629 Works

Emergency department-based, nurse-initiated, serious illness conversation intervention for older adults: a protocol for a randomized controlled trial

Thidathit Prachanukool, Susan D. Block, Donna Berry, Rachel S. Lee, Sarah Rossmassler, Mohammad A. Hasdianda, Wei Wang, Rebecca Sudore, Mara A. Schonberg, James A. Tulsky & Kei Ouchi
Abstract Background Visits to the emergency department (ED) are inflection points in patients’ illness trajectories and are an underutilized setting to engage seriously ill patients in conversations about their goals of care. We developed an intervention (ED GOAL) that primes seriously ill patients to discuss their goals of care with their outpatient clinicians after leaving the ED. The aims of this study are (i) to test the impact of ED GOAL administered by trained nurses...

Additional file 3 of Genome-wide identification and characterization of lncRNAs in sunflower endosperm

Shuai Yu, Zhichao Zhang, Jing Li, Yanbin Zhu, Yanzhe Yin, Xiaoyu Zhang, Yuxin Dai, Ao Zhang, Cong Li, Yanshu Zhu, Jinjuan Fan, Yanye Ruan & Xiaomei Dong
Additional file 3: Table S3. GO Gene Ontology analysis of co-expressed protein-coding genes with all candidate lncRNAs.

Additional file 4 of Genome-wide identification and characterization of lncRNAs in sunflower endosperm

Shuai Yu, Zhichao Zhang, Jing Li, Yanbin Zhu, Yanzhe Yin, Xiaoyu Zhang, Yuxin Dai, Ao Zhang, Cong Li, Yanshu Zhu, Jinjuan Fan, Yanye Ruan & Xiaomei Dong
Additional file 4: Fig. S1. Expressed lncRNAs in two crosses.

Additional file 5 of Genome-wide identification and characterization of lncRNAs in sunflower endosperm

Shuai Yu, Zhichao Zhang, Jing Li, Yanbin Zhu, Yanzhe Yin, Xiaoyu Zhang, Yuxin Dai, Ao Zhang, Cong Li, Yanshu Zhu, Jinjuan Fan, Yanye Ruan & Xiaomei Dong
Additional file 5: Fig. S2. Expression levels of lncRNAs and PCgenes in sunflower endosperm.

Additional file 7 of Genome-wide identification and characterization of lncRNAs in sunflower endosperm

Shuai Yu, Zhichao Zhang, Jing Li, Yanbin Zhu, Yanzhe Yin, Xiaoyu Zhang, Yuxin Dai, Ao Zhang, Cong Li, Yanshu Zhu, Jinjuan Fan, Yanye Ruan & Xiaomei Dong
Additional file 7: Fig. S4. DNA methylation profiles of protein-coding genes (PCgenes) in sunflower endosperm from SY1.

Additional file 2 of Neomorphic DNA-binding enables tumor-specific therapeutic gene expression in fusion-addicted childhood sarcoma

Tilman L. B. Hölting, Florencia Cidre-Aranaz, Dana Matzek, Bastian Popper, Severin J. Jacobi, Cornelius M. Funk, Florian H. Geyer, Jing Li, Ignazio Piseddu, Bruno L. Cadilha, Stephan Ledderose, Jennifer Zwilling, Shunya Ohmura, David Anz, Annette Künkele, Frederick Klauschen, Thomas G. P. Grünewald & Maximilian M. L. Knott
Additional file 2: Additional Tables 1-5.

Fig. S1. Myelopoiesis in Tg(drl:hoxa9;hsp70:meis1) embryos receiving one time of HS induction or daily HS induction. Embryos were assayed by WISH for mpx at 5 dpf. ;Fig. S2. A subgroup of Tg(drl:hoxa9;hsp70:meis1) adult fish develops AML-like phenotypes after one time HS in the embryos.;Fig. S3. Flow cytometry assay of the whole kidney marrow cells in WT, Tg(drl:hoxa9) and Tg(drl:hoxa9;hsp70:meis1) adult fish.;Fig. S4. Genome-wide transcriptional analysis of the kidney marrow cell of WT and Tg(drl:hoxa9;hsp70:meis1) adult fish.;Fig. S5. May-Grünwald and Giemsa staining of the peripheral blood cells from 7-dpf Tg(drl:hoxa9;hsp70:meis1) embryos with or without Lef treatment.

