28 Works

Heavy-load exercise in older adults activates vasculogenesis and has a stronger impact on muscle gene expression than in young adults

Kaare M. Gautvik, Ole K. Olstad, Ulrika Raue, Vigdis T. Gautvik, Karl J. Kvernevik, Tor P. Utheim, Solveig Ravnum, Camilla Kirkegaard, Håvard Wiig, Garan Jones, Luke C. Pilling, Scott Trappe, Truls Raastad & Sjur Reppe
Abstract Background A striking effect of old age is the involuntary loss of muscle mass and strength leading to sarcopenia and reduced physiological functions. However, effects of heavy-load exercise in older adults on diseases and functions as predicted by changes in muscle gene expression have been inadequately studied. Methods Thigh muscle global transcriptional activity (transcriptome) was analyzed in cohorts of older and younger adults before and after 12–13 weeks heavy-load strength exercise using Affymetrix microarrays....

Men’s perception of information and descriptions of emotional strain in the diagnostic phase of prostate cancer—a qualitative individual interview study

Maja Elisabeth Juul Søndergaard, Kirsten Lode, Svein Reidar Kjosavik & Sissel Eikeland Husebø
To explore men`s perception of information and their possible emotional strain in the diagnostic phase of prostate cancer. A qualitative explorative research design was employed. Data were collected from June to November 2017. The study was set at a urological outpatient clinic at a university hospital in Norway. Semi-structured interviews were conducted with ten men who had been examined for prostate cancer. Interviews were analyzed using Systematic Text Condensation (STC). The analysis revealed three themes....

Newborn resuscitation simulation training and changes in clinical performance and perinatal outcomes: a clinical observational study of 10,481 births

May Sissel Vadla, Robert Moshiro, Paschal Mdoe, Joar Eilevstjønn, Jan Terje Kvaløy, Barikiel Hhando Hhoki & Hege Ersdal
Abstract Background Annually, 1.5 million intrapartum-related deaths occur; fresh stillbirths and early newborn deaths. Most of these deaths are preventable with skilled ventilation starting within the first minute of life. Helping Babies Breathe is an educational program shown to improve simulated skills in newborn resuscitation. However, translation into clinical practice remains a challenge. The aim was to describe changes in clinical resuscitation and perinatal outcomes (i.e., fresh stillbirths and 24-h newborn deaths) after introducing a...

Additional file 3 of Men’s perception of information and psychological distress in the diagnostic phase of prostate cancer: a comparative mixed methods study

Maja Elisabeth Juul Søndergaard, Kirsten Lode, Sissel Eikeland Husebø, Ingvild Dalen & Svein Reidar Kjosavik
Additional file 3. Counts and percentages of patients with scores above threshold levels for the Hospital Anxiety and Depression Scale in the PSAagroup (n=130) and the Stockholm3 group (n=120).

State transition modeling of complex monitored health data

Jörn Schulz, Jan Terje Kvaløy, Kjersti Engan, Trygve Eftestøl, Samwel Jatosh, Hussein Kidanto & Hege Ersdal
This article considers the analysis of complex monitored health data, where often one or several signals are reflecting the current health status that can be represented by a finite number of states, in addition to a set of covariates. In particular, we consider a novel application of a non-parametric state intensity regression method in order to study time-dependent effects of covariates on the state transition intensities. The method can handle baseline, time varying as well...

Newborn resuscitation simulation training and changes in clinical performance and perinatal outcomes: a clinical observational study of 10,481 births

May Sissel Vadla, Robert Moshiro, Paschal Mdoe, Joar Eilevstjønn, Jan Terje Kvaløy, Barikiel Hhando Hhoki & Hege Ersdal
Abstract Background Annually, 1.5 million intrapartum-related deaths occur; fresh stillbirths and early newborn deaths. Most of these deaths are preventable with skilled ventilation starting within the first minute of life. Helping Babies Breathe is an educational program shown to improve simulated skills in newborn resuscitation. However, translation into clinical practice remains a challenge. The aim was to describe changes in clinical resuscitation and perinatal outcomes (i.e., fresh stillbirths and 24-h newborn deaths) after introducing a...

