2 Works

Data from: Reconstructing the microbial diversity and function of pre-agricultural tallgrass prairie soils in the United States

Noah Fierer, Joshua Ladau, Jose C. Clemente, Jonathan W. Leff, Sarah M. Owens, Katherine S. Pollard, Rob Knight, Jack A. Gilbert & Rebecca L. McCulley
Native tallgrass prairie once dominated much of the midwestern United States, but this biome and the soil microbial diversity that once sustained this highly productive system have been almost completely eradicated by decades of agricultural practices. We reconstructed the soil microbial diversity that once existed in this biome by analyzing relict prairie soils and found that the biogeographical patterns were largely driven by changes in the relative abundance of Verrucomicrobia, a poorly studied bacterial phylum...

Data from: Non-industry sponsored preclinical studies on statins yield greater efficacy estimates than industry-sponsored studies: a meta-analysis

David Krauth, Andrew Anglemyer, Rose Philipps & Lisa Bero
Industry-sponsored clinical drug studies are associated with publication of outcomes that favor the sponsor, even when controlling for potential bias in the methods used. However, the influence of sponsorship bias has not been examined in preclinical animal studies. We performed a meta-analysis of preclinical statin studies to determine whether industry sponsorship is associated with either increased effect sizes of efficacy outcomes and / or risks of bias in a cohort of published preclinical statin studies....

Registration Year

  • 2013
    2

Resource Types

  • Dataset
    2

Affiliations

  • University of California, San Francisco
    2
  • University of Kentucky
    1
  • Icahn School of Medicine at Mount Sinai
    1
  • University of Colorado Colorado Springs
    1
  • Argonne National Laboratory
    1