Wei Wang, Hongji Li, Mengling Huang, Xue Wang, Wei Li, Xiaoqing Qian & Lili Jing
Fig. S1. Myelopoiesis in Tg(drl:hoxa9;hsp70:meis1) embryos receiving one time of HS induction or daily HS induction. Embryos were assayed by WISH for mpx at 5 dpf. HS, heat-shock; NS, no statistical significance. ;Fig. S2. A subgroup of Tg(drl:hoxa9;hsp70:meis1) adult fish develops AML-like phenotypes after one time HS in the embryos. Tg(drl:hoxa9;hsp70:meis1) embryos were HS induced at 24 hpf once and grown to adulthood. (A) May-Grünwald/Giemsa staining of the whole kidney marrow blood cells and peripheral...

sj-xlsx-4-tct-10.1177_15330338221124658 - Supplemental material for In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells

Mike Y. Chen, Jing Li, Nianli Zhang, Erik I. Waldorff, James T. Ryaby, Philip Fedor, Yongsheng Jia & Yujun Wang
Supplemental material, sj-xlsx-4-tct-10.1177_15330338221124658 for In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells by Mike Y. Chen, Jing Li, Nianli Zhang and Erik I. Waldorff, James T. Ryaby, Philip Fedor, Yongsheng Jia, Yujun Wang in Technology in Cancer Research & Treatment

sj-xlsx-4-tct-10.1177_15330338221124658 - Supplemental material for In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells

Mike Y. Chen, Jing Li, Nianli Zhang, Erik I. Waldorff, James T. Ryaby, Philip Fedor, Yongsheng Jia & Yujun Wang
Supplemental material, sj-xlsx-4-tct-10.1177_15330338221124658 for In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells by Mike Y. Chen, Jing Li, Nianli Zhang and Erik I. Waldorff, James T. Ryaby, Philip Fedor, Yongsheng Jia, Yujun Wang in Technology in Cancer Research & Treatment

In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells

Mike Y. Chen, Jing Li, Nianli Zhang, Erik I. Waldorff, James T. Ryaby, Philip Fedor, Yongsheng Jia & Yujun Wang
Introduction: Although there have been significant advances in research and treatments over the past decades, cancer remains a leading cause of morbidity and mortality, mostly due to resistance to standard therapies. Pulsed electromagnetic field (PEMF), a newly emerged therapeutic strategy, has been highly regarded as less invasive and almost safe to patients, is now a clinically accepted form to treat diseases including cancer. Breast and lung cancer are the most prevalent forms of human cancers,...

sj-docx-1-cat-10.1177_10760296221132551 - Supplemental material for Prescribing Trends of Oral Anticoagulants from 2010 to 2020 in Shanghai, China: A Retrospective Study

Chi Zhang, Jia Wang, Ya Yang, Er-Li Ma, Hou-Wen Lin, Bing-Long Liu & Zhi-Chun Gu
Supplemental material, sj-docx-1-cat-10.1177_10760296221132551 for Prescribing Trends of Oral Anticoagulants from 2010 to 2020 in Shanghai, China: A Retrospective Study by Chi Zhang, Jia Wang, Ya Yang, Er-Li Ma, Hou-Wen Lin, Bing-Long Liu and Zhi-Chun Gu in Clinical and Applied Thrombosis/Hemostasis

Prescribing Trends of Oral Anticoagulants from 2010 to 2020 in Shanghai, China: A Retrospective Study

Chi Zhang, Jia Wang, Ya Yang, Er-Li Ma, Hou-Wen Lin, Bing-Long Liu & Zhi-Chun Gu
AimNon-vitamin K antagonist oral anticoagulants (NOACs) were developed as an alternative to warfarin to prevent thromboembolism in patients with atrial fibrillation (AF), prosthetic heart valves, venous thromboembolism (VTE), or other thrombotic disorders. The aim of this study is to explore the trends in prescribing OACs, including warfarin and NOACs, in Shanghai, China.MethodsPrescription data of OACs were retrospectively collected from Rx Analysis System from 2010 to 2020 in Shanghai, China. Comparisons were made on the trends...

Prescribing Trends of Oral Anticoagulants from 2010 to 2020 in Shanghai, China: A Retrospective Study

Chi Zhang, Jia Wang, Ya Yang, Er-Li Ma, Hou-Wen Lin, Bing-Long Liu & Zhi-Chun Gu
AimNon-vitamin K antagonist oral anticoagulants (NOACs) were developed as an alternative to warfarin to prevent thromboembolism in patients with atrial fibrillation (AF), prosthetic heart valves, venous thromboembolism (VTE), or other thrombotic disorders. The aim of this study is to explore the trends in prescribing OACs, including warfarin and NOACs, in Shanghai, China.MethodsPrescription data of OACs were retrospectively collected from Rx Analysis System from 2010 to 2020 in Shanghai, China. Comparisons were made on the trends...