Additional file 2 of Men’s perception of information and psychological distress in the diagnostic phase of prostate cancer: a comparative mixed methods study

Maja Elisabeth Juul Søndergaard, Kirsten Lode, Sissel Eikeland Husebø, Ingvild Dalen & Svein Reidar Kjosavik
Additional file 2. Counts and percentages of patients with different response categories to the four patient experience items in the PSAagroup (n=130) and the Stockholm3 group (n=120).

State transition modeling of complex monitored health data

Jörn Schulz, Jan Terje Kvaløy, Kjersti Engan, Trygve Eftestøl, Samwel Jatosh, Hussein Kidanto & Hege Ersdal
This article considers the analysis of complex monitored health data, where often one or several signals are reflecting the current health status that can be represented by a finite number of states, in addition to a set of covariates. In particular, we consider a novel application of a non-parametric state intensity regression method in order to study time-dependent effects of covariates on the state transition intensities. The method can handle baseline, time varying as well...

Heavy-load exercise in older adults activates vasculogenesis and has a stronger impact on muscle gene expression than in young adults

Kaare M. Gautvik, Ole K. Olstad, Ulrika Raue, Vigdis T. Gautvik, Karl J. Kvernevik, Tor P. Utheim, Solveig Ravnum, Camilla Kirkegaard, Håvard Wiig, Garan Jones, Luke C. Pilling, Scott Trappe, Truls Raastad & Sjur Reppe
Abstract Background A striking effect of old age is the involuntary loss of muscle mass and strength leading to sarcopenia and reduced physiological functions. However, effects of heavy-load exercise in older adults on diseases and functions as predicted by changes in muscle gene expression have been inadequately studied. Methods Thigh muscle global transcriptional activity (transcriptome) was analyzed in cohorts of older and younger adults before and after 12–13 weeks heavy-load strength exercise using Affymetrix microarrays....

Additional file 1 of Heavy-load exercise in older adults activates vasculogenesis and has a stronger impact on muscle gene expression than in young adults

Kaare M. Gautvik, Ole K. Olstad, Ulrika Raue, Vigdis T. Gautvik, Karl J. Kvernevik, Tor P. Utheim, Solveig Ravnum, Camilla Kirkegaard, Håvard Wiig, Garan Jones, Luke C. Pilling, Scott Trappe, Truls Raastad & Sjur Reppe
Addiitional file 1: Figure S1. Comparison of transcript signal levels between os ilium–associated muscle and thigh muscle. Figure S2. Genes within the Diseases and Function category Vasculogenesis with increased (red) or reduced (green) expression end vs start of the training period in elderly as compared to young. Table S1. Common annotated genes changed in elderly in both Oslo and BSU cohorts at Q-value<0.1.

Additional file 1 of Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery

Miklosh Bala, Fausto Catena, Jeffry Kashuk, Belinda De Simone, Carlos Augusto Gomes, Dieter Weber, Massimo Sartelli, Federico Coccolini, Yoram Kluger, Fikri M. Abu-Zidan, Edoardo Picetti, Luca Ansaloni, Goran Augustin, Walter L. Biffl, Marco Ceresoli, Osvaldo Chiara, Massimo Chiarugi, Raul Coimbra, Yunfeng Cui, Dimitris Damaskos, Salomone Di Saverio, Joseph M. Galante, Vladimir Khokha, Andrew W. Kirkpatrick, Kenji Inaba … & Ernest E. Moore
Additional file 1: Table S3. Summary of the updated 2022 guidelines for AMI: statements and recommendations.

Additional file 1 of Newborn resuscitation simulation training and changes in clinical performance and perinatal outcomes: a clinical observational study of 10,481 births

May Sissel Vadla, Robert Moshiro, Paschal Mdoe, Joar Eilevstjønn, Jan Terje Kvaløy, Barikiel Hhando Hhoki & Hege Ersdal
Additional file 1. Master Trainer Guide. Information folder for master trainers (local champions) about how to prepare the equipment and perform ventilation training.

