84 Works

BEDMAP2 - Ice thickness, bed and surface elevation for Antarctica - standardised data points

Peter Fretwell, Alice Fremand, Julien Bodart, Hamish Pritchard, David Vaughan, Jonathan Bamber, N. Barrand, R.E. Bell, C Bianchi, Robert Bingham, Donald Blankenship, G. Casassa, Ginny Catania, D. Callens, H Conway, Alison Cook, Hugh Corr, D Damaske, V. Damn, Fausto Ferraccioli, Rene Forsberg, S. Fujita, Y. Gim, P. Gogineni, J. Griggs … & A. Zirizzotti
We present here the Bedmap2 ice thickness, bed and surface elevation standardised CSV data points that were used to create the Bedmap2 gridding products. The data consists of 25 million points coming from 68 individual surveys acquired in Antarctica. The associated datasets consist of: - Bedmap1 standardised CSV data points: https://doi.org/10.5285/f64815ec-4077-4432-9f55-0ce230f46029 - Bedmap3 standardised CSV data points: https://doi.org/10.5285/91523ff9-d621-46b3-87f7-ffb6efcd1847 - Bedmap2 statistically-summarised data points (shapefiles): https://doi.org/10.5285/0f90d926-99ce-43c9-b536-0c7791d1728b - Bedmap2 gridding products: https://doi.org/10.5285/fa5d606c-dc95-47ee-9016-7a82e446f2f2 This work is supported by...

Threshold of main pancreatic duct for malignancy in intraductal papillary mucinous neoplasm at head-neck and body-tail

Hao Zhou, Xiaoshuang Li, Yajie Wang, Zhiyue Wang, Jingrong Zhu, Zhongqiu Wang & Xiao Chen
Abstract Background Main pancreatic duct (MPD) dilation is a high-risk stigmata/worrisome feature of malignancy in intraductal papillary mucinous neoplasms (IPMNs). The threshold of MPD diameter in predicting malignancy may be related to the lesion location. This study aimed to separately identify the thresholds of MPD for malignancy of IPMNs separately for the head-neck and body-tail. Materials and methods A total of 185 patients with pathologically confirmed IPMNs were included. Patient demographic information, clinical data, and...

Additional file 1 of Metabolic engineering enables Bacillus licheniformis to grow on the marine polysaccharide ulvan

Theresa Dutschei, Marie-Katherin Zühlke, Norma Welsch, Tom Eisenack, Maximilian Hilkmann, Joris Krull, Carlo Stühle, Stefan Brott, Alexandra Dürwald, Lukas Reisky, Jan-Hendrik Hehemann, Dörte Becher, Thomas Schweder & Uwe T. Bornscheuer
Additional file 1: Table S1. Proteins and accession numbers. Table S2. Bacterial strains. Table S3. M9-mineral media d-glucose composition. Table S4. M9-mineral media additives. Table S5. Primer list. Figure S1. Sugar composition of the cultivation media. Figure S2. SDS-PAGE of F. agariphila KMM3901T enzymes expressed recombinantly in E. coli. Figure S3. Consumption of 5-dehydro-4-deoxy-d-glucuronate from B. licheniformis DSM13 during cultivation. Figure S4. Growth of B. licheniformis DSM13 on different ulvan hydrolysates. Figure S5. B. licheniformis...

Additional file 3 of Metabolic engineering enables Bacillus licheniformis to grow on the marine polysaccharide ulvan

Theresa Dutschei, Marie-Katherin Zühlke, Norma Welsch, Tom Eisenack, Maximilian Hilkmann, Joris Krull, Carlo Stühle, Stefan Brott, Alexandra Dürwald, Lukas Reisky, Jan-Hendrik Hehemann, Dörte Becher, Thomas Schweder & Uwe T. Bornscheuer
Additional file 3: Table S7. Results of statistical analyses.

Additional file 3 of Metabolic engineering enables Bacillus licheniformis to grow on the marine polysaccharide ulvan

Theresa Dutschei, Marie-Katherin Zühlke, Norma Welsch, Tom Eisenack, Maximilian Hilkmann, Joris Krull, Carlo Stühle, Stefan Brott, Alexandra Dürwald, Lukas Reisky, Jan-Hendrik Hehemann, Dörte Becher, Thomas Schweder & Uwe T. Bornscheuer
Additional file 3: Table S7. Results of statistical analyses.

