Data from: Gene duplication and divergence produce divergent MHC genotypes without disassortative mating

Donald C. Dearborn, Andrea B. Gager, Andrew G. McArthur, Morgan E. Gilmour, Elena Mandzhukova & Robert A. Mauck
Genes of the major histocompatibility complex (MHC) exhibit heterozygote advantage in immune defence, which in turn can select for MHC-disassortative mate choice. However, many species lack this expected pattern of MHC-disassortative mating. A possible explanation lies in evolutionary processes following gene duplication: if two duplicated MHC genes become functionally diverged from each other, offspring will inherit diverse multilocus genotypes even under random mating. We used locus-specific primers for high-throughput sequencing of two expressed MHC Class...

Registration Year

  • 2016
    1

Resource Types

  • Dataset
    1

Affiliations

  • Bates College
    1
  • McMaster University
    1
  • Cardiff University
    1
  • Kenyon College
    1