939 Works

Expansion of non-native plant Flaveria bidentis (L.) Kuntze driven by range of factors leading to patchy distribution patterns

Qianmei Wu, Chengdong Xu, Jiamei Li, Wanxue Liu, Fanghao Wan, Jianying Guo & Rui Wang
Given the growing concern over the ecological impacts of non-native species, exploring these species’ expansion edge and distribution patterns and their driving factors is important for developing suitable management measures. Flaveria bidentis (L.) Kuntze, a non-native plant that was introduced to China in the 1990s, has spread from southern Hebei Province, where it first took root, to the surrounding regions and has become one of the most notorious invasive weeds in northern China. Based on...

Additional file 1 of miR-351 promotes atherosclerosis in diabetes by inhibiting the ITGB3/PIK3R1/Akt pathway and induces endothelial cell injury and lipid accumulation

Hong Li, Dan Song, Qihui Liu, Linlin Li, Xiaoshi Sun, Jiamei Guo, Dianlian Li & Ping Li
Additional file 1. qPCR primer design. Design of mmu-mir-351silent primers. Itgb3 siRNA primer sequence design. Design of dual luciferaseactivity reporting primers.

Oxidative stress genes in patients with esophageal squamous cell carcinoma: construction of a novel prognostic signature and characterization of tumor microenvironment infiltration

Wei Liu, Hao-Shuai Yang, Shao-Yi Zheng, Hong-He Luo, Yan-Fen Feng & Yi-Yan Lei
Abstract Background Oxidative stress plays an important role in the progression of various types of tumors. However, its role in esophageal squamous cell carcinoma (ESCC) has seldom been explored. This study aimed to discover prognostic markers associated with oxidative stress in ESCC to improve the prediction of prognosis and help in the selection of effective immunotherapy for patients. Results A consensus cluster was constructed using 14 prognostic differentially expressed oxidative stress-related genes (DEOSGs) that were...

sj-pptx-2-tag-10.1177_17562848221124029 – Supplemental material for ‘FLARE’ of tumor marker in advanced gastric cancer treated with first-line systemic therapy

Fangyuan Zhang, Menglan Zhai, Jinru Yang, Lei Zhao, Zhenyu Lin, Jing Wang, Tao Zhang & Dandan Yu
Supplemental material, sj-pptx-2-tag-10.1177_17562848221124029 for ‘FLARE’ of tumor marker in advanced gastric cancer treated with first-line systemic therapy by Fangyuan Zhang, Menglan Zhai, Jinru Yang, Lei Zhao, Zhenyu Lin, Jing Wang, Tao Zhang and Dandan Yu in Therapeutic Advances in Gastroenterology

Additional file 3 of Metabolic profiling and pharmacokinetic studies of Baihu-Guizhi decoction in rats by UFLC-Q-TOF–MS/MS and UHPLC-Q-TRAP-MS/MS

Yan He, Zhenkun Zhou, Weijie Li, Yanqiong Zhang, Ruoyao Shi, Tao Li, Linlin Jin, Hongliang Yao, Na Lin & Hao Wu
Additional file 3: Figure S3. The chromatogram of selectivity of the analytes in rat serum.

Comparative clinical outcome following individualized follitropin delta dosing in Chinese women undergoing ovarian stimulation for in vitro fertilization /intracytoplasmic sperm injection

Rui Yang, Yunshan Zhang, Xiaoyan Liang, Xueru Song, Zhaolian Wei, Jianqiao Liu, Yezhou Yang, Jichun Tan, Qingxue Zhang, Yingpu Sun, Wei Wang, Weiping Qian, Lei Jin, Shuyu Wang, Yang Xu, Jing Yang, Marie Goethberg, Bernadette Mannaerts, Wen Wu, Zugeng Zheng & Jie Qiao
Abstract Background To compare the efficacy and safety of follitropin delta in its individualized fixed-dose regimen with follitropin alfa in a conventional adjustable dosing regimen in Chinese women. Methods This was a subgroup analysis of the randomized, multi-center, assessor-blind, non-inferiority trial (GRAPE) including 759 Chinese women (aged 20–40 years) recruited in 16 reproductive medicine clinics in China. Women were randomized in a 1:1 ratio to be treated with either follitropin delta dose based on anti-Müllerian...