A practical Alzheimer’s disease classifier via brain imaging-based deep learning on 85,721 samples

Bin Lu, Hui-Xian Li, Zhi-Kai Chang, Le Li, Ning-Xuan Chen, Zhi-Chen Zhu, Hui-Xia Zhou, Xue-Ying Li, Yu-Wei Wang, Shi-Xian Cui, Zhao-Yu Deng, Zhen Fan, Hong Yang, Xiao Chen, Paul M. Thompson, Francisco Xavier Castellanos & Chao-Gan Yan
Abstract Beyond detecting brain lesions or tumors, comparatively little success has been attained in identifying brain disorders such as Alzheimer’s disease (AD), based on magnetic resonance imaging (MRI). Many machine learning algorithms to detect AD have been trained using limited training data, meaning they often generalize poorly when applied to scans from previously unseen scanners/populations. Therefore, we built a practical brain MRI-based AD diagnostic classifier using deep learning/transfer learning on a dataset of unprecedented size...

Neighbourhood socio-economic status and positive affectivity among older residents in Germany: a cross-sectional analysis with data from the Heinz Nixdorf Recall Study

Christina Hartig, Gabriele Bolte, Karl-Heinz Jöckel, Susanne Moebus & Natalie Riedel
Abstract Background Physical and social neighbourhood characteristics can vary according to the neighbourhood socio-economic status (SES) and influence residents’ perceptions, behaviours and health outcomes both positively and negatively. Neighbourhood SES has been shown to be predictive of mental health, which is relevant for healthy ageing and prevention of dementia or depression. Positive affectivity (PA) is an established indicator of mental health and might indicate a positive emotional response to neighbourhood characteristics. In this study, we...

2020 TCCON Data Release

The Total Carbon Column Observing Network (TCCON) is a network of ground-based Fourier Transform Spectrometers that record direct solar absorption spectra of the atmosphere in the near-infrared. From these spectra, accurate and precise column-averaged abundances of atmospheric constituents including CO2, CH4, N2O, HF, CO, H2O, and HDO, are retrieved. This is the GGG2020 data release.

Clinical features of the first critical case of acute encephalitis caused by the avian influenza A (H5N6) virus

Libing Zhang, Kaituo Liu, Qin Su, Xiao Chen, Xiaoquan Wang, Qingfeng Li, Wenlei Wang, Xuhua Mao, Jinmei Xu, Xin Zhou, Qin Xu, Le Zhou, Xiufan Liu & Pinghu Zhang
Highly pathogenic avian influenza viruses (HPAIV), such as H5N1, H5N6, and H7N9, have been reported to frequently infect humans, but acute encephalitis caused by HPAIV in humans has been rarely reported. We report the first critical case of acute encephalitis with mild pneumonia caused by the H5N6 virus. On January 25 of 2022, a 6-year-old girl with severe neurological symptoms was admitted to our hospital and rapidly developed into seizures and coma. Brain imaging showed...

TCCON data from Orléans (FR), Release GGG2020.R0

T. Warneke, C. Petri, J. Notholt & M. Buschmann
The Total Carbon Column Observing Network (TCCON) is a network of ground-based Fourier Transform Spectrometers that record direct solar absorption spectra of the atmosphere in the near-infrared. From these spectra, accurate and precise column-averaged abundances of atmospheric constituents including CO2, CH4, N2O, HF, CO, H2O, and HDO, are retrieved. This is the GGG2020 data release of observations from the TCCON station at Orleans, France

The impact of variable Fe concentrations on Fe-binding ligands, dissolved organics and microbial communities in hydrothermal plumes – an experimental study

Christian Tobias Hansen, Charlotte Kleint , Stefanie Böhnke , Lukas Klose , Nicole Adam , Katharina Sass, Mirjam Perner , Thorsten Dittmar & Andrea Koschinsky
Iron (Fe) plays an important role in aquatic environments as an essential, often biolimiting micronutrient but at very high concentrations can potentially be toxic. Consequently, microbes have evolved capabilities to influence Fe bioavailability through production of organic molecules, so called ligands, which can enhance iron bioavailability or be used for detoxification mechanisms. Hydrothermal vents represent a major source of Fe to the oceans and host specialized microbes that are likely capable of influencing Fe speciation...

Additional file 2 of Metabolic engineering enables Bacillus licheniformis to grow on the marine polysaccharide ulvan

Theresa Dutschei, Marie-Katherin Zühlke, Norma Welsch, Tom Eisenack, Maximilian Hilkmann, Joris Krull, Carlo Stühle, Stefan Brott, Alexandra Dürwald, Lukas Reisky, Jan-Hendrik Hehemann, Dörte Becher, Thomas Schweder & Uwe T. Bornscheuer
Additional file 2: Table S6. Summary of the proteomic results.

