The benefit of kidney transplantation versus remaining on the waitlist depends on patients' baseline comorbidities: a retrospective studyElias David Neto, Andrea Valeria Andrade-Izquierdo, Jose Otto Reusing-Junior, Vivian Onusic, Fabiana Agena, Hélcio Rodrigues, Gislene Oliveira Bezerra, Francine Brambate Carvalhinho Lemos & Fábio Gerab
Background: Patients with end-stage renal disease present comorbidities that increase mortality risk on the waitlist and after kidney transplantation. This study aimed to determine the impact of baseline comorbidities on the risk of death after kidney transplantation compared to remaining on the waitlist. Methods: Records of waitlisted patients were retrospectively analyzed. Multivariable time-dependent Cox-regression model was used to determine the initial and the lowest relative hazard-risk of death (HRD) after exposure to kidney transplantation. Results:...
The impact of local population genetic background on the spread of the selfish element Medea-1 in red flour beetlesSarah Cash, Fred Gould, Marce Lorenzen & Michael Robert
Selfish genetic elements have been found in the genomes of many species, yet our understanding of their evolutionary dynamics is only partially understood. A number of distinct selfish Medea elements are naturally present in many populations of the red flour beetle (Tribolium castaneum). Although these Medea elements are predicted by models to increase in frequency within populations because any offspring of a Medea-bearing mother that do not inherit at least one Medea allele will die,...
Continued adaptation of C4 photosynthesis after an initial burst of changes in the Andropogoneae grassesMatheus Bianconi, Jan Hackel, Maria Vorontsova, Adriana Alberti, Watchara Arthan, Sean Burke, Melvin Duvall, Elizabeth Kellogg, Sébastien Lavergne, Michael McKain, Alexandre Meunier, Colin Osborne, Paweena Traiperm, Pascal-Antoine Christin & Guillaume Besnard
C4 photosynthesis is a complex trait that sustains fast growth and high productivity in tropical and subtropical conditions and evolved repeatedly in flowering plants. One of the major C4 lineages is Andropogoneae, a group of ~ 1,200 grass species that includes some of the world's most important crops and species dominating tropical and some temperate grasslands. Previous efforts to understand C4 evolution in the group have compared a few model C4 plants to distantly related...
Water availability drives above-ground biomass and bird richness in forest restoration plantings to achieve carbon and biodiversity co-benefitsValerie Hagger, Kerrie Wilson, Jacqueline England & John Dwyer
To combat global warming and biodiversity loss we require effective forest restoration that encourages recovery of species diversity and ecosystem function to deliver essential ecosystem services, such as biomass accumulation. Further, understanding how and where to undertake restoration to achieve carbon sequestration and biodiversity conservation would provide an opportunity to finance ecosystem restoration under carbon markets. We surveyed 30 native mixed-species plantings in subtropical forests and woodlands in Australia, and used structural equation modelling to...
Genome-wide association analysis reveals QTL and candidate mutations involved in white spotting in cattleSwati Jivanji, Gemma Worth, Thomas J. Lopdell, Anna Yeates, Christine Couldrey, Edwardo Reynolds, Kathryn Tiplady, Lorna McNaughton, Thomas J.J. Johnson, Stephen R Davis, Bevin Harris, Richard Spelman, Russell G Snell, Dorian Garrick & Mathew D. Littlejohn
Background White spotting of the coat is a characteristic trait of various domestic species including cattle and other mammals. It is a hallmark of Holstein-Friesian cattle, and several previous studies have detected genetic loci with major effects for white spotting in animals with Holstein-Friesian ancestry. Here, our aim was to better understand the underlying genetic and molecular mechanisms of white spotting, by conducting the largest mapping study for this trait in cattle, to date. Results...
Hospital Universitário da Universidade de São Paulo5
Donald Danforth Plant Science Center1
Centro Universitário da FEI1
Livestock Improvement Corporation1
Royal Botanic Gardens1
Northern Illinois University1
Grenoble Alpes University1
University of Toulouse II - Le Mirail1
Institut de Biologie Structurale1