooling, parenthood, and urbanization affect attitudes towards participation in hypothetical...

Sclerostin antibody promotes bone formation through the Wnt/β-catenin signaling pathway in femoral trochlear after patellar instability

Chenyue Xu, Gang Ji, Xiaobo Chen, Lirong Yan, Tuwan Liang, Junle Liu & Fei Wang
The molecular mechanism of patellar instability (PI) remains unknown. The purpose of this study was to explore the function of SOST/sclerostin in PI and examine the effect of sclerostin antibody (Scl-Ab). We randomly divided 60 male 3-week-old C57Bl/6 mice into four groups: sham, PI, Scl-Ab intraperitoneal injection (Scl-Ab IP), Scl-Ab intraarticular injection (Scl-Ab IA). PI was established in the latter three groups. The Scl-Ab IP/IA groups were administered with an intraperitoneal/intraarticular Scl-Ab injection (100 mg/kg,...

Adaptive parameter of standard deviation enhances the power of noninvasive prenatal screens

Li Qu, Qixi Wu, Xiaoke Yang, Weiwei Wang, Bing Xu, Guangyu Shan, Lin Liang, Shaowei Wang & Jingbo Zhang
Traditional Z-test methods during noninvasive prenatal screens (NIPS) use the fixed parameter of standard deviation (SD), which ignores the influence of actual sequencing read counts of a sample on the results. The aim of this study is to eliminate the influence of the sequencing depth of individual samples on the results and enhance the power of NIPS. In this study, we propose an improved NIPS method, which calculates the SD in the Z-score process adaptively...

Evaluation of the impact of crop residue on fractional vegetation cover estimation by vegetation indices over conservation tillage cropland: a simulation study

Zewen Dai, Yanling Ding, Chi Xu, Yunchao Chen & Lin Liu
Accurate estimation of fractional vegetation cover (FVC) is of great significance to agricultural production. Crop residue management affect crop residue cover (CRC) over croplands. Crop and crop residue on the soil surface both contribute to overall canopy reflectance. Few studies, however, have examined the effect of crop residue on vegetation indices (VIs) and estimated FVC. The present study evaluated the response of eight commonly used VIs to crop residues and FVC uncertainty caused by crop...

Evaluation of the impact of crop residue on fractional vegetation cover estimation by vegetation indices over conservation tillage cropland: a simulation study

Zewen Dai, Yanling Ding, Chi Xu, Yunchao Chen & Lin Liu
Accurate estimation of fractional vegetation cover (FVC) is of great significance to agricultural production. Crop residue management affect crop residue cover (CRC) over croplands. Crop and crop residue on the soil surface both contribute to overall canopy reflectance. Few studies, however, have examined the effect of crop residue on vegetation indices (VIs) and estimated FVC. The present study evaluated the response of eight commonly used VIs to crop residues and FVC uncertainty caused by crop...

Adverse childhood experiences and binge-eating disorder in early adolescents

Jonathan Chu, Julia H. Raney, Kyle T. Ganson, Kelsey Wu, Ananya Rupanagunta, Alexander Testa, Dylan B. Jackson, Stuart B. Murray & Jason M. Nagata
Abstract Background Adverse childhood experiences (ACEs) are common and linked to negative health outcomes. Previous studies have found associations between ACEs and binge-eating disorder (BED), though they have mainly focused on adults and use cross-sectional data. The objective of this study was to examine the associations between ACEs and BED in a large, national cohort of 9–14-year-old early adolescents in the US. Methods We analyzed prospective cohort data from the Adolescent Brain Cognitive Development (ABCD)...

sj-docx-1-cix-10.1177_11769351221136056 – Supplemental material for Optimizing Drug Response Study Design in Patient-Derived Tumor Xenografts

Jessica Weiss, Nhu-An Pham, Melania Pintilie, Ming Li, Geoffrey Liu, Frances A Shepherd, Ming-Sound Tsao & Wei Xu
Supplemental material, sj-docx-1-cix-10.1177_11769351221136056 for Optimizing Drug Response Study Design in Patient-Derived Tumor Xenografts by Jessica Weiss, Nhu-An Pham, Melania Pintilie, Ming Li, Geoffrey Liu, Frances A Shepherd, Ming-Sound Tsao and Wei Xu in Cancer Informatics

sj-xlsx-2-cix-10.1177_11769351221136056 – Supplemental material for Optimizing Drug Response Study Design in Patient-Derived Tumor Xenografts

Jessica Weiss, Nhu-An Pham, Melania Pintilie, Ming Li, Geoffrey Liu, Frances A Shepherd, Ming-Sound Tsao & Wei Xu
Supplemental material, sj-xlsx-2-cix-10.1177_11769351221136056 for Optimizing Drug Response Study Design in Patient-Derived Tumor Xenografts by Jessica Weiss, Nhu-An Pham, Melania Pintilie, Ming Li, Geoffrey Liu, Frances A Shepherd, Ming-Sound Tsao and Wei Xu in Cancer Informatics

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