Data from: Proteomic fingerprinting enables quantitative biodiversity assessments of species and ontogenetic stages in Calanus congeners (Copepoda, Crustacea) from the Arctic Ocean

Sven Rossel, Patricia Kaiser, Maya Bode-Dalby, Jasmin Renz, Holger Auel, Wilhelm Hagen & Pedro Martínez Arbizu
Species identification is pivotal in biodiversity assessments, and proteomic fingerprinting by MALDI-TOF mass spectrometry has already been shown to reliably identify calanoid copepods to species level. However, MALDI-TOF data may contain more information beyond mere species identification. In this study, we investigated different ontogenetic stages (copepodids C1-C6 females) of three co-occurring Calanus species from the Arctic Fram Strait, which cannot be identified to species level based on morphological characters alone. Differentiation of the three species...

Nutrition Transition in Europe: East-West Dimensions in the Last 30 Years-A Narrative Review

Klara G Dokova, Rouzha Z Pancheva, Natalya V Usheva, Galina A Haralanova, Silviya P Nikolova, Todorka I Kostadinova, Caue Egea Rodrigues, Jessica Radcliffe, Anne-Kathrin Illner & Krasimira Aleksandrova
The current review aims to summarize published research on nutrition transition patterns (depicting changes in dietary consumption) in European populations over the last three decades (1990-2020), with a focus on East-West regional comparisons. Pubmed and Google-Scholar databases were searched for articles providing information on repeated dietary intakes in populations living in countries across Europe, published between January 1990 and July 2021. From the identified 18,031 articles, 62 were found eligible for review (17 from Eastern...

Weakening behavior of the shallow megasplay fault in the Nankai subduction zone

Alexander Roesner, Matt J. Ikari, Andre Hüpers & Achim J. Kopf
Abstract The Nankai Trough megasplay fault hosts diverse modes of fault slip, ranging from slow slip events to megathrust earthquakes, and is responsible for related phenomena such as tsunamis and submarine landslides. All types of slip events require some kind of frictional weakening process in order to nucleate and propagate. We tested fluid-saturated, powdered megasplay fault samples in a direct shear apparatus under effective normal stresses of 2–18 MPa to investigate their friction velocity- and...

Additional file 1 of Weakening behavior of the shallow megasplay fault in the Nankai subduction zone

Alexander Roesner, Matt J. Ikari, Andre Hüpers & Achim J. Kopf
Additional file 1: Table S1. Experimental table. All velocity step and constant velocity experiments are shown with friction dependence parameters as well as modeling parameters for the velocity step tests.

Additional file 2 of Weakening behavior of the shallow megasplay fault in the Nankai subduction zone

Alexander Roesner, Matt J. Ikari, Andre Hüpers & Achim J. Kopf
Additional file 2: Figure S1. Technical drawing of the sample holder configuration, indicating possible drainage pathways in blue.

EnMAP Science Plan

Sabine Chabrillat, Luis Guanter, Hermann Kaufmann, Saskia Foerster, Alison Beamish, Arlena Brosinsky, Hendrik Wulf, Saeid Asadzadeh, Mathias Bochow, Niklas Bohn, Nina Boesche, Astrid Bracher, Maximilian Brell, Henning Buddenbaum, D. Cerra, S. Fischer, T. Hank, U. Heiden, Birgit Heim, Wieke Heldens, J. Hill, Andre Hollstein, Patrick Hostert, Hajo Krasemann, L. LaPorta … & Karl Segl
EnMAP Technical Report;

Neighbourhood socio-economic status and positive affectivity among older residents in Germany: a cross-sectional analysis with data from the Heinz Nixdorf Recall Study

Christina Hartig, Gabriele Bolte, Karl-Heinz Jöckel, Susanne Moebus & Natalie Riedel
Abstract Background Physical and social neighbourhood characteristics can vary according to the neighbourhood socio-economic status (SES) and influence residents’ perceptions, behaviours and health outcomes both positively and negatively. Neighbourhood SES has been shown to be predictive of mental health, which is relevant for healthy ageing and prevention of dementia or depression. Positive affectivity (PA) is an established indicator of mental health and might indicate a positive emotional response to neighbourhood characteristics. In this study, we...

Hippocampal microRNA-26a-3p deficit contributes to neuroinflammation and behavioral disorders via p38 MAPK signaling pathway in rats

Changmin Wang, Ye Li, Yuhang Yi, Guiyu Liu, Ruojing Guo, Liyan Wang, Tian Lan, Wenjing Wang, Xiao Chen, Shihong Chen & Shu Yan Yu
Abstract Background Neuronal injury is considered a critical risk factor in the pathogenesis of most neurological and neuropsychiatric diseases. However, the underlying molecular mechanisms and identification of potential therapeutic targets for preventing neuronal injury associated with brain function remain largely uncharacterized. Therefore, identifying neural mechanisms would put new insights into the progression of this condition and provide novel therapeutic strategies for the treatment of these diseases. Methods Stereotactic injection of AAV virus was used to...

