5 Works

Data from: Epigenetic response to environmental change: DNA methylation varies with invasion status

Aaron W. Schrey, Travis R. Robbins, Jacob Lee, David W. Dukes, Alexandria K. Ragsdale, Christopher J. Thawley & Tracy Langkilde
Epigenetic mechanisms may be important for a native species’ response to rapid environmental change. Red Imported Fire Ants (Solenopsis invicta Santschi, 1916) were recently introduced to areas occupied by the Eastern Fence Lizard (Sceloporus undulatus Bosc & Daudin, 1801). Behavioral, morphological, and physiological phenotypes of the Eastern Fence Lizard have changed following invasion, creating a natural biological system to investigate environmentally induced epigenetic changes. We tested for variation in DNA methylation patterns in Eastern Fence...

Data from: Malaria transmission potential could be reduced with current and future climate change

Courtney C. Murdock, Eleanore D. Sternberg & Matthew B. Thomas
Several studies suggest the potential for climate change to increase malaria incidence in cooler, marginal transmission environments. However, the effect of increasing temperature in warmer regions where conditions currently support endemic transmission has received less attention. We investigate how increases in temperature from optimal conditions (27 °C to 30 °C and 33 °C) interact with realistic diurnal temperature ranges (DTR: ± 0 °C, 3 °C, and 4.5 °C) to affect the ability of key vector...

Data from: Fitness consequences of altered feeding behavior in immune-challenged mosquitoes

Johanna R. Ohm, Janet Teeple, William A. Nelson, Matthew B. Thomas, Andrew F. Read & Lauren J. Cator
Background: Malaria-infected mosquitoes have been reported to be more likely to take a blood meal when parasites are infectious than when non-infectious. This change in feeding behavior increases the likelihood of malaria transmission, and has been considered an example of parasite manipulation of host behavior. However, immune challenge with heat-killed Escherichia coli induces the same behavior, suggesting that altered feeding behavior may be driven by adaptive responses of hosts to cope with an immune response,...

Data from: Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice

Clarissa C. Parker, Shyam Gopalakrishnan, Peter Carbonetto, Natalia M. Gonzales, Emily Leung, Yeonhee J. Park, Emmanuel Aryee, Joe Davis, David A. Blizard, Cheryl L. Ackert-Bicknell, Arimantas Lionikas, Jonathan K. Pritchard & Abraham A. Palmer
Although mice are the most widely used mammalian model organism, genetic studies have suffered from limited mapping resolution due to extensive linkage disequilibrium (LD) that is characteristic of crosses among inbred strains. Carworth Farms White (CFW) mice are a commercially available outbred mouse population that exhibit rapid LD decay in comparison to other available mouse populations. We performed a genome-wide association study (GWAS) of behavioral, physiological and gene expression phenotypes using 1,200 male CFW mice....

Data from: Archaeogenomic evidence reveals prehistoric matrilineal dynasty

Douglas J. Kennett, Stephen Plog, Richard J. George, Brendan J. Culleton, Adam S. Watson, Pontus Skoglund, Nadin Rohland, Swapan Mallick, Kristin Stewardson, Logan Kistler, Steven A. LeBlanc, Peter M. Whiteley, David Reich & George H. Perry
For societies with writing systems, hereditary leadership is documented as one of the hallmarks of early political complexity and governance. In contrast, it is unknown whether hereditary succession played a role in the early formation of prehistoric complex societies that lacked writing. Here we use an archaeogenomic approach to identify an elite matriline that persisted between 800 and 1130 CE in Chaco Canyon, the centre of an expansive prehistoric complex society in the Southwestern United...

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