2 Works

Data from: In vivo dynamics of skeletal muscle Dystrophin in zebrafish embryos revealed by improved FRAP analysis

Fernanda Bajanca, Vinicio Gonzalez-Perez, Sean J. Gillespie, Cyriaque Beley, Luis Garcia, Eric Theveneau, Richard P. Sear & Simon M. Hughes
Dystrophin forms an essential link between sarcolemma and cytoskeleton, perturbation of which causes muscular dystrophy. We analysed Dystrophin binding dynamics in vivo for the first time. Within maturing fibres of host zebrafish embryos, our analysis reveals a pool of diffusible Dystrophin and complexes bound at the fibre membrane. Combining modelling, an improved FRAP methodology and direct semi-quantitative analysis of bleaching suggests the existence of two membrane-bound Dystrophin populations with widely differing bound lifetimes: a stable,...

Data from: New insights into carbon acquisition and exchanges within the coral-dinoflagellate symbiosis under NH4+ and NO3- supply

Leïla Ezzat, Jean-François Maguer, Renaud Grover & Christine Ferrier-Pagès
Anthropogenic nutrient enrichment affects the biogeochemical cycles and nutrient stoichiometry of coastal ecosystems and is often associated with coral reef decline. However, the mechanisms by which dissolved inorganic nutrients, and especially nitrogen forms (ammonium versus nitrate) can disturb the association between corals and their symbiotic algae are subject to controversial debate. Here, we investigated the coral response to varying N : P ratios, with nitrate or ammonium as a nitrogen source. We showed significant differences...

Registration Year

  • 2015

Resource Types

  • Dataset


  • Scientific Centre of Monaco
  • University of Surrey
  • Centre de Biologie du Développement
  • King's College London
  • Inserm