Additional file 2: Fig. S2: Morphological characteristics of flower organs at three flower developmental stages in three Camellia sinensis varieties. BY1 represents the C. sinensis cv. ‘BaiYe 1’, HJY represents the C. sinensis cv. ‘HuangJinYa’, SCZ represents the C. sinensis cv. ‘SuChaZao’, S1-S3 represent the three flower developmental stages.

Additional file 7: Table S4: Summary of RNA-Seq data and mapping metrics.

Abstract Background Catechol-O-methyltransferase (COMT) has been shown to influence clinical pain, descending modulation, and exercise-induced symptom worsening. COMT regulates nociceptive processing and inflammation, key pathophysiological features of Chronic Fatigue Syndrome and Fibromyalgia (CFS/FM). We aimed to determine the interactions between genetic and epigenetic mechanisms regulating COMT and its influence on inflammatory markers and symptoms in patients with CFS/FM. Methods. A case-control study with repeated-measures design was used to reduce the chance of false positive and...

Additional file 9: Figure S9. Genome-wide composition of blastocysts following multipolar zygotic division. Circos plots of six embryos that developed to the blastocyst stage following multipolar zygotic division in which each circle represents the interpreted genome constitution per chromosome (1 - X) of a sampled single cell. The interpreted genome spanning the largest part of the chromosome was chosen as overall interpretation per chromosome, as such, segmental chromosomal errors are not depicted. On the left...

Additional file 3. A3. Classification system for assessment of study methodologies.

Performance evaluation of localization algorithms in stochastic optical localization nanoscopy is necessary and important to applications. By simulation, a localization algorithm estimates a set of emitter locations from a simulated data movie, whose error in comparison with the set of true locations indicates the performance of the algorithm. Since the partition of estimated locations is unknown, the sample root mean square error (RMSE) cannot be computed and the universal root mean square minimum distance (RMSMD)...

Supplemental material, sj-docx-1-eeg-10.1177_15500594221138292 for Is There a Difference in EEG Characteristics in Acute, Chronic, and Experimentally Induced Musculoskeletal Pain States? a Systematic Review by Jerin Mathew, Tyson Michael Perez, Divya Bharatkumar Adhia, Dirk De Ridder and Ramakrishnan Mani in Clinical EEG and Neuroscience

Additional file 1: Figure S1. Sorting of CD4+ T cells in CD4+CD25+Foxp3+Treg cells and CD3+CD8− cells in CD3+CD8−IL-17+Th17 cells analyzed by flow cytometry. Fig. S1A is related to Fig. 1A; Fig. S1B is related to Fig. 2C; Fig. S1C is related to Fig. 4A.

Additional file 1: Figure S1. Sorting of CD4+ T cells in CD4+CD25+Foxp3+Treg cells and CD3+CD8− cells in CD3+CD8−IL-17+Th17 cells analyzed by flow cytometry. Fig. S1A is related to Fig. 1A; Fig. S1B is related to Fig. 2C; Fig. S1C is related to Fig. 4A.

Additional file 2: Supplementary Table 1. FiO2 during induction, maintenance, and emergence from anaesthesia by geographical regions.

Introduction:Prolonged cardiac monitoring (PCM) substantially improves the detection of subclinical atrial fibrillation (AF) among patients with history of ischemic stroke (IS), leading to prompt initiation of anticoagulants. However, whether PCM may lead to IS prevention remains equivocal.Patients and methods:In this systematic review and meta-analysis, randomized-controlled clinical trials (RCTs) reporting IS rates among patients with known cardiovascular risk factors, including but not limited to history of IS, who received PCM for more than 7 days versus...

Additional file 2. PCC voxelsR1.

Additional file 1. MCC voxelsR1.

Abstract Background The core intrinsic connectivity networks (core-ICNs), encompassing the default-mode network (DMN), salience network (SN) and central executive network (CEN), have been shown to be dysfunctional in individuals with internalizing disorders (IDs, e.g. major depressive disorder, MDD; generalized anxiety disorder, GAD; social anxiety disorder, SOC). As such, source-localized, closed-loop brain training of electrophysiological signals, also known as standardized low-resolution electromagnetic tomography (sLORETA) neurofeedback (NFB), targeting key cortical nodes within these networks has the potential...

Additional file 1. Survey questions extracted from the original INSPIRE Population Survey (translated from German) (Siqeca et al., 2021).

Additional file 2. INSPIRE population survey respondents and dichotomized responses by content domain.

Additional file 3. Example Questions from the Interview Guide used in the INSPIRE parent study (translated from German) (Esser et al., 2022).

Additional file 5. Concepts related to care and support of frail older adults in 2018 and preferences for future, mapped to adapted domains of the SELFIE framework, including only respondents who indicated no current use for each question respectively, but responded for future preferences.

Additional file 5. Concepts related to care and support of frail older adults in 2018 and preferences for future, mapped to adapted domains of the SELFIE framework, including only respondents who indicated no current use for each question respectively, but responded for future preferences.

Abstract Background Home-dwelling frail older adults are often faced with multimorbidity and complex care needs, requiring health and social care systems that support frail older adults to age in place. The objective of this paper was to investigate the types of formal health and social care as well as informal care and social support used by home-dwelling frail older adults; whether they perceive their support as sufficient; and their experience with and preferences for care...

This study explored the function and mechanisms of HOX transcript antisense RNA (HOTAIR) in the drug resistance of nasopharyngeal carcinoma (NPC). Quantitative PCR, Western blotting, MTT assay, flow cytometry, Transwell assay, and luciferase assay were performed. HOTAIR expression levels were upregulated in cisplatin (DDP)-resistant NPC tissues and cells. Knockdown of HOTAIR in DDP-resistant NPC cells increased cell sensitivity of DDP, as well as decreased cell viability, expression of chemoresistance-related proteins, migration and invasion, increased cell...

Various methods exist for the induction of labor (IOL), and there is limited consensus as to optimal methods. Off-label misoprostol is recommended by the World Health Organization (WHO) for IOL but preparing it into doses suitable for IOL lacks precision, with potential adverse outcomes if dosing is inaccurate. This study explores potential outcomes and costs associated with increased uptake of a low-dose (25 µg) oral misoprostol formulation1 approved for IOL, in France, Belgium and the...

Additional file 1: Figure S2. Sorting of CD4+ T cells in CD4+CD25+Foxp3+Treg cells and CD3+CD8− cells in CD3+CD8−IL-17+Th17 cells analyzed by flow cytometry. Fig. S2 is related to Fig. 5A.

Additional file 2: Table S1. Description of the studies included in the analyses.

Additional file 1: Table S3. Patient and primary breast cancer characteristics per study.