126 Works

Evaluation of an enclosed air-lift photobioreactor (ALPBR) for biomass and lipid biosynthesis of microalgal cells grown under fluid-induced shear stress

Ning Ding, Chao Li, Tao Wang, Meijin Guo, Ali Mohsin & Siliang Zhang
An enclosed air-lift photobioreactor (ALPBR) is considered an efficient lab-scale bioreactor for microalgae cell growth and lipid biosynthesis. However, fluid-induced shear stress and mixing are two main factors that affect physiological metabolism in microalgal cell cultures. Herein, a 50-L ALPBR after being designed and manufactured was evaluated for microalgal suspension culture. Moreover, computational fluid dynamics (CFD) simulation was used to characterize the hydrodynamics of ALPBR. Specifically, two model microalgae species Chlorella vulgaris and Chlorella protothecoides...

Effect of preoperative CT angiography examination on the clinical outcome of patients with BMI ≥ 25.0 kg/m2 undergoing laparoscopic gastrectomy: study protocol for a multicentre randomized controlled trial

Cheng Meng, Shougen Cao, Xiaodong Liu, Leping Li, Qingsi He, Lijian Xia, Lixin Jiang, Xianqun Chu, Xinjian Wang, Hao Wang, Xizeng Hui, Zuocheng Sun, Shusheng Huang, Quanhong Duan, Daogui Yang, Huanhu Zhang, Yulong Tian, Zequn Li & Yanbing Zhou
Abstract Background Gastric cancer, which is the fifth most common malignancy and the third most common cause of cancer-related death, is particularly predominant in East Asian countries, such as China, Japan and Korea. It is a serious global health issue that causes a heavy financial burden for the government and family. To our knowledge, there are few reports of multicentre randomized controlled trials on the utilization of CT angiography (CTA) for patients who are histologically...

Effect of preoperative CT angiography examination on the clinical outcome of patients with BMI ≥ 25.0 kg/m2 undergoing laparoscopic gastrectomy: study protocol for a multicentre randomized controlled trial

Cheng Meng, Shougen Cao, Xiaodong Liu, Leping Li, Qingsi He, Lijian Xia, Lixin Jiang, Xianqun Chu, Xinjian Wang, Hao Wang, Xizeng Hui, Zuocheng Sun, Shusheng Huang, Quanhong Duan, Daogui Yang, Huanhu Zhang, Yulong Tian, Zequn Li & Yanbing Zhou
Abstract Background Gastric cancer, which is the fifth most common malignancy and the third most common cause of cancer-related death, is particularly predominant in East Asian countries, such as China, Japan and Korea. It is a serious global health issue that causes a heavy financial burden for the government and family. To our knowledge, there are few reports of multicentre randomized controlled trials on the utilization of CT angiography (CTA) for patients who are histologically...

Additional file 1 of Effect of preoperative CT angiography examination on the clinical outcome of patients with BMI ≥ 25.0 kg/m2 undergoing laparoscopic gastrectomy: study protocol for a multicentre randomized controlled trial

Cheng Meng, Shougen Cao, Xiaodong Liu, Leping Li, Qingsi He, Lijian Xia, Lixin Jiang, Xianqun Chu, Xinjian Wang, Hao Wang, Xizeng Hui, Zuocheng Sun, Shusheng Huang, Quanhong Duan, Daogui Yang, Huanhu Zhang, Yulong Tian, Zequn Li & Yanbing Zhou
Additional file 1. Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) 2013 checklist.

Plant–insect interactions from the mid-Cretaceous at Puy-Puy (Aquitaine Basin, western France) indicates preferential herbivory for angiosperms amid a forest of ferns, gymnosperms, and angiosperms

Artai A. Santos, Lifang Xiao, Conrad C. Labandeira, Didier Néraudeau, Éric Dépré, Jean-David Moreau, Vincent Perrichot & Torsten Wappler
Plants and insects are the two dominant groups in terrestrial ecosystems, and insect damage on fossil plants is the only direct evidence documenting the past ecological history between these two, hyperdiverse groups. We describe, analyze, and interpret plant–insect interactions of a lower Cenomanian paleoforest from western France – the Puy-Puy Quarry of the Nouvelle-Aquitaine Region. We examined 1605 fossil leaves, axes, and reproductive material of bennettitalean, pinalean, and ginkgoalean gymnosperms; lauralean and magnolialean angiosperms; and...