The impact of circadian rhythms on the immune response to influenza vaccination in middle-aged and older adults (IMPROVE): a randomised controlled trial

Yihao Liu, Hui Zhang, Gang Yuan, Mi Yao, Bin Li, Jianying Chen, Yuling Fan, Ruohui Mo, Fenghua Lai, Xinwen Chen, Mengyuan Li, Binfeng Chen, Janet M. Lord, Sui Peng, KarKeung Cheng & Haipeng Xiao
Abstract Background Vaccination is important in influenza prevention but the immune response wanes with age. The circadian nature of the immune system suggests that adjusting the time of vaccination may provide an opportunity to improve immunogenicity. Our previous cluster trial in Birmingham suggested differences between morning and afternoon vaccination for some strains in the influenza vaccine in older adults. Whether this effect is also seen in a younger age group with less likelihood of compromised...

Additional file 15 of Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop

Yongzhen Mo, Yumin Wang, Yian Wang, Xiangying Deng, Qijia Yan, Chunmei Fan, Shuai Zhang, Shanshan Zhang, Zhaojian Gong, Lei Shi, Qianjin Liao, Can Guo, Yong Li, Guiyuan Li, Zhaoyang Zeng, Weihong Jiang, Wei Xiong & Bo Xiang
Additional file 15: Figure S6. circPVT1 promotes the migration and invasion of NPC cells by regulating cell adhesion andcytoskeleton remodeling. The 231 differentially expressed proteins regulated by c-Myc from LC-MS/MS data using the Ingenuity Pathway Analysis (IPA) software.

Clinical evaluation of AI software for rib fracture detection and its impact on junior radiologist performance

Xiang Liu, Dijia Wu, Huihui Xie, Yufeng Xu, Lin Liu, Xiaofeng Tao & Xiaoying Wang
BackgroundThe detection of rib fractures (RFs) on computed tomography (CT) images is time-consuming and susceptible to missed diagnosis. An automated artificial intelligence (AI) detection system may be helpful to improve the diagnostic efficiency for junior radiologists.PurposeTo compare the diagnostic performance of junior radiologists with and without AI software for RF detection on chest CT images.Materials and methodsSix junior radiologists from three institutions interpreted 393 CT images of patients with acute chest trauma, with and without...

Association between hyperglycemia on admission and preoperative deep venous thrombosis in patients with femoral neck fractures

Wei Yao, Wanyun Tang, Wei Wang, Qiaomei Lv & Wenbo Ding
Abstract Background Elevated blood glucose is the most frequent electrolyte disturbance in acutely ill patients. This study aimed to determine whether admission hyperglycemia is associated with the incidence of preoperative deep venous thrombosis (DVT) in patients with femoral neck fractures. Methods This retrospective study was conducted on consecutive patients with femoral neck fractures admitted to our institution from March 2018 to March 2022. Blood glucose levels were measured within 24 h of admission and categorized...

Additional file 1 of Association between hyperglycemia on admission and preoperative deep venous thrombosis in patients with femoral neck fractures

Wei Yao, Wanyun Tang, Wei Wang, Qiaomei Lv & Wenbo Ding
Additional file1: eFigure 1. Flow chart of enrollment. eTable 1. Multivariate Analysis for preoperative deep venous thrombosis. eTable 2. Patient Characteristics Before and After Propensity Score Matching by Glucose Level (≥6.10 mmol/L and <6.10mmol/L). eTable 3. Patient Characteristics Before and After Propensity Score Matching by Glucose Level (Group1 [0.00-5.30] vs Group2 [5.30-5.70] mmol/L). eTable 4. Patient Characteristics Before and After Propensity Score Matching by Glucose Level (Group2 [5.30-5.70] vs Group3 [5.70-6.60] mmol/L). eTable 5. Patient...

