Selective logging and forest conversion to oil palm agriculture are rapidly altering tropical forests. However, functional responses of the soil microbiome to these land-use changes are poorly understood. Using 16S rRNA gene and shotgun metagenomic sequencing, we compared composition and functional attributes of soil biota between unlogged, once-logged and twice-logged rainforest, and areas converted to oil palm plantations in Sabah, Borneo. Although there was no significant effect of logging history, we found a significant difference...
Data from: Major histocompatibility complex selection dynamics in pathogen-infected túngara frog (Physalaemus pustulosus) populationsTiffany A. Kosch, Arnaud Bataille, Chelsea Didinger, John A. Eimes, Sofia Rodríguez-Brenes, Michael J. Ryan & Bruce Waldman
Pathogen-driven selection can favour major histocompatibility complex (MHC) alleles that confer immunological resistance to specific diseases. However, strong directional selection should deplete genetic variation necessary for robust immune function in the absence of balancing selection or challenges presented by other pathogens. We examined selection dynamics at one MHC class II (MHC-II) locus across Panamanian populations of the túngara frog, Physalaemus pustulosus, infected by the amphibian chytrid fungus Batrachochytrium dendrobatidis (Bd). We compared MHC-II diversity in...
Data from: Trichobaris weevils distinguish amongst toxic host plants by sensing volatiles that do not affect larval performanceGisuk Lee, Youngsung Joo, Celia Diezel, Eun Ju Lee, Ian T. Baldwin & Sang-Gyu Kim
Herbivorous insects use plant metabolites to inform their host plant selection for oviposition. These host-selection behaviours are often consistent with the preference–performance hypothesis; females oviposit on hosts that maximize the performance of their offspring. However, the metabolites used for these oviposition choices and those responsible for differences in offspring performance remain unknown for ecologically relevant interactions. Here, we examined the host-selection behaviours of two sympatric weevils, the Datura (Trichobaris compacta) and tobacco (T. mucorea) weevils...
Data from: Using the generalized index of dissimilarity to detect gene-gene interactions in multi-class phenotypesJaeyong Yee, Yongkang Kim, Taesung Park & Mira Park
To find genetic association between complex diseases and phenotypic traits, one important procedure is conducting a joint analysis. Multifactor dimensionality reduction (MDR) is an efficient method of examining the interactions between genes in genetic association studies. It commonly assumes a dichotomous classification of the binary phenotypes. Its usual approach to determining the genomic association is to construct a confusion matrix to estimate a classification error, where a binary risk status is determined and assigned to...
Reproductive isolation is crucial for the process of speciation to progress. Sex chromosomes have been assigned a key role in driving reproductive isolation but empirical evidence from natural population processes has been restricted to organisms with degenerated sex chromosomes such as mammals and birds. Here we report restricted introgression at sex-linked compared to autosomal markers in a hybrid zone between two incipient species of European tree frog, Hyla arborea and H. orientalis, whose homologous X...
Data from: Diagnostic performance of alpha-fetoprotein, protein induced by vitamin K absence, osteopontin, Dickkopf-1 and its combinations for hepatocellular carcinomaJang Eun Sun, Jeong Sook-Hyang, Kim Jin-Wook, Choi Yun Suk, Leissner Philippe, Brechot Christian, Eun Sun Jang, Sook-Hyang Jeong, Jin-Wook Kim & Yun Suk Choi
Background & Aims: Alpha-fetoprotein (AFP) is the most widely used serum biomarker for hepatocellular carcinoma (HCC), despite its limitations. As complementary biomarkers, protein induced by vitamin K absence (PIVKA-II), osteopontin (OPN), and Dickkopf-1 (DKK-1) have been proposed. This study aimed to perform a head-to-head comparison of the diagnostic performance of AFP, PIVKA-II, OPN and DKK-1 as single or in combination to seek the best biomarker or panel, and to investigate the clinical factors affecting their...
Seoul National University6
Seoul National University Bundang Hospital1
The University of Texas at Austin1
University of Wrocław1
University of Lausanne1
Leibniz Institute of Freshwater Ecology and Inland Fisheries1
Max Planck Institute for Chemical Ecology1
University of Sao Paulo1
Institute of Vertebrate Biology1