Supplemental material, sj-docx-2-whe-10.1177_17455057221130566 for Endometriosis prevalence and incidence trends in a large population-based study in Catalonia (Spain) from 2009 to 2018 by Laura Medina-Perucha, Andrea Pistillo, Berta Raventós, Constanza Jacques-Aviñó, Jordina Munrós-Feliu, Cristina Martínez-Bueno, Carme Valls-Llobet, Francisco Carmona, Tomàs López-Jiménez, Georgina Pujolar-Díaz, Eva Flo Arcas, Anna Berenguera and Talita Duarte-Salles in Women’s Health

Supplemental material, sj-docx-2-whe-10.1177_17455057221130566 for Endometriosis prevalence and incidence trends in a large population-based study in Catalonia (Spain) from 2009 to 2018 by Laura Medina-Perucha, Andrea Pistillo, Berta Raventós, Constanza Jacques-Aviñó, Jordina Munrós-Feliu, Cristina Martínez-Bueno, Carme Valls-Llobet, Francisco Carmona, Tomàs López-Jiménez, Georgina Pujolar-Díaz, Eva Flo Arcas, Anna Berenguera and Talita Duarte-Salles in Women’s Health

Supplemental material, sj-docx-3-whe-10.1177_17455057221130566 for Endometriosis prevalence and incidence trends in a large population-based study in Catalonia (Spain) from 2009 to 2018 by Laura Medina-Perucha, Andrea Pistillo, Berta Raventós, Constanza Jacques-Aviñó, Jordina Munrós-Feliu, Cristina Martínez-Bueno, Carme Valls-Llobet, Francisco Carmona, Tomàs López-Jiménez, Georgina Pujolar-Díaz, Eva Flo Arcas, Anna Berenguera and Talita Duarte-Salles in Women’s Health

Abstract This study evaluated the persistence of IgM, IgA, and IgG to SARS-CoV-2 spike and nucleocapsid antigens up to 616 days since the onset of symptoms in a longitudinal cohort of 247 primary health care workers from Barcelona, Spain, followed up since the start of the pandemic. The study also assesses factors affecting antibody levels, including comorbidities and the responses to variants of concern as well as the frequency of reinfections. Despite a gradual and...

Abstract Background The incidence of sepsis can be estimated between 250 and 500 cases/100.000 people per year and is responsible for up to 6% of total hospital admissions. Identified as one of the most relevant global health problems, sepsis is the condition that generates the highest costs in the healthcare system. Important changes in the management of septic patients have been included in recent years; however, there is no information about how changes in the...

Supplemental material, sj-docx-1-whe-10.1177_17455057221130566 for Endometriosis prevalence and incidence trends in a large population-based study in Catalonia (Spain) from 2009 to 2018 by Laura Medina-Perucha, Andrea Pistillo, Berta Raventós, Constanza Jacques-Aviñó, Jordina Munrós-Feliu, Cristina Martínez-Bueno, Carme Valls-Llobet, Francisco Carmona, Tomàs López-Jiménez, Georgina Pujolar-Díaz, Eva Flo Arcas, Anna Berenguera and Talita Duarte-Salles in Women’s Health

Supplemental material, sj-docx-4-whe-10.1177_17455057221130566 for Endometriosis prevalence and incidence trends in a large population-based study in Catalonia (Spain) from 2009 to 2018 by Laura Medina-Perucha, Andrea Pistillo, Berta Raventós, Constanza Jacques-Aviñó, Jordina Munrós-Feliu, Cristina Martínez-Bueno, Carme Valls-Llobet, Francisco Carmona, Tomàs López-Jiménez, Georgina Pujolar-Díaz, Eva Flo Arcas, Anna Berenguera and Talita Duarte-Salles in Women’s Health

Supplemental material, sj-docx-4-whe-10.1177_17455057221130566 for Endometriosis prevalence and incidence trends in a large population-based study in Catalonia (Spain) from 2009 to 2018 by Laura Medina-Perucha, Andrea Pistillo, Berta Raventós, Constanza Jacques-Aviñó, Jordina Munrós-Feliu, Cristina Martínez-Bueno, Carme Valls-Llobet, Francisco Carmona, Tomàs López-Jiménez, Georgina Pujolar-Díaz, Eva Flo Arcas, Anna Berenguera and Talita Duarte-Salles in Women’s Health

Supplemental material, sj-docx-1-whe-10.1177_17455057221130566 for Endometriosis prevalence and incidence trends in a large population-based study in Catalonia (Spain) from 2009 to 2018 by Laura Medina-Perucha, Andrea Pistillo, Berta Raventós, Constanza Jacques-Aviñó, Jordina Munrós-Feliu, Cristina Martínez-Bueno, Carme Valls-Llobet, Francisco Carmona, Tomàs López-Jiménez, Georgina Pujolar-Díaz, Eva Flo Arcas, Anna Berenguera and Talita Duarte-Salles in Women’s Health

Additional file 1: Figure S1. Odds ratio for the association between mortality (1A–C), intensive care unit admission (2A–C) and use of invasive mechanical ventilation during the hospitalization (3A–C) and ischemic heart disease in each of the four cohorts and overall. I2 indicates heterogeneity in the estimates. Odds ratio estimates adjusted for: model 1: age and sex (B); model 2: model 1 + type of diabetes, arterial hypertension, and the presence of microvascular disease (C).

Additional file 3: Figure S3. Odds ratio for the association between mortality (1A–C), intensive care unit admission (2A–C) and peripheral artery disease in each of the four cohorts and overall. I2 indicates heterogeneity in the estimates. Odds ratio estimates adjusted for: model 1: age and sex (B); model 2: model 1 + type of diabetes, arterial hypertension, and the presence of microvascular disease (C).

