4,104 Works
Additional file 1 of mir-145-5p is a suppressor of colorectal cancer at early stage, while promotes colorectal cancer metastasis at late stage through regulating AKT signaling evoked EMT-mediated anoikis
Xianshuo Cheng, Tao Shen, Ping Liu, Shaojun Fang, Zhibin Yang, Yunfeng Li & Jian Dong
Supplementary Material 1
Additional file 1 of Phylogenomic analysis and development of molecular markers for the determination of twelve plum cultivars (Prunus, Rosaceae)
Yicen Xu, Bo Fang, Jingling Li, Yuanwei Wang, Jingting Liu, Chang Liu & Jie Yu
Additional file 1: TableS1. Summary of sequencing data quality. Table S2. Gene composition in the plastomes of twelve plum cultivars. Table S3. Length of introns and exons inthe plastomes of twelve plumcultivars. Table S4. Statistics on simple sequencerepeats (SSRs) in the twelve plastomes. TableS5. The list of accession numbers of the plastome sequences used in thephylogenetic analyses of the Prunus. FigureS1. Genome map of P. salicina ‘Wanshuang plum’ plastome. Figure S2. Genome map of P....
Additional file 1 of Phylogenomic analysis and development of molecular markers for the determination of twelve plum cultivars (Prunus, Rosaceae)
Yicen Xu, Bo Fang, Jingling Li, Yuanwei Wang, Jingting Liu, Chang Liu & Jie Yu
Additional file 1: TableS1. Summary of sequencing data quality. Table S2. Gene composition in the plastomes of twelve plum cultivars. Table S3. Length of introns and exons inthe plastomes of twelve plumcultivars. Table S4. Statistics on simple sequencerepeats (SSRs) in the twelve plastomes. TableS5. The list of accession numbers of the plastome sequences used in thephylogenetic analyses of the Prunus. FigureS1. Genome map of P. salicina ‘Wanshuang plum’ plastome. Figure S2. Genome map of P....
Additional file 3 of Age- and sex-specific reference values of biventricular strain and strain rate derived from a large cohort of healthy Chinese adults: a cardiovascular magnetic resonance feature tracking study
Gengxiao Li, Zhen Zhang, Yiyuan Gao, Chengcheng Zhu, Shanshan Zhou, Lizhen Cao, Zhiwei Zhao, Jun Zhao, Karen Ordovas, Mingwu Lou, Kuncheng Li & Gerald M. Pohost
Additional file 3: Table S1. Normal values of biventricular global strain for men and women measured by Medis. Table S2. Biventricular strain by age decades for men measured by Medis (n = 50). Table S3. Biventricular strain by age decades for women measured by Medis (n = 50). Table S4. Comparison of left ventricular global strain measured by cvi42 and Medis (n = 100). Table S5. Comparison of biventricular strain based on the two MRI...
Additional file 12 of SIGIRR deficiency contributes to CD4 T cell abnormalities by facilitating the IL1/C/EBPβ/TNF-α signaling axis in rheumatoid arthritis
Xiu Teng, Da-Chao Mou, Hui-Fang Li, Ling Jiao, Sha-Sha Wu, Jin-Kui Pi, Yan Wang, Meng-Li Zhu, Meng Tang & Yi Liu
Additional file 12: Table S5. Primer Sets for qRT‒PCR and Mouse Genotyping.
Additional file 13 of SIGIRR deficiency contributes to CD4 T cell abnormalities by facilitating the IL1/C/EBPβ/TNF-α signaling axis in rheumatoid arthritis
Xiu Teng, Da-Chao Mou, Hui-Fang Li, Ling Jiao, Sha-Sha Wu, Jin-Kui Pi, Yan Wang, Meng-Li Zhu, Meng Tang & Yi Liu
Additional file 13: Table S6. Antibodies Used for Immunoblots.
