79 Works

deposition 1

Matthew Harvey
my dfirst dep

Google

Matthew Harvey

Google

Matthew Harvey

Taxol

Henry Rzepa
Compounds derived from Taxol

Bar boo baz

Matthew Harvey
test

dep 1

Matthew Harvey
this is my long description what i wrote in a text file hello

chemdraw

Matthew Harvey
chemdraw 2

Data from: Visual receptive field properties of neurons in the mouse lateral geniculate nucleus

Jiaying Tang, Silvia C. Ardila Jimenez, Subhojit Chakraborty & Simon R. Schultz
The lateral geniculate nucleus (LGN) is increasingly regarded as a “smart-gating” operator for processing visual information. Therefore, characterizing the response properties of LGN neurons will enable us to better understand how neurons encode and transfer visual signals. Efforts have been devoted to study its anatomical and functional features, and recent advances have highlighted the existence in rodents of complex features such as direction/orientation selectivity. However, unlike well-researched higher-order mammals such as primates, the full array...

Data from: Seasonal influenza vaccination delivery through community pharmacists in England: evaluation of the London pilot

Katherine Atkins, Albert Jan Van Hoek, Conall Watson, Marc Baguelin, Lethiwe Choga, Anika Patel, Thara Raj, Mark Jit & Ulla Griffiths
Objective: To evaluate the effectiveness and cost of the pan-London pharmacy initiative, a programme that allows administration of seasonal influenza vaccination to eligible patients at pharmacies. Design: We analysed 2013–15 data on vaccination uptake in pharmacies via the Sonar reporting system, and the total vaccination uptake via 2011–15 ImmForm GP reporting system data. We conducted an online survey of London pharmacists who participate in the programme to assess time use data, vaccine choice, investment costs,...

Data from: Saturating effects of species diversity on life-history evolution in bacteria

Francesca Fiegna, Thomas Scheuerl, Alejandra Moreno-Letelier, Thomas Bell & Timothy G. Barraclough
Species interactions can play a major role in shaping evolution in new environments. In theory, species interactions can either stimulate evolution by promoting coevolution or inhibit evolution by constraining ecological opportunity. The relative strength of these effects should vary as species richness increases, and yet there has been little evidence for evolution of component species in communities. We evolved bacterial microcosms containing between 1 and 12 species in three different environments. Growth rates and yields...

Data from: Limiting opportunities for cheating stabilizes virulence in insect parasitic nematodes

Ben Raymond & David Shapiro-Ilan
Cooperative secretion of virulence factors by pathogens can lead to social conflict when cheating mutants exploit collective secretion, but do not contribute to it. If cheats outcompete cooperators within hosts, this can cause loss of virulence. Insect parasitic nematodes are important biocontrol tools that secrete a range of significant virulence factors. Critically, effective nematodes are hard to maintain without live passage, which can lead to virulence attenuation. Using experimental evolution we tested whether social cheating...

Data from: Body mass estimates of an exceptionally complete Stegosaurus (Ornithischia: Thyreophora): comparing volumetric and linear bivariate mass estimation methods

Charlotte A. Brassey, Susannah Maidment, Paul Barrett & P. M. Barrett
Body mass is a key biological variable, but difficult to assess from fossils. Various techniques exist for estimating body mass from skeletal parameters, but few studies have compared outputs from different methods. Here, we apply several mass estimation methods to an exceptionally complete skeleton of the dinosaur Stegosaurus. Applying a volumetric convex-hulling technique to a digital model of Stegosaurus, we estimate a mass of 1560 kg (95% prediction interval 1082–2256 kg) for this individual. By...

Data from: Bacterial adaptation to sublethal antibiotic gradients can change the ecological properties of multitrophic microbial communities

Ville-Petri Friman, Laura Melissa Guzman, Daniel C. Reuman, Thomas Bell & V.-P. Friman
Antibiotics leak constantly into environments due to widespread use in agriculture and human therapy. Although sublethal concentrations are well known to select for antibiotic-resistant bacteria, little is known about how bacterial evolution cascades through food webs, having indirect effect on species not directly affected by antibiotics (e.g. via population dynamics or pleiotropic effects). Here, we used an experimental evolution approach to test how temporal patterns of antibiotic stress, as well as migration within metapopulations, affect...

Data from: Development of the corticospinal and callosal tracts from extremely premature birth up to 2 years of age

Rodrigo M. Braga, Elise Roze, Gareth Ball, Nazakat Merchant, Nora Tusor, Tomoki Arichi, David Edwards, Daniel Rueckert & Serena J. Counsell
White matter tracts mature asymmetrically during development, and this development can be studied using diffusion magnetic resonance imaging. The aims of this study were i. to generate dynamic population-averaged white matter registration templates covering in detail the period from 25 weeks gestational age to term, and extending to 2 years of age based on DTI and fractional anisotropy, ii. to produce tract-specific probability maps of the corticospinal tracts, forceps major and forceps minor using probabilistic...

Computation data for Henry Rzepa's blog

Henry Rzepa
Ancillary files for Blog at at http://www.ch.ic.ac.uk/rzepa/blog/

Entry 1

Matthew Harvey
entry 1 in a test collection

Entry 2

Matthew Harvey
Test entry # 2

Taxol

Henry Rzepa
Atropisomerism in Taxol intermediates

foo

Matthew Harvey
a dummy foo

bar

Matthew Harvey
a dummy bar

chemdraw test

Matthew Harvey
my first chemdraw submission

chemdraw test

Matthew Harvey
my first chemdraw submission

Data from: Epidemiological interactions between urogenital and intestinal human schistosomiasis in the context of praziquantel treatment across three West African countries

Sarah C. L. Knowles, Bonnie L. Webster, Amadou Garba, Moussa Sacko, Oumar T. Diaw, Alan Fenwick, David Rollinson & Joanne P. Webster
Background: In many parts of sub-Saharan Africa, urogenital and intestinal schistosomiasis co-occur, and mixed species infections containing both Schistosoma haematobium and S. mansoni can be common. During co-infection, interactions between these two species are possible, yet the extent to which such interactions influence disease dynamics or the outcome of control efforts remains poorly understood. Methodology/Principal Findings: Here we analyse epidemiological data from three West African countries co-endemic for urogenital and intestinal schistosomiasis (Senegal, Niger and...

Data from: Bacterial cooperation causes systematic errors in pathogen risk assessment due to the failure of the independent action hypothesis

Daniel M. Cornforth, Andrew Matthews, Sam P. Brown & Ben Raymond
The Independent Action Hypothesis (IAH) states that pathogenic individuals (cells, spores, virus particles etc.) behave independently of each other, so that each has an independent probability of causing systemic infection or death. The IAH is not just of basic scientific interest; it forms the basis of our current estimates of infectious disease risk in humans. Despite the important role of the IAH in managing disease interventions for food and water-borne pathogens, experimental support for the...

Registration Year

  • 2015
    79

Resource Types

  • Dataset
    70
  • Collection
    9

Affiliations

  • Imperial College London
    79
  • University of Oxford
    6
  • Natural History Museum
    3
  • University of Birmingham
    2
  • Institut National de Recherche en Santé Publique
    1
  • VU University Amsterdam
    1
  • London School of Hygiene & Tropical Medicine
    1
  • University of Sussex
    1
  • The University of Texas at Austin
    1
  • National Museums Scotland
    1