13 Works

Data from: Phenotypic constraints and community structure: linking trade-offs within and among species

Amy L. Angert, Sarah Kimball, Megan Peterson, Travis E. Huxman & D. Lawrence Venable
Trade-offs are central to many topics in biology, from the evolution of life histories to ecological mechanisms of species coexistence. Trade-offs observed among species may reflect pervasive constraints on phenotypes that are achievable given biophysical and resource limitations. If so, then among-species trade-offs should be consistent with trade-offs within species. Alternatively, trait variation among co-occurring species may reflect historical contingencies during community assembly rather than within-species constraints. Here, we test whether a key trade-off between...

Data from: Pupil-linked arousal determines variability in perceptual decision making

Peter R. Murphy, Joachim Vandekerckhove & Sander Nieuwenhuis
Decision making between several alternatives is thought to involve the gradual accumulation of evidence in favor of each available choice. This process is profoundly variable even for nominally identical stimuli, yet the neuro-cognitive substrates that determine the magnitude of this variability are poorly understood. Here, we demonstrate that arousal state is a powerful determinant of variability in perceptual decision making. We measured pupil size, a highly sensitive index of arousal, while human subjects performed a...

Data from: CHOPER filters enable rare mutation detection in complex mutagenesis populations by next-generation sequencing

Faezeh Salehi, Roberta Baronio, Ryan Idrogo-Lam, Huy Vu, Linda V. Hall, Peter Kaiser, Richard Lathrop & Richard H. Lathrop
Next-generation sequencing (NGS) has revolutionized genetics and enabled the accurate identification of many genetic variants across many genomes. However, detection of biologically important low-frequency variants within genetically heterogeneous populations remains challenging, because they are difficult to distinguish from intrinsic NGS sequencing error rates. Approaches to overcome these limitations are essential to detect rare mutations in large cohorts, virus or microbial populations, mitochondria heteroplasmy, and other heterogeneous mixtures such as tumors. Modifications in library preparation can...

Data from: Extensive transcriptional response associated with seasonal plasticity of butterfly wing patterns

Emily V. Daniels, Rabi Murad, Ali Mortazavi & Robert D. Reed
In the eastern United States the buckeye butterfly, Junonia coenia, shows seasonal wing color plasticity where adults emerging in the spring are tan, while those emerging in the autumn are dark red. This variation can be artificially induced in laboratory colonies, thus making J. coenia a useful model system to examine the mechanistic basis of plasticity. To better understand the developmental basis of seasonal plasticity we used RNA-seq to quantify transcription profiles associated with development...

Data from: Fine-mapping nicotine resistance loci in Drosophila using a multiparent advanced generation inter-cross population

Tara N. Marriage, Elizabeth G. King, Anthony D. Long & Stuart J. Macdonald
Animals in nature are frequently challenged by toxic compounds, from those that occur naturally in plants as a defense against herbivory, to pesticides used to protect crops. On exposure to such xenobiotic substances, animals mount a transcriptional response, generating detoxification enzymes and transporters that metabolize and remove the toxin. Genetic variation in this response can lead to variation in the susceptibility of different genotypes to the toxic effects of a given xenobiotic. Here we use...

Data from: Opsin clines in butterflies suggest novel roles for insect photopigments

Francesca D Frentiu, Furong Yuan, Wesley K Savage, Gary D Bernard, Sean P Mullen & Adriana D Briscoe
Nucleotide Sequence Files Raw DataZip archive of the fasta files containing sequences for each individual used in clinal analyses for 3 opsin genes and wingless and EF1-alpha genes.

Data from: Complete dosage compensation and sex-biased gene expression in the moth Manduca sexta

Gilbert Smith, Yun-Ru Chen, Gary W. Bissard & Adriana D. Briscoe
Sex chromosome dosage compensation balances homogametic sex chromosome expression with autosomal expression in the heterogametic sex, leading to sex chromosome expression parity between the sexes. If compensation is incomplete this can lead to expression imbalance and sex-biased gene expression. Recent work has uncovered an intriguing and variable pattern of dosage compensation across species that includes a lack of complete dosage compensation in ZW species compared to XY species. This has led to the hypothesis that...

