96 Works

Additional file 1 of RTX-KG2: a system for building a semantically standardized knowledge graph for translational biomedicine

E. C. Wood, Amy K. Glen, Lindsey G. Kvarfordt, Finn Womack, Liliana Acevedo, Timothy S. Yoon, Chunyu Ma, Veronica Flores, Meghamala Sinha, Yodsawalai Chodpathumwan, Arash Termehchy, Jared C. Roach, Luis Mendoza, Andrew S. Hoffman, Eric W. Deutsch, David Koslicki & Stephen A. Ramsey
Additional file 1: Table S1. Ontologies from the OBO Foundry that are included in RTX-KG2

Characterizing the inherent activity of urinary bladder matrix for adhesion, migration, and activation of fibroblasts as compared with collagen-based synthetic scaffold

Xiaoyu Tang, Fengbo Yang, Guoping Chu, Xiaoxiao Li, Qiuyan Fu, Mingli Zou, Peng Zhao & Guozhong Lu
The mechanism of action underlying the intriguing prominent bioactivity of urinary bladder matrix (UBM) for in situ tissue regeneration of soft tissue defects remains to be elucidated. It is speculated that the activity of UBM for cell adhesion, migration, and activation is inherent. The bioactivity of UBM for in situ tissue regeneration and its relation with the structure and intact soluble components of UBM were investigated in comparison to a collagen-based scaffold, PELNAC (PEL). We...

Characterizing the inherent activity of urinary bladder matrix for adhesion, migration, and activation of fibroblasts as compared with collagen-based synthetic scaffold

Xiaoyu Tang, Fengbo Yang, Guoping Chu, Xiaoxiao Li, Qiuyan Fu, Mingli Zou, Peng Zhao & Guozhong Lu
The mechanism of action underlying the intriguing prominent bioactivity of urinary bladder matrix (UBM) for in situ tissue regeneration of soft tissue defects remains to be elucidated. It is speculated that the activity of UBM for cell adhesion, migration, and activation is inherent. The bioactivity of UBM for in situ tissue regeneration and its relation with the structure and intact soluble components of UBM were investigated in comparison to a collagen-based scaffold, PELNAC (PEL). We...

Supplemental Material - Psychometrics of the Physical Resilience Scale in Older Adults Living with Dementia: Proxy Responses

Barbara Resnick, Marie Boltz, Elizabeth Galik, Ashley Kuzmik, Jeanette Ellis & Chris Wells
Supplemental Material for Psychometrics of the Physical Resilience Scale in Older Adults Living with Dementia: Proxy Responses by Barbara Resnick, PhD, CRNP, Marie Boltz, PhD, CRNP, Elizabeth Galik, PhD, Ashley Kuzmik, PhD, Jeanette Ellis, MA, and Chris Wells, PT, PhD, CCS, ATC, FCCM in Journal of Aging and Health.

Supplemental Material - Psychometrics of the Physical Resilience Scale in Older Adults Living with Dementia: Proxy Responses

Barbara Resnick, Marie Boltz, Elizabeth Galik, Ashley Kuzmik, Jeanette Ellis & Chris Wells
Supplemental Material for Psychometrics of the Physical Resilience Scale in Older Adults Living with Dementia: Proxy Responses by Barbara Resnick, PhD, CRNP, Marie Boltz, PhD, CRNP, Elizabeth Galik, PhD, Ashley Kuzmik, PhD, Jeanette Ellis, MA, and Chris Wells, PT, PhD, CCS, ATC, FCCM in Journal of Aging and Health.

Psychometrics of the Physical Resilience Scale in Older Adults Living with Dementia: Proxy Responses

Barbara Resnick, Marie Boltz, Elizabeth Galik, Ashley Kuzmik, Jeanette Ellis & Chris Wells
Objectives: The purpose of this study was to determine if proxies can complete the Physical Resilience Scale for older adults living with dementia. Methods: This was a descriptive study using Rasch analysis and baseline data from the Function Focused Care for Acute Care Using the Evidence Integration Triangle trial. The first 240 patients living with dementia were included in this analysis. Results: There was evidence of reliability based on person and item separation index. There...

