142 Works

The effects of Trichoderma atroviride pretreatment on the biogas production from anaerobic digestion of water hyacinth

Obianuju Patience Ilo, S’phumelele Lucky Nkomo, Ntandoyenkosi Malusi Mkhize, Onisimo Mutanga & Mulala Danny Simatele
Water hyacinth is an invasive alien plant with several impacts on the environment, economy and society. The plant’s high degree of proliferation makes its mitigation difficult and sometimes complex. However, existing evidence suggests that water hyacinth is a sustainable substrate for biogas production. Using the pretreatment processes for the optimisation conditions for biogas production from water hyacinth, this study analysed the effects of moisture content (60%, 70% and 75%) on Trichoderma atroviride pretreatment of water...

The effects of Trichoderma atroviride pretreatment on the biogas production from anaerobic digestion of water hyacinth

Obianuju Patience Ilo, S’phumelele Lucky Nkomo, Ntandoyenkosi Malusi Mkhize, Onisimo Mutanga & Mulala Danny Simatele
Water hyacinth is an invasive alien plant with several impacts on the environment, economy and society. The plant’s high degree of proliferation makes its mitigation difficult and sometimes complex. However, existing evidence suggests that water hyacinth is a sustainable substrate for biogas production. Using the pretreatment processes for the optimisation conditions for biogas production from water hyacinth, this study analysed the effects of moisture content (60%, 70% and 75%) on Trichoderma atroviride pretreatment of water...

Injectable enzyme-catalyzed crosslinking hydrogels as BMSCs-laden tunable scaffold for osteogenic differentiation

Hongwei Pan, Wanxin Li, Yue Qu, Simei Li, Ayixiemu Yusufu, Jia Wang & Lihua Yin
Bone defects caused by trauma or tumor are a significant challenge in clinical practice. Hydrogel-based tissue engineering has been considered an effective strategy. This study successfully formed a series of injectable hydrogels by enzyme-catalyzed crosslinking hyaluronic acid-tyramine (HA-TA) and sodium alginate-tyramine (ALG-TA) under physiological conditions in the presence of both horseradish peroxidase and hydrogen peroxide. The morphology, mechanical properties, swelling properties, and biodegradation properties of hydrogels were investigated. The results showed that the mechanical properties,...

Injectable enzyme-catalyzed crosslinking hydrogels as BMSCs-laden tunable scaffold for osteogenic differentiation

Hongwei Pan, Wanxin Li, Yue Qu, Simei Li, Ayixiemu Yusufu, Jia Wang & Lihua Yin
Bone defects caused by trauma or tumor are a significant challenge in clinical practice. Hydrogel-based tissue engineering has been considered an effective strategy. This study successfully formed a series of injectable hydrogels by enzyme-catalyzed crosslinking hyaluronic acid-tyramine (HA-TA) and sodium alginate-tyramine (ALG-TA) under physiological conditions in the presence of both horseradish peroxidase and hydrogen peroxide. The morphology, mechanical properties, swelling properties, and biodegradation properties of hydrogels were investigated. The results showed that the mechanical properties,...

Alleviative effects of foraging exercise on depressive-like behaviors in chronic mild stress-induced ischemic rat model

Xi Tao, Siyuan Wu, Wenjing Tang, Lu Li, Lijun Huang, Danheng Mo, Chujuan Liu, Tao Song, Shuling Wang, Jia Wang & Juan He
Poststroke depression (PSD) is a common complication that seriously affects the functional recovery and prognosis of an individual. As some patients with PSD fail to respond to drug therapy, it is urgent to find a viable alternative treatment. An active exercise program known as foraging exercise (FE), using food as bait, was designed. First, focal ischemia and chronic unpredictable mild stress (CUMS) were used to establish a PSD model in rats. FE was then performed...

Ethical and practical considerations arising from community consultation on implementing controlled human infection studies using Schistosoma mansoni in Uganda

Moses Egesa, Agnes Ssali, Edward Tumwesige, Moses Kizza, Emmanuella Driciru, Fiona Luboga, Meta Roestenberg, Janet Seeley & Alison M. Elliott
Issues related to controlled human infection studies using Schistosoma mansoni (CHI-S) were explored to ensure the ethical and voluntary participation of potential CHI-S volunteers in an endemic setting in Uganda. We invited volunteers from a fishing community and a tertiary education community to guide the development of informed consent procedures. Consultative group discussions were held to modify educational materials on schistosomiasis, vaccines and the CHI-S model and similar discussions were held with a test group....