Data from: Patterns of selection on Plasmodium falciparum erythrocyte binding antigens after the colonisation of the New World

Erhan Yalcindag, Virginie Rougeron, Eric Elguero, Céline Arnathau, Patrick Durand, Sylvain Brisse, Laure Diancourt, Agnes Aubouy, Pierre Becquart, Umberto D'Alessandro, Didier Fontenille, Dionicia Gamboa, Amanda Maestre, Didier Ménard, Lise Musset, Oscar Noya, Vincent Veron, Albina Wide, Bernard Carme, Eric Legrand, Christine Chevillon, Francisco J. Ayala, François Renaud & Franck Prugnolle
Pathogens, which have recently colonized a new host species or new populations of the same host, are interesting models for understanding how populations may evolve in response to novel environments. During its colonization of South America from Africa Plasmodium falciparum, the main agent of malaria, has been exposed to new conditions in distinctive new human populations (Amerindian and populations of mixed origins), that likely exerted new selective pressures on the parasite's genome. Among the genes...

Data from: Using Drosophila melanogaster to identify chemotherapy toxicity genes

Elizabeth G. King, Galina Kislukhin, Kelli N. Walters & Anthony D. Long
The severity of the toxic side effects of chemotherapy shows a great deal of interindividual variability, and much of this variation is likely genetically based. Simple DNA tests predictive of toxic side effects could revolutionize the way chemotherapy is carried out. Due to the challenges in identifying polymorphisms that affect toxicity in humans, we use Drosophila fecundity following oral exposure to carboplatin, gemcitabine and mitomycin C as a model system to identify naturally occurring DNA...

Data from: Soil fertility and parasitoids shape herbivore selection on plants

Luis Abdala-Roberts, Victor Parra-Tabla, Diane R. Campbell & Kailen A. Mooney
1. Although plants and herbivores interact under varying soil resources and natural enemy effects, little is known about how these factors influence plant-herbivore interactions and shape the evolution of plant and herbivore traits. Here we ask whether soil fertility and parasitoids shape selection on fruit number imposed by a seed predator (SP) on the perennial herb Ruellia nudiflora. 2. We used a common garden where half the plants of 14 genetic families were fertilized, and...

Data from: Concentrations and ratios of particulate organic carbon, nitrogen, and phosphorus in the global ocean

Adam C. Martiny, Jasper A. Vrugt & Michael W. Lomas
Knowledge of concentrations and elemental ratios of suspended particles are important for understanding many biogeochemical processes in the ocean. These include patterns of phytoplankton nutrient limitation as well as linkages between the cycles of carbon and nitrogen or phosphorus. To further enable studies of ocean biogeochemistry, we here present a global dataset compiled from published literature and consisting of 60811 measurements of particulate organic carbon, nitrogen, and phosphorus analyzed as part of 70 cruises or...

Data from: Laboratory selection quickly erases historical differentiation

Inês Fragata, Pedro Simões, Miguel Lopes-Cunha, Margarida Lima, Bárbara Kellen, Margarida Bárbaro, Josiane Santos, Michael R. Rose, Mauro Santos & Margarida Matos
The roles of history, chance and selection have long been debated in evolutionary biology. Though uniform selection is expected to lead to convergent evolution between populations, contrasting histories and chance events might prevent them from attaining the same adaptive state, rendering evolution somewhat unpredictable. The predictability of evolution has been supported by several studies documenting repeatable adaptive radiations and convergence in both nature and laboratory. However, other studies suggest divergence among populations adapting to the...

Data from: Warning signals are seductive: relative contributions of color and pattern to predator avoidance and mate attraction in Heliconius butterflies

Susan D. Finkbeiner, Adriana D. Briscoe & Robert D. Reed
Visual signaling in animals can serve many uses, including predator deterrence and mate attraction. In many cases, signals used to advertise unprofitability to predators are also used for intraspecific communication. Although aposematism and mate choice are significant forces driving the evolution of many animal phenotypes, the interplay between relevant visual signals remains little explored. Here, we address this question in the aposematic passion-vine butterfly Heliconius erato by using color- and pattern-manipulated models to test the...

Registration Year

  • 2014

Resource Types

  • Dataset


  • University of California, Irvine
  • Cornell University
  • University of Kansas
  • University of Washington
  • University of California System
  • University of Lisbon
  • Institut Pasteur de la Guyane
  • French National Institute for Agricultural Research
  • University of Barcelona
  • Leiden University