87 Works

Data from: Distribution and population structure of the anther smut fungus Microbotryum silenes-acaulis parasitizing an arctic-alpine plant

Britta Bueker, Chris Eberlein, Pierre Gladieux, Angela Schaefer, Alodie Snirc, Dominic Bennett, Dominik Begerow, Michael Hood, Tatiana Giraud & Dominic J. Bennett
Cold-adapted organisms with current arctic-alpine distributions have persisted during the last glaciation in multiple ice-free refugia, leaving footprints in their population structure that contrast with temperate plants and animals. However, pathogens that live within hosts having arctic-alpine distributions have been little studied. Here, we therefore investigated the geographical range and population structure of a fungus parasitizing an arctic-alpine plant. A total of 1437 herbarium specimens of the plant Silene acaulis were examined, and the anther...

Psychophysiological stress response and memory in borderline personality disorder

Moritz Duesenberg, Oliver T. Wolf, Sophie Metz, Stefan Roepke, Juliane Fleischer, Valentina Elias, Babette Renneberg, Christian Otte & Katja Wingenfeld
Background: Previously, we found that patients with borderline personality disorder (BPD) but not healthy controls (HC) showed improved memory retrieval after hydrocortisone administration. Objective: In this study, we examined whether increases in endogenous cortisol after psychosocial stress are associated with memory function in patients with BPD and in healthy individuals. Methods: We recruited 49 female patients with BPD and 49 female HC. All participants were exposed to a psychosocial stressor, the Trier Social Stress Test...

Psychophysiological stress response and memory in borderline personality disorder

Moritz Duesenberg, Oliver T. Wolf, Sophie Metz, Stefan Roepke, Juliane Fleischer, Valentina Elias, Babette Renneberg, Christian Otte & Katja Wingenfeld
Background: Previously, we found that patients with borderline personality disorder (BPD) but not healthy controls (HC) showed improved memory retrieval after hydrocortisone administration. Objective: In this study, we examined whether increases in endogenous cortisol after psychosocial stress are associated with memory function in patients with BPD and in healthy individuals. Methods: We recruited 49 female patients with BPD and 49 female HC. All participants were exposed to a psychosocial stressor, the Trier Social Stress Test...

Connotations - A Journal for Critical Debate (Vol. 28)

Inge Leimberg, Matthias Bauer, Burkhard Niederhoff & Angelika Zirker

Association of gray matter atrophy patterns with clinical phenotype and progression in multiple sclerosis

Maria A Rocca, Paola Valsasina, Alessandro Meani, Claudio Gobbi, Chiara Zecca, Alex Rovira, Jaume Sastre-Garriga, Hugh Kearney, Olga Ciccarelli, Lucy Matthews, Jacqueline Palace, Antonio Gallo, Alvino Bisecco, Carsten Lukas, Barbara Bellenberg, Frederik Barkhof, Hugo Vrenken, Paolo Preziosa & Massimo Filippi
Objectives. Grey matter (GM) involvement is clinically relevant in multiple sclerosis (MS). Using source-based morphometry (SBM), we characterized GM atrophy and its 1-year evolution across different MS phenotypes. Methods. Clinical and MRI data were obtained at 8 European sites from 170 healthy controls (HCs) and 398 MS patients (34 clinically isolated syndromes [CIS], 226 relapsing-remitting [RR], 95 secondary progressive [SP] and 43 primary progressive [PP] MS). Fifty-seven HC and 144 MS underwent 1-year follow-up. Baseline...

Repositories for taxonomic data: Where we are and what is missing

Aurélien Miralles, Teddy Bruy, Katherine Wolcott, Mark Scherz, Dominik Begerow, Bank Beszteri, Michael Bonkowski, Janine Felden, Birgit Gemeinholzer, Frank Glaw, Frank Oliver Glöckner, Oliver Hawlitschek, Ivaylo Kostadinov, Tim Nattkemper, Christian Printzen, Jasmin Renz, Nataliya Rybalka, Marc Stadler, Tanja Weibulat, Thomas Wilke, Susanne Renner & Miguel Vences
Natural history collections are leading successful large-scale projects of specimen digitization (images, metadata, DNA barcodes), transforming taxonomy into a big data science. Yet, little effort has been directed towards safeguarding and subsequently mobilizing the considerable amount of original data generated during the process of naming 15–20,000 species every year. From the perspective of alpha-taxonomists, we provide a review of the properties and diversity of taxonomic data, assess their volume and use, and establish criteria for...

