20,636 Works

Data from: Bacterial adaptation to sublethal antibiotic gradients can change the ecological properties of multitrophic microbial communities

Ville-Petri Friman, Laura Melissa Guzman, Daniel C. Reuman, Thomas Bell & V.-P. Friman
Antibiotics leak constantly into environments due to widespread use in agriculture and human therapy. Although sublethal concentrations are well known to select for antibiotic-resistant bacteria, little is known about how bacterial evolution cascades through food webs, having indirect effect on species not directly affected by antibiotics (e.g. via population dynamics or pleiotropic effects). Here, we used an experimental evolution approach to test how temporal patterns of antibiotic stress, as well as migration within metapopulations, affect...

Google

Matthew Harvey

Google

Matthew Harvey

Data from: Saturating effects of species diversity on life-history evolution in bacteria

Francesca Fiegna, Thomas Scheuerl, Alejandra Moreno-Letelier, Thomas Bell & Timothy G. Barraclough
Species interactions can play a major role in shaping evolution in new environments. In theory, species interactions can either stimulate evolution by promoting coevolution or inhibit evolution by constraining ecological opportunity. The relative strength of these effects should vary as species richness increases, and yet there has been little evidence for evolution of component species in communities. We evolved bacterial microcosms containing between 1 and 12 species in three different environments. Growth rates and yields...

deposition 1

Matthew Harvey
my dfirst dep

Taxol

Henry Rzepa
Compounds derived from Taxol

Data from: Development of the corticospinal and callosal tracts from extremely premature birth up to 2 years of age

Rodrigo M. Braga, Elise Roze, Gareth Ball, Nazakat Merchant, Nora Tusor, Tomoki Arichi, David Edwards, Daniel Rueckert & Serena J. Counsell
White matter tracts mature asymmetrically during development, and this development can be studied using diffusion magnetic resonance imaging. The aims of this study were i. to generate dynamic population-averaged white matter registration templates covering in detail the period from 25 weeks gestational age to term, and extending to 2 years of age based on DTI and fractional anisotropy, ii. to produce tract-specific probability maps of the corticospinal tracts, forceps major and forceps minor using probabilistic...

11 water 6-311++G(d,p)

Henry Rzepa
Gaussian Calculation

No description

Matthew Harvey
Gaussian Calculation

No description

Matthew Harvey
Gaussian Calculation

No description

Matthew Harvey
Gaussian Calculation

No description

Matthew Harvey
Gaussian Calculation

hydronium hydroxide 6-311++G(d,p) C3 + 9H2O IRC recalc=all

Henry Rzepa
Gaussian Calculation

SOBWAH, XeF5 wfn DZP anion

Henry Rzepa
Gaussian Calculation

Data from: Divergent evolution peaks under intermediate population bottlenecks during bacterial experimental evolution

Tom Vogwill, Robyn L. Phillips, Danna R. Gifford & R. Craig MacLean
There is growing evidence that parallel molecular evolution is common, but its causes remain poorly understood. Demographic parameters such as population bottlenecks are predicted to be major determinants of parallelism. Here, we test the hypothesis that bottleneck intensity shapes parallel evolution by elucidating the genomic basis of adaptation to antibiotic-supplemented media in hundreds of populations of the bacterium Pseudomonas fluorescens Pf0-1. As expected, bottlenecking decreased the rate of phenotypic and molecular adaptation. Surprisingly, bottlenecking had...

B(NHMe)3 + RCO2H TS TZVPP, no PT

Henry Rzepa
Gaussian Calculation

Chemical Science and Data Repository Design

Henry Rzepa

11B NMR chemical shifts computed at the wB97XD/aug-cc-pvDZ/SCRF=solvent method.

Henry Rzepa
Calculated 11B NMR chemical shifts and measured values. NMR Spectra. Version 11 of the Mestrenova software is required to process these latter files, available from http://mestrelab.com/software/mnova/download/ Download the .mnpub signature file and load it into MestreNova to view the spectra. To view datasets obtained here, Mestrenova need not be licensed.

B_isoTS_CF3_1 (ts)

Bethan Coulson
Gaussian Calculation

isoEa_Product_1 (opt freq)

Bethan Coulson
Gaussian Calculation

Eb_Reactant_1 (opt freq)

Bethan Coulson
Gaussian Calculation

TS1_enolate_3 (opt modred)

Bethan Coulson
Gaussian Calculation

A hexagonal planar transition metal complex

Martí Garçon
Nature paper. PdMg hexagonal planar. Martí Garçon

12-epoxide product freq

Henry Rzepa
Gaussian Calculation

12 reactant ...HOMe x-ray conformation methanol Def2-TZVPPD freq

Henry Rzepa
Gaussian Calculation

Registration Year

  • 2023
    70
  • 2022
    2,866
  • 2021
    2,411
  • 2020
    2,571
  • 2019
    7,999
  • 2018
    1,445
  • 2017
    1,503
  • 2016
    1,646
  • 2015
    79
  • 2014
    22

Resource Types

  • Text
    11,024
  • Dataset
    8,771
  • Collection
    809
  • Image
    15
  • Other
    8
  • Report
    4
  • Audiovisual
    3
  • Model
    1
  • Output Management Plan
    1

Affiliations

  • Imperial College London
    20,635
  • University of Oxford
    93
  • Fudan University
    88
  • Zhejiang University
    80
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    70
  • Capital Medical University
    67
  • Sichuan University
    64
  • Southern Medical University
    55
  • Harvard University
    54
  • Peking University
    46