Men’s perception of information and psychological distress in the diagnostic phase of prostate cancer: a comparative mixed methods study

Maja Elisabeth Juul Søndergaard, Kirsten Lode, Sissel Eikeland Husebø, Ingvild Dalen & Svein Reidar Kjosavik
Abstract Background Previous studies indicate that men experience frustration and uncertainty when confronted with an elevated prostate specific antigen (PSA) test and during further diagnostics for prostate cancer. The novel Stockholm3 test is an algorithm-based test that combines plasma protein biomarkers, genetic markers and clinical variables in predicting the risk of PCa. The test was introduced in a western part of Norway as a new tool for detecting prostate cancer. This study aimed to explore...

Men’s perception of information and psychological distress in the diagnostic phase of prostate cancer: a comparative mixed methods study

Maja Elisabeth Juul Søndergaard, Kirsten Lode, Sissel Eikeland Husebø, Ingvild Dalen & Svein Reidar Kjosavik
Abstract Background Previous studies indicate that men experience frustration and uncertainty when confronted with an elevated prostate specific antigen (PSA) test and during further diagnostics for prostate cancer. The novel Stockholm3 test is an algorithm-based test that combines plasma protein biomarkers, genetic markers and clinical variables in predicting the risk of PCa. The test was introduced in a western part of Norway as a new tool for detecting prostate cancer. This study aimed to explore...

Additional file 3 of Men’s perception of information and psychological distress in the diagnostic phase of prostate cancer: a comparative mixed methods study

Maja Elisabeth Juul Søndergaard, Kirsten Lode, Sissel Eikeland Husebø, Ingvild Dalen & Svein Reidar Kjosavik
Additional file 3. Counts and percentages of patients with scores above threshold levels for the Hospital Anxiety and Depression Scale in the PSAagroup (n=130) and the Stockholm3 group (n=120).

Additional file 1 of Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery

Miklosh Bala, Fausto Catena, Jeffry Kashuk, Belinda De Simone, Carlos Augusto Gomes, Dieter Weber, Massimo Sartelli, Federico Coccolini, Yoram Kluger, Fikri M. Abu-Zidan, Edoardo Picetti, Luca Ansaloni, Goran Augustin, Walter L. Biffl, Marco Ceresoli, Osvaldo Chiara, Massimo Chiarugi, Raul Coimbra, Yunfeng Cui, Dimitris Damaskos, Salomone Di Saverio, Joseph M. Galante, Vladimir Khokha, Andrew W. Kirkpatrick, Kenji Inaba … & Ernest E. Moore
Additional file 1: Table S3. Summary of the updated 2022 guidelines for AMI: statements and recommendations.

Men’s perception of information and descriptions of emotional strain in the diagnostic phase of prostate cancer—a qualitative individual interview study

Maja Elisabeth Juul Søndergaard, Kirsten Lode, Svein Reidar Kjosavik & Sissel Eikeland Husebø
To explore men`s perception of information and their possible emotional strain in the diagnostic phase of prostate cancer. A qualitative explorative research design was employed. Data were collected from June to November 2017. The study was set at a urological outpatient clinic at a university hospital in Norway. Semi-structured interviews were conducted with ten men who had been examined for prostate cancer. Interviews were analyzed using Systematic Text Condensation (STC). The analysis revealed three themes....

Additional file 1 of Newborn resuscitation simulation training and changes in clinical performance and perinatal outcomes: a clinical observational study of 10,481 births

May Sissel Vadla, Robert Moshiro, Paschal Mdoe, Joar Eilevstjønn, Jan Terje Kvaløy, Barikiel Hhando Hhoki & Hege Ersdal
Additional file 1. Master Trainer Guide. Information folder for master trainers (local champions) about how to prepare the equipment and perform ventilation training.

Additional file 2 of Newborn resuscitation simulation training and changes in clinical performance and perinatal outcomes: a clinical observational study of 10,481 births

May Sissel Vadla, Robert Moshiro, Paschal Mdoe, Joar Eilevstjønn, Jan Terje Kvaløy, Barikiel Hhando Hhoki & Hege Ersdal
Additional file 2. Learner Guide. A simple introduction folder for midwives about how to perform ventilation skill training.