Data from: Evolutionary–phylogenetic pathway of the Cretaceous ammonite genus Aegocrioceras and its relationship to Juddiceras spp. and Crioceratites spp.

Manuel F. G. Weinkauf, René Hoffmann & Kurt Wiedenroth
The systematics of ammonoids are complicated by their large degree of intra-specific variation, which complicates a stable validation of species. Aegocrioceras is a heteromorph ammonite from the Lower Saxony Basin in the Hauterivian Boreal, and a prime example of a genus with an unstable internal systematic and external relationship to other ammonoids. Here, we use quantitative morphometrics on Aegocrioceras species from an assemblage collected in the clay pit Resse (north-west Germany) to evaluate the systematics...

Ethical codes of conduct in journalism: Demands for a digitalising mediascape

Joaquim Fidalgo, Barbara Thomass, Christian Ruggiero, Mauro Bomba, Simone Sallusti & Torbjörn von Krogh

XI. Nación y Nacionalismo

Yasmin Temelli (ed.) & Gustavo Leyva (ed.)
143 pp.

Hydrothermal processes related to submarine iron ore formation: Insights from Devonian Lahn-Dill-type ores

Leanne Schmitt , Thomas Kirnbauer , Thomas Angerer , Dennis Kraemer & Sabine Klein
Numerous studies on submarine iron-rich sediments (BIF, ironstones, etc.) focus on environmental changes and ocean chemistry, however, many questions related to underlying hydrothermal processes remain unresolved. As proximal chemical sediments, Lahn-Dill-type iron ores can provide insight into mechanisms of hydrothermal seafloor alteration related metal scavenging, and subsequent Fe-mineral deposition. Lahn-Dill-type iron ores formed during the Middle/Upper Devonian within the Rhenohercynian back-arc basin associated with intraplate alkali basaltic volcanism. Ores formed on top of volcanogenic successions...

Gesellschaftliche Spaltung von Anfang an?!

Nora Jehles, Katharina Knüttel & Jakob Schuchardt
Wie groß ist das Ausmaß von Kita-Segregation in Deutschland? Dieser Frage geht der vorliegende Bericht nach und beschreibt empirische Befunde einer quantitativen Analyse von Kita-Segregation auf verschiedenen föderalen Ebenen. Es wird untersucht, wie sich strukturelle Bedingungen der Jugendämter auswirken und welche Aspekte im Umgang mit Kita-Segregation zu beachten sind. Nicht erst seit der Corona-Pandemie wird diskutiert, inwiefern sich die Gesellschaft in verschiedenen Teilbereichen polarisiert. Während die soziale Spaltung von Städten bzw. Stadtteilen oder Schulen relativ...

Preserved T-cell response in anti-CD20-treated multiple sclerosis patients following SARS-CoV-2 vaccination

Simon Faissner, Neele Heitmann, Ricarda Rohling, Ulas Ceylan, Marielena Bongert, Carlos Plaza-Sirvent, Corinna Marheinecke, Xiomara Pedreiturria, Ilya Ayzenberg, Kerstin Hellwig, Ingo Schmitz, Stephanie Pfaender & Ralf Gold
Background:The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has tremendous implications for the management of patients with autoimmune conditions such as multiple sclerosis (MS) under immune therapies targeting CD20+ B cells (aCD20).Objectives:Here, we investigated humoral and cellular immune responses, including anti-spike titers, neutralization against SARS-CoV-2 wild-type (WT), delta, and omicron variant and T cell responses of aCD20-treated relapsing–remitting MS patients following SARS-CoV-2 vaccination compared with healthy controls.Methods:Blood samples were collected within 4–8 weeks following...

An environmental DNA metabarcoding approach versus a visual survey for reefs of Koh Pha‐ngan in Thailand

Fabian Gösser, Maximilian Schweinsberg, Pierre Mittelbach, Eike Schoenig & Ralph Tollrian
Information on diversity indices and abundance of individual species is crucial for the assessment of ecosystem health, especially for endangered ecosystems such as coral reefs. The application of environmental DNA (eDNA) to monitor coral biodiversity is, however, just beginning to come into focus for marine biologists. In this study, an eDNA metabarcoding approach of seawater samples in three different reefs on Koh Pha-ngan, Thailand, was compared with simultaneously collected visual census data. In addition, differences...

