109 Works

Using a socioecologial approach to explore the integration of exercise physiologists into primary healthcare teams in Newfoundland and Labrador, Canada

Limited research has explored the integration of Clinical Exercise Physiologists (CEPs) into primary healthcare in Canada. As part of a clinical exercise referral program at Memorial University, graduate students recognized as CEPs participated in four month placements at local family medicine clinics. This thesis aims to explore the experiences of CEPs and physicians during the integration of CEPs into healthcare teams and identify challenges and opportunities that could impact broader implementation of this referral program....

Pedagogical studies in virtual offshore safety training

To better prepare the offshore workforce for emergencies, operators and regulators need to use evidence-based safety training. This research aims to provide such evidence by employing an experimental program to evaluate virtual environment (VE) training as a plausible means to enhance mandatory offshore egress training. Combining VE technology with a well-designed, pedagogically informed training program, and carefully selected data-mining tools, can support the development of trainee competence in emergencies by providing artificial experience in credible...

Indemnification and the building of Canadian pipelines

The Canadian Federal Government’s purchase of the Trans Mountain pipeline in 2018 was seen by many as a singular action to support the pipeline industry. However, this research will contend that this is not the case because this thesis will show that the federal government has indemnified the oil and gas pipeline industry in Canada over the past 60 years. This will be shown by focusing on three large-scale positive examples of Federal Government indemnification,...

Time-lapse seismic imaging and uncertainty quantification

Time–lapse (4D) seismic monitoring is to date the most commonly used technique for estimating changes of a reservoir under production. Full–Waveform Inversion (FWI) is a high resolution technique that delivers Earth models by iteratively trying to match synthetic prestack seismic data with the observed data. Over the past decade the application of FWI on 4D data has been extensively studied, with a variety of strategies being currently available. However, 4D FWI still has challenges unsolved....

Analysis of Ptp10D and Ptp4E during ageing and in Parkinson Disease models in Drosophila melanogaster

Parkinson Disease (PD) is an age-dependent neurological disease that diminishes locomotory abilities. PD is the second most common neurodegenerative disease, after Alzheimer Disease (AD), with a lifetime risk of approximately one in 40 in human. The symptoms of PD include resting tremors, rigidity, and bradykinesia and are caused by a loss of dopaminergic neurons in the substantia nigra of the midbrain. Based upon a recent study, a group of novel candidate genes was discovered with...

Long- and short-term solutions for mitigating hazardous noise exposure and noise levels on board vessels from the small-scale fishing fleet of Newfoundland and Labrador

Fish harvesting in Newfoundland and Labrador (NL) is prominently a small-scale industry. This is an important activity in the rural NL, providing a mean of livelihood and identity to many coastal communities. Fishing is also one of the most dangerous professions both in the province and worldwide, with high incidence of reported casualties, accidents, and injuries. Among many health and safety issues of the fish harvesting profession, elevated noise levels pose a subtle threat. Prolonged...

Climate change impacts on berry shrub performance in treeline and tundra ecosystems

Climate variability and warming are directly, indirectly and irrefutably driving widespread changes in global aquatic and terrestrial ecosystems, with disproportionate poleward impacts. Across Arctic treeline and tundra, understanding how current and future changes will negatively affect subsistence resources is critical to mitigating climate change impacts on Indigenous peoples and northern flora and fauna. In this study, I looked to Inuit knowledge and western scientific approaches at local and regional scales across Inuit Nunangat (Inuit regions...

Community participation in sustainable tourism development in Rose Blanche, Newfoundland and Labrador

This research focuses on the community participation in sustainable tourism development in Rose Blanche, Newfoundland and Labrador, Canada. Rose Blanche is one of the six remaining small towns on Newfoundland and Labrador province’s Southwest shore. The traditional occupation of the local communities of Rose Blanche was fishing. When the fishing industry collapsed in Rose Blanche in 1990, and the town faced economic restructuring, it became clear that the ability of Rose Blanche to grow and...

Development of multi-MHz Class-D soft-switching inverters

Wireless Power Transmission (WPT) systems are becoming rapidly mature and accessible to customers, and it is expected that they are going to take a large share of the electrical equipment market around the world in the near future. Many tech companies and university research labs have recently focused on design, development, and optimization of different blocks of these systems. WPT systems can be designed to transfer power either through electric fields or magnetic fields. Operating...

