140 Works

Data from: Individual variation, population-specific behaviours, and stochastic processes shape marine migration phenologies

Cameron Freshwater, Marc Trudel, Terry D. Beacham, Stéphane Gauthier, Stewart C. Johnson, Chrys-Ellen Neville & Francis Juanes
1. The phenology of long distance migrations can influence individual fitness, moderate population dynamics, and regulate the availability of ecosystem services to other trophic levels. Phenology varies within and among populations, and can be influenced by conditions individuals experience both prior to departure and encounter en route. 2. Assessing how intrinsic and extrinsic factors (e.g. individual physical condition vs. environmental conditions) interact to influence variation in migratory phenologies across ecological scales is often limited due...

Data from: Estimating density for species conservation: comparing camera trap spatial count models to genetic spatial capture-recapture models

Joanna M. Burgar, Frances E. C. Stewart, John P. Volpe, Jason T. Fisher, A. Cole Burton & Frances E.C. Stewart
Density estimation is integral to the effective conservation and management of wildlife. Camera traps in conjunction with spatial capture-recapture (SCR) models have been used to accurately and precisely estimate densities of “marked” wildlife populations comprising identifiable individuals. The emergence of spatial count (SC) models holds promise for cost-effective density estimation of “unmarked” wildlife populations when individuals are not identifiable. We evaluated model agreement, precision, and survey costs, between i) a fully marked approach using SCR...

Divergence in life history and behaviour between hybridizing Phymata

David Punzalan
Life history variation plays a central role in evolutionary and ecological processes, and may be especially pertinent to divergence in closely related species. We investigated life history differences in a pair of parapatric species of ambush bugs (Phymata) and a putative hybrid population. Despite the evidence of gene flow among these species, we found clear divergence between these parapatric populations for a suite of juvenile and adult life history traits including components of fitness. The...

Data from: Understory succession after burial by tephra from Mount St. Helens

Dylan G. Fischer, Joseph A. Antos, Abir Biswas & Donald B. Zobel
1. Successional change following disturbance is a fundamental ecological process that remains central to understanding patterns in plant ecology. Although succession has been studied for well over a century, understanding of the patterns and processes of change is still inadequate, partly because of the dearth of long-term studies. 2. Here, we use, as a model system, a volcanic disturbance that is widespread and of global relevance. We examine succession in old-growth conifer forest understories following...

Tropicalization of temperate reef fish communities facilitated by urchin grazing and diversity of thermal affinities

Jasmin Schuster, Rick Stuart-Smith, Graham Edgar & Amanda Bates
Aim: Global declines in structurally complex habitats are reshaping both land and seascapes in directions that affect biological communities’ responses to warming. Here, we test whether widespread loss of kelp habitats through sea urchin overgrazing systematically changes sensitivity of fish communities to warming. Location: Global temperate latitudes Time period: Modern Major taxa studied: Fishes Methods: Community thermal affinity shifts related to habitat were assessed by simulating and comparing fish communities from 2,271 surveys across 15...

Hybrid evolution repeats itself across environmental contexts in Texas sunflowers (Helianthus)

Nora Mitchell, Hoang Luu, Gregory Owens, Loren Rieseberg & Kenneth Whitney
To what extent is evolution repeatable? Little is known about whether the evolution of hybrids is more (or less) repeatable than non-hybrids. We used field experimental evolution in annual sunflowers (Helianthus) in Texas to ask the extent to which hybrid evolution is repeatable across environments compared to non-hybrid controls. We created hybrids between Helianthus annuus (L.) and H. debilis (Nutt.) and grew plots of both hybrids and non-hybrid controls through eight generations at three sites...

The genomic consistency of the loss of anadromy in an Arctic fish (Salvelinus alpinus)

Sarah Salisbury, Gregory McCracken, Robert Perry, Donald Keefe, Kara Layton, Tony Kess, Cameron Nugent, Jong Leong, Ian Bradbury, Ben Koop, Moira Ferguson & Daniel Ruzzante
The potentially significant genetic consequences associated with the loss of migratory capacity of diadromous fishes which have become landlocked in freshwater are poorly understood. Consistent selective pressures associated with freshwater residency may drive repeated differentiation both between allopatric landlocked and anadromous populations and within landlocked populations (resulting in sympatric morphs). Alternatively, the strong genetic drift anticipated in isolated landlocked populations could hinder consistent adaptation, limiting genetic parallelism. Understanding the degree of genetic parallelism underlying differentiation...