Ethical and practical considerations arising from community consultation on implementing controlled human infection studies using Schistosoma mansoni in Uganda

Moses Egesa, Agnes Ssali, Edward Tumwesige, Moses Kizza, Emmanuella Driciru, Fiona Luboga, Meta Roestenberg, Janet Seeley & Alison M. Elliott
Issues related to controlled human infection studies using Schistosoma mansoni (CHI-S) were explored to ensure the ethical and voluntary participation of potential CHI-S volunteers in an endemic setting in Uganda. We invited volunteers from a fishing community and a tertiary education community to guide the development of informed consent procedures. Consultative group discussions were held to modify educational materials on schistosomiasis, vaccines and the CHI-S model and similar discussions were held with a test group....

The use of multisource spatial data for determining the proliferation of stingless bees in Kenya

David Masereti Makori, Elfatih M. Abdel-Rahman, Nelly Ndungu, John Odindi, Onisimo Mutanga, Tobias Landmann, Henri E. Z. Tonnang & Nkoba Kiatoko
Stingless/meliponine bees are eusocial insects whose polylactic nature enables interaction with a wide variety of wild plants and crops that enhance pollination and, hence, support ecosystem services. However, their true potential regarding pollination services and honey production is yet to be fully recognized. Worldwide, there are over 800 species of meliponine bees, with over 20 species documented on the African continent. Out of these, only 12 species have been well documented in Kenya. Moreover, interest...

South African communal indigenous goats

Tlou Caswell Chokoe, Khanyisile Hadebe, Farai Muchadeyi, Edgar Dzomba, Khathutshelo Nephawe, Tumudi Mphahlele, Tlou Matelele & Bohani Mtileni
Indigenous goats form the majority of populations in smallholder; low input, low output production systems and are considered an important genetic resource due to their adaptability to different production environments and support communal farming. Effective population size (Ne), inbreeding levels, and the runs of homozygosity (ROHs) are effective tools for exploring the genetic diversity and understanding the demographic history in efforts to support breeding strategies to use and conserve genetic resources. Across populations, the current...

Additional file 1 of Barriers and facilitators to HIV prevention interventions for reducing risky sexual behavior among youth worldwide: a systematic review

Fungai Mbengo, Esther Adama, Amanda Towell-Barnard, Arvin Bhana & Maggie Zgambo
Additional file 1. Table S1. Search strategy in MEDLINE. Table S2. Critical appraisal results of included quasi-experimental studies (quantitative studies). Table S3. Critical appraisal results of included randomized controlled trial (quantitative study). Table S4. Critical appraisal results of included qualitative studies and mixed methods study (qualitative component).

Additional file 2 of Barriers and facilitators to HIV prevention interventions for reducing risky sexual behavior among youth worldwide: a systematic review

Fungai Mbengo, Esther Adama, Amanda Towell-Barnard, Arvin Bhana & Maggie Zgambo
Additional file 2. Additional tables.

Additional file 1 of A healthcare workers’ mHealth adoption instrument for the developing world

Michael Addotey-Delove, Richard E. Scott & Maurice Mars
Additional file 1.

Additional file 1 of A healthcare workers’ mHealth adoption instrument for the developing world

Michael Addotey-Delove, Richard E. Scott & Maurice Mars
Additional file 1.

A healthcare workers’ mHealth adoption instrument for the developing world

Michael Addotey-Delove, Richard E. Scott & Maurice Mars
Abstract Introduction Healthcare workers’ adoption of mHealth is critical to the success or failure of clinician based mHealth services in the developing world. mHealth adoption is affected or promoted by certain factors, some of which are peculiar to the developing world. Identifying these factors and evaluating them will help develop a valid and reliable measuring instrument for more successful prediction of mHealth adoption in the future. The aim of this study was to design and...

Vecchia-Approximated Deep Gaussian Processes for Computer Experiments

Annie Sauer, Andrew Cooper & Robert B. Gramacy
Deep Gaussian processes (DGPs) upgrade ordinary GPs through functional composition, in which intermediate GP layers warp the original inputs, providing flexibility to model nonstationary dynamics. Two DGP regimes have emerged in recent literature. A “big data” regime, prevalent in machine learning, favors approximate, optimization-based inference for fast, high-fidelity prediction. A “small data” regime, preferred for computer surrogate modeling, deploys posterior integration for enhanced uncertainty quantification (UQ). We aim to bridge this gap by expanding the...

Linking migration and microbiota at a major stopover site in a long-distance avian migrant

Nikki Thie, Ammon Corl, Sondra Turjeman, Ron Efrat, Pauline L. Kamath, Wayne M. Getz, Rauri C. K. Bowie & Ran Nathan
Abstract Migration is one of the most physical and energetically demanding periods in an individual bird’s life. The composition of the bird’s gut or cloacal microbiota can temporarily change during migration, likely due to differences in diets, habitats and other environmental conditions experienced en route. However, how physiological condition, migratory patterns, and other drivers interact to affect microbiota composition of migratory birds is still unclear. We sampled the cloacal bacterial microbiota of a long-distance migrant,...