Improved solubility, dissolution rate, and oral bioavailability of main biflavonoids from Selaginella doederleinii extract by amorphous solid dispersion

Bing Chen, Xuewen Wang, Yanyan Zhang, Kangping Huang, Hao Liu, Dafen Xu, Shaoguang Li, Qicai Liu, Jianyong Huang, Hong Yao & Xinhua Lin
Amentoflavone, robustaflavone, 2″,3″-dihydro-3′,3‴-biapigenin, 3′,3‴-binaringenin, and delicaflavone are five major hydrophobic components in the total biflavonoids extract from Selaginella doederleinii (TBESD) that display favorable anticancer properties. The purpose of this study was to develop a new oral delivery formulation to improve the solubilities, dissolution rates, and oral bioavailabilities of the main ingredients in TBESD by the solid dispersion technique. Solid dispersions of TBESD with various hydrophilic polymers were prepared, and different technologies were applied to select...

Singing behaviour of Ruby-crowned Kinglets (Regulus calendula) in relation to time-of-day, time-of-year, and social context

Mohammad Fahmy & David Wilson
Observational field studies provide insight on the multifunctional nature of birdsong. For example, if song production were limited to pre-fertilization, then that would suggest a mate attraction function. If it were used throughout the breeding season and in response to intruding males, then that would suggest a territorial defence function. In the present study, we determined the daily and seasonal singing patterns of male Ruby-crowned Kinglets (Regulus calendula) in Labrador, Canada, using microphone arrays in...

Fabrication of doxorubicin-gated mesoporous polydopamine nanoplatforms for multimode imaging-guided synergistic chemophotothermal therapy of tumors

Min Yang, Ningnan Zhang, Tao Zhang, Xian Yin & Jie Shen
A versatile theranostic agent that integrated with therapeutic and diagnostic functions is extremely essential for cancer theranostic. Herein, a multifunctional theranostic nanoplatform (PFP@MPDA-DOX) based on perfluoropentane (PFP) encapsulated mesoporous polydopamine (MPDA) is elaborately designed, followed by gating of drug doxorubicin (DOX) for preventing cargo leaking. The MPDA with pH-responsive biodegradation behavior was served as nanocarrier, which also endows the nanoplatform with a large cavity for PFP filling. The nanoparticles were then gated with DOX molecule...

Data from: Modelling the potential efficacy of treatments for white-nose syndrome in bats

Quinn Fletcher, Quinn Webber & Craig Willis
1. The fungal disease white-nose syndrome (WNS) has caused mass mortality in some species of North American bats during hibernation. 2. We use population viability models to test if a hypothetical WNS treatment or management action could facilitate the recovery of WNS-affected little brown myotis (Myotis lucifugus) populations. We modelled scenarios altering three parameters: (1) WNS severity (population growth rate of WNS-affected populations; λWNS); (2) proportion of population treated; and (3) treatment improvement in winter...

Data from: Divergent estimates of herd-wide caribou calf survival: ecological factors and methodological biases

Edward Hance Ellington, Keith P. Lewis, Erin Koen & Eric Vander Wal
Population monitoring is a critical part of effective wildlife management, but methods are prone to biases that can hinder our ability to accurately track changes in populations through time. Calf survival plays an important role in ungulate population dynamics and can be monitored using telemetry and herd composition surveys. These methods, however, are susceptible to unrepresentative sampling and violations of the assumption of equal detectability, respectively. Here we capitalized on 55 herd-wide estimates of woodland...

Open source SCADA systems for small renewable power generation.

Low cost monitoring and control is essential for small renewable power systems. While large renewable power systems can use existing commercial technology for monitoring and control, that is not cost-effective for small renewable generation. Such small assets require cost-effective, flexible, secure, and reliable real-time coordinated data monitoring and control systems. Supervisory control and data acquisition (SCADA) is the perfect technology for this task. The available commercial SCADA solutions are mostly pricey and economically unjustifiable for...

The formation of Muslim identities in Canadian offline and online spaces.

Understanding information diversity in the era of repurposable crowdsourced data

Organizations successfully leverage information technology for the acquisition of knowledge for decision-making through information crowdsourcing, which is gathering information from a group of people about a phenomenon of interest to the crowdsourcer. Information crowdsourcing has been used to drive business insight and scientific research, providing crowdsourcers access to information outside their traditional reach. Crowdsourcers seek high-quality data for their information crowdsourcing projects and require contributors who can provide data that meet predetermined requirements. Crowdsourcers recruit...