Life stage and taxonomy the most important factors determining vertebrate stoichiometry: A meta-analysis

Emily May & Rana El Sabaawi
1. Whole-body elemental composition is a key trait for determining how organisms influence their ecosystems. Using mass-balance, ecological stoichiometry predicts that animals with higher concentrations of element X will selectively retain more X and will recycle less X in their waste than animals with lower X concentrations. These animals will also store high quantities of X during their lives and after their deaths (prior to full decomposition). 2. Vertebrates may uniquely impact nutrient cycling because...

The Revised Identification of Seniors At Risk screening tool predicts readmission in older hospitalized patients: a cohort study

Jane McCusker, Rebecca N. Warburton, Sylvie D. Lambert, Eric Belzile & Manon de Raad
Abstract Background The Identification of Seniors at Risk (ISAR) screening tool is a widely-used risk stratification tool for older adults in the emergency department (ED). Few studies have investigated the use of ISAR to predict outcomes of hospitalized patients. To improve usability a revised version of ISAR (ISAR-R), was developed in a quality improvement project. The ISAR-R is also widely used, although never formally validated. To address these two gaps in knowledge, we aimed to...

Additional file 1 of PrEP-related stigma and PrEP use among gay, bisexual and other men who have sex with men in Ontario and British Columbia, Canada

Oscar Javier Pico-Espinosa, Mark Hull, Paul MacPherson, Daniel Grace, Mark Gaspar, Nathan Lachowsky, Saira Mohammed, James Demers, Marshall Kilduff, Robinson Truong & Darrell H. S. Tan
Supplementary Figures and Tables.

Is Neoliberalism Killing Us? A Cross Sectional Study of the Impact of Neoliberal Beliefs on Health and Social Wellbeing in the Midst of the COVID-19 Pandemic

Kiffer G. Card & Kirk J. Hepburn
Neoliberal ideology is linked to poorer collective health and well-being. At the individual level, however, neoliberal beliefs may actually promote self-efficacy, self-esteem, and self-reliance. We examined the effects of three beliefs underlying neoliberalism—(a) Personal Wherewithal, (b) Natural Competition, and (c) Anti-Government Interference—to understand the unique pathways by which neoliberalism affects health and well-being at the individual level. Participants were recruited using paid advertisements on social media in May/June 2020. Multivariable regression identified associations between each...

Exploring the Composite Intentionality of 3D Printers and Makers in Digital Fabrication

Sowmya Somanath, Ron Wakkary, Omid Ettehadi, Henry Lin, Armi Behzad, Jordan Eshpeter & Doenja Oogjes

Molecular dynamics simulation study on the inhibitory mechanism of RIPK1 by 4,5-dihydropyrazole derivatives

Yurou Zhang, Song Wang, Aimin Ren, Shanshan Guan, E Jingwen, Zhijian Luo, Zhijie Yang, Xinyue Zhang, Juan Du & Hao Zhang
The receptor-interacting serine/threonine protein kinase 1 (RIPK1) is tightly related to Digestive System Neoplasms genesis. Therefore, inhibitors that target RIPK1 have gained popularity in today's anti-cancer therapy. Molecular docking, molecular dynamics simulations, and molecular mechanics/Poisson-Boltzmann surface area calculations were used to investigate the binding mode and inhibition mechanism of five 4,5-dihydropyrazole derivatives with RIPK1 in the present work. The results showed that the five inhibitors mainly interacted with RIPK1 through van der Waals interaction and...

Supplemental Material for Rondeau et al., 2022

Eric B. Rondeau, Kris A. Christensen, David R. Minkley, Jong S. Leong, Michelle T.T. Chan, Cody A. Despins, Anita Mueller, Dionne Sakhrani, Carlo A. Biagi, Quentin Rougemont, Eric Normandeau, Steven J.M. Jones, Robert H. Devlin, Ruth E. Withler, Terry D. Beacham, Kerry A. Naish, José M. Yáñez, Roberto Neira, Louis Bernatchez, William S. Davidson & Ben F. Koop
Nucleotide variants were called using GATK version 3.8 with the coho salmon RefSeq genome assembly GCF_002021735.2 (GenBank assembly accession GCA_002021735.2). Samples were from the following NCBI BioProjects: PRJNA401427 and PRJNA808051.

Synthesis of New Trisulfonated Calix[4]arenes Functionalized at the Upper Rim, and Their Complexation with the Trimethyllysine Epigenetic Mark

Kevin D. Daze, Manuel C. F. Ma, Florent Pineux & Fraser Hof
A synthetic route to produce a new family of trisulfonated calix[4]arenes bearing a single group, selectively introduced, that lines the binding pocket is reported. Ten examples, including new sulfonamide and biphenyl-substituted hosts, each with additional binding elements, demonstrate the tuning of guest affinities and selectivities. NMR titrations in phosphate-buffered water show that one of the new hosts binds to the modified amino acid trimethyllysine with the highest affinity and selectivity observed to date.

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