Additional file 1 of Patient journey and resources mapping to implement a praziquantel mass drug administration program for children aged 5 years and below in resource-limited settings

Mhlengi Vella Ncube, Muhubiri Kabuyaya & Moses John Chimbari
Additional file 1. Preferred Reporting Itemsfor Systematic reviews and Meta-Analyses extension for Scoping Reviews(PRISMA-ScR) Checklist.

Additional file 1 of ‘If I am playing football, I forget that I have this virus’: the challenges and coping strategies of adolescents with perinatally acquired HIV in KwaZulu-Natal, South Africa

Marian Loveday, Jennifer Furin, Sindisiwe Hlangu, Thabile Mthethwa & Tasneem Naidoo
Additional file 1. Detailed study methodology.

‘If I am playing football, I forget that I have this virus’: the challenges and coping strategies of adolescents with perinatally acquired HIV in KwaZulu-Natal, South Africa

Marian Loveday, Jennifer Furin, Sindisiwe Hlangu, Thabile Mthethwa & Tasneem Naidoo
Abstract Background Adolescents who have acquired HIV perinatally (ALHIV) face unique challenges in taking lifelong antiretroviral therapy (ART), but little is known about what factors affect their adherence over the course of their lifelong treatment journey. Methods We conducted a qualitative study with ALHIV who had periods of poor adherence to ART in KwaZulu-Natal, South Africa using Participant-generated Visual Methodologies (PVM). Participants used photography to represent their perspectives and experiences. Results 14 individuals participated in...

Additional file 1 of Shared component modelling of early childhood anaemia and malaria in Kenya, Malawi, Tanzania and Uganda

Danielle J. Roberts & Temesgen Zewotir
Additional file 1.

Shared component modelling of early childhood anaemia and malaria in Kenya, Malawi, Tanzania and Uganda

Danielle J. Roberts & Temesgen Zewotir
Abstract Background Malaria and anaemia contribute substantially to child morbidity and mortality. In this study, we sought to jointly model the residual spatial variation in the likelihood of these two correlated diseases, while controlling for individual-level, household-level and environmental characteristics. Methods A child-level shared component model was utilised to partition shared and disease-specific district-level spatial effects. Results The results indicated that the spatial variation in the likelihood of malaria was more prominent compared to that...

Additional file 2 of Association between water, sanitation and hygiene (WASH) and child undernutrition in Ethiopia: a hierarchical approach

Biniyam Sahiledengle, Pammla Petrucka, Abera Kumie, Lillian Mwanri, Girma Beressa, Daniel Atlaw, Yohannes Tekalegn, Demisu Zenbaba, Fikreab Desta & Kingsley Emwinyore Agho
Supplementary Material 2

Additional file 1 of Communication Skills (CS) training of physicians in China and its role in actual challenges of patient-physician relationship: a cross-sectional survey

Junfeng Du, Gwendolyn Mayer, Elisabetta Posenato, Svenja Hummel, Ali Zafar, Till Bärnighausen & Jobst-Hendrik Schultz
Additional file 1: Appendix I. Communication Skills Questionnaire.

Additional file 2 of Communication Skills (CS) training of physicians in China and its role in actual challenges of patient-physician relationship: a cross-sectional survey

Junfeng Du, Gwendolyn Mayer, Elisabetta Posenato, Svenja Hummel, Ali Zafar, Till Bärnighausen & Jobst-Hendrik Schultz
Additional file 2: Appendix II. Results of the Communication Skills Attitudes Scale: Items, direction of scale, means, standard deviations, and 95% confidence intervals (N = 772).

Communication Skills (CS) training of physicians in China and its role in actual challenges of patient-physician relationship: a cross-sectional survey

Junfeng Du, Gwendolyn Mayer, Elisabetta Posenato, Svenja Hummel, Ali Zafar, Till Bärnighausen & Jobst-Hendrik Schultz
Abstract Background The Chinese healthcare system is affected by frequent disputes between physicians and patients. Although recent reforms have contributed towards improving the patient-physician relationship, distrust in physicians is still high. Communication skills (CS) training of physicians holds the key to improving patient confidence and diffusing stressful situations. This survey reports on the status of CS training in medical education in China, and the experiences and attitudes of physicians towards CS training. Methods A cross-sectional...

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Affiliations

  • University of KwaZulu-Natal
    142
  • Jiangsu Academy of Agricultural Sciences
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  • Jilin University
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  • Inner Mongolia Agricultural University
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  • Southwest University
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  • Oak Ridge National Laboratory
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  • Second Hospital of Shanxi Medical University
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