Additional file 1 of Pharmacological mechanism and therapeutic efficacy of Icariside II in the treatment of acute ischemic stroke: a systematic review and network pharmacological analysis

Xu Wang, Jinjian Li, Lifang Liu, Jun-Ming Kan, Ping Niu, Zi-Qiao Yu, Chunyu Ma, Fuxiang Dong, Mo-Xuan Han, Jinhua Li & De-xi Zhao
Additional file 1: Supplementary file 1. PRISMA Checklist.

Additional file 3 of Pharmacological mechanism and therapeutic efficacy of Icariside II in the treatment of acute ischemic stroke: a systematic review and network pharmacological analysis

Xu Wang, Jinjian Li, Lifang Liu, Jun-Ming Kan, Ping Niu, Zi-Qiao Yu, Chunyu Ma, Fuxiang Dong, Mo-Xuan Han, Jinhua Li & De-xi Zhao
Additional file 3. Quality assessment of CAMARADES and ARRIVE.

Additional file 3 of Pharmacological mechanism and therapeutic efficacy of Icariside II in the treatment of acute ischemic stroke: a systematic review and network pharmacological analysis

Xu Wang, Jinjian Li, Lifang Liu, Jun-Ming Kan, Ping Niu, Zi-Qiao Yu, Chunyu Ma, Fuxiang Dong, Mo-Xuan Han, Jinhua Li & De-xi Zhao
Additional file 3. Quality assessment of CAMARADES and ARRIVE.

Additional file 4 of Pharmacological mechanism and therapeutic efficacy of Icariside II in the treatment of acute ischemic stroke: a systematic review and network pharmacological analysis

Xu Wang, Jinjian Li, Lifang Liu, Jun-Ming Kan, Ping Niu, Zi-Qiao Yu, Chunyu Ma, Fuxiang Dong, Mo-Xuan Han, Jinhua Li & De-xi Zhao
Additional file 4. Information of AIS and ICS II targets.

Dataset: Canonical approach to cation flux calibration in oxide molecular-beam epitaxy

Jiaxin Sun, Christopher Parzyck, June Lee, Charles Brooks, Lena Kourkoutis, Xianglin Ke, Rajiv Misra, Jürgen Schubert, Felix Hensling, Zhe Wang, Zhe Wang , Megan Holtz, Nathaniel Schreiber, Qi Song, Hanjong Paik, Tassilo Heeg, David Muller, Kyle Shen & Darrell Schlom

Electrodynamic Levitation Diffusion Chamber Measurements of the Mass Growth of Ice Crystals Grown from the Vapor at -65 to -40C

G. Pokrifka, A. Myle & J.Y. Harrington
This data set comprises individual time-series for ice crystals grown in an electrodynamic levitation diffusion chamber at temperatures between -65 and -40C. Descriptions of the chamber and experimental proceedure can be found in Harrison et al. (2016), Pokrifka et al. (2020), and Pokrifka et al. (submitted to J. Atmos. Sci. 2022). Experiments were conducted by freezing small (approximately 10 micrometer radius) droplets either homogeneously or heterogeneously with a 0.2 g/L Snomax mixture. Frozen droplets were...

Supplementary data, code, and information for ‘Interhemispheric antiphasing of neotropical precipitation during the past millennium’ (PNAS, Steinman et al. 2022)

B.A. Steinman, N. Stansall, M.E. Mann, C.A. Cooke, M.B. Abbott, M. Vuille, B.W. Bird, M.S. Lachniet & A. Fernandez
Uncertainty about the influence of anthropogenic radiative forcing on the position and strength of convective rainfall in the Intertropical Convergence Zone (ITCZ) inhibits our ability to project future tropical hydroclimate change in a warmer world. Paleoclimatic and modeling data inform on the timescales and mechanisms of ITCZ variability; yet a comprehensive, long-term perspective remains elusive. Here, we quantify the evolution of neotropical hydroclimate over the pre-industrial past millennium (850 to 1850 CE) using a synthesis...