Groundwater quality: new developments on understanding transport and mobility of contaminants related to anthropogenic impacts.

Tobias Licha & Ferry Schiperski
Groundwater quality is widely compromised by anthropogenic impact. This becomes evident by the presence of numerous anthropogenic organic and inorganic contaminants in groundwater. Contaminants are of widespread origin. They enter the groundwater associated to different processes such as sewer failure, agricultural activities or contaminated industrial sites. Understanding the input mechanism, transport, attenuation and degradation processes in short and long term is crucial for sustainable groundwater development. Although unwanted, contaminants even in smallest quantities might provide...

Separable gain control of ongoing and evoked activity in the visual cortex by serotonergic input

Zohre Azimi, Ruxandra Barzan, Katharina Spoida, Tatjana Surdin, Patric Wollenweber, Melanie D. Mark, Stefan Herlitze & Dirk Jancke
Controlling gain of cortical activity is essential to modulate weights between internal ongoing communication and external sensory drive. Here, we show that serotonergic input has separable suppressive effects on the gain of ongoing and evoked visual activity. We combined optogenetic stimulation of the dorsal raphe nucleus (DRN) with wide-field calcium imaging, extracellular recordings, and iontophoresis of serotonin (5-HT) receptor antagonists in the mouse primary visual cortex. 5-HT1A receptors promote divisive suppression of spontaneous activity, while...

Data from: Biocultural approaches to sustainability: a systematic review of the scientific literature

Jan Hanspach, L. Jamila Haider, Elisa Oteris-Rozas, Anton Stahl Olafsson, Natalie Gulsrud, Chris Raymond, Mario Torralba, Berta Martín-López, Claudia Bieling, María García Martín, Christian Albert, Thomas Beery, Nora Fagerholm, Isabel Díaz-Reviriego, Annika Drews-Shambroom & Tobias Plieninger
Current sustainability challenges demand approaches that acknowledge a plurality of human-nature interactions and worldviews, for which biocultural approaches are considered appropriate and timely. This systematic review analyses the application of biocultural approaches to sustainability in scientific journal articles published between 1990 and 2018 through a mixed methods approach combining qualitative content analysis and quantitative multivariate methods. The study identifies seven distinct biocultural lenses, i.e. different ways of understanding and applying biocultural approaches, which to different...

Data from: Metabolites of n-Butylparaben and iso-Butylparaben exhibit estrogenic properties in MCF-7 and T47D human breast cancer cell lines

Thomas L. Gonzalez, Rebecca K. Moos, Christina L. Gercsh, Michael D. Johnson, Rudy J. Richardson, Holger M. Koch, James M. Rae & Christina L Gersch
Two oxidized metabolites of n-butylparaben (BuP) and iso-butylparaben (IsoBuP) discovered in human urine samples exhibit structural similarity to endogenous estrogens. We hypothesized that these metabolites bind to the human estrogen receptor (ER) and promote estrogen signaling. We tested this using models of ER-mediated cellular proliferation. The estrogenic properties of 3-hydroxy n-butyl 4-hydroxybenzoate (3OH) and 2-hydroxy iso-butyl 4-hydroxybenzoate (2OH) were determined using the ER-positive, estrogen-dependent human breast cancer cell lines MCF-7, and T47D. The 3OH metabolite...

2.8.3. Biopsychosoziale Zusammenhänge bei Verdauungsstörungen und chronischen viszeralen Schmerzen

Sigrid Elsenbruch & Sven Benson
Kapitel im Online Lehrbuch der Medizinischen Psychologie und Medizinischen Soziologie

Transcriptional response of mushrooms to artificial sun exposure

Franz-Sebastian Krah, Jaqueline Hess, Florian Hennicke, Ritwika Kar & Claus Bässler
Climate change causes increased tree mortality leading to canopy loss and thus sun-exposed forest floors. Sun exposure creates extreme temperatures and radiation, with potentially more drastic effects on forest organisms than the current increase in mean temperature. Such conditions might potentially negatively affect the maturation of mushrooms of forest fungi. A failure of reaching maturation would mean no sexual spore release and, thus, entail a loss of genetic diversity. However, we currently have a limited...