Additional file 2: Figure S2. Odds ratio for the association between mortality (1A–C), intensive care unit admission (2A–C) and and stroke in each of the four cohorts and overall. I2 indicates heterogeneity in the estimates. Odds ratio estimates adjusted for: model 1: age and sex (B); model 2: model 1 + type of diabetes, arterial hypertension, and the presence of microvascular disease (C).

Abstract Background It is not clear whether pre-existing macrovascular complications (ischemic heart disease, stroke or peripheral artery disease) are associated with health outcomes in people with diabetes mellitus hospitalized for COVID-19. Methods We conducted cohort studies of adults with pre-existing diabetes hospitalized for COVID-19 infection in the UK, France, and Spain during the early phase of the pandemic (between March 2020—October 2020). Logistic regression models adjusted for demographic factors and other comorbidities were used to...

Abstract Background The incidence of sepsis can be estimated between 250 and 500 cases/100.000 people per year and is responsible for up to 6% of total hospital admissions. Identified as one of the most relevant global health problems, sepsis is the condition that generates the highest costs in the healthcare system. Important changes in the management of septic patients have been included in recent years; however, there is no information about how changes in the...

Additional file 1. ICD‑9‑MC codes used to identify infectious process, site of infection, acute organ dysfunction and procedures used in intensive care unit.

Additional file 3: Figure S3. Odds ratio for the association between mortality (1A–C), intensive care unit admission (2A–C) and peripheral artery disease in each of the four cohorts and overall. I2 indicates heterogeneity in the estimates. Odds ratio estimates adjusted for: model 1: age and sex (B); model 2: model 1 + type of diabetes, arterial hypertension, and the presence of microvascular disease (C).

Objective:Endometriosis greatly impacts women’s health and quality of life. However, research on the prevalence and incidence of endometriosis remains inconclusive. This study assesses time trends in the prevalence and incidence of endometriosis diagnoses in Catalonia (Spain) from 2009 to 2018, considering differences by age and socioeconomic status.Methods:Population-based cohort study using data from the Information System for Research in Primary Care (SIDIAP) database. Data were included from over 2.4 million women aged 15–55 years between 1...

Objective:Endometriosis greatly impacts women’s health and quality of life. However, research on the prevalence and incidence of endometriosis remains inconclusive. This study assesses time trends in the prevalence and incidence of endometriosis diagnoses in Catalonia (Spain) from 2009 to 2018, considering differences by age and socioeconomic status.Methods:Population-based cohort study using data from the Information System for Research in Primary Care (SIDIAP) database. Data were included from over 2.4 million women aged 15–55 years between 1...

Additional file 1: Table S1. Association of baseline variables and comorbidities with levels of SARS-CoV-2 antibodies at time point 4 (January-February 2021) prior to the massive rollout of vaccination. Table S2. Seropositivity against the SARS-CoV-2 receptor-binding domain antigen from variants of concern. Table S3. Reinfections. Table S4. Significant associations of baseline variables with differential antibody rate of change. Fig. S1. Overall distribution of antibody responses for each isotype and antigen pair of the 128 pre-pandemic...

Additional file 1: Table S1. Association of baseline variables and comorbidities with levels of SARS-CoV-2 antibodies at time point 4 (January-February 2021) prior to the massive rollout of vaccination. Table S2. Seropositivity against the SARS-CoV-2 receptor-binding domain antigen from variants of concern. Table S3. Reinfections. Table S4. Significant associations of baseline variables with differential antibody rate of change. Fig. S1. Overall distribution of antibody responses for each isotype and antigen pair of the 128 pre-pandemic...

Abstract This study evaluated the persistence of IgM, IgA, and IgG to SARS-CoV-2 spike and nucleocapsid antigens up to 616 days since the onset of symptoms in a longitudinal cohort of 247 primary health care workers from Barcelona, Spain, followed up since the start of the pandemic. The study also assesses factors affecting antibody levels, including comorbidities and the responses to variants of concern as well as the frequency of reinfections. Despite a gradual and...

Additional file 1. ICD‑9‑MC codes used to identify infectious process, site of infection, acute organ dysfunction and procedures used in intensive care unit.

Supplemental material, sj-docx-3-whe-10.1177_17455057221130566 for Endometriosis prevalence and incidence trends in a large population-based study in Catalonia (Spain) from 2009 to 2018 by Laura Medina-Perucha, Andrea Pistillo, Berta Raventós, Constanza Jacques-Aviñó, Jordina Munrós-Feliu, Cristina Martínez-Bueno, Carme Valls-Llobet, Francisco Carmona, Tomàs López-Jiménez, Georgina Pujolar-Díaz, Eva Flo Arcas, Anna Berenguera and Talita Duarte-Salles in Women’s Health

Additional file 1: Figure S1. Odds ratio for the association between mortality (1A–C), intensive care unit admission (2A–C) and use of invasive mechanical ventilation during the hospitalization (3A–C) and ischemic heart disease in each of the four cohorts and overall. I2 indicates heterogeneity in the estimates. Odds ratio estimates adjusted for: model 1: age and sex (B); model 2: model 1 + type of diabetes, arterial hypertension, and the presence of microvascular disease (C).

Additional file 2: Figure S2. Odds ratio for the association between mortality (1A–C), intensive care unit admission (2A–C) and and stroke in each of the four cohorts and overall. I2 indicates heterogeneity in the estimates. Odds ratio estimates adjusted for: model 1: age and sex (B); model 2: model 1 + type of diabetes, arterial hypertension, and the presence of microvascular disease (C).