Additional file 5 of SIGIRR deficiency contributes to CD4 T cell abnormalities by facilitating the IL1/C/EBPβ/TNF-α signaling axis in rheumatoid arthritis
Xiu Teng, Da-Chao Mou, Hui-Fang Li, Ling Jiao, Sha-Sha Wu, Jin-Kui Pi, Yan Wang, Meng-Li Zhu, Meng Tang & Yi Liu
Additional file 5: Figure S5. Composition of splenic immune cells and CD4+ T cell subpopulations in healthy Sigirr +/+ mice and Sigirr −/− mice. (A), Frequencies of major immune populations in spleens between Sigirr +/+ mice (n = 5) and Sigirr −/− mice (n = 5). (B), Absolute number and frequency of granulocytes among 2.5 × 105 live CD45+ leukocytes derived from Sigirr +/+ and Sigirr −/−mice. (C), Representative plots of T cells (CD3+ NK1.1−),...
Additional file 7 of SIGIRR deficiency contributes to CD4 T cell abnormalities by facilitating the IL1/C/EBPβ/TNF-α signaling axis in rheumatoid arthritis
Xiu Teng, Da-Chao Mou, Hui-Fang Li, Ling Jiao, Sha-Sha Wu, Jin-Kui Pi, Yan Wang, Meng-Li Zhu, Meng Tang & Yi Liu
Additional file 7: Figure S7. Ectopic expression of SIGIRR in purified CD4+ T cells after transfection with retrovirus packaged by phoenix helper-free retrovirus producer lines. The expression of SIGIRR (50 kDa) and GFP (27 kDa) in CD4 T-cell lysates was detected by immunoblotting with GAPDH as a loading control.
Additional file 1 of Understanding of bacterial lignin extracellular degradation mechanisms by Pseudomonas putida KT2440 via secretomic analysis
Zhangyang Xu, Bo Peng, Reta Birhanu Kitata, Carrie D. Nicora, Karl K. Weitz, Yunqiao Pu, Tujin Shi, John R. Cort, Arthur J. Ragauskas & Bin Yang
Additional file 1: Figure S1. The overall workflow for identifying bacterial lignin degradation pathways. Figure S2. GC–MS analysis of lignin breakdown products. Figure S3. Lignin breakdown products identified by GC–MS. Figure S4. The variation of peaks area of all lignin breakdown products. Figure S5. Main detected lignin linkages. Table S1. Occurrence of putative degradation products of lignin in different treatment conditions. Table S2. Grouped lignin breakdown products among all treatments. Table S3. Main lignin 2D...
Visualizing biogeochemical heterogeneity in soils and sediments: A review of advanced micro-scale sampling and imaging methods
Cai Li, Shiming Ding, Musong Chen, Zhilin Zhong, Qin Sun & Yan Wang
For soils and sediments, which are complex and heterogeneous, root-triggered processes, bioturbation of benthic communities, and local decomposition of reactive organic materials can greatly increase their biogeochemical heterogeneity. In practice, common monitoring methods can only be used to determine the centimeter- to millimeter-scale heterogeneity from vertical or horizontal one-dimensional profiles. However, significant heterogeneity exists in both soils and sediments on the millimeter to sub-millimeter scales. Therefore, in-situ and high-resolution sampling and imaging methods are essential...
Visualizing biogeochemical heterogeneity in soils and sediments: A review of advanced micro-scale sampling and imaging methods
Cai Li, Shiming Ding, Musong Chen, Zhilin Zhong, Qin Sun & Yan Wang
For soils and sediments, which are complex and heterogeneous, root-triggered processes, bioturbation of benthic communities, and local decomposition of reactive organic materials can greatly increase their biogeochemical heterogeneity. In practice, common monitoring methods can only be used to determine the centimeter- to millimeter-scale heterogeneity from vertical or horizontal one-dimensional profiles. However, significant heterogeneity exists in both soils and sediments on the millimeter to sub-millimeter scales. Therefore, in-situ and high-resolution sampling and imaging methods are essential...
Humoral and Cellular Immunogenicity and Efficacy of a Coxsackievirus A10 Vaccine in Mice
Huan-Huan An, Meng Li, Rui-Lun Liu, Jie Wu, Sheng-Li Meng, Jing Guo, Ze-Jun Wang, Sha-Sha Qian & Shuo Shen
Coxsackievirus A10 (CV-A10) has become one of the major pathogens of hand, foot and mouth disease (HFMD), and studies on the vaccine and animal model of CV-A10 are still far from complete. Our study used a mouse adapted CV-A10 strain, which was lethal for 14-day-old mice, to develop an infected mouse model. Then this model was employed to establish an actively immunized-challenged mouse model to evaluate the efficacy of a formaldehyde-inactivated CV-A10 vaccine, which was...