Shale Network – Groundwater Analyses from Beaver, Washington, and Greene Counties (Pennsylvania) as of 6/2022

S.W. Shaheen, T. Wen, A. Herman & S. Brantley
Abstract This data set is a subset of the Shale Network database (https://doi.org/10.4211/his-data-shalenetwork) and has been discussed in the following publication “Shaheen, S., Wen, T., Herman, A., Brantley, S., 2022. Geochemical evidence of groundwater contamination and potential human health risks where hydraulic fracturing overlaps with extensive legacy hydrocarbon extraction. Environmental Science & Technology”. The Shale Network (http://www.shalenetwork.org/) is a project funded by the National Science Foundation to help scientists and citizens store data for water...

Telomere length correlates with physiological and behavioural responses of a long-lived seabird to an ecologically-relevant challenge

Z Morgan Benowitz-Fredericks, Lindsay Lacey, Shannon Whelan, Alexis Will, Scott Hatch & Alexander Kitaysky
Determinants of individual variation in reallocation of limited resources towards self-maintenance versus reproduction are not well known. We tested the hypothesis that individual heterogeneity in long-term “somatic state” a) explains variation in endocrine and behavioural responses to environmental challenges, and b) is associated with variation in strategies for allocating to self-maintenance versus reproduction. We used relative telomere length as an indicator of somatic state and experimentally generated an abrupt short-term reduction of food availability (withdrawal...

Geographic and temporal morphological stasis in the latest Cretaceous ammonoid Discoscaphites iris from the U.S. Gulf and Atlantic Coastal Plains

James Witts, Corinne Myers, Matthew Garb, Kayla Irizarry, Ekaterina Larina, Anastasia Rashkova & Neil Landman
We examine temporal and spatial variation in morphology of the ammonoid cephalopod Discoscaphites iris using a large dataset from multiple localities in the Late Cretaceous (Maastrichtian) of the United States Gulf and Atlantic Coastal Plains, spanning a distance of 2000 km along the paleoshoreline. Our results suggest that the fossil record of D. iris is consistent with no within species net accumulation of phyletic evolutionary change across morphological traits or the lifetime of this species....

Coarse-Grained Models for Local Density Gradients

M.R. DeLyser & W.G. Noid
Coarse-grained (CG) models provide superior computational efficiency for simulating soft materials. Unfortunately, CG models with conventional pair-additive potentials demonstrate limited transferability between bulk and interfacial environments. Recently, a growing number of CG models have supplemented these pair potentials with one-body potentials of the local density (LD) around each site. These LD potentials can significantly improve the accuracy and transferability of CG models. Nevertheless, it remains challenging to accurately describe interfaces where the LD varies rapidly....

Population genetic and geographic data of six Neotropical plant species

Diana Gamba & Nathan Muchhala
We examined population genetic structure and fine-scale spatial genetic structure (FSGS) in six perennial understory angiosperms in Andean cloud forests of northwestern Ecuador. Species belong to three families (Gesneriaceae, Melastomataceae, and Rubiaceae), and within each family we paired one insect-pollinated with one hummingbird-pollinated species, predicting that insect-pollinated species have greater population differentiation (as quantified with the FST statistic) and stronger FSGS (as quantified with the SP statistic) than hummingbird-pollinated species.

Caution is warranted when using animal space-use and movement to infer behavioral states

Frances E. Buderman, Tess M. Gingery, Duane R. Diefenbach, Laura C. Gigliotti, Danielle Begley-Miller, Marc M. McDill, Bret D. Wallingford, Christopher S. Rosenberry & Patrick J. Drohan
Background: Identifying the behavioral state for wild animals that can’t be directly observed is of growing interest to the ecological community. Advances in telemetry technology and statistical methodologies allow researchers to use space-use and movement metrics to infer the underlying, latent, behavioral state of an animal without direct observations. For example, researchers studying ungulate ecology have started using these methods to quantify behaviors related to mating strategies. However, little work has been done to determine...