Data from: Impact of person-centred care training and person-centred activities on quality of life, agitation, and antipsychotic use in people with dementia living in nursing homes: a cluster-randomised controlled trial

Clive Ballard, Anne Corbett, Martin Orrell, Gareth Williams, Esme Moniz-Cook, Renee Romeo, Bob Woods, Lucy Garrod, Ingelin Testad, Barbara Woodward-Carlton, Jennifer Wenborn, Martin Knapp & Jane Fossey
Background: Agitation is a common, challenging symptom affecting large numbers of people with dementia and impacting on quality of life (QoL). There is an urgent need for evidence-based, cost-effective psychosocial interventions to improve these outcomes, particularly in the absence of safe, effective pharmacological therapies. This study aimed evaluate the efficacy of a person-centered care and psychosocial intervention (WHELD) on QoL, agitation and antipsychotic use in people with dementia living in nursing homes, and to determine...

Data from: Perinatal depression and anxiety in women with MS: a population-based cohort study

Karine Eid, Øivind F. Torkildsen, Jan Aarseth, Heidi Ø. Flemmen, Trygve Holmøy, Åslaug R. Lorentzen, Kjell-Morten Myhr, Trond Riise, Cecilia S. Simonsen, Cecilie F. Torkildsen, Stig Wergeland, Johannes S. Willumsen & Nina Øksendal
Objective: To assess the occurrence of perinatal depression and anxiety in women before and after diagnosis of multiple sclerosis (MS). Methods: 114,629 pregnant women were included in the Norwegian Mother, Father and Child Cohort study 1999–2008. We assessed depression and anxiety by questionnaires during and after pregnancy. Women with MS were identified from national health registries and hospital records and grouped into 1) MS diagnosed before pregnancy (n = 140), MS diagnosed after pregnancy with...

Additional file 1 of Men’s perception of information and psychological distress in the diagnostic phase of prostate cancer: a comparative mixed methods study

Maja Elisabeth Juul Søndergaard, Kirsten Lode, Sissel Eikeland Husebø, Ingvild Dalen & Svein Reidar Kjosavik
Additional file 1. Good Reporting of A Mixed Methods Study (GRAMMS*) Checklist.

Additional file 1 of Men’s perception of information and psychological distress in the diagnostic phase of prostate cancer: a comparative mixed methods study

Maja Elisabeth Juul Søndergaard, Kirsten Lode, Sissel Eikeland Husebø, Ingvild Dalen & Svein Reidar Kjosavik
Additional file 1. Good Reporting of A Mixed Methods Study (GRAMMS*) Checklist.

Additional file 2 of Men’s perception of information and psychological distress in the diagnostic phase of prostate cancer: a comparative mixed methods study

Maja Elisabeth Juul Søndergaard, Kirsten Lode, Sissel Eikeland Husebø, Ingvild Dalen & Svein Reidar Kjosavik
Additional file 2. Counts and percentages of patients with different response categories to the four patient experience items in the PSAagroup (n=130) and the Stockholm3 group (n=120).

Additional file 1 of Heavy-load exercise in older adults activates vasculogenesis and has a stronger impact on muscle gene expression than in young adults

Kaare M. Gautvik, Ole K. Olstad, Ulrika Raue, Vigdis T. Gautvik, Karl J. Kvernevik, Tor P. Utheim, Solveig Ravnum, Camilla Kirkegaard, Håvard Wiig, Garan Jones, Luke C. Pilling, Scott Trappe, Truls Raastad & Sjur Reppe
Addiitional file 1: Figure S1. Comparison of transcript signal levels between os ilium–associated muscle and thigh muscle. Figure S2. Genes within the Diseases and Function category Vasculogenesis with increased (red) or reduced (green) expression end vs start of the training period in elderly as compared to young. Table S1. Common annotated genes changed in elderly in both Oslo and BSU cohorts at Q-value<0.1.

Registration Year

  • 2022
    22
  • 2021
    3
  • 2019
    2
  • 2018
    1

Resource Types

  • Text
    18
  • Collection
    8
  • Dataset
    2

Affiliations

  • Stavanger University Hospital
    28
  • University of Stavanger
    18
  • University of Oslo
    7
  • Haydom Lutheran Hospital
    7
  • Sørlandet Hospital Arendal
    5
  • Massachusetts General Hospital
    4
  • Edinburgh Royal Infirmary
    4
  • University of Washington
    4
  • University of Newcastle Australia
    4
  • Ospedale Niguarda Ca' Granda
    4