MOF-derived multi-interface carbon-based composites with enhanced polarization loss and efficient microwave absorption

Hongjiao Qu, Peng Zheng, Tao Wang, Xingyu Yu, Junjie Pan, Xiaoli Fan, Tengfei Zhang, Xin Sun & Jianping He
Metal-organic framework materials (MOFs) have been widely studied because of their adjustable composition and controllable structure in the field of microwave absorption (MA). Therein, Prussian blue analogs (PBA) have attracted the attention of researchers with ultra-high metal content. However, the attenuation ability of microwave for PBA-based composites is still unsatisfactory up to now. Therefore, the NiFe/CoFe@C composites were prepared by carbonizing polymetallic PBA (NiCoFe PBA) materials in this work, and the influence of different metal...

Additional file 1 of Psychometric validation of a chinese version of COVID-19 vaccine hesitancy scale: a cross-sectional study

Yiman Huang, Yijin Wu, Zhenwei Dai, Weijun Xiao, Hao Wang, Mingyu Si, Wenjun Wang, Xiaofen Gu, Li Ma, Li Li, Shaokai Zhang, Chunxia Yang, Yanqin Yu, Youlin Qiao & Xiaoyou Su
Additional file 1: COVID-19 Vaccine Hesitancy Scale Item Description.

Additional file 1 of Risk factors and outcomes of postoperative stroke in surgical treatment for giant intracranial aneurysms

Hao Wang, Junlin Lu, Xin Chen & Qiang Hao
Additional file 1: Table Supplementary. Logistic regression analysis for postoperative strokes in clipping sub-group.

Supplemental Material - Theoretical, numerical, and experimental studies on controlled synchronization strategy of four-axis variable trajectory equal-thickness screen

Sai Li, Chusheng Liu, Gao Chen, Hao Wang, Hongxi Li & Deyi He
Supplemental Material for Theoretical, numerical, and experimental studies on controlled synchronization strategy of four-axis variable trajectory equal-thickness screen by Sai Li, Chusheng Liu, Gao Chen, Hao Wang, Hongxi Li and Deyi He in Journal of Vibration and Control.

Theoretical, numerical, and experimental studies on controlled synchronization strategy of four-axis variable trajectory equal-thickness screen

Sai Li, Chusheng Liu, Gao Chen, Hao Wang, Hongxi Li & Deyi He
The four-axis variable trajectory equal-thickness screen (FAVTETS) achieves equal-thickness screening by appropriate excitation force generated by four eccentric rotors in synchronized motion. The forced synchronization exciter is characterized by an unsatisfactory synchronization effect due to the wear of transmission parts. Hence, in this paper, the four-axis controlled synchronization of FAVTETS is investigated, and an intelligent control system is proposed. Firstly, research is conducted on the variable trajectory characteristics of FAVTETS. Next, the sliding mode, fuzzy,...

Additional file 7 of Aberrant methylation of Serpine1 mediates lung injury in neonatal mice prenatally exposed to intrauterine inflammation

Dongting Yao, Jiuru Zhao, Qianqian Zhang, Tao Wang, Meng Ni, Sudong Qi, Qianwen Shen, Wei Li, Baihe Li, Xiya Ding & Zhiwei Liu
Additional file 7: Figure S7. Schematic representation of the molecular mechanisms underlying IUI-induced lung injury in neonatal mice.

Additional file 1 of Mitochondrial genomic analyses provide new insights into the “missing” atp8 and adaptive evolution of Mytilidae

Baojun Zhao, Shengtao Gao, Mingyang Zhao, Hongyu Lv, Jingyu Song, Hao Wang, Qifan Zeng & Jing Liu
Additional file 1: TableS1. Branch-site model analyses in deep sea branches

Additional file 1 of Mining and characterization of the PKS–NRPS hybrid for epicoccamide A: a mannosylated tetramate derivative from Epicoccum sp. CPCC 400996

Tao Zhang, Guowei Cai, Xiaoting Rong, Jingwen Xu, Bingya Jiang, Hao Wang, Xinxin Li, Lu Wang, Ran Zhang, Wenni He & Liyan Yu
Additional file 1: Table S1. NMR Data for epicoccamide A (1). Table S2. Comparison of the signature residues for amino acid selection by adenylation (A) domains of fungal PKS-NRPS (NRPS). Figure S1. The 1H NMR spectrum of compound 1. Figure S2. The 13C NMR spectrum of compound 1. Figure S3. The 1H-1H COSY spectrum of compound 1 (in DMSO). Figure S4. The HSQC spectrum of compound 1 (in DMSO). Figure S5. The HMBC spectrum of...

