9 Works

GnRH deficient patients with congenital hypogonadotropic hypogonadism: Novel genetic findings in ANOS1, RNF216, WDR11, FGFR1, CHD7 and POLR3A genes

Vassos Neocleous, Pavlos Fanis, Meropi Toumba, George Tanteles, Melpo Schiza, Feride Cinarli, Nicolas Nicolaides, Anastasis Oulas, George Spyrou, Christos Mantzoros, Dimitrios Vlachakis, Nicos Skordis & Leonidas Phylactou
Background: Congenital hypogonadotropic hypogonadism (CHH) is a rare genetic disease caused by Gonadotropin-Releasing Hormone (GnRH) deficiency. So far a limited number of variants in several genes have been associated with the pathogenesis of the disease. In this original research and review manuscript the retrospective analysis of known variants in ANOS1 (KAL1), RNF216, WDR11, FGFR1, CHD7 and POLR3A genes is described, along with novel variants identified in patients with CHH by the present study. Methods: Seven...

Data from: Effects of gestational maternal undernutrition on growth, carcass composition and meat quality of rabbit offspring

George K. Symeon, Michael Goliomytis, Iosif Bizelis, George Papadomichelakis, Olga Pagonopoulou, Zafeiris Abas, Stelios G. Deligeorgis & Stella E. Chadio
An experiment was conducted in order to evaluate the effects of gestational undernutrition of rabbit does on growth, carcass composition and meat quality of the offsprings. Thirty primiparous non lactating rabbit does were artificially inseminated and randomly divided in three treatment groups: Control (C; fed to 100% of maintenance requirements throughout gestation, n = 10), early undernourished (EU; fed to 50% of maintenance requirements during days 7–19 of gestation, n = 10) and late undernourished...

Data from: Fitness costs of key point mutations that underlie acaricide target-site resistance in the two-spotted spider mite Tetranychus urticae

Sabina Bajda, Maria Riga, Nicky Wybouw, Stavrini Papadaki, Eleni Ouranou, Seyedeh Masoumeh Fotoukkiaii, John Vontas & Thomas Van Leeuwen
The frequency of insecticide/acaricide target-site resistance is increasing in arthropod pest populations and is typically underpinned by single point mutations that affect the binding strength between the insecticide/acaricide and its target-site. Theory predicts that although resistance mutations clearly have advantageous effects under the selection pressure of the insecticide/acaricide, they might convey negative pleiotropic effects on other aspects of fitness. If such fitness costs are in place, target-site resistance is thus likely to disappear in the...

Genetic diversity of alpine Dryas octopetala populations at their southern distribution limit in Europe

Georgios Varsamis, Theodora Merou, Eleftherios Karapatzak, Aristotelis Papageorgiou, Georgios Fotiadis & Spyros Tsiftsis
The alpine species Dryas octopetala is present in the northern part of Greece, where it forms isolated populations in three mountainous regions: Falakron, Tzena and Orvilos. This study aimed at estimating the intrapopulation genetic diversity and the overall genetic structure of these southernmost European populations. A total of 20 Randomly Amplified Polymorphic DNA (RAPD) markers were used for studying the genetic patterns of populations. RAPD marker profiles revealed population differentiation, with Orvilos being the most...

Data from: Predator size affects the intensity of mutual interference in a predatory mirid

Nikos Papanikolaou, Sofia Dervisoglou, Argyro Fantinou, Theodore Kypraios, Valmari Giakoumaki & Dionysios Perdikis
Interference competition occurs when access to an available resource is negatively affected by interactions with other individuals, where mutual interference involves individuals of the same species. The interactive phenomena among individuals may be size-dependent, since body size is a major factor that may alter prey consumption rates and ultimately the dynamics and structure of food webs. A study was initiated in order to evaluate the effect of mutual interference in the prey-specific attack rates and...