Metabolic profiling and pharmacokinetic studies of Baihu-Guizhi decoction in rats by UFLC-Q-TOF–MS/MS and UHPLC-Q-TRAP-MS/MS

Yan He, Zhenkun Zhou, Weijie Li, Yanqiong Zhang, Ruoyao Shi, Tao Li, Linlin Jin, Hongliang Yao, Na Lin & Hao Wu
Abstract Background Baihu-Guizhi decoction (BHGZD) is a well-documented traditional Chinese Medicine (TCM) prescription that has been extensively applied to treating rheumatoid arthritis. Despite of its beneficial outcomes, the chemical constituents of BHGZD have not been fully portrayed and the in vivo absorption, distribution, metabolism, and excretion (ADME) patterns of absorbed components have never been described. Methods Characterization of absorbed components and in vivo biotransformation profiling of these feature compounds were based on the ultra-fast liquid...

Association between hyperglycemia on admission and preoperative deep venous thrombosis in patients with femoral neck fractures

Wei Yao, Wanyun Tang, Wei Wang, Qiaomei Lv & Wenbo Ding
Abstract Background Elevated blood glucose is the most frequent electrolyte disturbance in acutely ill patients. This study aimed to determine whether admission hyperglycemia is associated with the incidence of preoperative deep venous thrombosis (DVT) in patients with femoral neck fractures. Methods This retrospective study was conducted on consecutive patients with femoral neck fractures admitted to our institution from March 2018 to March 2022. Blood glucose levels were measured within 24 h of admission and categorized...

Additional file 1 of Estimating disability-adjusted life years for breast cancer and the impact of screening in female populations in China, 2015–2030: an exploratory prevalence-based analysis applying local weights

Xin-Xin Yan, Juan Zhu, Yan-Jie Li, Meng-Di Cao, Xin Wang, Hong Wang, Cheng-Cheng Liu, Jing Wang, Yang Li & Ju-Fang Shi
Additional file 1: Demographic, breast cancer epidemiological and screening factors of the female populations in China.

Additional file 4 of Estimating disability-adjusted life years for breast cancer and the impact of screening in female populations in China, 2015–2030: an exploratory prevalence-based analysis applying local weights

Xin-Xin Yan, Juan Zhu, Yan-Jie Li, Meng-Di Cao, Xin Wang, Hong Wang, Cheng-Cheng Liu, Jing Wang, Yang Li & Ju-Fang Shi
Additional file 4: Age-specific number of females and standardized life expectancy

Additional file 3 of Estimating disability-adjusted life years for breast cancer and the impact of screening in female populations in China, 2015–2030: an exploratory prevalence-based analysis applying local weights

Xin-Xin Yan, Juan Zhu, Yan-Jie Li, Meng-Di Cao, Xin Wang, Hong Wang, Cheng-Cheng Liu, Jing Wang, Yang Li & Ju-Fang Shi
Additional file 3: Age-specific incidence, mortality and survival rates of breast cancer.

Protective effects of psoralen polymer lipid nanoparticles on doxorubicin - induced myocardial toxicity

Fansu Meng, Yong Ouyang, Qianqian Ma, Manling Du, Hui Liu, Yong Zhuang, Mujuan Pang, Tiange Cai & Yu Cai
Abstract Doxorubicin (DOX) induced myocardial toxicity may limit its therapeutic use in clinic. Psoralen (PSO), a major active tricyclic furocoumarin extracted from Psoralea corylifolia, is widely used as an antineoplastic agent in treatment of leukemia and other cancers. This study is aim to find the protective effect of psoralen polymer lipid nanoparticles (PSO-PLN) on doxorubicin-induced myocardial toxicity in mice. The model of myocardial toxicity induced by DOX was established. The experiment was divided into 6...

Additional file 3 of Inhibition of CISD2 promotes ferroptosis through ferritinophagy-mediated ferritin turnover and regulation of p62–Keap1–NRF2 pathway

Yanchun Li, Bing Xu, Xueying Ren, Luyang Wang, Yaqing Xu, Yefeng Zhao, Chen Yang, Chen Yuan, Huanjuan Li, Xiangmin Tong, Ying Wang & Jing Du
Additional file 3: Figure S3. Quantitative analysis of FTH expression in Fig. 3B.