Finanzen und soziale Sicherung – Zukunftsperspektiven für den Sozialstaat

Thieß Petersen, Martin Werding, Andreas Esche & Anastasia Hamburg
Die Alterung der Gesellschaft setzt die öffentlichen Finanzen enorm unter Druck und zieht steigende Sozialversicherungsbeiträge nach sich, die jüngeren und zukünftigen Generationen erhebliche finanzielle Belastungen aufbürden. Dieser Policy Brief fasst die zentralen Ergebnisse unserer Studie „Demografische Alterung und öffentliche Finanzen. Wie geht es nach der Covid-19-Krise weiter?“ kompakt zusammen und zeigt, welche politischen Weichenstellungen notwendig sind, um die ökonomischen Kosten der demografischen Alterung zu dämpfen.

Editorial: Nación y Nacionalismo

Yasmin Temelli (ed.) & Gustavo Leyva (ed.)
pp. 4-13.

Public service media: Exploring the influence of strong public service media on democracy

Barbara Thomass, Joaquim Fidalgo, John Grönvall, Achilleas Karadimitriou & Lars Nord

Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium

Pål Møller, Toni Seppälä, James G. Dowty, Saskia Haupt, Mev Dominguez-Valentin, Lone Sunde, Inge Bernstein, Christoph Engel, Stefan Aretz, Maartje Nielsen, Gabriel Capella, Dafydd Gareth Evans, John Burn, Elke Holinski-Feder, Lucio Bertario, Bernardo Bonanni, Annika Lindblom, Zohar Levi, Finlay Macrae, Ingrid Winship, John-Paul Plazzer, Rolf Sijmons, Luigi Laghi, Adriana Della Valle, Karl Heinimann … & Mark A. Jenkins
Abstract Objective To compare colorectal cancer (CRC) incidences in carriers of pathogenic variants of the MMR genes in the PLSD and IMRC cohorts, of which only the former included mandatory colonoscopy surveillance for all participants. Methods CRC incidences were calculated in an intervention group comprising a cohort of confirmed carriers of pathogenic or likely pathogenic variants in mismatch repair genes (path_MMR) followed prospectively by the Prospective Lynch Syndrome Database (PLSD). All had colonoscopy surveillance, with...

ISIMIP3b water abstraction input data

Yoshihide Wada, Martina Flörke, Naota Hanasaki, Hannes Müller Schmied, Simon N. Gosling & Jacob Schewe
This data is based on ISIMIP2a varsoc simulations for 1901-2005, and on RCP6.0 simulations from the Water Futures and Solutions project (Wada et al., 2016) for after 2005. Years before 1901 have been filled with the value for the year 1901.

sj-docx-1-cpx-10.1177_21677026221101379 – Supplemental material for Change of Threat Expectancy as Mechanism of Exposure-Based Psychotherapy for Anxiety Disorders: Evidence From 8,484 Exposure Exercises of 605 Patients

Andre Pittig, Ingmar Heinig, Stephan Goerigk, Jan Richter, Maike Hollandt, Ulrike Lueken, Paul Pauli, Jürgen Deckert, Tilo Kircher, Benjamin Straube, Peter Neudeck, Katja Koelkebeck, Udo Dannlowski, Volker Arolt, Thomas Fydrich, Lydia Fehm, Andreas Ströhle, Christina Totzeck, Jürgen Margraf, Silvia Schneider, Jürgen Hoyer, Winfried Rief, Michelle G. Craske, Alfons O. Hamm & Hans-Ulrich Wittchen
Supplemental material, sj-docx-1-cpx-10.1177_21677026221101379 for Change of Threat Expectancy as Mechanism of Exposure-Based Psychotherapy for Anxiety Disorders: Evidence From 8,484 Exposure Exercises of 605 Patients by Andre Pittig, Ingmar Heinig, Stephan Goerigk, Jan Richter, Maike Hollandt, Ulrike Lueken, Paul Pauli, Jürgen Deckert, Tilo Kircher, Benjamin Straube, Peter Neudeck, Katja Koelkebeck, Udo Dannlowski, Volker Arolt, Thomas Fydrich, Lydia Fehm, Andreas Ströhle, Christina Totzeck, Jürgen Margraf, Silvia Schneider, Jürgen Hoyer, Winfried Rief, Michelle G. Craske, Alfons O. Hamm...

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