Impacts of beekeeping on wild bee diversity and pollination networks in the Aegean Archipelago

Amparo Lázaro, Andreas Mueller, Andreas Ebmer, Holger Dathe, Erwin Scheuchl, Maximilian Schwarz, Stephan Risch, Alain Pauly, Jelle Devalez, Thomas Tscheulin, Carmelo Gómez-Martínez, Evangelos Papas, John Pickering, Nickolas Waser & Theodora Petanidou
Maintaining the diversity of wild bees is a priority for preserving ecosystem function and promoting stability and productivity of agroecosystems. However, wild bee communities face many threats and beekeeping could be one of them, because honey bees may have a strong potential to outcompete wild pollinators when placed at high densities. Yet, we still know little about how beekeeping intensity affects wild bee diversity and their pollinator interactions. Here, we explore how honey bee density...

Pathogenic and low frequency variants in children with central precocious puberty

Vassos Neocleous, Pavlos Fanis, Meropi Toumba, Barbara Gorka, Ioanna Kousiappa, George Tanteles, Michalis Iasonides, Nicolas Nicolaides, Yiolanda Christou, Kyriaki Michailidou, Stella Nicolaou, Savvas Papacostas, Athanasios Christoforides, Andreas Kyriakou, Dimitrios Vlachakis, Nicos Skordis & Leonidas Phylactou
Background Central precocious puberty (CPP) due to premature activation of GnRH secretion results in early epiphyseal fusion and to a significant compromise in the achieved final adult height. CPP is usually idiopathic and is disproportionally observed in girls compared to boys. Currently, only few genetic determinants of children with CPP have been described and the role they exert on the development of the disorder. In this original study rare variants in MKRN3, DLK1, KISS1, KISS1R...

Data from: Genome-wide transcriptional signatures of migratory flight activity in a globally invasive insect pest

Christopher M. Jones, Alexie Papanicolaou, George K. Mironidis, John Vontas, Yihua Yang, Ka S. Lim, Kumar S. Singh, John G. Oakeshott, Christopher Bass, Jason W. Chapman & Chris Bass
Migration is a key life history strategy for many animals and requires a suite of behavioural, morphological and physiological adaptations which together form the ‘migratory syndrome’. Genetic variation has been demonstrated for many traits that make up this syndrome, but the underlying genes involved remain elusive. Recent studies investigating migration-associated genes have focussed on sampling migratory and nonmigratory populations from different geographic locations but have seldom explored phenotypic variation in a migratory trait. Here, we...

Data from: A critical analysis of the potential for EU Common Agricultural Policy measures to support wild pollinators on farmland

Lorna Cole, David Kleijn, Lynn Dicks, Jane Stout, Simon Potts, Matthias Albrecht, Mario Balzan, Ignasi Bartomeus, Penelope Bebeli, Danilo Bevk, Jacobus Biesmeijer, Róbert Chlebo, Anželika Dautartė, Nikolaos Emmanouil, Chris Hartfield, John Holland, Andrea Holzschuh, Nieke Knoben, Anikó Kovács-Hostyánszki, Yael Mandelik, Heleni Panou, Robert Paxton, Theodora Petanidou, Miguel Pinheiro De Carvalho, … & Jeroen Scheper
1. Agricultural intensification and associated loss of high-quality habitats are key drivers of insect pollinator declines. With the aim of decreasing the environmental impact of agriculture, the 2014 EU Common Agricultural Policy (CAP) defined a set of habitat and landscape features (Ecological Focus Areas: EFAs) farmers could select from as a requirement to receive basic farm payments. To inform the post-2020 CAP, we performed a European-scale evaluation to determine how different EFA options vary in...

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Affiliations

  • Agricultural University of Athens
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  • Cyprus Institute of Neurology and Genetics
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  • Democritus University of Thrace
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  • Institute of Molecular Biology and Biotechnology
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  • University of the Aegean
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  • National and Kapodistrian University of Athens
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  • Estación Biológica de Doñana
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  • International Hellenic University
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  • Ghent University
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