Supplementary data, code, and information for ‘Testing the Fidelity of Methods Used in Proxy-based Reconstructions of Past Climate’ (Journal of Climate, Mann et al. 2005)

M. Mann, S. Rutherford, E. Wahl & C. Ammann
Two widely used statistical approaches to reconstructing past climate histories from climate “proxy” data such as tree rings, corals, and ice cores are investigated using synthetic “pseudoproxy” data derived from a simulation of forced climate changes over the past 1200 yr. These experiments suggest that both statistical approaches should yield reliable reconstructions of the true climate history within estimated uncertainties, given estimates of the signal and noise attributes of actual proxy data networks.

Low water availability enhances volatile-mediated direct defenses but disturbs indirect defenses against herbivores

Po-An Lin, Sulav Paudel, Nursyafiqi Bin Zainuddin, Ching-Wen Tan, Anjel Helms, Jared Ali & Gary Felton
1. Interactions between plants and natural enemies of insect herbivores influence plant productivity and survival by reducing herbivory. Plants attract natural enemies via herbivore-induced plant volatiles (HIPVs), but how water availability (WA) influences HIPV-mediated defenses is unclear. 2. We use tomato (Solanum lycopersicum), tomato fruitworm (Helicoverpa zea), and two natural enemies, the parasitoid wasp (Microplitis croceipes) and the predator spined soldier bug (Podisus maculiventris), to investigate the effect of WA on HIPV emission dynamics and...

Additional file 1 of RTX-KG2: a system for building a semantically standardized knowledge graph for translational biomedicine

E. C. Wood, Amy K. Glen, Lindsey G. Kvarfordt, Finn Womack, Liliana Acevedo, Timothy S. Yoon, Chunyu Ma, Veronica Flores, Meghamala Sinha, Yodsawalai Chodpathumwan, Arash Termehchy, Jared C. Roach, Luis Mendoza, Andrew S. Hoffman, Eric W. Deutsch, David Koslicki & Stephen A. Ramsey
Additional file 1: Table S1. Ontologies from the OBO Foundry that are included in RTX-KG2

RTX-KG2: a system for building a semantically standardized knowledge graph for translational biomedicine

E. C. Wood, Amy K. Glen, Lindsey G. Kvarfordt, Finn Womack, Liliana Acevedo, Timothy S. Yoon, Chunyu Ma, Veronica Flores, Meghamala Sinha, Yodsawalai Chodpathumwan, Arash Termehchy, Jared C. Roach, Luis Mendoza, Andrew S. Hoffman, Eric W. Deutsch, David Koslicki & Stephen A. Ramsey
Abstract Background Biomedical translational science is increasingly using computational reasoning on repositories of structured knowledge (such as UMLS, SemMedDB, ChEMBL, Reactome, DrugBank, and SMPDB in order to facilitate discovery of new therapeutic targets and modalities. The NCATS Biomedical Data Translator project is working to federate autonomous reasoning agents and knowledge providers within a distributed system for answering translational questions. Within that project and the broader field, there is a need for a framework that can...

A snapshot of the entire Shale Network database as of June 2022

T. Wen & S. Brantley
This data set is a snapshot copy of the entire Shale Network database (https://doi.org/10.4211/his-data-shalenetwork) as of June 17, 2022. The Shale Network (http://www.shalenetwork.org/) is a project funded by the National Science Foundation to help scientists and other stakeholders store data for water resources that may be affected by gas exploitation in shale in the U.S.A. Our primary focus currently is the northeastern U.S.A. We want to enable the generation of knowledge from water chemistry and...

Becoming Desirably Strange: A Dialogue Between Aaron Knochel and Roger Malina

Aaron Knochel & Roger Malina
A dialogue that developed over several months between guest editor Aaron Knochel and Leonardo Executive Editor Roger Malina regarding the special collection Vibrant Ecologies of Research. The writing started as a transcript from a live conversation which was then extended and annotated asynchronously.

Registration Year

  • 2022
    96

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    71
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    11
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    8
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    5
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    1

Affiliations

  • Pennsylvania State University
    96
  • Nantong University
    14
  • Jilin University
    10
  • Temple University
    10
  • Fudan University Shanghai Cancer Center
    10
  • Wenzhou Medical University
    10
  • Sichuan University
    10
  • Fudan University
    10
  • Chongqing Medical University
    10
  • Shanghai Jiao Tong University
    10