Additional file 2 of B7-H3 targeted CAR-T cells show highly efficient anti-tumor function against osteosarcoma both in vitro and in vivo
Qian Zhang, Zhiqiang Zhang, Guodi Liu, Dehua Li, Zhangjie Gu, Linsong Zhang, Yingjiao Pan, Xingbing Cui, Lu Wang, Guoping Liu, Xiaoli Tian & Ziming Zhang
Additional file 2: Supplemental Figure 2. Situation of affectorcells and target cells (HOS, Saos-2, SW1353) displayed by optical microscopy.
B7-H3 targeted CAR-T cells show highly efficient anti-tumor function against osteosarcoma both in vitro and in vivo
Qian Zhang, Zhiqiang Zhang, Guodi Liu, Dehua Li, Zhangjie Gu, Linsong Zhang, Yingjiao Pan, Xingbing Cui, Lu Wang, Guoping Liu, Xiaoli Tian & Ziming Zhang
Abstract Background Osteosarcoma (OS) mainly happens in children and youths. Surgery, radiotherapy and chemotherapy are the common therapies for osteosarcoma treatment but all their anti-tumor effects are limited. In recent years, a new cellular therapy, CAR-T, a cellular immunotherapy with genetically engineered T cells bearing chimeric antigen receptor targeting specific tumor-associated antigen, has been proved to be an effective therapy against acute lymphoblastic leukemia. Thus, CAR-T is a potentially effective therapy for osteosarcoma treatment. Methods...
Additional file 12 of Costunolide is a dual inhibitor of MEK1 and AKT1/2 that overcomes osimertinib resistance in lung cancer
Xueli Tian, Rui Wang, Tingxuan Gu, Fayang Ma, Kyle Vaughn Laster, Xiang Li, Kangdong Liu, Mee-Hyun Lee & Zigang Dong
Supplementary Material 12
Additional file 4 of Costunolide is a dual inhibitor of MEK1 and AKT1/2 that overcomes osimertinib resistance in lung cancer
Xueli Tian, Rui Wang, Tingxuan Gu, Fayang Ma, Kyle Vaughn Laster, Xiang Li, Kangdong Liu, Mee-Hyun Lee & Zigang Dong
Supplementary Material 4
Additional file 6 of Costunolide is a dual inhibitor of MEK1 and AKT1/2 that overcomes osimertinib resistance in lung cancer
Xueli Tian, Rui Wang, Tingxuan Gu, Fayang Ma, Kyle Vaughn Laster, Xiang Li, Kangdong Liu, Mee-Hyun Lee & Zigang Dong
Supplementary Material 6
Additional file 8 of Costunolide is a dual inhibitor of MEK1 and AKT1/2 that overcomes osimertinib resistance in lung cancer
Xueli Tian, Rui Wang, Tingxuan Gu, Fayang Ma, Kyle Vaughn Laster, Xiang Li, Kangdong Liu, Mee-Hyun Lee & Zigang Dong
Supplementary Material 8
Development and Validation of a Clinical Prediction Model to Diagnose Sinonasal Inverted Papilloma Based on Computed Tomography Features and Clinical Characteristics
Zengxiao Zhang, Longgang Yu, Jiaxin Jiang, Lin Wang, Shizhe Zhou, Dapeng Hao & Yan Jiang
Objectives: Sinonasal inverted papilloma (SNIP) is one of the most common benign tumors of the nasal cavity and sinuses and is at risk for recurrence and malignant transformation. It is crucial to precisely predict SNIP before surgery to determine the optimal surgical technique and prevent SNIP recurrence. This study aimed to evaluate the diagnostic value of computed tomography (CT) features and SNIP clinical characteristics and to develop and validate a clinically effective nomogram. Methods: Here,...