Additional file 1 of Association between hyperglycemia on admission and preoperative deep venous thrombosis in patients with femoral neck fractures

Wei Yao, Wanyun Tang, Wei Wang, Qiaomei Lv & Wenbo Ding
Additional file1: eFigure 1. Flow chart of enrollment. eTable 1. Multivariate Analysis for preoperative deep venous thrombosis. eTable 2. Patient Characteristics Before and After Propensity Score Matching by Glucose Level (≥6.10 mmol/L and <6.10mmol/L). eTable 3. Patient Characteristics Before and After Propensity Score Matching by Glucose Level (Group1 [0.00-5.30] vs Group2 [5.30-5.70] mmol/L). eTable 4. Patient Characteristics Before and After Propensity Score Matching by Glucose Level (Group2 [5.30-5.70] vs Group3 [5.70-6.60] mmol/L). eTable 5. Patient...

RNA binding protein HuR protects against NAFLD by suppressing long noncoding RNA H19 expression

Yanyan Wang, Yun-Ling Tai, Grayson Way, Jing Zeng, Derrick Zhao, Lianyong Su, Xixian Jiang, Kaitlyn G. Jackson, Xuan Wang, Emily C. Gurley, Jinze Liu, Jinpeng Liu, Weidong Chen, Xiang-Yang Wang, Arun J. Sanyal, Phillip B. Hylemon & Huiping Zhou
Abstract Background NAFLD has become the most common chronic liver disease worldwide. Human antigen R (HuR), an RNA-binding protein, is an important post-transcriptional regulator. HuR has been reported as a key player in regulating lipid homeostasis in the liver and adipose tissues by using tissue-specific HuR knockout mice. However, the underlying mechanism by which hepatocyte-specific HuR regulates hepatic lipid metabolism under metabolic stress remains unclear and is the focus of this study. Methods Hepatocyte-specific HuR...

SOMAS

Peiyuan Gao, Amity Andersen, Jonathan Sepulveda, Gihan Panapitiya, Aaron Hollas, Emily Saldanha, Vijayakumar Murugesan & Wei Wang
SOMAS dataset and XYZ files

IMPROVING EXPLOSIVE BODY CAPACITY IN FEMALE SHORT TRACK SPEED SKATERS

Jianjun Li, Xinchao Ge & Yang Liu
ABSTRACT Introduction The peculiar characteristics of short track speed skating should be integrated into the psychology of competitions; it is considered that elite athletes engaged in this particular sport should have a healthy psychic condition. Objective Investigate the explosive power of female speed skaters in short track speed skating. Methods 10 key athletes from the national short track speed skating team were selected, and explosive power was tested by T-test, hexagonal test, and pro sensitivity...

Additional file 4 of Nitrogen, manganese, iron, and carbon resource acquisition are potential functions of the wild rice Oryza rufipogon core rhizomicrobiome

Jingjing Chang, Lei Tian, Marcio F.A. Leite, Yu Sun, Shaohua Shi, Shangqi Xu, Jilin Wang, Hongping Chen, Dazhou Chen, Jianfeng Zhang, Chunjie Tian & Eiko E. Kuramae
Additional file 4: Figure S2. The principal coordinate analysis (PCoA) of the (A) bacterial and (B) fungal communities in the rhizosphere of wild rice populations of the in situ natural reserves (ZTI, Zhangtang; AJSI, Anjiashan; STSI, Shuitaoshu) and ex situ (ZT, Zhangtang; AJS, Anjiashan; STS, Shuitaoshu).

Additional file 1 of Nitrogen, manganese, iron, and carbon resource acquisition are potential functions of the wild rice Oryza rufipogon core rhizomicrobiome

Jingjing Chang, Lei Tian, Marcio F.A. Leite, Yu Sun, Shaohua Shi, Shangqi Xu, Jilin Wang, Hongping Chen, Dazhou Chen, Jianfeng Zhang, Chunjie Tian & Eiko E. Kuramae
Additional file 1: Table S1. Statistics for the quality assessment of the sequencing data.

Nitrogen uptake and utilization of two maize hybrids with contrasting nitrogen use efficiencies depending on fertilization amount

Guodong Shao, Hao Cheng, Hongcui Dai, Hui Zhang, Juanjuan Ai, Kaichang Liu, Zongxin Li, Kazem Zamanian & Xin Qian
Splitting nitrogen (N) application is beneficial for achieving higher grain yields and N use efficiency (NUE), but the responses of N utilization efficiency of different maize cultivars to top-dressing N fertilizer rates are still unclear. This study investigated the effects of fertilization managements on N uptake and utilization derived from topdressing fertilizers of maize hybrids (Ludan981 and Denghai605) with contrasting NUEs. The N fate derived from topdressing fertilizer was determined using the 15N tracing method....

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