A mixed methods investigation of non-medical prescription stimulant use to promote wakefulness at an Atlantic Canadian university

This study is a mixed-methods investigation into the non-medical use of prescription stimulants for the purpose of staying awake among students at Memorial University of Newfoundland. The quantitative part of the study involved a comprehensive online survey, which asked for information regarding demographic characteristics and substance use, and included standardized measures of sleep, mental health and attitudes towards non-medical use of prescription drugs. A total of 3,699 participants were recruited and the clean, complete data...

Joint analysis of a quantile of longitudinal outcomes and multiple time to events with censoring

It is very common in health science studies that we observe both longitudinal and survival data, within which different types of data are correlated and need to be analysed together to draw accurate conclusions. In this thesis, we propose a new method to jointly analyse observations of a longitudinal outcome and occurring times for multiple right- and interval-censored events to capture the underlying effects between them. In order to have a more complete view, we...

Temporal and spatial changes in benthic mollusc (bivalves and gastropods) communities in inner Frobisher Bay, Nunavut, Baffin Island over fifty years

Benthic fauna are a crucial part of the marine ecosystem providing many ecosystem services. Unfortunately, Arctic coastal marine environments are under tremendous pressure from changing climate conditions and it is becoming increasingly important to understand community changes occurring in these environments. Long-term ecological studies in the Canadian Arctic are rare, however, Frobisher Bay provides a unique opportunity to study long-term change in the marine benthos because historical benthic community datasets exist for this region. We...

Sea ice remote sensing using spaceborne global navigation satellite system reflectometry

In this research, the application of spaceborne Global Navigation Satellite System- Reflectometry (GNSS-R) delay-Doppler maps (DDMs) for sea ice remote sensing is investigated. Firstly, a scheme is presented for detecting sea ice from TechDemoSat-1 (TDS-1) DDMs. Less spreading along delay and Doppler axes is observed in the DDMs of sea ice relative to those of seawater. This enables us to distinguish sea ice from seawater through studying the values of various DDM observables, which describe...

A randomized controlled trial comparing right lateral decubitus and left lateral decubitus starting position on outcomes in colonoscopy

Patient positioning in colonoscopy has been proposed as a simple and inexpensive technique to increase luminal distention and improve navigation through the large bowel. We sought to determine if right lateral (RL) starting position compared to the standard left lateral (LL) starting position could improve outcomes in colonoscopy. Patients presenting for their scheduled colonoscopy were consented for the trial and randomized to RL or LL starting position. Variables including age, sex, BMI, time to cecal...

Scattering from stratified media with a rough surface: application to sea ice ridges

Sea ice ridging is the dominant factor contributing to sea ice thickness, which has impacts on climate change and transportation. It is important to know the age of sea ice ridges, since ice age affects the strength of the ice and its ability to persist through the summer melt season. However, information on the age of sea ice ridges is not commonly available. The goal of this thesis is to develop a method to distinguish...

The development and evaluation of the cardiovascular assessment screening program

BACKGROUND: An exploratory mixed methods study, with the philosophical basis of pragmatism and interpretive description, was used to develop, implement, and evaluate an intervention called the Cardiovascular Assessment Screening Program (CASP) to address the underutilization of clinical practice guidelines for cardiovascular screening. The Knowledge-to-Action (KTA) Framework with guideline adaptation was used to guide the study. METHODS: In phase 1, the qualitative study, ten interviews and five focus groups were conducted with healthcare providers (HCPs), managers,...

Characterization of Vps13 in Drosophila melanogaster

Parkinson Disease (PD), the most common movement disorder, is a neurodegenerative disease that affects about 1% of the human population over the age of 65 years, and its prevalence increases with age. PD is clinically characterized by resting tremor, rigidity and bradykinesia as a result of the loss of dopaminergic neurons in the substantia nigra pars compacta in the mid-brain. Mitochondria play a significant role in PD. The PD candidate gene VPS13C was identified in...

Registration Year

  • 2020

Resource Types

  • Text
  • Dataset


  • Memorial University of Newfoundland
  • Sichuan University
  • Fudan University
  • Zhejiang University
  • Hong Kong Baptist University
  • Chengdu Medical College
  • University of Guelph
  • Zhongnan Hospital of Wuhan University
  • Southern Medical University
  • Shanghai Jiao Tong University