sj-jpg-1-imr-10.1177_03000605221132704 - Supplemental material for Congenital esophageal stenosis caused by tracheobronchial remnants: a case report
Zhihong Gao, Lingyan Wang, Huaijun Liu & Xia Zhang
Supplemental material, sj-jpg-1-imr-10.1177_03000605221132704 for Congenital esophageal stenosis caused by tracheobronchial remnants: a case report by Zhihong Gao, Lingyan Wang, Huaijun Liu and Xia Zhang in Journal of International Medical Research
Congenital esophageal stenosis caused by tracheobronchial remnants: a case report
Zhihong Gao, Lingyan Wang, Huaijun Liu & Xia Zhang
We describe a case of congenital esophageal stenosis in which the patient underwent ineffective balloon dilatation twice and eventually required surgery. The case was initially misdiagnosed as achalasia. Pathological findings revealed tracheobronchial remnants (TBRs) in the muscular layer of strictured esophageal tissue. Most TBR strictures are located in the middle and lower thirds of the esophagus. Esophagography is the main examination method for esophageal stricture, and the appearance of the “rat tail sign” is a...
Congenital esophageal stenosis caused by tracheobronchial remnants: a case report
Zhihong Gao, Lingyan Wang, Huaijun Liu & Xia Zhang
We describe a case of congenital esophageal stenosis in which the patient underwent ineffective balloon dilatation twice and eventually required surgery. The case was initially misdiagnosed as achalasia. Pathological findings revealed tracheobronchial remnants (TBRs) in the muscular layer of strictured esophageal tissue. Most TBR strictures are located in the middle and lower thirds of the esophagus. Esophagography is the main examination method for esophageal stricture, and the appearance of the “rat tail sign” is a...
New onset atrial fibrillation during orthotopic liver transplantation induced by iced saline injection for transpulmonary thermodilution: a case report
Xin Li, Xu Wang & Zheng Guan
Transpulmonary thermodilution is often used to measure extravascular lung water during liver transplantation. Here, the case of new onset atrial fibrillation during orthotopic liver transplantation, which may have been induced by iced saline injection for transpulmonary thermodilution measurement, is described. A 52-year-old male patient underwent orthotopic liver transplantation due to alcoholic cirrhosis combined with portal hypertension. During dissection of the recipient liver, transpulmonary thermodilution was performed. At 3 minutes following iced saline injected, atrial fibrillation...
Additional file 4 of Pan-cancer analysis of oncogenic TNFAIP2 identifying its prognostic value and immunological function in acute myeloid leukemia
Mei-si Lin, Hui-Yun Zhong, Rita Lok-Hay Yim, Qi-Yan Chen, Hong-ling Du, Hao-qi He, Ke Lin, Peng Zhao, Ru Gao, Fei Gao & Min-Yue Zhang
Additional file 4: Supplementary Fig. S3. TNFAIP2 expression and clinical features of AML patients in the microarray data of GSE14468 from GEO database and Beat AML dataset. (a) Comparison of TNFAIP2 expression level among different subtypes of AML in the distribution of FAB classifications in the microarray data of GSE1446. (b) Comparison of TNFAIP2 expression level in AML patients according to cytogenetic risk stratification in the microarray data of GSE1446. (c-h) Comparison of TNFAIP2 expression...
Additional file 4 of Pan-cancer analysis of oncogenic TNFAIP2 identifying its prognostic value and immunological function in acute myeloid leukemia
Mei-si Lin, Hui-Yun Zhong, Rita Lok-Hay Yim, Qi-Yan Chen, Hong-ling Du, Hao-qi He, Ke Lin, Peng Zhao, Ru Gao, Fei Gao & Min-Yue Zhang
Additional file 4: Supplementary Fig. S3. TNFAIP2 expression and clinical features of AML patients in the microarray data of GSE14468 from GEO database and Beat AML dataset. (a) Comparison of TNFAIP2 expression level among different subtypes of AML in the distribution of FAB classifications in the microarray data of GSE1446. (b) Comparison of TNFAIP2 expression level in AML patients according to cytogenetic risk stratification in the microarray data of GSE1446. (c-h) Comparison of TNFAIP2 expression...
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Affiliations
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Chinese PLA General Hospital4,104
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Chinese Academy of Medical Sciences & Peking Union Medical College2,974
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Shanghai Jiao Tong University2,762
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Fudan University2,577
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Capital Medical University2,502
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Zhejiang University2,501
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Sichuan University2,384
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Sun Yat-sen University2,373
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Huazhong University of Science and Technology2,212
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Chinese Academy of Sciences2,108