Additional file 3 of Oxidative stress genes in patients with esophageal squamous cell carcinoma: construction of a novel prognostic signature and characterization of tumor microenvironment infiltration

Wei Liu, Hao-Shuai Yang, Shao-Yi Zheng, Hong-He Luo, Yan-Fen Feng & Yi-Yan Lei
Additional file 3: Figure S1. (A, D, G) The heat map of 10 prognostic DEOSG expressions in the train (A), testing (D), and entire sets (G), respectively. (B, E, H) The comparison of 10 prognostic DEOSG expressions between high- and low-risk groups in the training (B), testing (E), and entire sets (H), respectively. (C, F, I) The correlations among 10 prognostic DEOSG between high- and low-risk groups in the training (C), testing (F), and entire...

Additional file 4 of Oxidative stress genes in patients with esophageal squamous cell carcinoma: construction of a novel prognostic signature and characterization of tumor microenvironment infiltration

Wei Liu, Hao-Shuai Yang, Shao-Yi Zheng, Hong-He Luo, Yan-Fen Feng & Yi-Yan Lei
Additional file 4: Table S3. The results of univariate Cox proportional hazards regression analyses between clinical features and risk score in the training, testing, and entire sets.

Additional file 5 of Oxidative stress genes in patients with esophageal squamous cell carcinoma: construction of a novel prognostic signature and characterization of tumor microenvironment infiltration

Wei Liu, Hao-Shuai Yang, Shao-Yi Zheng, Hong-He Luo, Yan-Fen Feng & Yi-Yan Lei
Additional file 5: Table S4. The results of univariate Cox proportional hazards regression analyses between clinical features and risk score in the training, testing, and entire sets.

Supplementary document for Quantum and quasi-classical effects in the strong field ionization and subsequent excitation of nitrogen molecules - 5939627.pdf

Liang Xu, Qi Lu, Vladimir Tikhonchuk, Bin Zhou, Runzhe Yang, Qingqing Liang, He Feng, Rostyslav Danylo, Aurelien Houard & Andre Mysyrowicz
Supplemental Document

Quantum and quasi-classical effects in the strong field ionization and subsequent excitation of nitrogen molecules

Liang Xu, Qi Lu, Vladimir Tikhonchuk, Bin Zhou, Runzhe Yang, Qingqing Liang, He Feng, Rostyslav Danylo, Aurelien Houard & Andre Mysyrowicz
The processes leading to the N2+ lasing are rather complex and even the population distribution after the pump laser excitation is unknown. In this paper, we study the population distribution at electronic and vibrational levels in N2+ driven by ultra-short laser pulse at the wavelengths of 800 nm and 400 nm by using the quantum-mechanical time-domain incoherent superposition model based on the time-dependent Schrodinger equation and the quasi-classical model assuming instantaneous ionization injection described by...

The bidirectional association of C-peptide with cardiovascular risk in nondiabetic adults and patients with newly diagnosed type 2 diabetes mellitus: a retrospective cohort study

Shuang-Tong Yan, Jing Sun, Zhao-Yan Gu, Xin-Yu Miao, Li-Chao Ma, Ban-Ruo Sun, Xiao-Min Fu, Hong-Zhou Liu, Guang Yang, Fu-Sheng Fang & Hong Li
Abstract Background Recent literature reported the biological role of C-peptide, but this role is still controversial and unclear. The primary aim of this study was to investigate associations between C-peptide and cardiovascular biomarkers as well as events. Methods A total of 55636 participants who had a health examination from 2017 to 2021 were included. Of them, 6727 participants visited the hospital at least twice. Cardiovascular biomarkers like high-sensitivity C-reactive protein (hs-CRP) and high-sensitivity cardiac troponin...