Strategies for implementing pet robots in care homes and nursing homes for residents with dementia: protocol for a modified Delphi study

Wei Qi Koh, Dympna Casey, Viktoria Hoel & ELAINE TOOMEY
Background: Pet robots are a type of technology-based innovation that have shown positive psychosocial benefts for people with dementia in residential facilities, such as improving mood and social interaction and reducing agitation. Nevertheless, little is known about how pet robots can be implemented in care homes and nursing homes for dementia care in real-world practice. The objectives of this study are to (1) identify contextualised implementation strategies for implementing pet robots into care homes and...

BEDMAP3 - Ice thickness, bed and surface elevation for Antarctica - standardised data points

Alice Fremand, Peter Fretwell, Julien Bodart, Hamish Pritchard, A. Aitken, Jonathan Bamber, R.E. Bell, C Bianchi, Robert Bingham, Donald Blankenship, G. Casassa, Ginny Catania, K Christianson, H Conway, Hugh Corr, X. Cui, D Damaske, V. Damn, R. Drews, G. Eagles, O. Eisen, H. Eisermann, Fausto Ferraccioli, Rene Forsberg, S Franke … & A. Zirizzotti
We present here the Bedmap3 ice thickness, bed and surface elevation standardised CSV data points that are used to create the Bedmap3 gridding products in addition to the previous data releases. The data consists of 50 million points acquired by 17 different data providers in Antarctica. The associated datasets consist of: - Bedmap1 standardised CSV data points: https://doi.org/10.5285/f64815ec-4077-4432-9f55-0ce230f46029 - Bedmap2 standardised CSV data points: https://doi.org/10.5285/2fd95199-365e-4da1-ae26-3b6d48b3e6ac - Bedmap3 statistically-summarised data points (shapefiles): https://doi.org/10.5285/a72a50c6-a829-4e12-9f9a-5a683a1acc4a This work is...

Clinical features of the first critical case of acute encephalitis caused by the avian influenza A (H5N6) virus

Libing Zhang, Kaituo Liu, Qin Su, Xiao Chen, Xiaoquan Wang, Qingfeng Li, Wenlei Wang, Xuhua Mao, Jinmei Xu, Xin Zhou, Qin Xu, Le Zhou, Xiufan Liu & Pinghu Zhang
Highly pathogenic avian influenza viruses (HPAIV), such as H5N1, H5N6, and H7N9, have been reported to frequently infect humans, but acute encephalitis caused by HPAIV in humans has been rarely reported. We report the first critical case of acute encephalitis with mild pneumonia caused by the H5N6 virus. On January 25 of 2022, a 6-year-old girl with severe neurological symptoms was admitted to our hospital and rapidly developed into seizures and coma. Brain imaging showed...

Similarities of the Scotia and Caribbean Plates: Implications for a common plate tectonic history?!

Burmeister Christian , Paul Wintersteller & Martin Meschede
The active volcanic arcs of the Scotia- and Caribbean Plate are two prominent features along the otherwise passive margins of the Atlantic Ocean, where subduction of oceanic crust is verifiable. Both arcs have been important oceanic gateways during their formation. Trapped between the large continental plates of North- and South America, as well as Antarctica, the significantly smaller oceanic plates show striking similarities in size, shape, plate margins and morphology, although formed at different times...

Volcanic structures and magmatic evolution of the Vesteris Seamount, Greenland Basin

Katharina Anna Unger Moreno, Janis Thal , Wolfgang Bach , Christoph Beier & Karsten Matthias Haase
The solitary intraplate volcano Vesteris Seamount is located in the Central Greenland Basin and rises around 3000 m above the seafloor with a total eruptive volume of ~500 km3. Newly acquired high-resolution bathymetry allows through backscatter data and raster terrain analysis to distinguish several volcanic structures. The Vesteris Seamount is a northeast to southwest elongated stellar-shaped seamount with an elongated, narrow summit radially surrounded by irregular volcanic ridges, separated by volcanic debris fans. Whole rock...

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  • 2022
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Affiliations

  • University of Bremen
    71
  • Zhejiang University
    17
  • Columbia University
    17
  • Huazhong University of Science and Technology
    17
  • China Pharmaceutical University
    17
  • Shandong University
    17
  • Guangxi University
    17
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    17
  • Shandong Agricultural University
    17
  • Wuhan University
    17