Recombinant human thrombopoietin (rhTPO) of different dosing regimens for refractory/relapsed primary immune thrombocytopenia: a multicenter, randomized controlled trial and pharmacokinetics study

Xiaofan Liu, Yusheng Bai, Tao Wang, Yanping Song, Feng Sun, Ruixiang Xia, Feiyue Zhu, Jun Ma, Quanyi Lu, Xu Ye, Xinrong Zhan, Linjie Li, Xinhong Guo, Shuqin Cheng, Yan Li, Zhiqiang Guo, Youhua Chen, Shenxian Qian, Ling Qin, Qing Zhang, Sunqiong Cao & Renchi Yang
Recombinant human TPO (rhTPO) is effective for refractory/relapsed primary immune thrombocytopenia (ITP), but optimal dosing regimen remains elusive. In this multicenter, randomized, controlled trial, a total of 282 adult ITP patients (mean age 47.3 years; 82 men) with a platelet count ≤30 × 109/L or >30 × 109/L with active bleeding randomly received a once daily (QD) subcutaneous injection of 7500 U (n = 64) or 15000 U rhTPO for 14 injections, or 15000 U...

Supplementary document for Polarizer-free measurement of the full Stokes vector using a fiber-coupled superconducting nanowire single photon detector with a polarization extinction ratio of ~2 - 6160463.pdf

Yue Fei, Tianhao Ji, Guanghao Zhu, Labao Zhang, Lijian Zhang, jingrou tan, qi chen, Yanqiu Guan, Rui Yin & Hao Wang
Supplemental document of theory model and experimental details

Polarizer-free measurement of the full Stokes vector using a fiber-coupled superconducting nanowire single photon detector with a polarization extinction ratio of ~2

Yue Fei, Tianhao Ji, Guanghao Zhu, Labao Zhang, Lijian Zhang, jingrou tan, qi chen, Yanqiu Guan, Rui Yin & Hao Wang
The characterization and manipulation of the polarization states at single photon level are of great importance in research fields such as quantum information processing and quantum key distribution, where the photons are normally delivered using single mode optical fibers. To date, the demonstrated polarimetry measurement techniques based on a superconducting nanowire single photon detector (SNSPD) require the SNSPD to be either highly sensitive or highly insensitive to the photon’s polarization state, therefore placing an unavoidable...

RNA-binding Protein LIN28a Regulates New Myocyte Formation in the Heart via lncRNA-H19

Vagner Oliveira-Carvalho Rigaud, Robert C. Hoy, Justin Kurian, Clare Zarka, Michael Behanan, Isabella Brosious, Jennifer Pennise, Tej M. Patel, Tao Wang, Jaslyn Johnson, Lindsay Kraus, Sadia Mohsin, Steven R. Houser & Mohsin Khan
Background: Developmental cardiac tissue holds remarkable capacity to regenerate after injury and consists of regenerative mononuclear and diploid cardiomyocytes (MNDCMs). Upon maturation, MNDCMs become binucleated or polyploid and exit the cell cycle. Interestingly, cardiomyocyte (CM) metabolism undergoes a profound shift that coincides with cessation of regeneration in the postnatal heart. However, whether reprogramming metabolism promotes persistence of regenerative MNDCMs enhancing cardiac function and repair after injury is unknown. Here, we identify a novel role for...

RNA-binding Protein LIN28a Regulates New Myocyte Formation in the Heart via lncRNA-H19

Vagner Oliveira-Carvalho Rigaud, Robert C. Hoy, Justin Kurian, Clare Zarka, Michael Behanan, Isabella Brosious, Jennifer Pennise, Tej M. Patel, Tao Wang, Jaslyn Johnson, Lindsay Kraus, Sadia Mohsin, Steven R. Houser & Mohsin Khan
Background: Developmental cardiac tissue holds remarkable capacity to regenerate after injury and consists of regenerative mononuclear and diploid cardiomyocytes (MNDCMs). Upon maturation, MNDCMs become binucleated or polyploid and exit the cell cycle. Interestingly, cardiomyocyte (CM) metabolism undergoes a profound shift that coincides with cessation of regeneration in the postnatal heart. However, whether reprogramming metabolism promotes persistence of regenerative MNDCMs enhancing cardiac function and repair after injury is unknown. Here, we identify a novel role for...

Macrophage-derived exosomes accelerate wound healing through their anti-inflammation effects in a diabetic rat model

Mengdie Li, Tao Wang, He Tian, Guohua Wei, Liang Zhao & Yijie Shi
Chronic, subclinical inflammation was often observed in the diabetic wound area, causing inadequate and delayed wound-healing effects by failing to initiate cell migration, proliferation, and extracellular matrix deposition. Therefore, we presented macrophage-derived exosomes (Exos) and explored their potential for inhibiting inflammation and accelerating diabetic wound healing in a skin defect, diabetic rat model. A thorough investigation demonstrated that Exos exerted anti-inflammatory effects by inhibiting the secretion of pro-inflammatory enzymes and cytokines. Furthermore, they accelerated the...