Additional file 1 of A machine learning-based data mining in medical examination data: a biological features-based biological age prediction model

Qing Yang, Sunan Gao, Junfen Lin, Ke Lyu, Zexu Wu, Yuhao Chen, Yinwei Qiu, Yanrong Zhao, Wei Wang, Tianxiang Lin, Huiyun Pan & Ming Chen
Additional file 1. Fig. S1. Optimized lambda selection (A) and feature selection (B) in Lasso regression. Fig. S2. Feature importance values in the Stacking model. Fig. S3. Schematic diagrams of the process for introducing missing values and interpolation in MCAR (A) and MNAR (B). Table S1. Parameter optimization results of KNN and MICE in MCAR. Table S2. Parameter optimization results of KNN and MICE in MNAR. Table S3. The optimized parameters of AE and RRLR....

Data from \" Chemical Origin of Temperature-Dependent Phase Transition and Conductivity in Hydroxyapatite\"

Dingguo Xu & Jing Wang
This dataset contains data relates to the publication " Chemical Origin of Temperature-Dependent Phase Transition and Conductivity in Hydroxyapatite", by Wang et al., 2022. In this work, we use deep potential molecular dynamics simulation to study Temperature-Dependent Phase Transition and Conductivity in Hydroxyapatite. The deep neural network potential is trained on DFT calculations. This dataset contains the deep potential models and the DFT training data reported in the publication, the input files of vasp, lammps,...

Additional file 1 of Alpha-ketoglutarate ameliorates abdominal aortic aneurysm via inhibiting PXDN/HOCL/ERK signaling pathways

Junjun Liu, Mingyuan Liu, Jiaxuan Feng, Hongqiao Zhu, Jianlie Wu, Heng Zhang, Shun Xiao, Zaiping Jing, Jian Zhou, Haitao Niu & Mingjin Guo
Additional file 1. AKG treatment in mice with the sham surgery did not affect abdominal aortic diameter.

Alpha-ketoglutarate ameliorates abdominal aortic aneurysm via inhibiting PXDN/HOCL/ERK signaling pathways

Junjun Liu, Mingyuan Liu, Jiaxuan Feng, Hongqiao Zhu, Jianlie Wu, Heng Zhang, Shun Xiao, Zaiping Jing, Jian Zhou, Haitao Niu & Mingjin Guo
Abstract Abdominal aortic aneurysm (AAA) represents the serious vascular degenerative disorder, which causes high incidence and mortality. Alpha-ketoglutarate (AKG), a crucial metabolite in the tricarboxylic acid (TCA) cycle, has been reported to exert significant actions on the oxidative stress and inflammation. However, its role in AAA still remains elusive. Herein, we examined the effects of AKG on the formation of AAA. The study established an elastase-induced mouse abdominal aortic aneurysms model as well as a...

Additional file 3 of Alpha-ketoglutarate ameliorates abdominal aortic aneurysm via inhibiting PXDN/HOCL/ERK signaling pathways

Junjun Liu, Mingyuan Liu, Jiaxuan Feng, Hongqiao Zhu, Jianlie Wu, Heng Zhang, Shun Xiao, Zaiping Jing, Jian Zhou, Haitao Niu & Mingjin Guo
Additional file 3. PXDN was overexpressed in aorta by the injection of a adenovirus harboring the PXDN gene.

Additional file 2 of Mediation analysis of erythrocyte lipophilic index on the association between BMI and risk of oral cancer

Yi Fan, Qing Chen, Yaping Wang, Jing Wang, Yanni Li, Sijie Wang, Yanfeng Weng, Qiujiao Yang, Chen Chen, Lisong Lin, Yu Qiu, Fa Chen, Baochang He & Fengqiong Liu
Additional file 2: Supplement Table 1. Multivariable generalized Linear Models of mediation of outcome models.

Registration Year

  • 2022
    939

Resource Types

  • Text
    372
  • Dataset
    221
  • Collection
    213
  • Image
    119
  • Audiovisual
    8
  • Other
    6

Affiliations

  • Henan Agricultural University
    939
  • Zhejiang University
    730
  • Sichuan University
    616
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    600
  • Capital Medical University
    589
  • Shanghai Jiao Tong University
    575
  • Fudan University
    564
  • Huazhong University of Science and Technology
    540
  • Southern Medical University
    490
  • Peking University
    489