Evaluation of an enclosed air-lift photobioreactor (ALPBR) for biomass and lipid biosynthesis of microalgal cells grown under fluid-induced shear stress

Ning Ding, Chao Li, Tao Wang, Meijin Guo, Ali Mohsin & Siliang Zhang
An enclosed air-lift photobioreactor (ALPBR) is considered an efficient lab-scale bioreactor for microalgae cell growth and lipid biosynthesis. However, fluid-induced shear stress and mixing are two main factors that affect physiological metabolism in microalgal cell cultures. Herein, a 50-L ALPBR after being designed and manufactured was evaluated for microalgal suspension culture. Moreover, computational fluid dynamics (CFD) simulation was used to characterize the hydrodynamics of ALPBR. Specifically, two model microalgae species Chlorella vulgaris and Chlorella protothecoides...

E74 Like ETS Transcription Factor 3 is a Negative Regulator of Pathogenic Lamina Propria T Helper 17.1 Cells in Murine Colitis

Bo Hu, Hao Wang & Fei Xiao
Interleukin-17A (IL-17A)-expressing T cells, including T helper 17 (Th17) and T helper 17.1 (Th17.1) cells, play a significant role in inflammatory bowel diseases (IBDs). Identifying the mechanisms underlying the heterogeneity and plasticity of IL-17A-expressing T cells is crucial for understanding and controlling their pathogenicity. The role of E74 like ETS transcription factor 3 (ELF3) in regulating the pathogenicity of IL-17A-expressing T cells has not been studied before. Dextran sulfate sodium was used to induce acute...

MOF-derived multi-interface carbon-based composites with enhanced polarization loss and efficient microwave absorption

Hongjiao Qu, Peng Zheng, Tao Wang, Xingyu Yu, Junjie Pan, Xiaoli Fan, Tengfei Zhang, Xin Sun & Jianping He
Metal-organic framework materials (MOFs) have been widely studied because of their adjustable composition and controllable structure in the field of microwave absorption (MA). Therein, Prussian blue analogs (PBA) have attracted the attention of researchers with ultra-high metal content. However, the attenuation ability of microwave for PBA-based composites is still unsatisfactory up to now. Therefore, the NiFe/CoFe@C composites were prepared by carbonizing polymetallic PBA (NiCoFe PBA) materials in this work, and the influence of different metal...

Psychometric validation of a chinese version of COVID-19 vaccine hesitancy scale: a cross-sectional study

Yiman Huang, Yijin Wu, Zhenwei Dai, Weijun Xiao, Hao Wang, Mingyu Si, Wenjun Wang, Xiaofen Gu, Li Ma, Li Li, Shaokai Zhang, Chunxia Yang, Yanqin Yu, Youlin Qiao & Xiaoyou Su
Abstract Background COVID-19 vaccines have been administered in many countries; however, a sufficient vaccine coverage rate is not guaranteed due to vaccine hesitancy. To improve the uptake rate of COVID-19 vaccine, it is essential to evaluate the rate of vaccine hesitancy and explore relevant factors in different populations. An urgent need is to measure COVID-19 vaccine hesitancy among different population groups, hence a validated scale for measuring COVID-19 vaccine hesitancy is necessary. The present study...

Study on Physicochemical Properties and Potential Applications of Chemically Treated Luffa Sponge Fibers

Beibei Weng, Dao Cheng, Fangcheng Yuan, Xinzhou Wang, Fuli Wang, Hao Wang, Qingyang Zhang, Kaiting Zhang, Shanshan Wu, Yuhong Gao, Jiachen Wang, Yan Lv, Zicheng Wu, Yingquan Tan, Yong Guo & Yuxia Chen
To explore and expand the application of luffa sponge (LS) fiber, three methods were used to chemically modify the LS fibers. The nanoindentation (NI) results show that the LS fibers exhibit a high elastic modulus (12.4 GPa) and hardness (0.7 GPa). Upon treating the fibers with 5%NaOH-5%H2O2, the NI hardness of the fibers increases by 14.3%. However, when 10%NaOH-20%CH3COOH (method B) is used, the hardness of the cell walls decreases by 28.6%. In this case,...

Identification of HMGB2 associated with proliferation, invasion and prognosis in lung adenocarcinoma via weighted gene co-expression network analysis

Xie Qiu, Wei Liu, Yifan Zheng, Kai Zeng, Hao Wang, Haijun Sun & Jianhua Dai
Abstract Background High mobility group protein B2 (HMGB2) is a multifunctional protein that plays various roles in different cellular compartments. Moreover, HMGB2 serves as a potential prognostic biomarker and therapeutic target for lung adenocarcinoma (LUAD). Methods In this study, the expression pattern, prognostic implication, and potential role of HMGB2 in LUAD were evaluated using the integrated bioinformatics analyses based on public available mRNA expression profiles from The Cancer Genome Atlas and Gene Expression Omnibus databases,...

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